IRIS
ROTILIO, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 54.059
EU - Europa 5.876
AS - Asia 3.790
SA - Sud America 773
AF - Africa 60
Continente sconosciuto - Info sul continente non disponibili 28
OC - Oceania 9
Totale 64.595
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Nazione #
US - Stati Uniti d'America 53.939
SG - Singapore 1.849
PL - Polonia 1.277
DE - Germania 956
FR - Francia 877
CN - Cina 839
UA - Ucraina 762
BR - Brasile 658
HK - Hong Kong 475
IE - Irlanda 465
SE - Svezia 355
GB - Regno Unito 293
RU - Federazione Russa 283
IT - Italia 254
FI - Finlandia 177
KR - Corea 177
VN - Vietnam 148
CA - Canada 80
IN - India 56
BE - Belgio 53
JP - Giappone 46
ID - Indonesia 39
AR - Argentina 38
BD - Bangladesh 28
MX - Messico 27
EU - Europa 26
TR - Turchia 22
ZA - Sudafrica 22
ES - Italia 20
IQ - Iraq 20
NL - Olanda 20
AT - Austria 19
EC - Ecuador 19
UZ - Uzbekistan 15
PK - Pakistan 14
VE - Venezuela 14
CL - Cile 11
KE - Kenya 11
CO - Colombia 10
CZ - Repubblica Ceca 10
LT - Lituania 9
MA - Marocco 9
CH - Svizzera 8
PY - Paraguay 8
SA - Arabia Saudita 8
AU - Australia 7
EG - Egitto 7
IL - Israele 7
KG - Kirghizistan 6
RO - Romania 6
DK - Danimarca 5
MY - Malesia 5
UY - Uruguay 5
AE - Emirati Arabi Uniti 4
BO - Bolivia 4
KH - Cambogia 4
NP - Nepal 4
PH - Filippine 4
RS - Serbia 4
BY - Bielorussia 3
GR - Grecia 3
GY - Guiana 3
HU - Ungheria 3
JM - Giamaica 3
JO - Giordania 3
KZ - Kazakistan 3
PE - Perù 3
TH - Thailandia 3
TN - Tunisia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AL - Albania 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
DM - Dominica 2
DZ - Algeria 2
ET - Etiopia 2
HN - Honduras 2
IR - Iran 2
KI - Kiribati 2
LK - Sri Lanka 2
NI - Nicaragua 2
OM - Oman 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
CG - Congo 1
CU - Cuba 1
DO - Repubblica Dominicana 1
GH - Ghana 1
KW - Kuwait 1
LB - Libano 1
MD - Moldavia 1
MK - Macedonia 1
MT - Malta 1
NG - Nigeria 1
NO - Norvegia 1
PT - Portogallo 1
SI - Slovenia 1
Totale 64.594
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Città #
Woodbridge 16.490
Wilmington 13.849
Houston 12.767
Fairfield 1.473
Ann Arbor 1.376
Kraków 1.251
Ashburn 915
Singapore 844
Chandler 843
Jacksonville 713
Seattle 613
Cambridge 519
Hong Kong 475
Dublin 439
Beijing 416
Medford 366
Dearborn 311
New York 199
Santa Clara 193
The Dalles 176
Lawrence 172
Los Angeles 138
Mülheim 127
Menlo Park 104
Council Bluffs 101
San Diego 88
Buffalo 87
Dallas 71
Boardman 66
Zhengzhou 66
Munich 57
Rome 57
São Paulo 56
Falls Church 54
Brussels 53
Moscow 43
Milan 42
Mountain View 41
University Park 40
Ho Chi Minh City 38
Toronto 38
San Mateo 37
London 35
Guangzhou 34
Phoenix 33
Rio de Janeiro 32
Detroit 31
Hanoi 31
Norwalk 31
Daejeon 27
Jakarta 27
Redondo Beach 26
Verona 26
Warsaw 24
Helsinki 23
Redwood City 23
Columbus 21
Hefei 21
Montreal 21
Brooklyn 20
Nürnberg 20
Orem 20
Shanghai 20
Chicago 19
Dong Ket 19
Tokyo 19
Saint Petersburg 18
San Jose 18
Belo Horizonte 15
Palo Alto 15
Johannesburg 14
Kunming 14
Nuremberg 14
San Francisco 14
Chennai 13
Denver 13
Jinan 13
Stockholm 13
Baghdad 12
Nanjing 12
Boston 11
Indiana 11
Porto Alegre 11
Ankara 10
Brasília 10
Indianapolis 10
Washington 10
Auburn Hills 9
Brno 9
Creede 9
Guayaquil 9
Hebei 9
Manchester 9
Poplar 9
Fortaleza 8
Frankfurt am Main 8
Nairobi 8
Ribeirão Preto 8
Tappahannock 8
Mexico City 7
Totale 56.788
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Nome #
A histidine-rich metal binding domain at the N terminus of Cu,Zn-superoxide dismutases from pathogenic bacteria 615
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 512
Low-Shear Modeled Microgravity Enhances Salmonella Enterica Resistance to Hydrogen Peroxide Through a Mechanism Involving KatG and KatN 512
Pro-apoptotic activity of novel isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage 508
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 506
Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells 496
Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS 493
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2 488
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis 488
Imbalance in corneal redox state during herpes simplex virus 1-induced keratitis in rabbits. Effectiveness of exogenous glutathione supply 484
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 483
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 482
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 481
Increased expression of periplasmic Cu,Zn superoxide dismutase enhances survival of Escherichia coli invasive strains within nonphagocytic cells 478
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 478
Toward the engineering of a super efficient enzyme 473
Isatin-Schiff base copper(II) complexes and their influence on cellular viability 473
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis 471
Regulation of CU, ZNSOD by metals in S-Cereivisiae and Zea-Mays 470
Rescue of cells from apoptosis by inhibition of active GSH extrusion 469
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 468
Activation and induction by copper of Cu/Zn superoxide dismutase in Saccharomyces cerevisiae. Presence of an inactive proenzyme in anaerobic yeast 467
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of AMP-activated protein kinase/p38MAPK/p53 signalling axis Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment 466
Intracellular GSH content and HIV replication in human macrophages 463
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals 463
Distinctive functional features in prokaryotic and eukaryotic Cu,Zn superoxide dismutases 462
Developmental expression of Cu,Zn superoxide dismutase in Xenopus. Constant level of the enzyme in oogenesis and embryogenesis 461
Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice 459
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 457
Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: electrophysiologic changes and ascorbyl radical formation 457
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence 457
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 455
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 455
Non-oxidative loss of glutathione in apoptosis via GSH extrusion 455
Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase 452
Transduction of reducing power across the plasma membrane by reduced glutathione. A 1H-NMR spin-echo study of intact human erythrocytes 451
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis 451
A study of the dual role of copper in superoxide dismutase as antioxidant and pro-oxidant in cellular models of amyotrophic lateral sclerosis 450
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 448
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 448
The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis. 447
Xenopus laevis Cu,Zn superoxide dismutase B cDNA sequence 443
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells 441
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration 440
Correlation between superoxide dismutase, glutathione peroxidase and catalase in isolated rat hepatocytes during fetal development. 440
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 440
Benefits from dietary polyphenols for brain aging and Alzheimer's disease 439
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site 439
Purification and characterization of Ag,Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver 439
Role of zinc-coordination and of the glutathione redox couple in the redox susceptibility of human transcription factor Sp1 439
Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells 438
Superoxide dismutase 1 modulates expression of transferrin receptor 438
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. 437
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 435
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 435
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells 434
Role of the electrostatic loop of Cu,Zn superoxide dismutase in the copper uptake process 433
Voltage-activated sodium currents in a cell line expressing a Cu,Zn superoxide dismutase typical of familial ALS 432
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 430
Thermal stability and redox properties of M. tuberculosis CuSOD 429
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis 428
Copper-dependent oxidative stress and neurodegeneration 428
Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in Neurodegenerative processes 427
Evidence for co-regulation of Cu,Zn superoxide dismutase and metallothionein gene expression in yeast through transcriptional control by copper via the ACE 1 factor 426
Temperature-dependent protein folding in vivo--lower growth temperature increases yield of two genetic variants of Xenopus laevis Cu,Zn superoxide dismutase in Escherichia coli 425
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 424
Crystallographic characterization and three-dimensional model of yeast Cu,Zn superoxide dismutase 424
trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways 424
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 423
In vivo formation of Cu,Zn superoxide dismutase disulfide bond in Escherichia coli 422
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: A rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 422
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. 421
Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients 420
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials 420
Crystal structure solution and refinement of the semisynthetic cobalt -substituted bovine erythrocyte superoxide dismutase at 2.0Å resolution 420
Molecular modelling and electrostatic potential calculations on chemically modified Cu,Zn superoxide dismutases from Bos taurus and the shark Prionace glauca 420
Copper-dependent toxicity in SH-SY5Y neuroblasoma cells involves mitochondrial damage. 419
Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells 418
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase 417
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS 416
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression 415
Primary structure from amino acid and cDNA sequences of two Cu,Zn superoxide dismutase variants from Xenopus laevis 414
Redox bases underlying the anti-tumor activity of garlic-contained organo-sulfur compounds: Implication in chemoprevention and chemotherapy 414
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. 413
Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways 412
Purification of iron superoxide dismutase from the cyanobacterium Anabaena cylindrica Lemm. and localization of the enzyme in heterocystsis by immunonogold labeling 412
Differential binding of anions to the active site of Cu,Zn superoxide dismutase. A study of the Co,Zn enzyme derivative 410
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis 409
Antiapoptotic response to induced GSH depletion: Involvement of heat shock proteins and NF-kappa B activation 408
Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells 406
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells 405
Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis 402
Under the ROS…thiol network is the principal suspect for autophagy commitment. 400
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase 399
A free cysteine residue at the dimer interface decreases conformational stability of Xenopus laevis copper,zinc superoxide dismutase 399
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection 398
Neuronal nitric oxide synthase protects neuroblastoma cells from oxidative stress mediated by garlic derivatives 396
p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance 396
p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration. 395
Prolonged copper depletion induces expression of antioxidants and triggers apoptosis in SH-SY5Y neuroblastoma cells 393
Totale 44.293
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Categoria #
all - tutte 134.659
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 134.659
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20213.762 0 0 0 0 0 873 1.220 825 207 167 328 142
2021/20221.947 65 168 117 118 79 187 90 74 288 128 89 544
2022/20232.278 225 134 38 347 228 518 165 161 214 12 192 44
2023/2024710 108 18 50 25 92 217 13 51 12 14 11 99
2024/20253.567 148 803 354 209 133 284 291 225 311 305 257 247
2025/20262.637 434 307 671 521 506 198 0 0 0 0 0 0
Totale 64.930