IRIS
DESIDERI, ALESSANDRO
 Distribuzione geografica
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Continente #
NA - Nord America 80.730
EU - Europa 11.479
AS - Asia 7.490
SA - Sud America 1.250
Continente sconosciuto - Info sul continente non disponibili 688
AF - Africa 124
OC - Oceania 21
Totale 101.782
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Nazione #
US - Stati Uniti d'America 80.318
SG - Singapore 3.543
PL - Polonia 3.331
FR - Francia 1.695
CN - Cina 1.427
DE - Germania 1.086
BR - Brasile 1.030
UA - Ucraina 1.028
RU - Federazione Russa 930
IT - Italia 870
SE - Svezia 700
IE - Irlanda 674
HK - Hong Kong 653
VN - Vietnam 618
GB - Regno Unito 472
FI - Finlandia 323
KR - Corea 321
BD - Bangladesh 242
CA - Canada 197
JP - Giappone 185
IN - India 118
MX - Messico 78
BE - Belgio 64
AR - Argentina 62
NL - Olanda 57
ID - Indonesia 56
ES - Italia 52
AT - Austria 48
IQ - Iraq 47
TR - Turchia 45
CO - Colombia 44
ZA - Sudafrica 44
EC - Ecuador 37
LT - Lituania 31
JM - Giamaica 26
VE - Venezuela 22
CR - Costa Rica 21
IL - Israele 21
PH - Filippine 20
SA - Arabia Saudita 20
PK - Pakistan 19
AE - Emirati Arabi Uniti 17
CH - Svizzera 17
CL - Cile 17
CZ - Repubblica Ceca 17
MY - Malesia 17
UZ - Uzbekistan 17
AU - Australia 16
MA - Marocco 15
PE - Perù 15
RO - Romania 15
TW - Taiwan 14
EU - Europa 13
KE - Kenya 13
KG - Kirghizistan 13
NI - Nicaragua 13
GR - Grecia 12
HN - Honduras 12
TH - Thailandia 12
TT - Trinidad e Tobago 12
EG - Egitto 11
IR - Iran 11
JO - Giordania 11
SV - El Salvador 11
NP - Nepal 9
PR - Porto Rico 9
GT - Guatemala 8
TN - Tunisia 8
UY - Uruguay 8
AL - Albania 7
BO - Bolivia 7
DK - Danimarca 7
KZ - Kazakistan 7
PY - Paraguay 7
HR - Croazia 6
NO - Norvegia 6
PT - Portogallo 6
SN - Senegal 6
AZ - Azerbaigian 5
BB - Barbados 5
DZ - Algeria 5
EE - Estonia 5
DO - Repubblica Dominicana 4
RS - Serbia 4
CI - Costa d'Avorio 3
DM - Dominica 3
GE - Georgia 3
GP - Guadalupe 3
LB - Libano 3
MD - Moldavia 3
NG - Nigeria 3
NZ - Nuova Zelanda 3
OM - Oman 3
PA - Panama 3
PS - Palestinian Territory 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AW - Aruba 2
BG - Bulgaria 2
BN - Brunei Darussalam 2
Totale 101.068
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Città #
Woodbridge 22.801
Wilmington 19.429
Houston 17.698
Kraków 3.276
Fairfield 2.304
Ashburn 1.996
Ann Arbor 1.833
Singapore 1.719
Chandler 1.206
San Jose 1.082
Seattle 931
Jacksonville 916
Cambridge 797
Dublin 664
Hong Kong 645
Beijing 570
New York 534
Medford 504
Dearborn 493
Council Bluffs 476
Santa Clara 311
Rome 298
The Dalles 297
Los Angeles 262
Lawrence 233
Ho Chi Minh City 184
Tokyo 154
Moscow 142
Hanoi 141
Buffalo 137
Lauterbourg 131
Menlo Park 131
Boardman 125
São Paulo 116
San Diego 115
Dallas 105
Mülheim 104
Helsinki 101
Zhengzhou 94
Milan 92
Chicago 66
Munich 65
Atlanta 60
Brussels 59
Montreal 59
Denver 57
Norwalk 57
Mountain View 56
London 53
North Bergen 53
Nuremberg 52
Toronto 52
Phoenix 48
Warsaw 48
Brooklyn 47
Orem 45
Falls Church 43
Rio de Janeiro 43
Daejeon 42
Redwood City 41
Guangzhou 40
Redondo Beach 39
San Francisco 38
Shanghai 38
University Park 36
Verona 34
Belo Horizonte 29
Mexico City 29
Washington 29
Jakarta 28
San Mateo 28
Brasília 27
Hefei 27
Nanjing 27
Da Nang 26
Johannesburg 26
Kunming 26
Chennai 25
Naples 24
Boston 23
Frankfurt am Main 23
Philadelphia 23
Haiphong 22
Stockholm 22
Amsterdam 21
Hangzhou 21
Miami 21
Poplar 21
Vienna 21
Vilnius 21
Kingston 19
Nürnberg 19
Baghdad 18
Columbus 18
Seoul 18
Creede 17
Guayaquil 17
Las Vegas 17
North Charleston 17
Palo Alto 17
Totale 85.185
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Nome #
PVA engineered microcapsules for targeted delivery of camptothecin to HeLa cells 651
Molecular Dynamics Simulation of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha: evidence of a dynamical relationship between helices 3 and 5. 601
A natural anticancer agent thaspine targets human topoisomerase IB 587
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 562
DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family 560
10-undecanhydroxamic acid, a hydroxamate derivative of the undecanoic acid, has strong antimicrobial activity through a mechanism that limits iron availability 556
A Simple and Fast Semiautomatic Procedure for the Atomistic Modeling of Complex DNA Polyhedra 546
Gene expression profile study in CFTR mutated bronchial cell lines 545
A structural modeling approach for the understanding of initiation and elongation of ALS-linked superoxide dismutase fibrils 542
Structural-dynamical investigation of the ZnuA histidine-rich loop: involvement in zinc management and transport 537
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 535
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 533
Design of a novel LOX-1 receptor antagonist mimicking the natural substrate 531
In vitro analysis of pyrogenicity and cytotoxicity profiles of flex sensors to be used to sense human joint postures 530
Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase 527
Functional and crystallographic characterization of Salmonella typhimurium Cu,Zn superoxide dismutase coded by the sodCI virulence gene 526
Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy 526
Simulative and experimental characterization of a pH-dependent clamp-like DNA triple-helix nanoswitch 526
Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B 526
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 521
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 519
Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation. 517
Interaction between natural compounds and human topoisomerase I 516
New hints on the pH-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach 515
Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage 515
Dynamic changes in gene expression profiles of 22q11 and related orthologous genes during mouse development 514
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I 514
The open state of human topoisomerase I as probed by molecular dynamics simulation 513
Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: A spectroscopic and molecular modelling study 513
A model for the incorporation of the metal from the copper chaperone CCS to Cu,Zn superoxide dismutase 513
Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages 511
Adsorption of the cysteine–tryptophan dipeptide at the Au(110)/liquid interface studied using reflection anisotropy spectroscopy 510
Toward the engineering of a super efficient enzyme 508
A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 507
Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies 506
X-ray absorption investigation of a unique protein domain able to bind both copper(I) and copper(II) at adjacent sites of the N-terminus of Haemophilus ducreyi Cu,Zn superoxide dismutase 505
Anion size modulates the structure of the a state of cytochrome c 503
Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain 503
Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase 502
Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1 502
Formation of a molten-globule-like state of cytochrome c induced by high concentrations of glycerol 501
Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity. 501
Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin. 500
Thermophilicity of wild type and mutant cold shock proteins by molecular dynamics simulation. 499
Solvent dependency of the UV-Vis spectrum of indenoisoquinolines: role of keto-oxygens as polarity interaction probes. 498
Role of human topoisomerase IB on ionizing radiation induced damage. 498
Virtual Screening for the Development of Dual-Inhibitors Targeting Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 497
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 496
Molecular dynamics simulations of the Trp repressor–DNA complex and the AV77 mutant 496
Structure and stability of the insulin dimer investigated by molecular dynamics simulation 495
The Essential Dynamics of Cu,Zn superoxide dismutase: Suggestion of intersubunit communication 492
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 490
Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene 489
Solvent Effects on the Valence UV-Vis Absorption Spectra of Topotecan Anticancer Drug in Aqueous Solution at Room Temperature: A Nanoseconds Time-scale TD-DFT/MD Computational Study 488
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 487
Cells microenvironment engineering multiphoton absorption for muscle regeneration optimization 487
An electrochemical multienzymatic biosensor for determination of cholesterol 486
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 486
Structure of nano-Scale Truncated Octahedral DNA Cages: Variation of Single-stranded Linker Regions and Influence on Assembly Yields. 486
Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines 485
Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant. 484
Beta-bungarotoxin-mediated liposome fusion: spectroscopic characterization by fluorescence and ESR. 484
Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences. 483
Influence of the single-strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano-cage family 483
Effect of temperature and hydration on protein fluctuations: molecular dynamics simulation of Cu, Zn superoxide dismutase at six different temperatures. Comparison with neutron scattering data 483
Oxidation of L-Thiols in the Presence of Iron(III) Complex Ions Anchored to Asymmetric Polymers. A Kinetic and Conformational Investigation 482
Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface. 481
Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling 481
Molecular mechanism of statin-mediated LOX-1 inhibition 481
Oxidovanadium(IV) complexes with chrysin and silibinin: Anticancer activity and mechanisms of action in a human colon adenocarcinoma model 481
Valproic acid induces neuroendocrine differentiation and UGT2B7 up-regulation in human prostate carcinoma cell line 479
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 479
Single mutation induces a metal-dependent subunit association in dimeric Cu,Zn superoxide dismutase 478
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 478
Assignment of UV-vis spectrum of (3,3')-diindolylmethane, a Leishmania donovani topoisomerase IB inhibitor and a candidate DNA minor groove binder. 477
Simulative Analysis of a Truncated Octahedral DNA Nanocage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability 476
Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages 476
MD simulations of papillomavirus DNA-E2 protein complexes hints at a protein structural code for DNA deformation. 474
Targeting Tumor Cells through Chitosan-Folate Modified Microcapsules Loaded with Camptothecin 474
A Small Sided Game session effects salivary metabolic levels in young soccer players 474
Impaired copper binding by the H46R mutant of human Cu,Zn superoxide dismutase, involved in amyotrophic lateral sclerosis 472
An amber compatible molecular mechanics force field for the anticancer drug topotecan 472
Zinc ion coordination as a modulating factor of the ZnuA histidine-rich loop flexibility: a molecular modeling and fluorescence spectroscopy study 472
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 472
Metal uptake of recombinant cambialistic superoxide dismutase from Propionitbacterium shermanii is affected by growth conditions of host Escherichia coli cells 471
An electrostatic enzyme-substrate recognition: the case of Cu,Zn superoxide dismutase 471
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 471
Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol 470
The mitochondrial oxoglutarate carrier: Structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling 468
Calculation of local electric fields in Shark Cu,Zn superoxide dismutase 468
Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and ruminant hemoglobins: a comparative study 465
Characterization of a novel CYP2C9 gene mutation and structural bioinformatic protein analysis in a warfarin hypersensitive patient 465
Reduced sensitivity of O2 transport to allosteric effectors and temperature in loggerhead sea turtle hemoglobin: functional and spectroscopic study 463
Geometrical constraints limiting the poly(ADP-ribose) conformation investigated by molecular dynamics simulation. 463
The Potential of Nucleic Acid-Based Nanoparticles for Biomedical Application 463
Electrostatic recognition in redox copper proteins: a 1H NMR study of the protonation behavior of His 19 in oxidized and reduced Cu,Zn superoxide dismutase 462
A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function 462
The heme-containing N-fragment (residues 1-56) of cytochrome c is a bis-histidine functional system 461
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 460
Real-time detection of TDP1 activity using a fluorophore-quencher coupled DNA-biosensor 459
Totale 49.949
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Categoria #
all - tutte 221.641
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 221.641
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.986 0 0 0 175 65 208 125 79 272 207 157 698
2022/20233.179 315 219 64 438 310 753 286 201 300 6 206 81
2023/20241.221 137 40 65 47 118 456 25 47 17 16 17 236
2024/20255.527 194 1.003 507 263 294 403 396 323 513 510 616 505
2025/20268.709 735 371 1.032 762 708 348 1.029 1.180 875 960 397 312
2026/20273.404 414 444 1.655 891 0 0 0 0 0 0 0 0
Totale 101.782