A convenient strategy for the preparation of compounds bearing the benzofuran skeleton starting from tyrosol, a phenol largely present in olive oil production waste, with no biological importance, is reported. A bromination/methoxylation sequence, already described for the synthetic transformation of naturally occurring compounds, was exploited. Depending on the solvent used for the methoxylation reaction together with the presence of a 4-phenol moiety respect to the side chain, benzodihydrofurans or a benzofurans derivative can be obtained.
Bovicelli, P., Bottaro, F., Sappino, C., Tomei, M., Nardi, V., Proietti Silvestri, I., et al. (2016). Simple and efficient synthesis of benzofuran derivatives from tyrosol. SYNTHETIC COMMUNICATIONS, 46(3), 242-248 [10.1080/00397911.2015.1133828].
Tipologia: | Articolo su rivista | |
Citazione: | Bovicelli, P., Bottaro, F., Sappino, C., Tomei, M., Nardi, V., Proietti Silvestri, I., et al. (2016). Simple and efficient synthesis of benzofuran derivatives from tyrosol. SYNTHETIC COMMUNICATIONS, 46(3), 242-248 [10.1080/00397911.2015.1133828]. | |
URL: | www.tandf.co.uk/journals/titles/00397911.asp | |
IF: | Con Impact Factor ISI | |
Lingua: | English | |
Settore Scientifico Disciplinare: | Settore CHIM/03 - Chimica Generale e Inorganica Settore BIO/14 | |
Revisione (peer review): | Esperti anonimi | |
Tipo: | Articolo | |
Rilevanza: | Rilevanza internazionale | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1080/00397911.2015.1133828 | |
Stato di pubblicazione: | Pubblicato | |
Data di pubblicazione: | 2016 | |
Titolo: | Simple and efficient synthesis of benzofuran derivatives from tyrosol | |
Autori: | ||
Autori: | Bovicelli, P; Bottaro, F; Sappino, C; Tomei, M; Nardi, V; Proietti Silvestri, I; Macchi, B; Frezza, C; Righi, G | |
Appare nelle tipologie: | 01 - Articolo su rivista |
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BovicelliBenzofuranSintheticComunications2016electronic versio.pdf | Articolo | N/A | Copyright dell'editore | Open Access Visualizza/Apri |