IRIS
DESIDERI, ALESSANDRO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 78.351
EU - Europa 11.358
AS - Asia 7.443
SA - Sud America 1.166
Continente sconosciuto - Info sul continente non disponibili 686
AF - Africa 118
OC - Oceania 21
Totale 99.143
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 78.041
SG - Singapore 3.542
PL - Polonia 3.331
FR - Francia 1.692
CN - Cina 1.426
DE - Germania 1.085
UA - Ucraina 1.027
BR - Brasile 987
RU - Federazione Russa 928
IT - Italia 814
SE - Svezia 699
IE - Irlanda 672
HK - Hong Kong 653
VN - Vietnam 613
GB - Regno Unito 446
FI - Finlandia 323
KR - Corea 320
BD - Bangladesh 237
JP - Giappone 183
CA - Canada 151
IN - India 117
MX - Messico 74
BE - Belgio 64
AR - Argentina 59
NL - Olanda 56
ID - Indonesia 53
ES - Italia 51
AT - Austria 48
IQ - Iraq 47
TR - Turchia 44
ZA - Sudafrica 44
EC - Ecuador 28
CO - Colombia 25
JM - Giamaica 19
PK - Pakistan 18
SA - Arabia Saudita 18
CH - Svizzera 17
CL - Cile 17
CZ - Repubblica Ceca 17
PH - Filippine 17
UZ - Uzbekistan 17
AU - Australia 16
IL - Israele 16
AE - Emirati Arabi Uniti 15
MA - Marocco 15
MY - Malesia 15
PE - Perù 15
RO - Romania 15
TW - Taiwan 14
VE - Venezuela 14
EU - Europa 13
KG - Kirghizistan 13
LT - Lituania 13
GR - Grecia 12
KE - Kenya 12
EG - Egitto 11
IR - Iran 11
JO - Giordania 11
CR - Costa Rica 10
HN - Honduras 8
NP - Nepal 8
SV - El Salvador 8
TN - Tunisia 8
AL - Albania 7
BO - Bolivia 7
PY - Paraguay 7
TH - Thailandia 7
TT - Trinidad e Tobago 7
HR - Croazia 6
PR - Porto Rico 6
PT - Portogallo 6
SN - Senegal 6
UY - Uruguay 6
AZ - Azerbaigian 5
DZ - Algeria 5
KZ - Kazakistan 5
NO - Norvegia 5
DK - Danimarca 4
DO - Repubblica Dominicana 4
GT - Guatemala 4
RS - Serbia 4
CI - Costa d'Avorio 3
DM - Dominica 3
GE - Georgia 3
MD - Moldavia 3
NI - Nicaragua 3
NZ - Nuova Zelanda 3
OM - Oman 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AW - Aruba 2
BB - Barbados 2
BG - Bulgaria 2
BS - Bahamas 2
ET - Etiopia 2
GP - Guadalupe 2
LB - Libano 2
LK - Sri Lanka 2
LV - Lettonia 2
ML - Mali 2
Totale 98.439
Salva come PNG Salva come JPEG
Città #
Woodbridge 22.801
Wilmington 19.427
Houston 17.691
Kraków 3.276
Fairfield 2.304
Ann Arbor 1.833
Singapore 1.718
Ashburn 1.482
Chandler 1.206
Seattle 929
Jacksonville 914
San Jose 874
Cambridge 797
Dublin 662
Hong Kong 645
Beijing 569
New York 514
Medford 504
Dearborn 493
Council Bluffs 433
The Dalles 292
Rome 290
Santa Clara 288
Los Angeles 240
Lawrence 232
Ho Chi Minh City 180
Tokyo 152
Moscow 142
Hanoi 140
Lauterbourg 131
Menlo Park 131
Buffalo 129
Boardman 118
San Diego 114
Mülheim 104
Helsinki 101
Dallas 95
São Paulo 95
Zhengzhou 94
Milan 89
Munich 65
Brussels 59
Chicago 58
Mountain View 56
Norwalk 56
London 53
Nuremberg 52
Montreal 50
Warsaw 48
Phoenix 46
Orem 44
Atlanta 43
Rio de Janeiro 43
Daejeon 42
Falls Church 42
Brooklyn 41
Redwood City 41
Toronto 41
Guangzhou 40
Redondo Beach 39
Shanghai 38
University Park 36
San Francisco 34
Verona 34
Denver 32
North Bergen 30
Belo Horizonte 29
Mexico City 29
Jakarta 28
San Mateo 28
Hefei 27
Nanjing 27
Da Nang 26
Johannesburg 26
Kunming 26
Chennai 25
Washington 25
Boston 23
Frankfurt am Main 23
Haiphong 22
Stockholm 22
Brasília 21
Hangzhou 21
Poplar 21
Vienna 21
Amsterdam 20
Naples 20
Nürnberg 19
Baghdad 18
Creede 17
North Charleston 17
Palo Alto 17
Philadelphia 17
Seoul 17
Columbus 16
Manchester 16
Mumbai 16
Salt Lake City 16
Saint Petersburg 15
Campinas 14
Totale 84.117
Salva come PNG Salva come JPEG
Nome #
PVA engineered microcapsules for targeted delivery of camptothecin to HeLa cells 639
Molecular Dynamics Simulation of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha: evidence of a dynamical relationship between helices 3 and 5. 591
A natural anticancer agent thaspine targets human topoisomerase IB 573
DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family 554
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 549
Gene expression profile study in CFTR mutated bronchial cell lines 537
10-undecanhydroxamic acid, a hydroxamate derivative of the undecanoic acid, has strong antimicrobial activity through a mechanism that limits iron availability 535
A Simple and Fast Semiautomatic Procedure for the Atomistic Modeling of Complex DNA Polyhedra 530
Structural-dynamical investigation of the ZnuA histidine-rich loop: involvement in zinc management and transport 529
A structural modeling approach for the understanding of initiation and elongation of ALS-linked superoxide dismutase fibrils 524
Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase 523
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 523
In vitro analysis of pyrogenicity and cytotoxicity profiles of flex sensors to be used to sense human joint postures 521
Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B 520
Functional and crystallographic characterization of Salmonella typhimurium Cu,Zn superoxide dismutase coded by the sodCI virulence gene 517
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 510
Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy 509
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 509
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I 508
New hints on the pH-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach 507
Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation. 507
Design of a novel LOX-1 receptor antagonist mimicking the natural substrate 507
Simulative and experimental characterization of a pH-dependent clamp-like DNA triple-helix nanoswitch 507
Interaction between natural compounds and human topoisomerase I 506
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 503
Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: A spectroscopic and molecular modelling study 502
The open state of human topoisomerase I as probed by molecular dynamics simulation 501
A model for the incorporation of the metal from the copper chaperone CCS to Cu,Zn superoxide dismutase 501
Adsorption of the cysteine–tryptophan dipeptide at the Au(110)/liquid interface studied using reflection anisotropy spectroscopy 500
Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages 500
Dynamic changes in gene expression profiles of 22q11 and related orthologous genes during mouse development 499
Toward the engineering of a super efficient enzyme 498
Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies 498
Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase 495
Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain 493
Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity. 493
Anion size modulates the structure of the a state of cytochrome c 492
Solvent dependency of the UV-Vis spectrum of indenoisoquinolines: role of keto-oxygens as polarity interaction probes. 492
Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage 492
Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1 491
X-ray absorption investigation of a unique protein domain able to bind both copper(I) and copper(II) at adjacent sites of the N-terminus of Haemophilus ducreyi Cu,Zn superoxide dismutase 490
Role of human topoisomerase IB on ionizing radiation induced damage. 490
Thermophilicity of wild type and mutant cold shock proteins by molecular dynamics simulation. 489
A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 489
Formation of a molten-globule-like state of cytochrome c induced by high concentrations of glycerol 487
Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin. 486
The Essential Dynamics of Cu,Zn superoxide dismutase: Suggestion of intersubunit communication 486
Molecular dynamics simulations of the Trp repressor–DNA complex and the AV77 mutant 485
Structure and stability of the insulin dimer investigated by molecular dynamics simulation 483
Solvent Effects on the Valence UV-Vis Absorption Spectra of Topotecan Anticancer Drug in Aqueous Solution at Room Temperature: A Nanoseconds Time-scale TD-DFT/MD Computational Study 481
Virtual Screening for the Development of Dual-Inhibitors Targeting Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 480
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 477
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 477
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 477
An electrochemical multienzymatic biosensor for determination of cholesterol 476
Molecular mechanism of statin-mediated LOX-1 inhibition 476
Effect of temperature and hydration on protein fluctuations: molecular dynamics simulation of Cu, Zn superoxide dismutase at six different temperatures. Comparison with neutron scattering data 476
Cells microenvironment engineering multiphoton absorption for muscle regeneration optimization 474
Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene 474
Beta-bungarotoxin-mediated liposome fusion: spectroscopic characterization by fluorescence and ESR. 473
Oxidation of L-Thiols in the Presence of Iron(III) Complex Ions Anchored to Asymmetric Polymers. A Kinetic and Conformational Investigation 473
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 472
Structure of nano-Scale Truncated Octahedral DNA Cages: Variation of Single-stranded Linker Regions and Influence on Assembly Yields. 472
Influence of the single-strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano-cage family 472
Single mutation induces a metal-dependent subunit association in dimeric Cu,Zn superoxide dismutase 471
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 471
Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines 471
Assignment of UV-vis spectrum of (3,3')-diindolylmethane, a Leishmania donovani topoisomerase IB inhibitor and a candidate DNA minor groove binder. 470
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 470
Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling 470
Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface. 469
Simulative Analysis of a Truncated Octahedral DNA Nanocage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability 467
Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences. 467
Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant. 466
Valproic acid induces neuroendocrine differentiation and UGT2B7 up-regulation in human prostate carcinoma cell line 465
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 465
Oxidovanadium(IV) complexes with chrysin and silibinin: Anticancer activity and mechanisms of action in a human colon adenocarcinoma model 465
MD simulations of papillomavirus DNA-E2 protein complexes hints at a protein structural code for DNA deformation. 464
An electrostatic enzyme-substrate recognition: the case of Cu,Zn superoxide dismutase 464
An amber compatible molecular mechanics force field for the anticancer drug topotecan 463
Targeting Tumor Cells through Chitosan-Folate Modified Microcapsules Loaded with Camptothecin 461
Calculation of local electric fields in Shark Cu,Zn superoxide dismutase 461
A Small Sided Game session effects salivary metabolic levels in young soccer players 461
The mitochondrial oxoglutarate carrier: Structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling 460
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 459
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 459
Reduced sensitivity of O2 transport to allosteric effectors and temperature in loggerhead sea turtle hemoglobin: functional and spectroscopic study 459
The Potential of Nucleic Acid-Based Nanoparticles for Biomedical Application 459
Characterization of a novel CYP2C9 gene mutation and structural bioinformatic protein analysis in a warfarin hypersensitive patient 459
Zinc ion coordination as a modulating factor of the ZnuA histidine-rich loop flexibility: a molecular modeling and fluorescence spectroscopy study 458
Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol 458
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 457
Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and ruminant hemoglobins: a comparative study 457
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 456
The heme-containing N-fragment (residues 1-56) of cytochrome c is a bis-histidine functional system 455
Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages 455
Geometrical constraints limiting the poly(ADP-ribose) conformation investigated by molecular dynamics simulation. 454
Role of the helix capping in the stability of the mouse prion (180-213) segment: investigation through molecular dynamics simulations 454
A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function 452
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 451
Totale 48.823
Salva come PNG Salva come JPEG
Categoria #
all - tutte 213.830
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 213.830
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.488 0 230 272 175 65 208 125 79 272 207 157 698
2022/20233.179 315 219 64 438 310 753 286 201 300 6 206 81
2023/20241.221 137 40 65 47 118 456 25 47 17 16 17 236
2024/20255.527 194 1.003 507 263 294 403 396 323 513 510 616 505
2025/20268.709 735 371 1.032 762 708 348 1.029 1.180 875 960 397 312
2026/2027765 414 351 0 0 0 0 0 0 0 0 0 0
Totale 99.143