IRIS
ROTILIO, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 56.091
EU - Europa 6.625
AS - Asia 5.046
SA - Sud America 848
Continente sconosciuto - Info sul continente non disponibili 363
AF - Africa 84
OC - Oceania 12
Totale 69.069
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Nazione #
US - Stati Uniti d'America 55.890
SG - Singapore 2.338
PL - Polonia 1.285
CN - Cina 1.020
DE - Germania 1.003
FR - Francia 946
UA - Ucraina 766
BR - Brasile 712
RU - Federazione Russa 592
HK - Hong Kong 506
IE - Irlanda 468
VN - Vietnam 431
IT - Italia 401
SE - Svezia 362
GB - Regno Unito 312
FI - Finlandia 259
KR - Corea 184
BD - Bangladesh 133
CA - Canada 123
JP - Giappone 116
IN - India 78
BE - Belgio 53
ID - Indonesia 47
AR - Argentina 42
NL - Olanda 35
MX - Messico 34
ES - Italia 31
IQ - Iraq 30
EU - Europa 26
TR - Turchia 25
ZA - Sudafrica 25
EC - Ecuador 23
AT - Austria 21
PK - Pakistan 20
VE - Venezuela 18
UZ - Uzbekistan 16
PH - Filippine 15
CZ - Repubblica Ceca 14
MY - Malesia 14
CO - Colombia 13
EG - Egitto 13
MA - Marocco 13
CL - Cile 12
KE - Kenya 12
LT - Lituania 11
SA - Arabia Saudita 11
AU - Australia 10
CR - Costa Rica 10
RO - Romania 10
IL - Israele 9
PY - Paraguay 9
CH - Svizzera 8
JM - Giamaica 8
HN - Honduras 7
UY - Uruguay 7
DK - Danimarca 6
KG - Kirghizistan 6
TH - Thailandia 6
AE - Emirati Arabi Uniti 5
BO - Bolivia 5
DZ - Algeria 5
ET - Etiopia 5
JO - Giordania 5
KH - Cambogia 5
NP - Nepal 5
TN - Tunisia 5
AL - Albania 4
GY - Guiana 4
HU - Ungheria 4
KZ - Kazakistan 4
PT - Portogallo 4
RS - Serbia 4
SV - El Salvador 4
TT - Trinidad e Tobago 4
BG - Bulgaria 3
BY - Bielorussia 3
GR - Grecia 3
MT - Malta 3
NI - Nicaragua 3
OM - Oman 3
PE - Perù 3
SI - Slovenia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
DM - Dominica 2
IR - Iran 2
KI - Kiribati 2
KW - Kuwait 2
LB - Libano 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
MK - Macedonia 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
AO - Angola 1
AW - Aruba 1
BF - Burkina Faso 1
Totale 68.723
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Città #
Woodbridge 16.490
Wilmington 13.855
Houston 12.772
Fairfield 1.473
Ann Arbor 1.376
Singapore 1.258
Kraków 1.251
Ashburn 1.110
Chandler 843
Jacksonville 717
Seattle 618
San Jose 564
Cambridge 524
Hong Kong 503
Dublin 441
Beijing 430
Medford 366
Council Bluffs 357
Dearborn 311
New York 275
Santa Clara 256
The Dalles 251
Lawrence 172
Los Angeles 170
Mülheim 127
Ho Chi Minh City 109
Helsinki 104
Menlo Park 104
Buffalo 103
Hanoi 103
San Diego 96
Tokyo 86
Dallas 85
Rome 78
Moscow 76
Boardman 66
Zhengzhou 66
São Paulo 62
Munich 57
Falls Church 54
Brussels 53
Milan 53
Lauterbourg 48
Phoenix 45
Toronto 45
Mountain View 41
London 40
University Park 40
San Mateo 37
Guangzhou 35
Rio de Janeiro 35
Chicago 33
Orem 33
Detroit 32
Norwalk 31
Montreal 30
Jakarta 29
Verona 29
Warsaw 29
Daejeon 27
Frankfurt am Main 26
Redondo Beach 26
Brooklyn 25
Columbus 24
Redwood City 23
Shanghai 23
Denver 22
Hefei 22
Atlanta 20
Nürnberg 20
Dong Ket 19
North Bergen 19
North Charleston 19
Haiphong 18
Kaiserslautern 18
Saint Petersburg 18
Stockholm 18
Baghdad 17
Belo Horizonte 17
Da Nang 17
Johannesburg 16
Reading 16
San Francisco 16
Amsterdam 15
Nuremberg 15
Palo Alto 15
Chennai 14
Jinan 14
Kunming 14
Washington 14
Paris 13
Ankara 12
Fortaleza 12
Indianapolis 12
Manchester 12
Nanjing 12
Porto Alegre 12
Boston 11
Brasília 11
Indiana 11
Totale 59.182
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Nome #
A histidine-rich metal binding domain at the N terminus of Cu,Zn-superoxide dismutases from pathogenic bacteria 654
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 549
Pro-apoptotic activity of novel isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage 542
Low-Shear Modeled Microgravity Enhances Salmonella Enterica Resistance to Hydrogen Peroxide Through a Mechanism Involving KatG and KatN 532
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 523
Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells 522
Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS 521
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis 512
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 510
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2 509
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 509
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 507
Imbalance in corneal redox state during herpes simplex virus 1-induced keratitis in rabbits. Effectiveness of exogenous glutathione supply 507
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 507
Increased expression of periplasmic Cu,Zn superoxide dismutase enhances survival of Escherichia coli invasive strains within nonphagocytic cells 505
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 504
Superoxide dismutase 1 modulates expression of transferrin receptor 501
Toward the engineering of a super efficient enzyme 498
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site 497
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of AMP-activated protein kinase/p38MAPK/p53 signalling axis Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment 495
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis 493
Isatin-Schiff base copper(II) complexes and their influence on cellular viability 493
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis 493
Distinctive functional features in prokaryotic and eukaryotic Cu,Zn superoxide dismutases 492
Activation and induction by copper of Cu/Zn superoxide dismutase in Saccharomyces cerevisiae. Presence of an inactive proenzyme in anaerobic yeast 491
Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice 491
A study of the dual role of copper in superoxide dismutase as antioxidant and pro-oxidant in cellular models of amyotrophic lateral sclerosis 489
Regulation of CU, ZNSOD by metals in S-Cereivisiae and Zea-Mays 486
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals 485
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence 484
Intracellular GSH content and HIV replication in human macrophages 483
Developmental expression of Cu,Zn superoxide dismutase in Xenopus. Constant level of the enzyme in oogenesis and embryogenesis 481
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 480
Rescue of cells from apoptosis by inhibition of active GSH extrusion 479
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 478
The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis. 478
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells 473
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 472
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 472
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials 472
Non-oxidative loss of glutathione in apoptosis via GSH extrusion 472
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 470
Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase 470
Transduction of reducing power across the plasma membrane by reduced glutathione. A 1H-NMR spin-echo study of intact human erythrocytes 469
Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: electrophysiologic changes and ascorbyl radical formation 469
Xenopus laevis Cu,Zn superoxide dismutase B cDNA sequence 469
Redox bases underlying the anti-tumor activity of garlic-contained organo-sulfur compounds: Implication in chemoprevention and chemotherapy 468
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells 466
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration 466
Role of zinc-coordination and of the glutathione redox couple in the redox susceptibility of human transcription factor Sp1 465
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 465
Role of the electrostatic loop of Cu,Zn superoxide dismutase in the copper uptake process 464
Copper-dependent oxidative stress and neurodegeneration 464
Purification and characterization of Ag,Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver 463
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 459
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 459
Benefits from dietary polyphenols for brain aging and Alzheimer's disease 458
Voltage-activated sodium currents in a cell line expressing a Cu,Zn superoxide dismutase typical of familial ALS 458
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 458
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis 457
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 457
In vivo formation of Cu,Zn superoxide dismutase disulfide bond in Escherichia coli 456
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. 456
Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells 454
Thermal stability and redox properties of M. tuberculosis CuSOD 454
Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells 454
Correlation between superoxide dismutase, glutathione peroxidase and catalase in isolated rat hepatocytes during fetal development. 453
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 451
Temperature-dependent protein folding in vivo--lower growth temperature increases yield of two genetic variants of Xenopus laevis Cu,Zn superoxide dismutase in Escherichia coli 449
trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways 447
Evidence for co-regulation of Cu,Zn superoxide dismutase and metallothionein gene expression in yeast through transcriptional control by copper via the ACE 1 factor 445
Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways 444
Molecular modelling and electrostatic potential calculations on chemically modified Cu,Zn superoxide dismutases from Bos taurus and the shark Prionace glauca 444
Crystallographic characterization and three-dimensional model of yeast Cu,Zn superoxide dismutase 442
Antiapoptotic response to induced GSH depletion: Involvement of heat shock proteins and NF-kappa B activation 441
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: A rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 441
Under the ROS…thiol network is the principal suspect for autophagy commitment. 441
Copper-dependent toxicity in SH-SY5Y neuroblasoma cells involves mitochondrial damage. 440
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. 439
Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in Neurodegenerative processes 438
Cell signalling and the glutathione redox system 437
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase 437
Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients 434
Crystal structure solution and refinement of the semisynthetic cobalt -substituted bovine erythrocyte superoxide dismutase at 2.0Å resolution 434
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells 433
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. 432
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS 432
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis 431
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression 430
High-affinity Zn2+ uptake system ZnuABC is required for bacterial zinc homeostasis in intracellular environments and contributes to the virulence of Salmonella enterica 430
Primary structure from amino acid and cDNA sequences of two Cu,Zn superoxide dismutase variants from Xenopus laevis 430
A free cysteine residue at the dimer interface decreases conformational stability of Xenopus laevis copper,zinc superoxide dismutase 430
Overexpression of a hydrogen peroxide-resistant periplasmic Cu,Zn superoxide dismutase protects Escherichia coli from macrophage killing 429
Differential binding of anions to the active site of Cu,Zn superoxide dismutase. A study of the Co,Zn enzyme derivative 427
Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells 427
p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration. 426
Purification of iron superoxide dismutase from the cyanobacterium Anabaena cylindrica Lemm. and localization of the enzyme in heterocystsis by immunonogold labeling 424
Role of the dimeric structure in Cu,Zn superoxide dismutase - pH-dependent, reversible denaturation of the monomeric enzyme from Escherichia coli 422
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection 418
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase 418
Totale 46.885
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Categoria #
all - tutte 150.203
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 150.203
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.714 0 0 117 118 79 187 90 74 288 128 89 544
2022/20232.278 225 134 38 347 228 518 165 161 214 12 192 44
2023/2024710 108 18 50 25 92 217 13 51 12 14 11 99
2024/20253.567 148 803 354 209 133 284 291 225 311 305 257 247
2025/20266.079 434 307 671 521 506 230 661 823 625 782 249 270
2026/2027697 331 332 34 0 0 0 0 0 0 0 0 0
Totale 69.069