IRIS
FEDERICI, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 67.057
AS - Asia 9.481
EU - Europa 8.841
SA - Sud America 1.353
AF - Africa 191
OC - Oceania 33
Continente sconosciuto - Info sul continente non disponibili 14
Totale 86.970
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Nazione #
US - Stati Uniti d'America 66.739
SG - Singapore 4.316
CN - Cina 1.897
IT - Italia 1.484
DE - Germania 1.164
RU - Federazione Russa 1.142
BR - Brasile 1.090
UA - Ucraina 902
HK - Hong Kong 883
VN - Vietnam 808
FR - Francia 722
IE - Irlanda 663
PL - Polonia 640
SE - Svezia 621
GB - Regno Unito 471
FI - Finlandia 430
BD - Bangladesh 304
KR - Corea 280
JP - Giappone 273
IN - India 193
CA - Canada 174
NL - Olanda 128
ES - Italia 111
ID - Indonesia 97
MX - Messico 97
AR - Argentina 84
AT - Austria 77
ZA - Sudafrica 70
IQ - Iraq 61
BE - Belgio 59
TR - Turchia 58
EC - Ecuador 46
CZ - Repubblica Ceca 40
KG - Kirghizistan 39
CO - Colombia 31
CL - Cile 30
MA - Marocco 30
AU - Australia 27
LT - Lituania 27
SA - Arabia Saudita 27
VE - Venezuela 27
RO - Romania 26
PK - Pakistan 25
CH - Svizzera 22
KE - Kenya 22
UZ - Uzbekistan 22
PH - Filippine 21
GR - Grecia 20
EG - Egitto 19
IR - Iran 19
MY - Malesia 18
PY - Paraguay 18
AE - Emirati Arabi Uniti 14
AZ - Azerbaigian 14
IL - Israele 12
KZ - Kazakistan 12
TH - Thailandia 12
TN - Tunisia 12
DK - Danimarca 11
DZ - Algeria 11
LB - Libano 11
PE - Perù 11
UY - Uruguay 11
EU - Europa 10
PT - Portogallo 10
JO - Giordania 9
NP - Nepal 9
AL - Albania 8
HN - Honduras 8
HR - Croazia 8
JM - Giamaica 8
HU - Ungheria 7
NO - Norvegia 7
OM - Oman 7
AD - Andorra 6
AO - Angola 6
GT - Guatemala 6
NG - Nigeria 6
AF - Afghanistan, Repubblica islamica di 5
BS - Bahamas 5
CR - Costa Rica 5
KW - Kuwait 5
RS - Serbia 5
TW - Taiwan 5
EE - Estonia 4
GE - Georgia 4
LV - Lettonia 4
MT - Malta 4
NZ - Nuova Zelanda 4
SI - Slovenia 4
BO - Bolivia 3
BY - Bielorussia 3
CY - Cipro 3
DO - Repubblica Dominicana 3
MK - Macedonia 3
PS - Palestinian Territory 3
SN - Senegal 3
XK - ???statistics.table.value.countryCode.XK??? 3
AM - Armenia 2
BG - Bulgaria 2
Totale 86.922
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Città #
Woodbridge 18.884
Wilmington 16.920
Houston 11.855
Singapore 2.504
Fairfield 2.403
Ashburn 1.794
Ann Arbor 1.578
Chandler 1.297
San Jose 975
Seattle 936
Hong Kong 859
Cambridge 795
Jacksonville 764
Beijing 693
New York 649
Dublin 645
Kraków 566
Rome 480
Medford 478
Council Bluffs 436
Santa Clara 398
The Dalles 349
Dearborn 343
Los Angeles 310
Stockholm 259
Ho Chi Minh City 255
Tokyo 245
Lawrence 229
Buffalo 220
Dallas 219
Helsinki 212
Hanoi 179
Moscow 165
Zhengzhou 164
San Diego 152
Lauterbourg 146
São Paulo 136
Menlo Park 124
Munich 123
Orem 121
Mülheim 102
Frankfurt am Main 101
Milan 99
London 84
Chicago 79
Boardman 76
Jakarta 62
North Bergen 61
Nuremberg 60
Atlanta 59
Chennai 59
Toronto 59
Brussels 58
Warsaw 58
Brooklyn 57
Shanghai 55
Johannesburg 49
Phoenix 49
Redondo Beach 44
Guangzhou 42
Norwalk 42
Denver 41
Nanjing 41
Verona 41
Hangzhou 40
Montreal 39
Palo Alto 39
Manchester 36
Amsterdam 35
Boston 35
Falls Church 35
Kunming 35
San Francisco 35
Columbus 34
Creede 33
Haiphong 33
Da Nang 32
Detroit 32
Mexico City 32
Rio de Janeiro 32
San Mateo 32
Seoul 31
Vienna 31
Brno 30
Lappeenranta 30
Mumbai 29
Redwood City 27
University Park 26
Mountain View 25
Hefei 24
Saint Petersburg 24
Salt Lake City 24
Ankara 23
Belo Horizonte 22
Dhaka 22
Bologna 21
Madrid 21
Naples 21
Poplar 21
Paris 20
Totale 72.399
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Nome #
Metabolomics signature improves the prediction of cardiovascular events in elderly subjects 747
Peroxiredoxin 6, a novel player in the pathogenesis of diabetes 599
A Role for Timp3 in Microbiota-Driven Hepatic Steatosis and Metabolic Dysfunction 580
Role of serum and glucocorticoid-inducible kinase (SGK)-1 in senescence: a novel molecular target against age-related diseases 552
A score including ADAM17 substrates correlates to recurring cardiovascular event in subjects with atherosclerosis 548
C-peptide: A predictor of cardiovascular mortality in subjects with established atherosclerotic disease 548
Frequent follow-up visits reduce weight regain in long-term management after bariatric surgery 542
TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice. 541
Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis 526
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1 517
Liver protein profiles in insulin receptor-knockout mice reveal novel molecules involved in the diabetes pathophysiology 511
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis 498
Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy 492
Effects of whole body vibration plus diet on insulin-resistance in middle-aged obese subjects 492
A1c value for diabetes diagnosis in subjects with established cardiovascular disease 491
Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients 486
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser(307) and Ser(612) and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells 480
Omental adipose tissue fibrosis and insulin resistance in severe obesity 480
SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α 479
Iron status in obesity: An independent association with metabolic parameters and effect of weight loss 478
MiR-216a: a link between endothelial dysfunction and autophagy 476
ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice 475
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects 474
Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: Role of lipoxidation via receptor-mediated mechanisms 468
Transgenic mice with dominant negative PKC-theta in skeletal muscle: A new model of insulin resistance and obesity 468
Decreased IRS2 and TIMP3 Expression in Monocytes From Offspring of Type 2 Diabetic Patients Is Correlated With Insulin Resistance and Increased Intima-Media Thickness 466
Serum- and Glucocorticoid-Inducible Kinase 1 Delay the Onset of Endothelial Senescence by Directly Interacting with Human Telomerase Reverse Transcriptase 466
Nonalcoholic fatty liver disease and age are strong indicators for atherosclerosis in morbid obesity 464
Atherosclerosis severity but not undiagnosed diabetes predicts new cardiovascular events of subjects in secondary cardiovascular prevention. 463
Changes in blood microbiota profiles associated with liver fibrosis in obese patients: A pilot analysis 462
Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia 461
Sildenafil reduces insulin-resistance in human endothelial cells 461
Toll-like receptor 4 mediates endothelial cell activation through NF-κB but is not associated with endothelial dysfunction in patients with rheumatoid arthritis 461
IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity 461
Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity 459
Serum 25-hydroxyvitamin D levels are inversely associated with systemic inflammation in severe obese subjects 459
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay 457
Electrophysiological and amperometric evidence that modafinil blocks the dopamine uptake transporter to induce behavioral activation 457
Elbow deformities in a patient with mandibuloacral dysplasia type A 456
Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia 456
Can renin inhibition by Aliskiren prove itself in atherosclerosis prevention? 456
Erratum: A Role for Timp3 in Microbiota-Driven Hepatic Steatosis and Metabolic Dysfunction (Cell Reports (2016) 16(3) (731–743) (S2211124716307677) (10.1016/j.celrep.2016.06.027)) 455
Insulin receptor substrate (IRS) transduction system: Distinct and overlapping signaling potential 455
IL12B polymorphism and type 1 diabetes in the Italian population: A case-control study 453
A genetic marker of hyperuricemia predicts cardiovascular events in a meta-analysis of three cohort studies in high risk patients 453
Insulin resistance affects gene expression in endothelium 449
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient 446
Expression of tissue inhibitor of metalloprotease 3 is reduced in ischemic but not neuropathic ulcers from patients with type 2 diabetes mellitus 446
Parathyroid hormone and insulin resistance in distinct phenotypes of severe obesity: a cross-sectional analysis in middle-aged men and premenopausal women 446
Metabolic syndrome and risk of pulmonary involvement 445
Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling 445
Effects of Dipeptidyl Peptidase 4 Inhibitors and Sodium-Glucose Linked coTransporter-2 Inhibitors on cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis 443
"The Linosa Study": Epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate 441
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes 440
Polymorphisms of the insulin receptor subtrate-2 in patients with type 2 diabetes 440
Adiponectin isoforms are not associated with the severity of coronary atherosclerosis but with undiagnosed diabetes in patients affected by stable CAD 440
Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and non-ischemic injury in the mouse 440
Carotid plaque unstability is not related to quantity but to elemental composition of calcification 440
Loss of TIMP3 exacerbates atherosclerosis in ApoE null mice 439
Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction. 438
Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus 438
Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: role of lipoxidation via receptor-mediated mechanisms 435
ITCH deficiency protects from diet-induced obesity 435
Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome 434
Occult impaired glucose regulation in patients with atherosclerosis is associated to the number of affected vascular districts and inflammation 433
Impaired endothelial function in never-treated hypertensive subjects carrying the Arg972 polymorphism in the insulin receptor substrate-1 gene 433
The strange case of G972R IRS-1 variant and diabetes. Do type 1 and type 2 diabetes share common genes? 432
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes 432
Human placental lactogen (hPL-A) activates signaling pathways linked to cell survival and improves insulin secretion in human pancreatic islets 432
MicroRNAs in vascular aging and atherosclerosis 432
Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes 430
The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism 430
Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion 429
Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance 429
TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1 428
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders 427
Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice 427
The strange case of G972R IRS-1 variant and diabetes. Do type 1 and type 2 diabetes share common genes? 426
Tissue Inhibitor of Metalloproteinase-3 Regulates Inflammation in Human and Mouse Intestine. 426
The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets. 425
Adiponectin isoforms in elderly patients with or without coronary artery disease 423
Delayed intracellular dissociation of the insulin-receptor complex impairs receptor recycling and insulin processing in cultured Epstein-Barr virus-transformed lymphocytes from insulin-resistant subjects 422
Endothelial function and arterial stiffness in normotensive normoglycemic first-degree relatives of diabetic patients are independent of the metabolic syndrome 421
The Gly -> Arg(972) amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells 420
Serum resistin, cardiovascular disease and all-cause mortality in patients with type 2 diabetes. 420
Age-Related Different Relationships between Ectopic Adipose Tissues and Measures of Central Obesity in Sedentary Subjects 419
Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes 418
Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs. 418
Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice 417
The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients 414
Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues 413
The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms 411
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells 410
High mobility group box 1 is a novel substrate of dipeptidyl peptidase-IV 410
Proteomic and metabolomic characterization of streptozotocin-induced diabetic nephropathy in TIMP3-deficient mice 410
MicroRNA 21 is up-regulated in adipose tissue of obese diabetic subjects 408
Low Molecular Weight Adiponectin Increases the Mortality Risk in Very Old Patients 408
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders 407
Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly 404
Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response 404
Totale 45.657
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Categoria #
all - tutte 220.190
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 220.190
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021150 0 0 0 0 0 0 0 0 0 0 0 150
2021/20222.585 100 253 134 102 72 277 238 94 195 288 154 678
2022/20233.309 338 279 143 422 316 691 302 202 260 15 248 93
2023/20241.455 128 29 89 31 136 514 66 114 26 59 44 219
2024/20257.003 447 1.522 724 378 243 483 556 321 608 583 693 445
2025/202613.522 1.035 551 1.413 1.103 1.230 519 1.835 1.424 1.612 1.451 787 562
Totale 88.091