IRIS
DESIDERI, ALESSANDRO
 Distribuzione geografica
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Continente #
NA - Nord America 73.716
EU - Europa 9.811
AS - Asia 2.152
SA - Sud America 25
Continente sconosciuto - Info sul continente non disponibili 15
OC - Oceania 10
AF - Africa 3
Totale 85.732
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Nazione #
US - Stati Uniti d'America 73.685
PL - Polonia 3.283
FR - Francia 1.532
SG - Singapore 1.064
UA - Ucraina 1.005
DE - Germania 961
IE - Irlanda 665
SE - Svezia 660
CN - Cina 652
IT - Italia 535
RU - Federazione Russa 398
GB - Regno Unito 333
KR - Corea 311
FI - Finlandia 253
BE - Belgio 60
AT - Austria 28
IN - India 27
JP - Giappone 27
CA - Canada 25
NL - Olanda 23
BR - Brasile 18
CZ - Repubblica Ceca 13
ES - Italia 13
EU - Europa 13
KG - Kirghizistan 12
RO - Romania 12
CH - Svizzera 11
IL - Israele 11
HK - Hong Kong 8
ID - Indonesia 8
AU - Australia 7
GR - Grecia 7
UZ - Uzbekistan 6
VN - Vietnam 6
CL - Cile 5
HR - Croazia 4
IR - Iran 4
BD - Bangladesh 3
DM - Dominica 3
NO - Norvegia 3
NZ - Nuova Zelanda 3
A2 - ???statistics.table.value.countryCode.A2??? 2
DK - Danimarca 2
MD - Moldavia 2
MX - Messico 2
MY - Malesia 2
PH - Filippine 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TR - Turchia 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
CR - Costa Rica 1
EC - Ecuador 1
EG - Egitto 1
HU - Ungheria 1
IQ - Iraq 1
IS - Islanda 1
LK - Sri Lanka 1
LT - Lituania 1
PE - Perù 1
PK - Pakistan 1
SA - Arabia Saudita 1
SC - Seychelles 1
ZA - Sudafrica 1
Totale 85.732
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Città #
Woodbridge 22.799
Wilmington 19.423
Houston 17.673
Kraków 3.276
Fairfield 2.303
Ann Arbor 1.833
Chandler 1.206
Ashburn 1.074
Seattle 917
Jacksonville 909
Singapore 906
Cambridge 792
Dublin 657
Medford 503
Dearborn 493
New York 392
Beijing 269
Rome 234
Lawrence 232
Santa Clara 210
Menlo Park 131
San Diego 113
Boardman 111
Mülheim 104
Moscow 96
Zhengzhou 93
Milan 61
Mountain View 56
Norwalk 56
Brussels 55
Helsinki 43
Daejeon 42
Falls Church 42
Redwood City 41
Council Bluffs 38
University Park 36
Verona 34
London 33
Guangzhou 31
Nuremberg 28
Shanghai 28
Hefei 27
Nanjing 27
San Mateo 27
Kunming 25
Munich 21
Los Angeles 19
Nürnberg 19
Toronto 19
Creede 17
Palo Alto 17
Saint Petersburg 15
San Francisco 15
Nanchang 14
Phoenix 14
Hangzhou 12
Indiana 12
Seoul 12
São Paulo 12
Pune 11
Vienna 11
Detroit 9
Fuzhou 9
Prescot 9
Scottsdale 9
Tappahannock 9
Hebei 8
Hounslow 8
Kilburn 8
Atlanta 7
Hanover 7
Hong Kong 7
Brno 6
Chicago 6
Engelhard 6
Kendall Park 6
Madrid 6
Nanning 6
Pomezia 6
Portland 6
Shenyang 6
Turin 6
Auburn Hills 5
Chengdu 5
Jinan 5
Mcallen 5
Napoli 5
Washington 5
Zurich 5
Amsterdam 4
Changsha 4
Del Norte 4
Espoo 4
Fiuggi 4
Iasi 4
La Canada Flintridge 4
Montréal 4
New Bedfont 4
Padova 4
Redmond 4
Totale 77.948
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Nome #
DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family 504
Gene expression profile study in CFTR mutated bronchial cell lines 496
A natural anticancer agent thaspine targets human topoisomerase IB 486
Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography 477
Mutation of Lys-120 and Lys-134 drastically reduces the catalytic rate of Cu,Zn superoxide dismutase 474
Efficacy of a Binuclear Cyclopalladated Compound Therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on Topoisomerase 1B 473
Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy 468
In vitro analysis of pyrogenicity and cytotoxicity profiles of flex sensors to be used to sense human joint postures 468
A Simple and Fast Semiautomatic Procedure for the Atomistic Modeling of Complex DNA Polyhedra 468
Molecular dynamics of the DNA-binding domain of the papillomavirus E2 transcriptional regulator uncover differential properties for DNA target accommodation. 464
Mapping the copper ligands of Cu,Zn superoxide dismutase by nuclear Overhauser enhancement of the isotropically shifted 1H-NMR lines of the Cu,Co derivative 461
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I 461
Structural-dynamical investigation of the ZnuA histidine-rich loop: involvement in zinc management and transport 459
The Essential Dynamics of Cu,Zn superoxide dismutase: Suggestion of intersubunit communication 458
Active site copper and zinc ions modulate the quaternary structure of prokaryotic Cu,Zn superoxide dismutase 458
Interaction between natural compounds and human topoisomerase I 457
Comparative simulative analysis of single and double stranded truncated octahedral DNA nanocages 453
New hints on the pH-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach 451
Role of human topoisomerase IB on ionizing radiation induced damage. 450
Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: A spectroscopic and molecular modelling study 447
Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies 447
Solvent dependency of the UV-Vis spectrum of indenoisoquinolines: role of keto-oxygens as polarity interaction probes. 447
Formation of a molten-globule-like state of cytochrome c induced by high concentrations of glycerol 446
Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1 446
Functional analysis and molecular dynamics simulation of LOX-1 K167N polymorphism reveal alteration of receptor activity. 445
Three-dimensional structure of Xenopus laevis Cu,Zn superoxide dismutase b determined by X-ray crystallography at 1.5 A resolution 445
Toward the engineering of a super efficient enzyme 444
Effect of temperature and hydration on protein fluctuations: molecular dynamics simulation of Cu, Zn superoxide dismutase at six different temperatures. Comparison with neutron scattering data 443
Two-dimensional NMR assignment of hyperfine-shifted resonances of very fast relaxing metal binding sites of proteins by NOE spectroscopy. The case of Cu, Co superoxide dismutase 442
Structure and stability of the insulin dimer investigated by molecular dynamics simulation 442
Thermophilicity of wild type and mutant cold shock proteins by molecular dynamics simulation. 441
10-undecanhydroxamic acid, a hydroxamate derivative of the undecanoic acid, has strong antimicrobial activity through a mechanism that limits iron availability 440
Dynamic changes in gene expression profiles of 22q11 and related orthologous genes during mouse development 440
NMR evidence for perturbation of the copper coordination sphere upon chemical modification of arginine 141 in bovine Cu,Zn superoxide dismutase 439
Simulative and experimental characterization of a pH-dependent clamp-like DNA triple-helix nanoswitch 439
Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 437
Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene 437
Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin. 436
Functional and crystallographic characterization of Salmonella typhimurium Cu,Zn superoxide dismutase coded by the sodCI virulence gene 435
Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain 434
Molecular dynamics simulations of the Trp repressor–DNA complex and the AV77 mutant 434
X-ray absorption investigation of a unique protein domain able to bind both copper(I) and copper(II) at adjacent sites of the N-terminus of Haemophilus ducreyi Cu,Zn superoxide dismutase 434
PVA engineered microcapsules for targeted delivery of camptothecin to HeLa cells 432
A structural modeling approach for the understanding of initiation and elongation of ALS-linked superoxide dismutase fibrils 432
A model for the incorporation of the metal from the copper chaperone CCS to Cu,Zn superoxide dismutase 432
Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase 430
Adsorption of the cysteine–tryptophan dipeptide at the Au(110)/liquid interface studied using reflection anisotropy spectroscopy 429
Virtual Screening for the Development of Dual-Inhibitors Targeting Topoisomerase IB and Tyrosyl-DNA Phosphodiesterase 1 429
Evolutionary conservativeness of electric field in the Cu,Zn superoxide dismutase active site. Evidence for coordinated mutations of charged aminoacid residues 429
Anion size modulates the structure of the a state of cytochrome c 428
Effect of Lys->Arg mutation on the thermal stability of Cu,Zn superoxide dismutase: Influence on the monomer-dimer equilibrium 428
Molecular mechanism of statin-mediated LOX-1 inhibition 428
Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling 427
Design of a novel LOX-1 receptor antagonist mimicking the natural substrate 427
Access of anions and electrostatic interactions in the active site of Cu,Zn superoxide dismutase. 426
Experimental and simulative dissociation of dimeric Cu,Zn superoxide dismutase doubly mutated at the intersubunit surface. 424
The Potential of Nucleic Acid-Based Nanoparticles for Biomedical Application 424
Single mutation induces a metal-dependent subunit association in dimeric Cu,Zn superoxide dismutase 423
The mitochondrial oxoglutarate carrier: Structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling 423
Beta-bungarotoxin-mediated liposome fusion: spectroscopic characterization by fluorescence and ESR. 423
The open state of human topoisomerase I as probed by molecular dynamics simulation 422
null 422
Role of the helix capping in the stability of the mouse prion (180-213) segment: investigation through molecular dynamics simulations 422
Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol 421
Valproic acid induces neuroendocrine differentiation and UGT2B7 up-regulation in human prostate carcinoma cell line 420
Role of the electrostatic loop charged residues in Cu,Zn superoxide dismutase 420
MD simulations of papillomavirus DNA-E2 protein complexes hints at a protein structural code for DNA deformation. 420
Simulative Analysis of a Truncated Octahedral DNA Nanocage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability 420
An electrochemical multienzymatic biosensor for determination of cholesterol 418
Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant. 418
Structure of nano-Scale Truncated Octahedral DNA Cages: Variation of Single-stranded Linker Regions and Influence on Assembly Yields. 417
Is the activity-linked electrostatic gradient of bovine Cu/Zn superoxide dismutase conserved in homologous enzymes irrespective of the number and distribution of charges? 417
Cells microenvironment engineering multiphoton absorption for muscle regeneration optimization 417
Molecular dynamics simulations of Cu,Zn superoxide dismutase: effect of temperature on dimer asymmetry 416
The heme-containing N-fragment (residues 1-56) of cytochrome c is a bis-histidine functional system 414
Thr729 in human topoisomerase I modulates anti-cancer drug resistance by altering protein domain communications as suggested by molecular dynamics simulations 414
Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase 414
Influence of the single-strand linker composition on the structural/dynamical properties of a truncated octahedral DNA nano-cage family 413
Cu,Zn superoxide dismutase in prokaryotes and eukaryotes. 412
Crystallographic characterization and three-dimensional model of yeast Cu,Zn superoxide dismutase 412
Reduced sensitivity of O2 transport to allosteric effectors and temperature in loggerhead sea turtle hemoglobin: functional and spectroscopic study 410
Targeting Tumor Cells through Chitosan-Folate Modified Microcapsules Loaded with Camptothecin 410
Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines 409
Oxidovanadium(IV) complexes with chrysin and silibinin: Anticancer activity and mechanisms of action in a human colon adenocarcinoma model 409
An amber compatible molecular mechanics force field for the anticancer drug topotecan 408
A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 408
Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification 408
Superoxide Dismutase Kinetics 408
Characterization of a novel CYP2C9 gene mutation and structural bioinformatic protein analysis in a warfarin hypersensitive patient 408
Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and ruminant hemoglobins: a comparative study 407
Effect of Val73->Trp mutation on the reaction of ''cambialistic'' superoxide dismutase from Propionibacterium shermanii with hydrogen peroxide 406
Calculation of local electric fields in Shark Cu,Zn superoxide dismutase 406
Inhibition of glutathione transferase pi from human placenta by 1-chloro-2,4-dinitrobenzene occurs because of covalent reaction with cysteine 47 404
Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect 404
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Crystal structure solution and refinement of the semisynthetic cobalt -substituted bovine erythrocyte superoxide dismutase at 2.0Å resolution 404
Superefficient Enzymes 404
Importance of V3 loop flexibility and net charge in the context of co-receptor recognition. A molecular dynamics study on HIV gp120 403
Receptor-Mediated Entry of Pristine Octahedral DNA Nanocages in Mammalian Cells 402
Fe-heme structure in Cu, Zn superoxide dismutase from Haemophilus ducreyi by X-ray absorption spectroscopy 401
Totale 43.192
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Categoria #
all - tutte 158.107
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 158.107
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202014.583 0 0 0 0 1.800 2.277 1.951 2.052 1.917 1.743 1.382 1.461
2020/202112.111 1.389 1.450 1.302 1.547 1.233 1.255 1.490 1.167 296 328 481 173
2021/20222.616 128 230 272 175 65 208 125 79 272 207 157 698
2022/20233.179 315 219 64 438 310 753 286 201 300 6 206 81
2023/20241.221 137 40 65 47 118 456 25 47 17 16 17 236
2024/20252.230 194 1.003 507 263 263 0 0 0 0 0 0 0
Totale 86.372