IRIS
GRAZIANI, GRAZIA
 Distribuzione geografica
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Continente #
NA - Nord America 76.216
EU - Europa 6.966
AS - Asia 1.623
SA - Sud America 39
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 12
AF - Africa 10
Totale 84.879
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Nazione #
US - Stati Uniti d'America 76.153
IT - Italia 1.794
UA - Ucraina 1.145
DE - Germania 1.082
CN - Cina 853
IE - Irlanda 741
FR - Francia 590
SE - Svezia 414
GB - Regno Unito 316
PL - Polonia 313
KR - Corea 292
SG - Singapore 270
FI - Finlandia 238
RU - Federazione Russa 180
JP - Giappone 62
CA - Canada 43
IN - India 43
CZ - Repubblica Ceca 34
BE - Belgio 25
NL - Olanda 24
IR - Iran 22
BR - Brasile 19
MX - Messico 18
VN - Vietnam 17
EU - Europa 12
HK - Hong Kong 12
KG - Kirghizistan 12
IL - Israele 11
AT - Austria 10
AU - Australia 10
AL - Albania 8
BG - Bulgaria 8
CH - Svizzera 8
CO - Colombia 8
CL - Cile 7
ES - Italia 7
PH - Filippine 7
MK - Macedonia 5
DK - Danimarca 4
ID - Indonesia 4
PT - Portogallo 4
RO - Romania 4
TR - Turchia 4
TW - Taiwan 4
AR - Argentina 3
EG - Egitto 3
LU - Lussemburgo 3
AE - Emirati Arabi Uniti 2
GR - Grecia 2
HU - Ungheria 2
LT - Lituania 2
MA - Marocco 2
MW - Malawi 2
MY - Malesia 2
NZ - Nuova Zelanda 2
A1 - Anonimo 1
BD - Bangladesh 1
CY - Cipro 1
DZ - Algeria 1
EC - Ecuador 1
GT - Guatemala 1
IQ - Iraq 1
JM - Giamaica 1
MD - Moldavia 1
MU - Mauritius 1
NO - Norvegia 1
PE - Perù 1
PS - Palestinian Territory 1
SA - Arabia Saudita 1
SC - Seychelles 1
SI - Slovenia 1
UZ - Uzbekistan 1
Totale 84.879
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Città #
Woodbridge 24.329
Wilmington 19.893
Houston 19.875
Ann Arbor 2.050
Fairfield 1.618
Chandler 1.044
Jacksonville 1.015
Ashburn 953
Dublin 688
Seattle 639
Cambridge 549
Medford 533
Dearborn 451
New York 441
Beijing 393
Rome 344
Kraków 301
Lawrence 255
Mülheim 176
Singapore 166
Milan 143
Menlo Park 127
Zhengzhou 92
San Diego 90
Moscow 86
Boardman 70
Mountain View 56
Redwood City 54
University Park 53
Falls Church 47
Nanjing 40
Norwalk 40
Palo Alto 40
Hefei 38
San Mateo 37
Guangzhou 34
Verona 30
London 29
Shanghai 27
Civitavecchia 26
Hangzhou 26
Phoenix 25
Brussels 24
Naples 24
Kunming 21
Prague 21
Engelhard 20
Helsinki 20
Pisa 20
Saint Petersburg 20
Seoul 19
Toronto 19
Catania 18
Ottawa 18
Los Angeles 17
Del Norte 16
Nanchang 15
Napoli 15
Nuremberg 15
Pune 15
Turin 15
Dong Ket 14
Florence 14
Fuzhou 14
Jinan 14
Nürnberg 14
Indiana 13
Kansas City 12
Palermo 12
Bari 11
Brno 11
Hebei 11
Redmond 11
Chicago 10
Kilburn 10
Munich 10
Washington 10
Casalnuovo Di Napoli 9
Chengdu 9
Council Bluffs 9
San Jose 9
Bologna 8
Center 8
Creede 8
Shenyang 8
Warsaw 8
Auburn Hills 7
Changsha 7
Hong Kong 7
La Veta 7
Padova 7
Pavia 7
Pioppi 7
Salt Lake City 7
Santa Clara 7
Segrate 7
Arnesano 6
Cattolica 6
Gragnano 6
Paris 6
Totale 77.636
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Nome #
Gli inibitori della poli (ADP-ribosio) polimerasi (PARP) per superare la chemioresistenza a metilanti e inibitori di topoisomerasi I 1.070
Parte V- Farmaci per il trattamento di infezioni, tumori e malattie immunologiche; Capitoli: 49, Principi di chemioterapia antimicrobica; 50, Farmaci antibatterici; 51, Farmaci antivirali; 52, Farmaci antifungini; 53, Farmaci antiprotozoari; 54, Farmaci anti-elmintici; 55, Farmaci antitumorali. Farmacologia, VII edizione Italiana di Rang and Dale's Pharmacology (VII ed. Inglese); p.616-680. 627
Valproic acid increases the stimulatory effect of estrogens on proliferation of human endometrial adenocarcinoma cells 468
Targeted therapy for brain tumours: role of PARP inhibitors 460
Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells 454
A novel method for monitoring response to chemotherapy based on the detection of circulating cancer cells: a case report 453
Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells 442
Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1 442
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G2/M cell accumulation induced by temozolomide in malignant glioma cells 436
Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence 436
Bacillus Calmette-Guerin down-regulates CD1b induction by granulocyte-macrophage colony stimulating factor in human peripheral blood monocytes 434
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide 432
INVECCHIAMENTO, IMMUNITÀ E FARMACI 432
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity 430
Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk? 429
VIII edizione Rang & Dale's Pharmacology, edizione italiana Rang & Dale Farmacologia Edra LSWR Edizioni 9788821440397. 429
BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression 425
BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib. 425
Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells 423
The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma 421
Temozolomide: An Update on Pharmacological Strategies to Increase its Antitumour Activity 420
Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site 419
Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells 419
Exogenous Control of the Expression of Group I CD1 Molecules Competent for Presentation of Microbial Nonpeptide Antigens to Human T Lymphocytes 419
Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes 415
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 414
Challenging resistance mechanisms to therapies for metastatic melanoma 413
Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds 412
Cisplatin increases sensitivity of human leukemic blasts to triazene compounds 411
Cilengitide down-modulates invasiveness and vasculogenic mimicry of neuropilin-1 expressing melanoma cells through the inhibition of αvβ5 integrin. 411
Clinical perspectives of PARP inhibitors 410
Exploiting Microglial Functions for the Treatment of Glioblastoma 410
Adjuvant treatment of breast cancer: a pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha 409
Oral administration of PARP inhibitor GPI 18180 increases the anti-tumor activity of temozolomide against intracranial melanoma in mice. 408
Decline of natural cytotoxicity of human lymphocytes following infection with human T-cell leukemia/lymphoma virus (HTLV) 408
Immunopharmacology of antitumor agents. 408
In vitro infection of CD4+ T lymphocytes with HTLV-I generates immortalized cell lines coexpressing lymphoid and myeloid cell markers 407
Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro 407
Ellagic acid inhibits bladder cancer invasiveness and in vivo tumor growth 407
Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes 406
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine 406
Staurosporine increases carcinoembryonic antigen expression in a human colon cancer cell line 404
Detection of circulating tumor cells is improved by drug-induced antigen up-regulation: preclinical and clinical studies 404
null 404
Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells 403
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: Influence of 3'-azido-3'-deoxythymidine 403
Mutation of the mismatch repair gene hMSH2 and hMSH6 in a human T-cell leukemia line tolerant to methylating agents 402
Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors. 401
Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components 401
Influence of bacillus calmette-guerin (BCG) on induction of antigen-presenting cd1b molecule by granulocyte- macrophage colony stimulating factor (GM-CSF). 401
A novel water-soluble nitrobenzoxadiazole is highly effective against vemurafenib-resistant human melanoma cells 401
Trattato di Medicina Interna Gasbarrini G. Volume 3 400
Triazene compounds induce apoptosis in O6-alkylguanine-DNA alkyltransferase deficient leukemia cell lines 399
Pharmacological strategies to increase the antitumor activity of methylating agents 399
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro 398
Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin 396
Effect of hydrocortisone on human natural killer activity and its modulation by beta interferon 395
Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors 394
Parte V- Farmaci per il trattamento di infezioni, tumori e malattie immunologiche (capitoli 49, 50, 51, 52, 53, 54, 55) Farmacologia VII edizione Italiana di Rang and Dale's Pharmacology (VII ed. Inglese). p. 616-680. 394
5(2-bromovinyl)-2’-deoxyuridine (BVDU), increases the amount of chromatid breaks induced by bleomycin in mismatch repair deficient tumor cells by inhibiting homologous recombination 393
Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells 392
Valproic acid inhibits proliferation and affects androgen sensitività in prostatic cancer cells 391
Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome 389
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (ADP-ribose) polymerase inhibitor 387
Novel Glutathione S-Transferase Inhibitor Enhances Temozolomide Efficacy Against Malignant Melanoma 52nd Annual Meeting of the Italian Cancer Society. Lost in translation: bridging the gap between cancer research and effective therapies 387
Antigenic changes induced in tumor cells in vivo by dimethil-imidazole carboxamide (DTIC) 387
Telomerase as a potential anticancer target: growth inhibition and genomic instability 386
I FARMACI E LA FRAGILITA’ 386
Pharmacological modulation of carcinoembryonic antigen in human cancer cells: studies with staurosporine 384
Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis 384
Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells 383
Inhibition of O-6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic coils to apoptosis induced by temozolomide 382
Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I) 382
Primary cultures of microglial cells for testing toxicity of anticancer drugs. 382
Poly (ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis 382
Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen 381
In vitro infection of leukemic bone marrow with HTLV-I generates immortalized cell lines expressing T or myeloid cell phenotype 380
PARP-1 inhibition to treat cancer, ischemia, inflammation 380
Role of PARP, NF-kB and telomerase in necrosis induced by selective methylation of N3-adenine. 380
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr 380
Monoclonal antibodies to CTLA-4 with focus on ipilimumab 379
Role of DNA repair pathways in the control of common fragile sites expression. 378
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro 377
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells 376
Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers. 376
Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan. 375
5-Fluorouracil increases carcinoembryonic antigen expression and shedding in colon cancer cell clones with different basal levels of the molecule 374
Neuropilin-1 as Therapeutic Target for Malignant Melanoma. 374
Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells 373
NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug. 373
Modulation of GDF11 expression and synaptic plasticity by age and training 373
Ipilimumab: A novel immunostimulatory monoclonal antibody for the treatment of cancer 372
Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanoma 372
High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro 372
Chimeric molecules between keratinocyte growth factor and basic fibroblast growth factor define domains that confer receptor binding specificities 371
Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype. 369
DNA damaging agents can induce celll cycle arrest in different phases of mitosis 369
VEGFR-1 derived peptide specifically inhibits PlGF and VEGF-B-induced migration of endothelial cells and in vivo angiogenesis. 369
In vitro combined effects of human interferons and interleukin-2 on natural cell-mediated cytotoxicity 367
PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy 367
Totale 40.940
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Categoria #
all - tutte 146.381
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 146.381
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202020.183 0 1.860 1.524 2.107 1.993 2.345 1.900 1.969 1.934 1.700 1.394 1.457
2020/202112.994 1.498 1.489 1.320 1.609 1.375 1.501 1.603 1.263 332 281 538 185
2021/20222.502 97 322 177 131 67 201 143 135 204 174 120 731
2022/20233.228 331 188 77 401 262 759 272 213 296 48 270 111
2023/20241.835 173 41 94 90 147 593 146 77 61 55 104 254
2024/2025292 235 57 0 0 0 0 0 0 0 0 0 0
Totale 85.402