The O subfamily of forkhead (FoxO) 1 is a pivotal element in the regulation of endothelial activation. Compartmentalization and activity of FoxO1 is regulated by post translational modifications, but the implication in endothelial dysfunction and atherosclerosis remain controversial. Our aim was to identify FoxO1 related metabolic signatures in endothelial cells.
Menghini, R., Casagrande, V., Cardellini, M., Ballanti, M., Davato, F., Cardolini, I., et al. (2015). FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis. ATHEROSCLEROSIS, 242(1), 230-235 [10.1016/j.atherosclerosis.2015.07.026].
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis
MENGHINI, ROSSELLA;CARDELLINI, MARINA;BALLANTI, MARTA;FABRIZI, MARTA;ANEMONA, LUCIA;IPPOLITI, ARNALDO;MAURIELLO, ALESSANDRO;FEDERICI, MASSIMO
2015-01-01
Abstract
The O subfamily of forkhead (FoxO) 1 is a pivotal element in the regulation of endothelial activation. Compartmentalization and activity of FoxO1 is regulated by post translational modifications, but the implication in endothelial dysfunction and atherosclerosis remain controversial. Our aim was to identify FoxO1 related metabolic signatures in endothelial cells.| File | Dimensione | Formato | |
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