IRIS
GRAZIANI, GRAZIA
 Distribuzione geografica
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Continente #
NA - Nord America 81.206
EU - Europa 9.550
AS - Asia 9.422
SA - Sud America 1.127
AF - Africa 118
OC - Oceania 36
Continente sconosciuto - Info sul continente non disponibili 14
Totale 101.473
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Nazione #
US - Stati Uniti d'America 80.962
SG - Singapore 5.065
IT - Italia 2.517
CN - Cina 1.877
DE - Germania 1.225
UA - Ucraina 1.163
RU - Federazione Russa 1.008
BR - Brasile 940
FR - Francia 772
IE - Irlanda 748
HK - Hong Kong 682
VN - Vietnam 581
FI - Finlandia 452
SE - Svezia 439
GB - Regno Unito 433
PL - Polonia 359
KR - Corea 307
JP - Giappone 298
NL - Olanda 150
CA - Canada 123
IN - India 123
MX - Messico 79
ID - Indonesia 75
AR - Argentina 73
BD - Bangladesh 59
AT - Austria 50
TR - Turchia 47
ES - Italia 44
ZA - Sudafrica 44
IQ - Iraq 41
CZ - Repubblica Ceca 39
PH - Filippine 33
CO - Colombia 31
AU - Australia 30
IR - Iran 29
BE - Belgio 27
PK - Pakistan 26
AL - Albania 25
VE - Venezuela 23
EC - Ecuador 21
MA - Marocco 19
LT - Lituania 18
UZ - Uzbekistan 18
IL - Israele 17
EG - Egitto 16
KG - Kirghizistan 16
CL - Cile 14
CH - Svizzera 13
SA - Arabia Saudita 13
AE - Emirati Arabi Uniti 12
EU - Europa 12
KE - Kenya 12
PE - Perù 12
BG - Bulgaria 11
MY - Malesia 11
JO - Giordania 10
KZ - Kazakistan 9
TW - Taiwan 9
JM - Giamaica 8
TN - Tunisia 8
BH - Bahrain 7
DK - Danimarca 7
DO - Repubblica Dominicana 7
NP - Nepal 7
PT - Portogallo 7
TH - Thailandia 7
AZ - Azerbaigian 6
PS - Palestinian Territory 6
PY - Paraguay 6
RO - Romania 6
TT - Trinidad e Tobago 6
GE - Georgia 5
GT - Guatemala 5
LB - Libano 5
MK - Macedonia 5
SY - Repubblica araba siriana 5
UY - Uruguay 5
DZ - Algeria 4
HU - Ungheria 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
OM - Oman 4
SI - Slovenia 4
CY - Cipro 3
EE - Estonia 3
GR - Grecia 3
HN - Honduras 3
KH - Cambogia 3
LU - Lussemburgo 3
PA - Panama 3
RS - Serbia 3
BB - Barbados 2
BY - Bielorussia 2
CR - Costa Rica 2
ET - Etiopia 2
HR - Croazia 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
MW - Malawi 2
Totale 101.446
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Città #
Woodbridge 24.329
Wilmington 19.895
Houston 19.892
Singapore 2.109
Ann Arbor 2.050
Fairfield 1.618
Ashburn 1.382
Chandler 1.044
Jacksonville 1.018
San Jose 886
Beijing 698
Dublin 691
Hong Kong 669
Seattle 653
Cambridge 549
Medford 533
New York 519
Rome 458
Dearborn 451
Santa Clara 312
The Dalles 308
Kraków 301
Council Bluffs 259
Dallas 256
Lawrence 255
Tokyo 230
Los Angeles 223
Helsinki 203
Milan 180
Ho Chi Minh City 177
Mülheim 176
Moscow 147
Buffalo 141
Hanoi 131
Menlo Park 127
Lauterbourg 112
Zhengzhou 97
San Diego 91
São Paulo 90
Boardman 84
Nuremberg 61
Guangzhou 59
Phoenix 58
Mountain View 56
Redwood City 54
University Park 53
Atlanta 49
Chicago 49
Jakarta 49
London 48
Falls Church 47
Frankfurt am Main 45
Munich 43
Nanjing 41
Shanghai 41
Hefei 40
Norwalk 40
Palo Alto 40
Naples 38
San Mateo 37
Orem 35
Toronto 35
Columbus 34
Warsaw 34
Redondo Beach 33
Rio de Janeiro 31
Verona 31
Florence 30
Hangzhou 30
San Francisco 30
Xi'an 29
Brooklyn 28
Denver 27
Johannesburg 27
Civitavecchia 26
Brussels 25
Seoul 25
Belo Horizonte 24
Catania 24
Montreal 24
Stockholm 24
Prague 23
Kunming 22
North Bergen 22
Pisa 22
Campinas 20
Engelhard 20
Saint Petersburg 20
Salt Lake City 20
Baghdad 19
Bari 19
Mexico City 19
Ottawa 19
Boston 18
Pune 18
Turin 18
Amsterdam 17
Da Nang 17
Haiphong 17
Lappeenranta 17
Totale 85.265
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Nome #
Gli inibitori della poli (ADP-ribosio) polimerasi (PARP) per superare la chemioresistenza a metilanti e inibitori di topoisomerasi I 1.530
Parte V- Farmaci per il trattamento di infezioni, tumori e malattie immunologiche; Capitoli: 49, Principi di chemioterapia antimicrobica; 50, Farmaci antibatterici; 51, Farmaci antivirali; 52, Farmaci antifungini; 53, Farmaci antiprotozoari; 54, Farmaci anti-elmintici; 55, Farmaci antitumorali. Farmacologia, VII edizione Italiana di Rang and Dale's Pharmacology (VII ed. Inglese); p.616-680. 676
Temozolomide: An Update on Pharmacological Strategies to Increase its Antitumour Activity 648
Influence of bacillus calmette-guerin (BCG) on induction of antigen-presenting cd1b molecule by granulocyte- macrophage colony stimulating factor (GM-CSF). 599
Chimeric molecules between keratinocyte growth factor and basic fibroblast growth factor define domains that confer receptor binding specificities 548
BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib. 545
Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells 535
A novel method for monitoring response to chemotherapy based on the detection of circulating cancer cells: a case report 530
Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1 529
Requirement of phospholipase C-catalyzed hydrolysis of phosphatidylcholine for maturation of Xenopus laevis oocytes in response to insulin and ras p21 527
Differential profile of NK target structures (NKTS) of mouse fibroblasts and lymphoma cells 521
Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk? 517
Cilengitide down-modulates invasiveness and vasculogenic mimicry of neuropilin-1 expressing melanoma cells through the inhibition of αvβ5 integrin. 513
Valproic acid increases the stimulatory effect of estrogens on proliferation of human endometrial adenocarcinoma cells 512
Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells 505
VIII edizione Rang & Dale's Pharmacology, edizione italiana Rang & Dale Farmacologia Edra LSWR Edizioni 9788821440397. 503
BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression 502
Bacillus Calmette-Guerin down-regulates CD1b induction by granulocyte-macrophage colony stimulating factor in human peripheral blood monocytes 500
Targeted therapy for brain tumours: role of PARP inhibitors 494
Adjuvant treatment of breast cancer: a pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha 493
Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells 489
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G2/M cell accumulation induced by temozolomide in malignant glioma cells 488
INVECCHIAMENTO, IMMUNITÀ E FARMACI 485
Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence 482
5(2-bromovinyl)-2’-deoxyuridine (BVDU), increases the amount of chromatid breaks induced by bleomycin in mismatch repair deficient tumor cells by inhibiting homologous recombination 481
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 480
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity 478
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide 477
Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site 476
Ellagic acid inhibits bladder cancer invasiveness and in vivo tumor growth 475
I FARMACI E LA FRAGILITA’ 474
A novel water-soluble nitrobenzoxadiazole is highly effective against vemurafenib-resistant human melanoma cells 472
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro 471
Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes 470
Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors. 469
Cisplatin increases sensitivity of human leukemic blasts to triazene compounds 469
Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome 468
Trattato di Medicina Interna Gasbarrini G. Volume 3 467
Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells 467
Exogenous Control of the Expression of Group I CD1 Molecules Competent for Presentation of Microbial Nonpeptide Antigens to Human T Lymphocytes 466
Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin 465
Decline of natural cytotoxicity of human lymphocytes following infection with human T-cell leukemia/lymphoma virus (HTLV) 465
Challenging resistance mechanisms to therapies for metastatic melanoma 464
Immunopharmacology of antitumor agents. 463
Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components 458
Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells 458
The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma 458
Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds 457
Detection of circulating tumor cells is improved by drug-induced antigen up-regulation: preclinical and clinical studies 457
Mutation of the mismatch repair gene hMSH2 and hMSH6 in a human T-cell leukemia line tolerant to methylating agents 454
Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes 453
Pharmacological strategies to increase the antitumor activity of methylating agents 453
Oral administration of PARP inhibitor GPI 18180 increases the anti-tumor activity of temozolomide against intracranial melanoma in mice. 453
Traduzione e revisione capitoli di 38, 39, 40, 43, 48 e 56 della 10a edizione 2007 Inglese Basic and Clinical Pharmacology McGraw-Hill - Katzung corrispondente alla 7a edizione 2009 Italiana Piccin 453
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine 453
Exploiting Microglial Functions for the Treatment of Glioblastoma 453
Novel Glutathione S-Transferase Inhibitor Enhances Temozolomide Efficacy Against Malignant Melanoma 52nd Annual Meeting of the Italian Cancer Society. Lost in translation: bridging the gap between cancer research and effective therapies 451
Clinical perspectives of PARP inhibitors 450
Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C 450
New aspects of immune responses against mycobacteria: immunopharmacology studies 450
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: Influence of 3'-azido-3'-deoxythymidine 450
In vitro infection of leukemic bone marrow with HTLV-I generates immortalized cell lines expressing T or myeloid cell phenotype 449
Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells 449
In vitro infection of CD4+ T lymphocytes with HTLV-I generates immortalized cell lines coexpressing lymphoid and myeloid cell markers 448
Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro 447
Pharmacological modulation of carcinoembryonic antigen in human cancer cells: studies with staurosporine 445
The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma 442
Staurosporine increases carcinoembryonic antigen expression in a human colon cancer cell line 440
Modulation of GDF11 expression and synaptic plasticity by age and training 440
Antigenic changes induced in tumor cells in vivo by dimethil-imidazole carboxamide (DTIC) 438
Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I) 437
Role of PARP, NF-kB and telomerase in necrosis induced by selective methylation of N3-adenine. 437
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr 437
Triazene compounds induce apoptosis in O6-alkylguanine-DNA alkyltransferase deficient leukemia cell lines 436
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro 436
Parte V- Farmaci per il trattamento di infezioni, tumori e malattie immunologiche (capitoli 49, 50, 51, 52, 53, 54, 55) Farmacologia VII edizione Italiana di Rang and Dale's Pharmacology (VII ed. Inglese). p. 616-680. 436
Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding 434
Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells 433
Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors 433
Monoclonal antibodies to CTLA-4 with focus on ipilimumab 433
Role of DNA repair pathways in the control of common fragile sites expression. 432
5-Fluorouracil increases carcinoembryonic antigen expression and shedding in colon cancer cell clones with different basal levels of the molecule 432
Apoptotic and clastogenic effects of methylating agents, alone or combined with poly(ADP-ribose) polymerase inhibitor, in peripheral blood lymphocytes 431
Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers. 431
Capitoli 37, 38, 39, 55 di Farmacologia IX Ed. Italiana di Katzung B.G. Masters S.B. Trevor A.J. (XII Ed. Americana) 431
Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide. 430
Inhibition of O-6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic coils to apoptosis induced by temozolomide 429
Activity against melanoma of an anti-vascular endothelial growth factor receptor-1 (VEGFR-1) monoclonal antibody that does not hamper ligand binding 429
PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy 428
Valproic acid inhibits proliferation and affects androgen sensitività in prostatic cancer cells 428
Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells 428
Poly (ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis 428
Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen 427
Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells 427
DNA damaging agents can induce celll cycle arrest in different phases of mitosis 427
NF-kB is activated in response to temozolomide and confers protection against drug-induced cell growth inhibition 427
Neuropilin-1 as Therapeutic Target for Malignant Melanoma. 427
High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro 427
Effect of hydrocortisone on human natural killer activity and its modulation by beta interferon 425
Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanoma 425
Totale 47.718
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Categoria #
all - tutte 209.412
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 209.412
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021723 0 0 0 0 0 0 0 0 0 0 538 185
2021/20222.502 97 322 177 131 67 201 143 135 204 174 120 731
2022/20233.220 331 188 77 401 262 759 271 206 296 48 270 111
2023/20241.826 168 41 94 90 146 590 146 77 61 55 104 254
2024/20257.332 235 1.362 659 357 244 495 289 394 711 379 1.190 1.017
2025/20269.634 768 465 1.317 707 939 385 1.193 1.516 1.354 983 7 0
Totale 102.059