IRIS
FEDERICI, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 68.401
AS - Asia 9.770
EU - Europa 9.189
SA - Sud America 1.370
Continente sconosciuto - Info sul continente non disponibili 1.138
AF - Africa 192
OC - Oceania 33
Totale 90.093
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Nazione #
US - Stati Uniti d'America 67.997
SG - Singapore 4.339
CN - Cina 1.932
IT - Italia 1.724
DE - Germania 1.169
RU - Federazione Russa 1.153
BR - Brasile 1.097
UA - Ucraina 904
HK - Hong Kong 893
VN - Vietnam 817
FR - Francia 722
SE - Svezia 679
IE - Irlanda 663
PL - Polonia 640
BD - Bangladesh 501
GB - Regno Unito 475
FI - Finlandia 430
KR - Corea 281
JP - Giappone 277
CA - Canada 213
IN - India 194
NL - Olanda 145
ES - Italia 117
MX - Messico 103
ID - Indonesia 97
AR - Argentina 85
AT - Austria 77
ZA - Sudafrica 71
IQ - Iraq 61
BE - Belgio 59
TR - Turchia 59
EC - Ecuador 46
CZ - Repubblica Ceca 40
KG - Kirghizistan 39
CO - Colombia 35
CL - Cile 31
MA - Marocco 30
SA - Arabia Saudita 30
RO - Romania 28
VE - Venezuela 28
AU - Australia 27
LT - Lituania 27
PK - Pakistan 25
CH - Svizzera 22
KE - Kenya 22
UZ - Uzbekistan 22
PH - Filippine 21
GR - Grecia 20
JM - Giamaica 20
MY - Malesia 20
PY - Paraguay 20
EG - Egitto 19
IR - Iran 19
AE - Emirati Arabi Uniti 15
AZ - Azerbaigian 14
IL - Israele 14
KZ - Kazakistan 12
TH - Thailandia 12
TN - Tunisia 12
UY - Uruguay 12
DK - Danimarca 11
DZ - Algeria 11
LB - Libano 11
PE - Perù 11
PT - Portogallo 11
CR - Costa Rica 10
EU - Europa 10
HN - Honduras 10
JO - Giordania 9
NP - Nepal 9
AL - Albania 8
BS - Bahamas 8
HR - Croazia 8
GT - Guatemala 7
HU - Ungheria 7
NO - Norvegia 7
OM - Oman 7
AD - Andorra 6
AO - Angola 6
NG - Nigeria 6
AF - Afghanistan, Repubblica islamica di 5
DO - Repubblica Dominicana 5
KW - Kuwait 5
NI - Nicaragua 5
RS - Serbia 5
TT - Trinidad e Tobago 5
TW - Taiwan 5
EE - Estonia 4
GE - Georgia 4
LV - Lettonia 4
MK - Macedonia 4
MT - Malta 4
NZ - Nuova Zelanda 4
SI - Slovenia 4
SV - El Salvador 4
BG - Bulgaria 3
BO - Bolivia 3
BY - Bielorussia 3
CW - ???statistics.table.value.countryCode.CW??? 3
CY - Cipro 3
Totale 88.911
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Città #
Woodbridge 18.884
Wilmington 16.921
Houston 11.864
Singapore 2.518
Fairfield 2.403
Ashburn 1.921
Ann Arbor 1.578
Chandler 1.297
San Jose 1.045
Seattle 945
Hong Kong 866
Cambridge 795
Jacksonville 766
Beijing 704
New York 672
Dublin 645
Council Bluffs 628
Kraków 566
Rome 510
Medford 480
Santa Clara 422
Los Angeles 400
The Dalles 351
Dearborn 343
Ho Chi Minh City 259
Stockholm 259
Tokyo 247
Buffalo 239
Dallas 237
Lawrence 229
Helsinki 212
Hanoi 182
Moscow 165
Zhengzhou 164
San Diego 157
Lauterbourg 146
Milan 138
São Paulo 137
Menlo Park 124
Munich 123
Orem 123
Mülheim 102
Frankfurt am Main 101
Boardman 96
London 88
Chicago 87
North Bergen 67
Toronto 66
Brooklyn 64
Phoenix 64
Atlanta 63
Nuremberg 63
Jakarta 62
Chennai 59
Brussels 58
Warsaw 58
Shanghai 55
Johannesburg 49
Columbus 47
Montreal 47
Denver 45
Redondo Beach 44
Guangzhou 42
Norwalk 42
Verona 42
Nanjing 41
Hangzhou 40
San Francisco 40
Manchester 39
Palo Alto 39
Boston 38
Falls Church 37
Mexico City 37
Amsterdam 36
Detroit 35
Kunming 35
Creede 33
Haiphong 33
Da Nang 32
Rio de Janeiro 32
San Mateo 32
Seoul 32
Vienna 31
Brno 30
Lappeenranta 30
Mumbai 29
Redwood City 27
Salt Lake City 26
University Park 26
Mountain View 25
Naples 25
Ankara 24
Bologna 24
Hefei 24
Saint Petersburg 24
Dhaka 23
Bari 22
Belo Horizonte 22
Madrid 22
Poplar 21
Totale 73.242
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Nome #
Metabolomics signature improves the prediction of cardiovascular events in elderly subjects 752
Peroxiredoxin 6, a novel player in the pathogenesis of diabetes 602
A Role for Timp3 in Microbiota-Driven Hepatic Steatosis and Metabolic Dysfunction 587
Role of serum and glucocorticoid-inducible kinase (SGK)-1 in senescence: a novel molecular target against age-related diseases 558
A score including ADAM17 substrates correlates to recurring cardiovascular event in subjects with atherosclerosis 555
Frequent follow-up visits reduce weight regain in long-term management after bariatric surgery 551
C-peptide: A predictor of cardiovascular mortality in subjects with established atherosclerotic disease 551
TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice. 542
Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis 530
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1 522
Liver protein profiles in insulin receptor-knockout mice reveal novel molecules involved in the diabetes pathophysiology 520
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis 506
Effects of whole body vibration plus diet on insulin-resistance in middle-aged obese subjects 497
A1c value for diabetes diagnosis in subjects with established cardiovascular disease 496
Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy 494
Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients 488
MiR-216a: a link between endothelial dysfunction and autophagy 487
Omental adipose tissue fibrosis and insulin resistance in severe obesity 486
Iron status in obesity: An independent association with metabolic parameters and effect of weight loss 484
SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α 484
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes 483
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser(307) and Ser(612) and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells 481
ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice 481
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects 479
Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: Role of lipoxidation via receptor-mediated mechanisms 472
A genetic marker of hyperuricemia predicts cardiovascular events in a meta-analysis of three cohort studies in high risk patients 472
Decreased IRS2 and TIMP3 Expression in Monocytes From Offspring of Type 2 Diabetic Patients Is Correlated With Insulin Resistance and Increased Intima-Media Thickness 471
Transgenic mice with dominant negative PKC-theta in skeletal muscle: A new model of insulin resistance and obesity 469
Atherosclerosis severity but not undiagnosed diabetes predicts new cardiovascular events of subjects in secondary cardiovascular prevention. 469
Serum- and Glucocorticoid-Inducible Kinase 1 Delay the Onset of Endothelial Senescence by Directly Interacting with Human Telomerase Reverse Transcriptase 469
Toll-like receptor 4 mediates endothelial cell activation through NF-κB but is not associated with endothelial dysfunction in patients with rheumatoid arthritis 466
IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity 466
Nonalcoholic fatty liver disease and age are strong indicators for atherosclerosis in morbid obesity 465
Changes in blood microbiota profiles associated with liver fibrosis in obese patients: A pilot analysis 465
Sildenafil reduces insulin-resistance in human endothelial cells 464
Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia 463
Electrophysiological and amperometric evidence that modafinil blocks the dopamine uptake transporter to induce behavioral activation 462
Insulin receptor substrate (IRS) transduction system: Distinct and overlapping signaling potential 462
Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity 461
Serum 25-hydroxyvitamin D levels are inversely associated with systemic inflammation in severe obese subjects 461
Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia 461
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay 460
Erratum: A Role for Timp3 in Microbiota-Driven Hepatic Steatosis and Metabolic Dysfunction (Cell Reports (2016) 16(3) (731–743) (S2211124716307677) (10.1016/j.celrep.2016.06.027)) 460
IL12B polymorphism and type 1 diabetes in the Italian population: A case-control study 459
Elbow deformities in a patient with mandibuloacral dysplasia type A 459
Can renin inhibition by Aliskiren prove itself in atherosclerosis prevention? 456
Parathyroid hormone and insulin resistance in distinct phenotypes of severe obesity: a cross-sectional analysis in middle-aged men and premenopausal women 453
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient 451
Expression of tissue inhibitor of metalloprotease 3 is reduced in ischemic but not neuropathic ulcers from patients with type 2 diabetes mellitus 451
Insulin resistance affects gene expression in endothelium 450
Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling 448
Effects of Dipeptidyl Peptidase 4 Inhibitors and Sodium-Glucose Linked coTransporter-2 Inhibitors on cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis 448
Human placental lactogen (hPL-A) activates signaling pathways linked to cell survival and improves insulin secretion in human pancreatic islets 447
Metabolic syndrome and risk of pulmonary involvement 447
Loss of TIMP3 exacerbates atherosclerosis in ApoE null mice 446
Carotid plaque unstability is not related to quantity but to elemental composition of calcification 446
"The Linosa Study": Epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate 445
Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and non-ischemic injury in the mouse 444
Polymorphisms of the insulin receptor subtrate-2 in patients with type 2 diabetes 443
Adiponectin isoforms are not associated with the severity of coronary atherosclerosis but with undiagnosed diabetes in patients affected by stable CAD 442
Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus 441
Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction. 439
Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: role of lipoxidation via receptor-mediated mechanisms 438
ITCH deficiency protects from diet-induced obesity 438
Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome 437
MicroRNAs in vascular aging and atherosclerosis 437
Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation 436
Impaired endothelial function in never-treated hypertensive subjects carrying the Arg972 polymorphism in the insulin receptor substrate-1 gene 436
TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1 436
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes 435
Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance 435
The strange case of G972R IRS-1 variant and diabetes. Do type 1 and type 2 diabetes share common genes? 434
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders 433
Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion 433
The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism 433
Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes 430
The strange case of G972R IRS-1 variant and diabetes. Do type 1 and type 2 diabetes share common genes? 430
Tissue Inhibitor of Metalloproteinase-3 Regulates Inflammation in Human and Mouse Intestine. 430
The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets. 428
Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice 428
Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs. 426
Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome 426
Delayed intracellular dissociation of the insulin-receptor complex impairs receptor recycling and insulin processing in cultured Epstein-Barr virus-transformed lymphocytes from insulin-resistant subjects 425
Serum resistin, cardiovascular disease and all-cause mortality in patients with type 2 diabetes. 425
Adiponectin isoforms in elderly patients with or without coronary artery disease 424
Age-Related Different Relationships between Ectopic Adipose Tissues and Measures of Central Obesity in Sedentary Subjects 422
Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice 421
Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes 421
The Gly -> Arg(972) amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells 420
The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients 420
Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues 415
High mobility group box 1 is a novel substrate of dipeptidyl peptidase-IV 415
Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice 415
The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms 413
Low Molecular Weight Adiponectin Increases the Mortality Risk in Very Old Patients 413
MicroRNA 21 is up-regulated in adipose tissue of obese diabetic subjects 412
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells 411
Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly 410
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders 409
The Linosa Study: epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate 409
Totale 46.128
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Categoria #
all - tutte 231.069
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 231.069
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.485 0 253 134 102 72 277 238 94 195 288 154 678
2022/20233.309 338 279 143 422 316 691 302 202 260 15 248 93
2023/20241.455 128 29 89 31 136 514 66 114 26 59 44 219
2024/20257.003 447 1.522 724 378 243 483 556 321 608 583 693 445
2025/202613.652 1.035 551 1.413 1.103 1.230 519 1.835 1.424 1.612 1.451 787 692
2026/20271.872 974 898 0 0 0 0 0 0 0 0 0 0
Totale 90.093