IRIS
GRAZIANI, GRAZIA
 Distribuzione geografica
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Continente #
NA - Nord America 77.190
EU - Europa 7.498
AS - Asia 2.852
SA - Sud America 47
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 13
AF - Africa 11
Totale 87.627
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Nazione #
US - Stati Uniti d'America 77.124
IT - Italia 2.013
SG - Singapore 1.361
UA - Ucraina 1.146
DE - Germania 1.096
CN - Cina 936
IE - Irlanda 741
FR - Francia 594
RU - Federazione Russa 419
SE - Svezia 416
GB - Regno Unito 319
PL - Polonia 314
KR - Corea 292
FI - Finlandia 242
JP - Giappone 64
NL - Olanda 55
CA - Canada 44
IN - India 44
ID - Indonesia 41
CZ - Repubblica Ceca 34
BE - Belgio 25
IR - Iran 23
BR - Brasile 21
MX - Messico 18
VN - Vietnam 17
HK - Hong Kong 14
PH - Filippine 14
CO - Colombia 13
AT - Austria 12
AU - Australia 12
EU - Europa 12
KG - Kirghizistan 12
AL - Albania 11
IL - Israele 11
ES - Italia 9
BG - Bulgaria 8
CH - Svizzera 8
CL - Cile 7
DK - Danimarca 5
MK - Macedonia 5
RO - Romania 5
TR - Turchia 5
AR - Argentina 4
LT - Lituania 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
TW - Taiwan 4
EG - Egitto 3
HU - Ungheria 3
LU - Lussemburgo 3
MY - Malesia 3
AE - Emirati Arabi Uniti 2
GR - Grecia 2
MA - Marocco 2
MW - Malawi 2
UZ - Uzbekistan 2
A1 - Anonimo 1
BD - Bangladesh 1
CR - Costa Rica 1
CY - Cipro 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EC - Ecuador 1
EE - Estonia 1
GT - Guatemala 1
HR - Croazia 1
IQ - Iraq 1
JM - Giamaica 1
KZ - Kazakistan 1
LK - Sri Lanka 1
MD - Moldavia 1
MU - Mauritius 1
NO - Norvegia 1
PE - Perù 1
PS - Palestinian Territory 1
SA - Arabia Saudita 1
SC - Seychelles 1
SI - Slovenia 1
ZA - Sudafrica 1
Totale 87.627
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Città #
Woodbridge 24.329
Wilmington 19.893
Houston 19.875
Ann Arbor 2.050
Fairfield 1.618
Singapore 1.175
Chandler 1.044
Ashburn 1.024
Jacksonville 1.015
Dublin 688
Seattle 639
Cambridge 549
Medford 533
Dearborn 451
New York 439
Beijing 393
Rome 369
Kraków 301
Lawrence 255
Santa Clara 252
Mülheim 176
Milan 154
Menlo Park 127
Zhengzhou 94
San Diego 90
Moscow 86
Boardman 71
Mountain View 56
Redwood City 54
University Park 53
Falls Church 47
Nanjing 40
Norwalk 40
Palo Alto 40
Guangzhou 38
Hefei 38
Jakarta 37
San Mateo 37
Shanghai 31
Verona 31
London 30
Naples 29
Civitavecchia 26
Hangzhou 26
Phoenix 25
Brussels 24
Los Angeles 22
Helsinki 21
Kunming 21
Prague 21
Engelhard 20
Pisa 20
Saint Petersburg 20
Catania 19
Ottawa 19
Seoul 19
Toronto 19
Nuremberg 18
Florence 17
Munich 17
Council Bluffs 16
Del Norte 16
Bari 15
Nanchang 15
Napoli 15
Pune 15
Turin 15
Dong Ket 14
Fuzhou 14
Jinan 14
Nürnberg 14
Indiana 13
Kansas City 12
Palermo 12
Scisciano 12
Brno 11
Hebei 11
Redmond 11
Chicago 10
Kilburn 10
Padova 10
Washington 10
Bologna 9
Casalnuovo Di Napoli 9
Chengdu 9
Hong Kong 9
Manila 9
Paris 9
Shenyang 9
Center 8
Changsha 8
San Jose 8
Warsaw 8
Auburn Hills 7
Creede 7
Frankfurt am Main 7
Pavia 7
Pioppi 7
Salt Lake City 7
Segrate 7
Totale 79.094
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Nome #
Gli inibitori della poli (ADP-ribosio) polimerasi (PARP) per superare la chemioresistenza a metilanti e inibitori di topoisomerasi I 1.224
Parte V- Farmaci per il trattamento di infezioni, tumori e malattie immunologiche; Capitoli: 49, Principi di chemioterapia antimicrobica; 50, Farmaci antibatterici; 51, Farmaci antivirali; 52, Farmaci antifungini; 53, Farmaci antiprotozoari; 54, Farmaci anti-elmintici; 55, Farmaci antitumorali. Farmacologia, VII edizione Italiana di Rang and Dale's Pharmacology (VII ed. Inglese); p.616-680. 640
Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells 475
Valproic acid increases the stimulatory effect of estrogens on proliferation of human endometrial adenocarcinoma cells 472
A novel method for monitoring response to chemotherapy based on the detection of circulating cancer cells: a case report 468
Targeted therapy for brain tumours: role of PARP inhibitors 468
Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1 457
Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells 455
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity 447
Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk? 447
VIII edizione Rang & Dale's Pharmacology, edizione italiana Rang & Dale Farmacologia Edra LSWR Edizioni 9788821440397. 447
Bacillus Calmette-Guerin down-regulates CD1b induction by granulocyte-macrophage colony stimulating factor in human peripheral blood monocytes 445
INVECCHIAMENTO, IMMUNITÀ E FARMACI 443
Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence 443
BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression 442
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G2/M cell accumulation induced by temozolomide in malignant glioma cells 440
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide 438
BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib. 433
Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells 432
Exogenous Control of the Expression of Group I CD1 Molecules Competent for Presentation of Microbial Nonpeptide Antigens to Human T Lymphocytes 429
Temozolomide: An Update on Pharmacological Strategies to Increase its Antitumour Activity 429
Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site 428
The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma 428
Challenging resistance mechanisms to therapies for metastatic melanoma 426
Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells 424
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine 424
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib 424
Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes 423
Immunopharmacology of antitumor agents. 423
Cilengitide down-modulates invasiveness and vasculogenic mimicry of neuropilin-1 expressing melanoma cells through the inhibition of αvβ5 integrin. 423
I FARMACI E LA FRAGILITA’ 423
Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors. 422
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro 422
Clinical perspectives of PARP inhibitors 421
Exploiting Microglial Functions for the Treatment of Glioblastoma 421
Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro 420
Cisplatin increases sensitivity of human leukemic blasts to triazene compounds 418
Adjuvant treatment of breast cancer: a pilot immunochemotherapy study with CMF, interleukin-2 and interferon alpha 418
Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: Influence of 3'-azido-3'-deoxythymidine 417
Oral administration of PARP inhibitor GPI 18180 increases the anti-tumor activity of temozolomide against intracranial melanoma in mice. 416
Decline of natural cytotoxicity of human lymphocytes following infection with human T-cell leukemia/lymphoma virus (HTLV) 416
Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds 415
Mutation of the mismatch repair gene hMSH2 and hMSH6 in a human T-cell leukemia line tolerant to methylating agents 414
Ellagic acid inhibits bladder cancer invasiveness and in vivo tumor growth 414
Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes 412
Detection of circulating tumor cells is improved by drug-induced antigen up-regulation: preclinical and clinical studies 412
Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells 412
Pharmacological strategies to increase the antitumor activity of methylating agents 411
Staurosporine increases carcinoembryonic antigen expression in a human colon cancer cell line 410
In vitro infection of CD4+ T lymphocytes with HTLV-I generates immortalized cell lines coexpressing lymphoid and myeloid cell markers 410
A novel water-soluble nitrobenzoxadiazole is highly effective against vemurafenib-resistant human melanoma cells 408
Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components 405
Trattato di Medicina Interna Gasbarrini G. Volume 3 405
Influence of bacillus calmette-guerin (BCG) on induction of antigen-presenting cd1b molecule by granulocyte- macrophage colony stimulating factor (GM-CSF). 405
null 404
Triazene compounds induce apoptosis in O6-alkylguanine-DNA alkyltransferase deficient leukemia cell lines 403
5(2-bromovinyl)-2’-deoxyuridine (BVDU), increases the amount of chromatid breaks induced by bleomycin in mismatch repair deficient tumor cells by inhibiting homologous recombination 402
Pharmacological modulation of carcinoembryonic antigen in human cancer cells: studies with staurosporine 402
Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin 400
Effect of hydrocortisone on human natural killer activity and its modulation by beta interferon 399
Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells 399
Parte V- Farmaci per il trattamento di infezioni, tumori e malattie immunologiche (capitoli 49, 50, 51, 52, 53, 54, 55) Farmacologia VII edizione Italiana di Rang and Dale's Pharmacology (VII ed. Inglese). p. 616-680. 399
Valproic acid inhibits proliferation and affects androgen sensitività in prostatic cancer cells 398
Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome 398
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (ADP-ribose) polymerase inhibitor 397
Novel Glutathione S-Transferase Inhibitor Enhances Temozolomide Efficacy Against Malignant Melanoma 52nd Annual Meeting of the Italian Cancer Society. Lost in translation: bridging the gap between cancer research and effective therapies 397
Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors 397
Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers. 396
Telomerase as a potential anticancer target: growth inhibition and genomic instability 393
Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen 392
Inhibition of O-6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic coils to apoptosis induced by temozolomide 392
Antigenic changes induced in tumor cells in vivo by dimethil-imidazole carboxamide (DTIC) 392
Role of PARP, NF-kB and telomerase in necrosis induced by selective methylation of N3-adenine. 391
Primary cultures of microglial cells for testing toxicity of anticancer drugs. 391
Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells 390
Poly (ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis 390
Neuropilin-1 as Therapeutic Target for Malignant Melanoma. 390
Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis 390
In vitro infection of leukemic bone marrow with HTLV-I generates immortalized cell lines expressing T or myeloid cell phenotype 388
Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells 387
DNA damaging agents can induce celll cycle arrest in different phases of mitosis 387
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr 387
Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanoma 387
Role of DNA repair pathways in the control of common fragile sites expression. 386
Ipilimumab: A novel immunostimulatory monoclonal antibody for the treatment of cancer 386
Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I) 385
PARP-1 inhibition to treat cancer, ischemia, inflammation 385
Capitoli 37, 38, 39, 55 di Farmacologia IX Ed. Italiana di Katzung B.G. Masters S.B. Trevor A.J. (XII Ed. Americana) 385
Monoclonal antibodies to CTLA-4 with focus on ipilimumab 384
Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan. 384
Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro 383
5-Fluorouracil increases carcinoembryonic antigen expression and shedding in colon cancer cell clones with different basal levels of the molecule 383
Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide. 383
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells 381
PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy 380
The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma 380
NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug. 380
Modulation of GDF11 expression and synaptic plasticity by age and training 380
Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype. 379
NF-kB is activated in response to temozolomide and confers protection against drug-induced cell growth inhibition 379
Totale 42.085
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Categoria #
all - tutte 162.042
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 162.042
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202012.699 0 0 0 0 0 2.345 1.900 1.969 1.934 1.700 1.394 1.457
2020/202112.994 1.498 1.489 1.320 1.609 1.375 1.501 1.603 1.263 332 281 538 185
2021/20222.502 97 322 177 131 67 201 143 135 204 174 120 731
2022/20233.220 331 188 77 401 262 759 271 206 296 48 270 111
2023/20241.826 168 41 94 90 146 590 146 77 61 55 104 254
2024/20253.068 235 1.362 659 357 244 211 0 0 0 0 0 0
Totale 88.161