IRIS
ROTILIO, GIUSEPPE
 Distribuzione geografica
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Continente #
NA - Nord America 55.192
EU - Europa 6.516
AS - Asia 4.886
SA - Sud America 836
AF - Africa 82
Continente sconosciuto - Info sul continente non disponibili 28
OC - Oceania 12
Totale 67.552
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Nazione #
US - Stati Uniti d'America 55.039
SG - Singapore 2.330
PL - Polonia 1.283
DE - Germania 1.003
CN - Cina 980
FR - Francia 945
UA - Ucraina 766
BR - Brasile 704
RU - Federazione Russa 592
HK - Hong Kong 503
IE - Irlanda 468
VN - Vietnam 426
SE - Svezia 361
GB - Regno Unito 312
IT - Italia 305
FI - Finlandia 259
KR - Corea 184
JP - Giappone 115
CA - Canada 103
IN - India 78
BE - Belgio 53
ID - Indonesia 44
AR - Argentina 42
BD - Bangladesh 41
NL - Olanda 34
MX - Messico 32
IQ - Iraq 30
ES - Italia 26
EU - Europa 26
ZA - Sudafrica 25
TR - Turchia 23
EC - Ecuador 22
AT - Austria 21
PK - Pakistan 20
VE - Venezuela 17
UZ - Uzbekistan 16
PH - Filippine 14
CZ - Repubblica Ceca 13
EG - Egitto 13
MA - Marocco 13
CL - Cile 12
KE - Kenya 12
MY - Malesia 12
CO - Colombia 11
LT - Lituania 11
SA - Arabia Saudita 11
AU - Australia 10
RO - Romania 10
IL - Israele 9
PY - Paraguay 9
CH - Svizzera 8
UY - Uruguay 7
DK - Danimarca 6
KG - Kirghizistan 6
BO - Bolivia 5
ET - Etiopia 5
JO - Giordania 5
KH - Cambogia 5
NP - Nepal 5
TH - Thailandia 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
DZ - Algeria 4
GY - Guiana 4
HU - Ungheria 4
KZ - Kazakistan 4
RS - Serbia 4
BY - Bielorussia 3
GR - Grecia 3
HN - Honduras 3
JM - Giamaica 3
MT - Malta 3
NI - Nicaragua 3
OM - Oman 3
PE - Perù 3
PT - Portogallo 3
SI - Slovenia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BG - Bulgaria 2
DM - Dominica 2
IR - Iran 2
KI - Kiribati 2
KW - Kuwait 2
LB - Libano 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
MK - Macedonia 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
AO - Angola 1
AW - Aruba 1
CG - Congo 1
CR - Costa Rica 1
CU - Cuba 1
DO - Repubblica Dominicana 1
Totale 67.545
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Città #
Woodbridge 16.490
Wilmington 13.851
Houston 12.769
Fairfield 1.473
Ann Arbor 1.376
Singapore 1.253
Kraków 1.251
Ashburn 1.033
Chandler 843
Jacksonville 714
Seattle 615
Cambridge 519
Hong Kong 500
San Jose 496
Dublin 441
Beijing 423
Medford 366
Dearborn 311
The Dalles 236
Santa Clara 214
New York 212
Council Bluffs 204
Lawrence 172
Los Angeles 154
Mülheim 127
Ho Chi Minh City 107
Helsinki 104
Menlo Park 104
Hanoi 101
San Diego 95
Buffalo 92
Tokyo 86
Moscow 76
Dallas 75
Rome 69
Boardman 66
Zhengzhou 66
São Paulo 61
Munich 57
Falls Church 54
Brussels 53
Lauterbourg 48
Milan 46
Mountain View 41
Toronto 41
London 40
University Park 40
Phoenix 38
San Mateo 37
Guangzhou 35
Rio de Janeiro 35
Orem 33
Detroit 32
Norwalk 31
Jakarta 29
Warsaw 29
Chicago 28
Daejeon 27
Montreal 27
Frankfurt am Main 26
Redondo Beach 26
Verona 26
Columbus 23
Redwood City 23
Shanghai 23
Brooklyn 21
Hefei 21
Nürnberg 20
Dong Ket 19
Haiphong 18
Kaiserslautern 18
Saint Petersburg 18
Stockholm 18
Atlanta 17
Baghdad 17
Belo Horizonte 17
Da Nang 17
Johannesburg 16
Amsterdam 15
Denver 15
Nuremberg 15
Palo Alto 15
San Francisco 15
Chennai 14
Jinan 14
Kunming 14
Paris 13
Fortaleza 12
Indianapolis 12
Manchester 12
Nanjing 12
Porto Alegre 12
Boston 11
Brasília 11
Indiana 11
Washington 11
Ankara 10
Guayaquil 10
Auburn Hills 9
Brno 9
Totale 58.602
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Nome #
A histidine-rich metal binding domain at the N terminus of Cu,Zn-superoxide dismutases from pathogenic bacteria 646
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 537
Pro-apoptotic activity of novel isatin-Schiff base copper(II) complexes depends on oxidative stress induction and organelle-selective damage 535
Low-Shear Modeled Microgravity Enhances Salmonella Enterica Resistance to Hydrogen Peroxide Through a Mechanism Involving KatG and KatN 522
Effects of water garlic extracts on cell cycle and viability of HepG2 hepatoma cells 519
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 519
Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS 515
Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis 508
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 506
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2 504
Increased expression of periplasmic Cu,Zn superoxide dismutase enhances survival of Escherichia coli invasive strains within nonphagocytic cells 502
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: a rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 501
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 499
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1 498
Imbalance in corneal redox state during herpes simplex virus 1-induced keratitis in rabbits. Effectiveness of exogenous glutathione supply 496
Toward the engineering of a super efficient enzyme 491
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of AMP-activated protein kinase/p38MAPK/p53 signalling axis Evidence for a combined use with 3-bromopyruvate in neuroblastoma treatment 490
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 489
Activation and induction by copper of Cu/Zn superoxide dismutase in Saccharomyces cerevisiae. Presence of an inactive proenzyme in anaerobic yeast 489
Isatin-Schiff base copper(II) complexes and their influence on cellular viability 487
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis 485
Regulation of CU, ZNSOD by metals in S-Cereivisiae and Zea-Mays 484
Distinctive functional features in prokaryotic and eukaryotic Cu,Zn superoxide dismutases 484
Intracellular GSH content and HIV replication in human macrophages 482
Attenuated Salmonella enterica serovar Typhimurium lacking the ZnuABC transporter confers immune-based protection against challenge infections in mice 482
Unique features of the sodC-encoded superoxide dismutase from Mycobacterium tuberculosis, a fully functional copper-containing enzyme lacking zinc in the active site 480
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals 479
Developmental expression of Cu,Zn superoxide dismutase in Xenopus. Constant level of the enzyme in oogenesis and embryogenesis 479
Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence 477
Rescue of cells from apoptosis by inhibition of active GSH extrusion 477
A study of the dual role of copper in superoxide dismutase as antioxidant and pro-oxidant in cellular models of amyotrophic lateral sclerosis 473
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 470
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 470
The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosis. 469
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 468
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells 467
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 467
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis 467
Non-oxidative loss of glutathione in apoptosis via GSH extrusion 466
Transduction of reducing power across the plasma membrane by reduced glutathione. A 1H-NMR spin-echo study of intact human erythrocytes 465
Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: electrophysiologic changes and ascorbyl radical formation 465
Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase 463
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 461
Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells 460
Xenopus laevis Cu,Zn superoxide dismutase B cDNA sequence 460
Redox bases underlying the anti-tumor activity of garlic-contained organo-sulfur compounds: Implication in chemoprevention and chemotherapy 459
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 458
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration 458
Purification and characterization of Ag,Zn-superoxide dismutase from Saccharomyces cerevisiae exposed to silver 458
Role of zinc-coordination and of the glutathione redox couple in the redox susceptibility of human transcription factor Sp1 458
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 456
Benefits from dietary polyphenols for brain aging and Alzheimer's disease 452
Copper-dependent oxidative stress and neurodegeneration 452
Correlation between superoxide dismutase, glutathione peroxidase and catalase in isolated rat hepatocytes during fetal development. 452
Transient cytoskeletal alterations after SOD1 depletion in neuroblastoma cells 451
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. 451
Superoxide dismutase 1 modulates expression of transferrin receptor 451
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials 451
Glutathione-related systems and modulation of extracellular signal-regulated kinases are involved in the resistance of AGS adenocarcinoma gastric cells to diallyl disulfide-induced apoptosis 450
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 449
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 449
Role of the electrostatic loop of Cu,Zn superoxide dismutase in the copper uptake process 448
Voltage-activated sodium currents in a cell line expressing a Cu,Zn superoxide dismutase typical of familial ALS 447
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 446
Thermal stability and redox properties of M. tuberculosis CuSOD 446
Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cells 446
Temperature-dependent protein folding in vivo--lower growth temperature increases yield of two genetic variants of Xenopus laevis Cu,Zn superoxide dismutase in Escherichia coli 445
In vivo formation of Cu,Zn superoxide dismutase disulfide bond in Escherichia coli 443
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 442
trans-Resveratrol induces apoptosis in human breast cancer cells MCF-7 by the activation of MAP kinases pathways 442
Disulfide relays and phosphorylative cascades: Partners in redox-mediated signaling pathways 440
Evidence for co-regulation of Cu,Zn superoxide dismutase and metallothionein gene expression in yeast through transcriptional control by copper via the ACE 1 factor 439
Crystallographic characterization and three-dimensional model of yeast Cu,Zn superoxide dismutase 438
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. 436
Copper-dependent toxicity in SH-SY5Y neuroblasoma cells involves mitochondrial damage. 436
Molecular modelling and electrostatic potential calculations on chemically modified Cu,Zn superoxide dismutases from Bos taurus and the shark Prionace glauca 436
Differential role of superoxide and glutathione in S-nitrosoglutathione-mediated apoptosis: A rationale for mild forms of familial amyotrophic lateral sclerosis associated with less active Cu,Zn superoxide dismutase mutants 435
Interplay of Cu,Zn superoxide dismutase and nitric oxide synthase in Neurodegenerative processes 434
Activity of protein phosphatase calcineurin is decreased in sporadic and familial amyotrophic lateral sclerosispatients 433
Antiapoptotic response to induced GSH depletion: Involvement of heat shock proteins and NF-kappa B activation 432
Periplasmic competition for zinc uptake between the metallochaperone ZnuA and Cu,Zn superoxide dismutase 432
Under the ROS…thiol network is the principal suspect for autophagy commitment. 432
Crystal structure solution and refinement of the semisynthetic cobalt -substituted bovine erythrocyte superoxide dismutase at 2.0Å resolution 432
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS 429
Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. 428
Cell signalling and the glutathione redox system 427
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression 427
Primary structure from amino acid and cDNA sequences of two Cu,Zn superoxide dismutase variants from Xenopus laevis 426
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis 425
Differential binding of anions to the active site of Cu,Zn superoxide dismutase. A study of the Co,Zn enzyme derivative 424
Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells 423
Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells 422
A free cysteine residue at the dimer interface decreases conformational stability of Xenopus laevis copper,zinc superoxide dismutase 421
Purification of iron superoxide dismutase from the cyanobacterium Anabaena cylindrica Lemm. and localization of the enzyme in heterocystsis by immunonogold labeling 419
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase 416
Overexpression of a hydrogen peroxide-resistant periplasmic Cu,Zn superoxide dismutase protects Escherichia coli from macrophage killing 415
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection 415
Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis 413
p38(MAPK)/p53 signalling axis mediates neuronal apoptosis in response to tetrahydrobiopterin-induced oxidative stress and glucose uptake inhibition: implication for neurodegeneration. 413
p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance 411
Totale 46.122
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Categoria #
all - tutte 141.381
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 141.381
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021470 0 0 0 0 0 0 0 0 0 0 328 142
2021/20221.947 65 168 117 118 79 187 90 74 288 128 89 544
2022/20232.278 225 134 38 347 228 518 165 161 214 12 192 44
2023/2024710 108 18 50 25 92 217 13 51 12 14 11 99
2024/20253.567 148 803 354 209 133 284 291 225 311 305 257 247
2025/20265.594 434 307 671 521 506 230 661 823 625 782 34 0
Totale 67.887