IRIS
MACCHI, BEATRICE
 Distribuzione geografica
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Continente #
NA - Nord America 30.515
EU - Europa 2.214
AS - Asia 1.024
Continente sconosciuto - Info sul continente non disponibili 11
SA - Sud America 11
OC - Oceania 7
AF - Africa 3
Totale 33.785
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Nazione #
US - Stati Uniti d'America 30.501
SG - Singapore 454
UA - Ucraina 429
CN - Cina 403
DE - Germania 362
IT - Italia 353
IE - Irlanda 269
SE - Svezia 211
GB - Regno Unito 137
FR - Francia 133
RU - Federazione Russa 112
FI - Finlandia 97
KR - Corea 82
PL - Polonia 38
VN - Vietnam 34
ES - Italia 16
CA - Canada 14
BE - Belgio 10
NL - Olanda 10
PK - Pakistan 10
EU - Europa 9
IN - India 9
HK - Hong Kong 8
AU - Australia 7
CH - Svizzera 7
CL - Cile 7
CZ - Repubblica Ceca 6
JP - Giappone 6
GR - Grecia 5
TH - Thailandia 4
TR - Turchia 4
AL - Albania 3
AT - Austria 3
BR - Brasile 3
MA - Marocco 3
PH - Filippine 3
PT - Portogallo 3
RO - Romania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
IL - Israele 2
MD - Moldavia 2
NO - Norvegia 2
SK - Slovacchia (Repubblica Slovacca) 2
AR - Argentina 1
DK - Danimarca 1
JO - Giordania 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LB - Libano 1
UZ - Uzbekistan 1
Totale 33.785
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Città #
Woodbridge 9.189
Wilmington 8.445
Houston 7.495
Fairfield 999
Ann Arbor 559
Chandler 493
Ashburn 441
Seattle 381
Singapore 377
Jacksonville 369
Cambridge 327
Dublin 265
Medford 201
Dearborn 191
Beijing 147
Rome 145
Zhengzhou 118
Santa Clara 100
Lawrence 94
New York 79
Mülheim 57
San Diego 51
Boardman 42
Menlo Park 40
Kraków 35
Moscow 34
Milan 32
Dong Ket 30
Norwalk 26
Shanghai 26
Phoenix 22
Mountain View 20
Palo Alto 20
London 18
Nanjing 18
University Park 18
Redwood City 17
San Mateo 16
Kunming 14
Los Angeles 14
Falls Church 12
Verona 12
Brussels 10
Helsinki 10
Munich 10
Jinan 9
Lahore 9
Madrid 9
Toronto 9
Creede 8
Hefei 8
Indiana 8
Hong Kong 7
Nürnberg 7
Guangzhou 6
Nanchang 6
Saint Petersburg 6
Auburn Hills 5
Brno 5
Fuzhou 5
Hackensack 5
Hangzhou 5
Hounslow 5
Amsterdam 4
Clearwater 4
Frontone 4
Groningen 4
Hanoi 4
Hebei 4
Leawood 4
Messina 4
Napoli 4
Redmond 4
San Francisco 4
Xian 4
Athens 3
Atlanta 3
Bangkok 3
Changsha 3
Chengdu 3
Chicago 3
Kilburn 3
Padova 3
Pune 3
Seoul 3
Serrone 3
Tappahannock 3
Tirana 3
Treviso 3
Zurich 3
Acton 2
Agrate Conturbia 2
Bologna 2
Bratislava 2
Canberra 2
Carmagnola 2
Chisinau 2
Cosenza 2
Engelhard 2
Florence 2
Totale 31.254
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Nome #
Changes in apoptosis after interruption of potent antiretroviral therapy in patients with maximal HIV-1-RNA suppression 468
Thymosin α 1 potentiates the release by CD8(+) cells of soluble factors able to inhibit HIV-1 and human T lymphotropic virus 1 infection in vitro 449
Effect of phosphonated carbocyclic 2’-oxa-3’-aza-nucleoside on human T-cell leukemia virus type 1 infection in vitro 443
Inhibition of NF-κB activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis. 439
Approaches towards the synthesis of 7-halo-1,2-dihydroxyindolizidines (7-halolentiginosines) thwarting Grob fragmentation processes 439
INVECCHIAMENTO, IMMUNITÀ E FARMACI 439
D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent 436
AZT inhibits the transmission of human T cell leukaemia/lymphoma virus type I to adult peripheral blood mononuclear cells in vitro 432
Defective Fas ligand production in lymphocytes from MS patients 431
Thymosin alpha 1 and HIV-1: Recent advances and future perspectives 431
Spontaneous and anti-Fas-induced apoptosis in lymphocytes from HIV-infected patients undergoing highly active anti-retroviral therapy 430
Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides 429
Inflammatory and cell death pathways in brain and peripheral blood in Parkinson's disease 429
Interleukin 4 stimulates infection and temporary growth of human neonatal lymphocytes exposed in vitro to human T-lymphotropic virus type I, but fails to substitute for interleukin 2 in the immortalization of infected cultures 428
Testing anti-HIV activity of antiretroviral agents in vitro using flow cytometry analysis of CEM-GFP cells infected with transfection-derived HIV-1 NL4-3 428
Pharmacological and biological aspects of basic research on nucleoside-based reverse transcriptase inhibitors 422
Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis 417
Stereoselective Synthesis and Biological Evaluations of Novel 3 '-Deoxy-4 '-azaribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication 415
3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication 415
Decline of natural cytotoxicity of human lymphocytes following infection with human T-cell leukemia/lymphoma virus (HTLV) 414
Synthesis of phosphonated carbocyclic 2 '-oxa-3 '-aza-nucleosides: Novel inhibitors of reverse transcriptase 412
Interleukin 4 stimulates infection and temporary growth of human neonatal lymphocytes exposed in vitro to human T-lymphotropic virus type I, but fails to substitute for interleukin 2 in the immortalization of infected cultures 412
Telomerase activity of human peripheral blood mononuclear cells in the course of HTLV type 1 infection in Vitro 410
In vitro infection of CD4+ T lymphocytes with HTLV-I generates immortalized cell lines coexpressing lymphoid and myeloid cell markers 409
Inverse correlation between CD8+ lymphocyte apoptosis and CD4+ cell counts during potent antiretroviral therapy in HIV patients 407
Effect of human T lymphotropic retrovirus-I exposure on cultured human glioma cell lines 405
Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis 405
Programmed cell death and natural killer cells in multiple sclerosis: New potential therapeutic targets? 404
Synthesis, molecular modeling and biological evaluation of two new chicoric acid analogs 399
I FARMACI E LA FRAGILITA’ 396
Phosphonated nucleoside analogues as antiviral agents 393
Efficacy of 3 '-azido 3 ' deoxythymidine (AZT) in preventing HTLV-1 transmission to human cord blood mononuclear cells 391
Inflammation and programmed cell death in Alzheimer's disease: comparison of the central nervous system and peripheral blood 391
Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol 386
Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I) 384
Thymosin αlpha1 potentiatesthe release of antiviral factors by cd8+ cells: new tools for antiviral therapy 384
Simple and efficient synthesis of benzofuran derivatives from tyrosol 384
Apoptotic cell signaling in lymphocytes from HIV+ patients during successful therapy 382
Studies on the induction of human lymphocyte apoptosis by prostaglandin-E2 380
(-)-(1R,2R,7S,8aR)-1,2,7-trihydroxyindolizidine ((-)-7S-OH-lentiginosine): Synthesis and proapoptotic activity 380
CD4+ lymphocyte increases in HIV patients during potent antiretroviral therapy are dependent on inhibition of CD8+ cell apoptosis 378
Antiviral activity of seed extract from Citrus bergamia towards human retroviruses 378
Enantiomerically pure phosphonated carbocyclic 2'-oxa-3'-azanucleosides: synthesis and biological evaluation 376
Truncated reverse isoxazolidinyl nucleosides: a new class of allosteric HIV-1 reverse transcriptase inhibitors 375
Biomolecular Fishing for Calixarene Partners by a Chemoproteomic Approach 374
Synthesis and biological evaluation of styrylheterocycles analogs of resveratrol as apoptosis-inducing agents 371
Aspects of IgE regulation in normal and atopic individuals 369
HSV-1-induced activation of NF-κB protects U937 monocytic cells against both virus replication and apoptosis 367
Effect of beta interferon on HTLV I infection of fractionated T cells 365
Characteristics of the infection of rat astroglia and macrophages by HTLV-I. 365
Lamivudine resistance in human T-cell leukemia virus type 1 may be due to a polymorphism at codon 118 (V→i) of the reverse transcriptase (multiple letters) 364
Biological aspects of HIV infection. 363
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine 363
Protective effect of the acyclic nucleoside phosphonate tenofovir toward human T-cell leukemia/lymphotropic virus type 1 infection of human peripheral blood mononuclear cells in vitro 359
Truncated phosphonated C-1'-branched N,O-nucleosides: A new class of antiviral agents 359
Increased caspase activation in peripheral blood mononuclear cells of patients with Alzheimer’s disease 357
A novel, cell-free PCR-based assay for evaluating the inhibitory activity of antiretroviral compounds towards HIV reverse transcriptase 356
Inhibition of cell-to-cell transmission of human T-cell lymphotropic virus type 1 in vitro by carbohydrate-binding agents 356
Apoptosis-associated gene expression in HIV-infected patients in response to successful antiretroviral therapy 355
Modulation of Apoptosis During HTLV-1-Mediated Immortalization Process In Vitro 355
Reducing the global burden of HTLV-1 infection: An agenda for research and action 353
Installing tungsten Fischer carbene complexes into a calixarene framework 353
Susceptibility of lymphoma cells bearing human T leukemia/lymphoma virus (HTLV) to NK-mediated cytolysis 352
HBV and HIV expression in lymph nodes of HIV positive LAS patients: histology and in situ hybridization 350
Susceptibility of Primary HTLV-1 Isolates from Patients with HTLV-1-Associated Myelopathy to Reverse Transcriptase Inhibitors 350
HIV genome in peripheral blood mononuclear cells of seronegative regular sexual partners of HIV-infected subjects 348
Phosphonated Carbocyclic 2'-Oxa-3'-azanucleosides as New Antiretroviral Agents 346
Effector caspase activation, in the absence of a conspicuous apoptosis induction, in mononuclear cells treated with azidothymidine 346
Development and evaluation of a simple and effective RT-qPCR inhibitory assay for detection of the efficacy of compounds towards HIV reverse transcriptase 345
Role of inflammation and apoptosis in multiple sclerosis: Comparative analysis between the periphery and the central nervous system 344
N,O-Nucleosides from Ene Reaction of (Nitrosocarbonyl)mesitylene with Crotyl Alcohol: Selectivity, Scope, and Limitations 342
Effects of nucleoside-based antiretroviral chemotherapy on human T cell leukaemia/lymphotropic virus type 1 (HTLV-1) infection in vitro 341
Transient HTLV-I infection of a human glioma cell line following cell-free exposure 340
Mononuclear cells from peripheral blood of adult donors and from cord blood are equally protected by alpha- and beta-interferons against infection with HTLV-I 339
Synthesis of biotin and fluorescein labeled (–)-lentiginosine. 339
Demonstration of HIV viral sequences in seronegative at risk individuale by in situ hybridization and polymerase chain reaction 338
Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB. 337
Effect of lamivudine on transmission of human T-cell lymphotropic virus type 1 to adult peripheral blood mononuclear cells in vitro 334
Screening transplant donors for HTLV-1 and -2 327
Biologic and molecular characterization of producer and nonproducer clones from HUT-78 cells infected with a patient HIV isolate 322
Quantification of HTLV-1 reverse transcriptase activity in ATL patients treated with zidovudine and interferon-alpha 307
Dysregulated NF-κB Pathway in Peripheral Mononuclear Cells of Alzheimer's Disease Patients. 297
Determination of Intracellular p 19 core protein in HTLV I infected cells by flow microcytometry analysis 290
PROTECTIVE EFFECT OF INTERFERON-BETA ON HUMAN T-CELL LEUKEMIA-VIRUS TYPE-I INFECTION OF CD4+ T-CELLS ISOLATED FROM HUMAN CORD-BLOOD 282
Ene Reaction of Nitrosocarbonyl Mesitylene with the Cinnamyl Alcohol: Metabolic Activity and Apoptosis of the Synthetized 6-Chloropurine N,O-Nucleoside Analogues 274
NF-κB-Dependent Production of ROS and Restriction of HSV-1 Infection in U937 Monocytic Cells 266
Aspects of IgE regulation in normal and atopic individuals 256
Synthesis of potential HIV integrase inhibitors inspired by natural polyphenol structures 255
Focus on recently developed assays for detection of resistance/sensitivity to reverse transcriptase inhibitors 253
Future perspectives on drug targeting in adult T cell leukemia-lymphoma 238
Pyrimidine 2,4-Diones in the design of new HIV RT inhibitors 223
Inhibition of IκBα phosphorylation potentiates regulated cell death induced by azidothymidine in HTLV-1 infected cells 160
Antiretroviral therapy in HTLV-1 infection: an updated overview 106
Appraisal of a Simple and Effective RT-qPCR Assay for Evaluating the Reverse Transcriptase Activity in Blood Samples from HIV-1 Patients 96
N,O-Nucleoside analogues: metabolic and apoptotic activity 67
Biological Evaluation of Triorganotin Derivatives as Potential Anticancer Agents 39
Quantitative Evaluation of Very Low Levels of HIV-1 Reverse Transcriptase by a Novel Highly Sensitive RT-qPCR Assay 36
Caspase-8 is required for HSV-1-induced apoptosis and promotes effective viral particle release via autophagy inhibition 30
Inhibition of the RNA-dependent RNA-polymerase from SARS-CoV-2 by 6-chloropurine isoxazoline-carbocyclic monophosphate nucleotides 18
Stereocontrolled synthesis of new iminosugar lipophilic derivatives and evaluation of biological activities 13
Totale 34.205
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Categoria #
all - tutte 65.037
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 65.037
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20207.040 0 0 0 830 790 1.056 825 826 787 711 577 638
2020/20215.354 536 702 558 719 565 504 725 519 136 100 192 98
2021/20221.089 64 149 61 62 24 97 68 24 73 121 70 276
2022/20231.369 150 84 48 186 128 309 101 98 106 2 118 39
2023/2024444 70 12 28 20 70 106 20 17 6 9 9 77
2024/2025840 86 472 212 70 0 0 0 0 0 0 0 0
Totale 34.250