IRIS
ROTILIO, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 52.762
EU - Europa 5.574
AS - Asia 1.594
Continente sconosciuto - Info sul continente non disponibili 28
SA - Sud America 25
OC - Oceania 7
AF - Africa 2
Totale 59.992
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Nazione #
US - Stati Uniti d'America 52.721
PL - Polonia 1.253
DE - Germania 907
FR - Francia 867
SG - Singapore 831
UA - Ucraina 752
CN - Cina 465
IE - Irlanda 463
SE - Svezia 340
RU - Federazione Russa 265
GB - Regno Unito 228
IT - Italia 218
KR - Corea 174
FI - Finlandia 172
BE - Belgio 47
CA - Canada 37
JP - Giappone 28
EU - Europa 26
IN - India 23
VN - Vietnam 23
BR - Brasile 16
NL - Olanda 13
AT - Austria 11
CZ - Repubblica Ceca 9
UZ - Uzbekistan 9
AU - Australia 7
CH - Svizzera 7
IL - Israele 6
DK - Danimarca 5
IQ - Iraq 5
KG - Kirghizistan 5
RO - Romania 5
CL - Cile 4
KH - Cambogia 4
ES - Italia 3
GR - Grecia 3
ID - Indonesia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AR - Argentina 2
BD - Bangladesh 2
BO - Bolivia 2
ET - Etiopia 2
HK - Hong Kong 2
HU - Ungheria 2
LK - Sri Lanka 2
MX - Messico 2
MY - Malesia 2
PK - Pakistan 2
TR - Turchia 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
AZ - Azerbaigian 1
BG - Bulgaria 1
CU - Cuba 1
DM - Dominica 1
EC - Ecuador 1
IR - Iran 1
KZ - Kazakistan 1
MD - Moldavia 1
NO - Norvegia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 59.992
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Città #
Woodbridge 16.490
Wilmington 13.849
Houston 12.760
Fairfield 1.473
Ann Arbor 1.376
Kraków 1.251
Chandler 843
Ashburn 786
Jacksonville 713
Singapore 702
Seattle 608
Cambridge 519
Dublin 437
Medford 366
Dearborn 311
Beijing 221
Santa Clara 173
Lawrence 172
New York 159
Mülheim 127
Menlo Park 104
San Diego 88
Boardman 66
Zhengzhou 64
Falls Church 54
Brussels 47
Rome 47
Moscow 41
Mountain View 41
University Park 40
Milan 37
San Mateo 37
Munich 33
Toronto 32
Norwalk 31
Detroit 30
Daejeon 27
Verona 26
Helsinki 23
Redwood City 23
Hefei 21
London 21
Phoenix 21
Nürnberg 20
Dong Ket 19
Los Angeles 19
Saint Petersburg 18
Guangzhou 17
Shanghai 17
Palo Alto 15
Kunming 14
Jinan 12
Indiana 11
Nanjing 11
Auburn Hills 9
Brno 9
Creede 9
Hebei 9
Washington 9
São Paulo 8
Tappahannock 8
Hounslow 6
Pune 6
San Francisco 6
Shenyang 6
Fuzhou 5
Hangzhou 5
Kilburn 5
Kurokami 5
Leawood 5
Nuremberg 5
Yellow Springs 5
Baghdad 4
Del Norte 4
Delhi 4
Enterprise 4
Las Vegas 4
Lausanne 4
Phnom Penh 4
Portland 4
Prescot 4
Redmond 4
Saint Paul 4
Vienna 4
Wuhan 4
Chicago 3
Chongqing 3
Clearwater 3
Council Bluffs 3
Frascati 3
Groningen 3
Guiyang 3
Hanoi 3
Islington 3
Kemerovo 3
Mcallen 3
Monmouth Junction 3
Nanchang 3
Rio de Janeiro 3
San Jose 3
Totale 54.680
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Nome #
A histidine-rich metal binding domain at the N terminus of Cu,Zn-superoxide dismutases from pathogenic bacteria 563
Pro-apoptotic activity of novel isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage 482
Low-Shear Modeled Microgravity Enhances Salmonella Enterica Resistance to Hydrogen Peroxide Through a Mechanism Involving KatG and KatN 481
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 477
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 474
Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS 467
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 461
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis 460
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis 459
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2 454
Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells 454
Regulation of CU, ZNSOD by metals in S-Cereivisiae and Zea-Mays 453
Increased expression of periplasmic Cu,Zn superoxide dismutase enhances survival of Escherichia coli invasive strains within nonphagocytic cells 447
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 445
Toward the engineering of a super efficient enzyme 444
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 444
Intracellular GSH content and HIV replication in human macrophages 443
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 442
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of AMP-activated protein kinase/p38MAPK/p53 signalling axis Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment 439
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 439
Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase 439
Imbalance in corneal redox state during herpes simplex virus 1-induced keratitis in rabbits. Effectiveness of exogenous glutathione supply 439
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals 437
Transduction of reducing power across the plasma membrane by reduced glutathione. A 1H-NMR spin-echo study of intact human erythrocytes 436
Developmental expression of Cu,Zn superoxide dismutase in Xenopus. Constant level of the enzyme in oogenesis and embryogenesis 436
Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: electrophysiologic changes and ascorbyl radical formation 435
Isatin-Schiff base copper(II) complexes and their influence on cellular viability 434
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 434
Rescue of cells from apoptosis by inhibition of active GSH extrusion 433
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 429
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 428
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 426
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis 424
Distinctive functional features in prokaryotic and eukaryotic Cu,Zn superoxide dismutases 422
A study of the dual role of copper in superoxide dismutase as antioxidant and pro-oxidant in cellular models of amyotrophic lateral sclerosis 422
Non-oxidative loss of glutathione in apoptosis via GSH extrusion 421
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 420
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence 420
The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis. 419
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. 418
Correlation between superoxide dismutase, glutathione peroxidase and catalase in isolated rat hepatocytes during fetal development. 417
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 417
Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice 415
Xenopus laevis Cu,Zn superoxide dismutase B cDNA sequence 415
Activation and induction by copper of Cu/Zn superoxide dismutase in Saccharomyces cerevisiae. Presence of an inactive proenzyme in anaerobic yeast 414
Role of zinc-coordination and of the glutathione redox couple in the redox susceptibility of human transcription factor Sp1 414
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 414
Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells 412
Crystallographic characterization and three-dimensional model of yeast Cu,Zn superoxide dismutase 412
Superoxide dismutase 1 modulates expression of transferrin receptor 411
Purification and characterization of Ag,Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver 409
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis 408
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells 408
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 406
Voltage-activated sodium currents in a cell line expressing a Cu,Zn superoxide dismutase typical of familial ALS 406
trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways 406
Role of the electrostatic loop of Cu,Zn superoxide dismutase in the copper uptake process 405
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. 404
Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in Neurodegenerative processes 404
Crystal structure solution and refinement of the semisynthetic cobalt -substituted bovine erythrocyte superoxide dismutase at 2.0Å resolution 404
Benefits from dietary polyphenols for brain aging and Alzheimer's disease 401
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration 401
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 399
Thermal stability and redox properties of M. tuberculosis CuSOD 399
Molecular modelling and electrostatic potential calculations on chemically modified Cu,Zn superoxide dismutases from Bos taurus and the shark Prionace glauca 399
Primary structure from amino acid and cDNA sequences of two Cu,Zn superoxide dismutase variants from Xenopus laevis 398
Purification of iron superoxide dismutase from the cyanobacterium Anabaena cylindrica Lemm. and localization of the enzyme in heterocystsis by immunonogold labeling 397
Temperature-dependent protein folding in vivo--lower growth temperature increases yield of two genetic variants of Xenopus laevis Cu,Zn superoxide dismutase in Escherichia coli 397
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS 396
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: A rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 396
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 396
Evidence for co-regulation of Cu,Zn superoxide dismutase and metallothionein gene expression in yeast through transcriptional control by copper via the ACE 1 factor 396
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression 395
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 393
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. 392
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells 391
Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells 391
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site 391
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis 390
Copper-dependent oxidative stress and neurodegeneration 390
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials 387
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells 386
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase 386
Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients 385
Copper-dependent toxicity in SH-SY5Y neuroblasoma cells involves mitochondrial damage. 385
Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells 384
In vivo formation of Cu,Zn superoxide dismutase disulfide bond in Escherichia coli 382
Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways 382
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase 380
Neuronal nitric oxide synthase protects neuroblastoma cells from oxidative stress mediated by garlic derivatives 379
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection 377
Differential binding of anions to the active site of Cu,Zn superoxide dismutase. A study of the Co,Zn enzyme derivative 376
p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration. 371
Conserved enzyme-substrate electrostatic attraction in prokariotic Cu,Zn superoxide dismutases 371
Conservation of local electric fields in the evolution of Cu,Zn superoxide dismutase 371
Reconstitution of Cu,Zn-superoxide dismutase by the Cu(I).glutathione complex 370
Increase of Cu,Zn-superoxide dismutase activity during differentiation of human K562 cells involves activation by copper of a constantly expressed copper-deficient protein 369
Under the ROS…thiol network is the principal suspect for autophagy commitment. 369
Prolonged copper depletion induces expression of antioxidants and triggers apoptosis in SH-SY5Y neuroblastoma cells 369
Modelling the three-dimensional structure and electrostatic potential field of the two Cu,Zn superoxide dismutase variants from Xenopus laevis 369
Totale 41.457
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Categoria #
all - tutte 110.480
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 110.480
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202010.318 0 0 0 0 1.227 1.594 1.352 1.434 1.377 1.257 954 1.123
2020/20218.894 959 1.089 970 1.212 902 873 1.220 825 207 167 328 142
2021/20221.947 65 168 117 118 79 187 90 74 288 128 89 544
2022/20232.278 225 134 38 347 228 518 165 161 214 12 192 44
2023/2024710 108 18 50 25 92 217 13 51 12 14 11 99
2024/20251.601 148 803 354 209 87 0 0 0 0 0 0 0
Totale 60.327