IRIS
DESIDERI, ALESSANDRO
 Distribuzione geografica
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Continente #
NA - Nord America 77.280
EU - Europa 11.178
AS - Asia 7.168
SA - Sud America 1.151
AF - Africa 118
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 16
Totale 96.932
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Nazione #
US - Stati Uniti d'America 77.044
SG - Singapore 3.517
PL - Polonia 3.328
FR - Francia 1.692
CN - Cina 1.384
DE - Germania 1.085
UA - Ucraina 1.026
BR - Brasile 979
RU - Federazione Russa 926
SE - Svezia 680
IT - Italia 675
IE - Irlanda 672
HK - Hong Kong 647
VN - Vietnam 608
GB - Regno Unito 446
FI - Finlandia 323
KR - Corea 319
JP - Giappone 183
CA - Canada 121
IN - India 117
MX - Messico 71
BE - Belgio 64
AR - Argentina 59
ID - Indonesia 51
BD - Bangladesh 50
NL - Olanda 49
AT - Austria 48
IQ - Iraq 47
ES - Italia 46
ZA - Sudafrica 44
TR - Turchia 43
EC - Ecuador 27
CO - Colombia 22
PK - Pakistan 18
SA - Arabia Saudita 18
PH - Filippine 17
UZ - Uzbekistan 17
AU - Australia 16
CH - Svizzera 16
CL - Cile 16
CZ - Repubblica Ceca 16
IL - Israele 16
AE - Emirati Arabi Uniti 15
MA - Marocco 15
RO - Romania 15
TW - Taiwan 14
VE - Venezuela 14
EU - Europa 13
KG - Kirghizistan 13
LT - Lituania 13
PE - Perù 13
GR - Grecia 12
KE - Kenya 12
EG - Egitto 11
IR - Iran 11
JO - Giordania 11
MY - Malesia 11
JM - Giamaica 9
TN - Tunisia 8
AL - Albania 7
BO - Bolivia 7
NP - Nepal 7
PY - Paraguay 7
HN - Honduras 6
HR - Croazia 6
SN - Senegal 6
TH - Thailandia 6
UY - Uruguay 6
AZ - Azerbaigian 5
CR - Costa Rica 5
DZ - Algeria 5
KZ - Kazakistan 5
NO - Norvegia 5
PT - Portogallo 5
DK - Danimarca 4
DO - Repubblica Dominicana 4
RS - Serbia 4
CI - Costa d'Avorio 3
DM - Dominica 3
GE - Georgia 3
MD - Moldavia 3
NZ - Nuova Zelanda 3
OM - Oman 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
BG - Bulgaria 2
ET - Etiopia 2
GT - Guatemala 2
LB - Libano 2
LK - Sri Lanka 2
LV - Lettonia 2
ML - Mali 2
NI - Nicaragua 2
PA - Panama 2
PR - Porto Rico 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
Totale 96.907
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Città #
Woodbridge 22.799
Wilmington 19.426
Houston 17.685
Kraków 3.276
Fairfield 2.303
Ann Arbor 1.833
Singapore 1.710
Ashburn 1.388
Chandler 1.206
Seattle 924
Jacksonville 911
San Jose 823
Cambridge 792
Dublin 662
Hong Kong 639
Beijing 565
Medford 504
Dearborn 493
New York 483
The Dalles 285
Rome 272
Council Bluffs 266
Santa Clara 248
Lawrence 232
Los Angeles 226
Ho Chi Minh City 178
Tokyo 152
Moscow 141
Hanoi 139
Lauterbourg 131
Menlo Park 131
Buffalo 121
Boardman 115
San Diego 114
Mülheim 104
Helsinki 101
Zhengzhou 94
São Paulo 93
Dallas 83
Milan 77
Munich 65
Brussels 59
Mountain View 56
Norwalk 56
Chicago 53
London 52
Nuremberg 52
Warsaw 48
Montreal 45
Orem 43
Rio de Janeiro 43
Daejeon 42
Falls Church 42
Redwood City 41
Atlanta 39
Guangzhou 39
Redondo Beach 39
Toronto 38
Shanghai 37
Brooklyn 36
University Park 36
Phoenix 34
Verona 34
San Francisco 33
Belo Horizonte 29
Denver 29
Jakarta 28
North Bergen 28
San Mateo 28
Hefei 27
Mexico City 27
Nanjing 27
Da Nang 26
Johannesburg 26
Chennai 25
Kunming 25
Frankfurt am Main 23
Boston 22
Haiphong 22
Stockholm 22
Brasília 21
Hangzhou 21
Poplar 21
Vienna 21
Amsterdam 20
Washington 20
Nürnberg 19
Baghdad 18
Creede 17
Palo Alto 17
Seoul 17
Manchester 16
Mumbai 16
Salt Lake City 16
Saint Petersburg 15
Campinas 14
Charlotte 14
Columbus 14
Nanchang 14
Fortaleza 13
Totale 83.545
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Nome #
PVA engineered microcapsules for targeted delivery of camptothecin to HeLa cells 629
Molecular Dynamics Simulation of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha: evidence of a dynamical relationship between helices 3 and 5. 584
A natural anticancer agent thaspine targets human topoisomerase IB 558
DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family 548
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 535
Gene expression profile study in CFTR mutated bronchial cell lines 534
Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase 521
A Simple and Fast Semiautomatic Procedure for the Atomistic Modeling of Complex DNA Polyhedra 521
10-undecanhydroxamic acid, a hydroxamate derivative of the undecanoic acid, has strong antimicrobial activity through a mechanism that limits iron availability 520
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 519
Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B 518
In vitro analysis of pyrogenicity and cytotoxicity profiles of flex sensors to be used to sense human joint postures 515
A structural modeling approach for the understanding of initiation and elongation of ALS-linked superoxide dismutase fibrils 513
Structural-dynamical investigation of the ZnuA histidine-rich loop: involvement in zinc management and transport 510
Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy 508
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 506
Interaction between natural compounds and human topoisomerase I 505
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I 505
New hints on the pH-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach 504
Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation. 504
Functional and crystallographic characterization of Salmonella typhimurium Cu,Zn superoxide dismutase coded by the sodCI virulence gene 500
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 499
Simulative and experimental characterization of a pH-dependent clamp-like DNA triple-helix nanoswitch 499
A model for the incorporation of the metal from the copper chaperone CCS to Cu,Zn superoxide dismutase 497
Adsorption of the cysteine–tryptophan dipeptide at the Au(110)/liquid interface studied using reflection anisotropy spectroscopy 496
Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages 496
Dynamic changes in gene expression profiles of 22q11 and related orthologous genes during mouse development 495
Design of a novel LOX-1 receptor antagonist mimicking the natural substrate 493
Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: A spectroscopic and molecular modelling study 492
Toward the engineering of a super efficient enzyme 491
Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain 490
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 488
Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies 488
Role of human topoisomerase IB on ionizing radiation induced damage. 488
Anion size modulates the structure of the a state of cytochrome c 487
Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity. 487
X-ray absorption investigation of a unique protein domain able to bind both copper(I) and copper(II) at adjacent sites of the N-terminus of Haemophilus ducreyi Cu,Zn superoxide dismutase 486
Formation of a molten-globule-like state of cytochrome c induced by high concentrations of glycerol 485
Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1 485
Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin. 484
The Essential Dynamics of Cu,Zn superoxide dismutase: Suggestion of intersubunit communication 484
Thermophilicity of wild type and mutant cold shock proteins by molecular dynamics simulation. 482
Solvent dependency of the UV-Vis spectrum of indenoisoquinolines: role of keto-oxygens as polarity interaction probes. 481
Molecular dynamics simulations of the Trp repressor–DNA complex and the AV77 mutant 480
Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase 479
Structure and stability of the insulin dimer investigated by molecular dynamics simulation 477
A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 476
Effect of temperature and hydration on protein fluctuations: molecular dynamics simulation of Cu, Zn superoxide dismutase at six different temperatures. Comparison with neutron scattering data 476
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 474
Solvent Effects on the Valence UV-Vis Absorption Spectra of Topotecan Anticancer Drug in Aqueous Solution at Room Temperature: A Nanoseconds Time-scale TD-DFT/MD Computational Study 473
Virtual Screening for the Development of Dual-Inhibitors Targeting Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 473
Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene 473
Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage 472
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 470
An electrochemical multienzymatic biosensor for determination of cholesterol 470
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 469
Beta-bungarotoxin-mediated liposome fusion: spectroscopic characterization by fluorescence and ESR. 469
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 468
Assignment of UV-vis spectrum of (3,3')-diindolylmethane, a Leishmania donovani topoisomerase IB inhibitor and a candidate DNA minor groove binder. 468
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 467
Structure of nano-Scale Truncated Octahedral DNA Cages: Variation of Single-stranded Linker Regions and Influence on Assembly Yields. 467
Cells microenvironment engineering multiphoton absorption for muscle regeneration optimization 467
Influence of the single-strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano-cage family 466
The open state of human topoisomerase I as probed by molecular dynamics simulation 465
Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines 464
Single mutation induces a metal-dependent subunit association in dimeric Cu,Zn superoxide dismutase 463
Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface. 463
Molecular mechanism of statin-mediated LOX-1 inhibition 463
Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling 462
An amber compatible molecular mechanics force field for the anticancer drug topotecan 461
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 461
An electrostatic enzyme-substrate recognition: the case of Cu,Zn superoxide dismutase 461
Valproic acid induces neuroendocrine differentiation and UGT2B7 up-regulation in human prostate carcinoma cell line 458
The mitochondrial oxoglutarate carrier: Structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling 458
MD simulations of papillomavirus DNA-E2 protein complexes hints at a protein structural code for DNA deformation. 458
Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant. 458
Oxidovanadium(IV) complexes with chrysin and silibinin: Anticancer activity and mechanisms of action in a human colon adenocarcinoma model 458
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 457
Simulative Analysis of a Truncated Octahedral DNA Nanocage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability 457
Calculation of local electric fields in Shark Cu,Zn superoxide dismutase 457
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 456
Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol 456
The Potential of Nucleic Acid-Based Nanoparticles for Biomedical Application 456
A Small Sided Game session effects salivary metabolic levels in young soccer players 456
Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences. 455
Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and ruminant hemoglobins: a comparative study 454
Targeting Tumor Cells through Chitosan-Folate Modified Microcapsules Loaded with Camptothecin 454
Characterization of a novel CYP2C9 gene mutation and structural bioinformatic protein analysis in a warfarin hypersensitive patient 454
Role of the helix capping in the stability of the mouse prion (180-213) segment: investigation through molecular dynamics simulations 453
Reduced sensitivity of O2 transport to allosteric effectors and temperature in loggerhead sea turtle hemoglobin: functional and spectroscopic study 452
Geometrical constraints limiting the poly(ADP-ribose) conformation investigated by molecular dynamics simulation. 451
The heme-containing N-fragment (residues 1-56) of cytochrome c is a bis-histidine functional system 450
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 449
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 449
A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function 448
Molecular dynamics simulations of Cu,Zn superoxide dismutase: effect of temperature on dimer asymmetry 447
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 446
Superoxide Dismutase Kinetics 445
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations 444
Superefficient Enzymes 443
Totale 48.106
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Categoria #
all - tutte 201.437
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 201.437
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021982 0 0 0 0 0 0 0 0 0 328 481 173
2021/20222.616 128 230 272 175 65 208 125 79 272 207 157 698
2022/20233.179 315 219 64 438 310 753 286 201 300 6 206 81
2023/20241.221 137 40 65 47 118 456 25 47 17 16 17 236
2024/20255.527 194 1.003 507 263 294 403 396 323 513 510 616 505
2025/20267.933 735 371 1.032 762 708 348 1.029 1.180 875 893 0 0
Totale 97.602