ROTILIO, GIUSEPPE
 Distribuzione geografica
Continente #
NA - Nord America 57.828
EU - Europa 6.706
AS - Asia 5.078
SA - Sud America 896
Continente sconosciuto - Info sul continente non disponibili 363
AF - Africa 85
OC - Oceania 12
Totale 70.968
Nazione #
US - Stati Uniti d'America 57.541
SG - Singapore 2.338
PL - Polonia 1.285
CN - Cina 1.024
DE - Germania 1.003
FR - Francia 952
UA - Ucraina 766
BR - Brasile 741
RU - Federazione Russa 593
HK - Hong Kong 506
IE - Irlanda 469
IT - Italia 446
VN - Vietnam 434
SE - Svezia 362
GB - Regno Unito 333
FI - Finlandia 259
KR - Corea 185
CA - Canada 163
BD - Bangladesh 139
JP - Giappone 117
IN - India 78
BE - Belgio 54
ID - Indonesia 49
AR - Argentina 44
MX - Messico 35
NL - Olanda 35
ES - Italia 31
IQ - Iraq 30
EC - Ecuador 27
CR - Costa Rica 26
EU - Europa 26
TR - Turchia 26
ZA - Sudafrica 25
CO - Colombia 22
AT - Austria 21
PK - Pakistan 21
VE - Venezuela 21
PH - Filippine 17
UZ - Uzbekistan 16
MY - Malesia 15
CZ - Repubblica Ceca 14
SA - Arabia Saudita 14
EG - Egitto 13
MA - Marocco 13
CL - Cile 12
HN - Honduras 12
JM - Giamaica 12
KE - Kenya 12
LT - Lituania 11
AU - Australia 10
IL - Israele 10
RO - Romania 10
PY - Paraguay 9
CH - Svizzera 8
TH - Thailandia 8
TT - Trinidad e Tobago 8
DK - Danimarca 7
UY - Uruguay 7
BO - Bolivia 6
KG - Kirghizistan 6
NI - Nicaragua 6
AE - Emirati Arabi Uniti 5
DZ - Algeria 5
EE - Estonia 5
ET - Etiopia 5
GT - Guatemala 5
JO - Giordania 5
KH - Cambogia 5
NP - Nepal 5
SV - El Salvador 5
TN - Tunisia 5
AL - Albania 4
GY - Guiana 4
HU - Ungheria 4
KZ - Kazakistan 4
PT - Portogallo 4
RS - Serbia 4
BG - Bulgaria 3
BY - Bielorussia 3
GR - Grecia 3
KW - Kuwait 3
MT - Malta 3
OM - Oman 3
PE - Perù 3
SI - Slovenia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
DM - Dominica 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GP - Guadalupe 2
IR - Iran 2
KI - Kiribati 2
LB - Libano 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
MK - Macedonia 2
Totale 70.611
Città #
Woodbridge 16.490
Wilmington 13.856
Houston 12.773
Ashburn 1.495
Fairfield 1.473
Ann Arbor 1.376
Singapore 1.258
Kraków 1.251
Chandler 843
San Jose 727
Jacksonville 717
Seattle 619
Cambridge 524
Hong Kong 503
Dublin 441
Beijing 431
Medford 366
Council Bluffs 365
Dearborn 311
New York 280
Santa Clara 267
The Dalles 260
Los Angeles 189
Lawrence 172
Mülheim 127
Ho Chi Minh City 110
Buffalo 107
Helsinki 104
Menlo Park 104
Hanoi 103
San Diego 96
Dallas 87
Tokyo 87
Rome 85
São Paulo 79
Moscow 76
Boardman 69
Zhengzhou 66
Milan 57
Munich 57
Toronto 55
Brussels 54
Falls Church 54
Phoenix 51
Lauterbourg 48
Montreal 41
Mountain View 41
London 40
University Park 40
Chicago 39
San Mateo 37
Guangzhou 35
Rio de Janeiro 35
Detroit 33
Orem 33
Norwalk 32
Atlanta 30
Jakarta 29
Verona 29
Warsaw 29
Brooklyn 27
Daejeon 27
North Charleston 27
Denver 26
Frankfurt am Main 26
Redondo Beach 26
Columbus 25
Redwood City 23
Shanghai 23
Hefei 22
North Bergen 20
Nürnberg 20
San José 20
Dong Ket 19
Carrboro 18
Haiphong 18
Kaiserslautern 18
Saint Petersburg 18
San Francisco 18
Stockholm 18
Baghdad 17
Belo Horizonte 17
Da Nang 17
Johannesburg 16
Philadelphia 16
Reading 16
Amsterdam 15
Nuremberg 15
Palo Alto 15
Brasília 14
Chennai 14
Jinan 14
Kunming 14
Las Vegas 14
Washington 14
Fortaleza 13
Guayaquil 13
Indianapolis 13
Manchester 13
Paris 13
Totale 59.918
Nome #
A histidine-rich metal binding domain at the N terminus of Cu,Zn-superoxide dismutases from pathogenic bacteria 660
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 562
Pro-apoptotic activity of novel isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage 552
Low-Shear Modeled Microgravity Enhances Salmonella Enterica Resistance to Hydrogen Peroxide Through a Mechanism Involving KatG and KatN 540
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 535
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 533
Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells 530
Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS 528
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 528
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2 525
Imbalance in corneal redox state during herpes simplex virus 1-induced keratitis in rabbits. Effectiveness of exogenous glutathione supply 522
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 521
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis 521
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 520
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 519
Increased expression of periplasmic Cu,Zn superoxide dismutase enhances survival of Escherichia coli invasive strains within nonphagocytic cells 511
Superoxide dismutase 1 modulates expression of transferrin receptor 510
Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice 510
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals 509
Toward the engineering of a super efficient enzyme 507
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of AMP-activated protein kinase/p38MAPK/p53 signalling axis Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment 507
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site 507
Activation and induction by copper of Cu/Zn superoxide dismutase in Saccharomyces cerevisiae. Presence of an inactive proenzyme in anaerobic yeast 506
A study of the dual role of copper in superoxide dismutase as antioxidant and pro-oxidant in cellular models of amyotrophic lateral sclerosis 506
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis 506
Isatin-Schiff base copper(II) complexes and their influence on cellular viability 505
Distinctive functional features in prokaryotic and eukaryotic Cu,Zn superoxide dismutases 500
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis 499
Developmental expression of Cu,Zn superoxide dismutase in Xenopus. Constant level of the enzyme in oogenesis and embryogenesis 494
Regulation of CU, ZNSOD by metals in S-Cereivisiae and Zea-Mays 493
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence 493
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 492
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials 491
Intracellular GSH content and HIV replication in human macrophages 490
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 490
Rescue of cells from apoptosis by inhibition of active GSH extrusion 488
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration 486
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 485
Role of the electrostatic loop of Cu,Zn superoxide dismutase in the copper uptake process 485
The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis. 484
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells 481
Transduction of reducing power across the plasma membrane by reduced glutathione. A 1H-NMR spin-echo study of intact human erythrocytes 480
Xenopus laevis Cu,Zn superoxide dismutase B cDNA sequence 480
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells 479
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 479
Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase 479
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 478
Redox bases underlying the anti-tumor activity of garlic-contained organo-sulfur compounds: Implication in chemoprevention and chemotherapy 478
Non-oxidative loss of glutathione in apoptosis via GSH extrusion 478
Copper-dependent oxidative stress and neurodegeneration 477
Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: electrophysiologic changes and ascorbyl radical formation 476
Temperature-dependent protein folding in vivo--lower growth temperature increases yield of two genetic variants of Xenopus laevis Cu,Zn superoxide dismutase in Escherichia coli 476
Voltage-activated sodium currents in a cell line expressing a Cu,Zn superoxide dismutase typical of familial ALS 474
Role of zinc-coordination and of the glutathione redox couple in the redox susceptibility of human transcription factor Sp1 474
In vivo formation of Cu,Zn superoxide dismutase disulfide bond in Escherichia coli 472
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 472
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 471
Purification and characterization of Ag,Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver 471
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 470
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 469
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis 467
Thermal stability and redox properties of M. tuberculosis CuSOD 465
Correlation between superoxide dismutase, glutathione peroxidase and catalase in isolated rat hepatocytes during fetal development. 465
Benefits from dietary polyphenols for brain aging and Alzheimer's disease 464
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. 463
Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells 463
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 461
Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells 460
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 458
trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways 456
Antiapoptotic response to induced GSH depletion: Involvement of heat shock proteins and NF-kappa B activation 454
Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways 454
Evidence for co-regulation of Cu,Zn superoxide dismutase and metallothionein gene expression in yeast through transcriptional control by copper via the ACE 1 factor 453
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: A rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 452
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells 451
Molecular modelling and electrostatic potential calculations on chemically modified Cu,Zn superoxide dismutases from Bos taurus and the shark Prionace glauca 450
Copper-dependent toxicity in SH-SY5Y neuroblasoma cells involves mitochondrial damage. 449
Under the ROS…thiol network is the principal suspect for autophagy commitment. 449
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase 446
Crystallographic characterization and three-dimensional model of yeast Cu,Zn superoxide dismutase 446
Cell signalling and the glutathione redox system 445
A free cysteine residue at the dimer interface decreases conformational stability of Xenopus laevis copper,zinc superoxide dismutase 445
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. 444
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. 444
Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in Neurodegenerative processes 444
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS 443
Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients 443
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis 442
High-affinity Zn2+ uptake system ZnuABC is required for bacterial zinc homeostasis in intracellular environments and contributes to the virulence of Salmonella enterica 442
Primary structure from amino acid and cDNA sequences of two Cu,Zn superoxide dismutase variants from Xenopus laevis 442
Crystal structure solution and refinement of the semisynthetic cobalt -substituted bovine erythrocyte superoxide dismutase at 2.0Å resolution 442
Overexpression of a hydrogen peroxide-resistant periplasmic Cu,Zn superoxide dismutase protects Escherichia coli from macrophage killing 440
p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration. 439
Differential binding of anions to the active site of Cu,Zn superoxide dismutase. A study of the Co,Zn enzyme derivative 437
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression 436
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection 434
Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells 434
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase 434
Role of the dimeric structure in Cu,Zn superoxide dismutase - pH-dependent, reversible denaturation of the monomeric enzyme from Escherichia coli 432
Purification of iron superoxide dismutase from the cyanobacterium Anabaena cylindrica Lemm. and localization of the enzyme in heterocystsis by immunonogold labeling 431
Totale 47.983
Categoria #
all - tutte 154.578
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 154.578


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.597 0 0 0 118 79 187 90 74 288 128 89 544
2022/20232.278 225 134 38 347 228 518 165 161 214 12 192 44
2023/2024710 108 18 50 25 92 217 13 51 12 14 11 99
2024/20253.567 148 803 354 209 133 284 291 225 311 305 257 247
2025/20266.079 434 307 671 521 506 230 661 823 625 782 249 270
2026/20272.596 331 332 1.385 548 0 0 0 0 0 0 0 0
Totale 70.968