| Nome |
# |
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Strategies to improve ellagic acid bioavailability: from natural or semisynthetic derivatives to nanotechnological approaches based on innovative carriers, file e291c0d8-f563-cddb-e053-3a05fe0aa144
|
1.450
|
|
Monoclonal antibodies to CTLA-4 with focus on ipilimumab, file e291c0d4-c1bc-cddb-e053-3a05fe0aa144
|
663
|
|
BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib., file e291c0d4-c485-cddb-e053-3a05fe0aa144
|
476
|
|
Common fragile sites in colon cancer cell lines: role of mismatch repair, RAD51 and poly(ADP-ribose) polymerase-1, file e291c0d4-aaae-cddb-e053-3a05fe0aa144
|
375
|
|
Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression, file e291c0d4-b971-cddb-e053-3a05fe0aa144
|
372
|
|
Ellagic acid inhibits bladder cancer invasiveness and in vivo tumor growth, file e291c0d6-3e98-cddb-e053-3a05fe0aa144
|
340
|
|
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges, file e291c0d8-ae48-cddb-e053-3a05fe0aa144
|
322
|
|
Cilengitide down-modulates invasiveness and vasculogenic mimicry of neuropilin-1 expressing melanoma cells through the inhibition of αvβ5 integrin., file e291c0d4-a3f6-cddb-e053-3a05fe0aa144
|
281
|
|
Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness., file e291c0d4-89e2-cddb-e053-3a05fe0aa144
|
242
|
|
null, file e291c0d7-d353-cddb-e053-3a05fe0aa144
|
219
|
|
High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro, file e291c0d6-a978-cddb-e053-3a05fe0aa144
|
216
|
|
Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding, file e291c0d6-3dd7-cddb-e053-3a05fe0aa144
|
208
|
|
Neuropilin-1 as Therapeutic Target for Malignant Melanoma., file e291c0d5-d44f-cddb-e053-3a05fe0aa144
|
198
|
|
PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets., file e291c0d4-89e4-cddb-e053-3a05fe0aa144
|
181
|
|
Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition, file e291c0d4-b8f3-cddb-e053-3a05fe0aa144
|
179
|
|
Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers., file e291c0d4-9d8c-cddb-e053-3a05fe0aa144
|
168
|
|
The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells, file e291c0d6-d24c-cddb-e053-3a05fe0aa144
|
168
|
|
NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug., file e291c0d4-c072-cddb-e053-3a05fe0aa144
|
166
|
|
PARP-1 modulates amyloid beta peptide-induced neuronal damage., file e291c0d4-b7c1-cddb-e053-3a05fe0aa144
|
162
|
|
null, file e291c0d4-b78a-cddb-e053-3a05fe0aa144
|
161
|
|
null, file e291c0d6-db10-cddb-e053-3a05fe0aa144
|
159
|
|
Role of VEGFs/VEGFR-1 signaling and its inhibition in modulating tumor invasion: experimental evidence in different metastatic cancer models, file e291c0d8-2ff7-cddb-e053-3a05fe0aa144
|
143
|
|
Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome, file e291c0d6-3711-cddb-e053-3a05fe0aa144
|
131
|
|
Role of PARP Inhibitors in Cancer Immunotherapy: Potential Friends to Immune Activating Molecules and Foes to Immune Checkpoints, file c42aad10-16f2-4f82-9a6c-2dd35710d09a
|
118
|
|
Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB, file e291c0d4-b7be-cddb-e053-3a05fe0aa144
|
115
|
|
Targeting tumor-associated macrophages to increase the efficacy of immune checkpoint inhibitors: a glimpse into novel therapeutic approaches for metastatic melanoma, file e291c0d8-9f71-cddb-e053-3a05fe0aa144
|
111
|
|
Role of VEGFR-1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib, file e291c0d7-de4f-cddb-e053-3a05fe0aa144
|
106
|
|
Cytotoxicity and differentiating effect of the poly(ADP-ribose) polymerase inhibitor olaparib in myelodysplastic syndromes, file e291c0d7-b022-cddb-e053-3a05fe0aa144
|
104
|
|
Experimental evidence of the antitumor, antimetastatic and antiangiogenic activity of ellagic acid, file e291c0d7-e71b-cddb-e053-3a05fe0aa144
|
93
|
|
EGFR heterogeneity and implications for therapeutic intervention in glioblastoma., file e291c0d7-e720-cddb-e053-3a05fe0aa144
|
85
|
|
Approaching coronavirus disease 2019: Mechanisms of action of repurposed drugs with potential activity against SARS-CoV-2, file e291c0d8-fb30-cddb-e053-3a05fe0aa144
|
83
|
|
Role of BRCA mutations in cancer treatment with poly(ADP-ribose) polymerase (PARP) inhibitors, file e291c0d8-0757-cddb-e053-3a05fe0aa144
|
80
|
|
Saffron and its major ingredients’ effect on colon cancer cells with mismatch repair deficiency and microsatellite instability, file e291c0d9-8e1b-cddb-e053-3a05fe0aa144
|
60
|
|
PDIA3 Expression in Glioblastoma Modulates Macrophage/Microglia Pro-Tumor Activation, file e291c0d8-fa12-cddb-e053-3a05fe0aa144
|
58
|
|
At the cutting edge against cancer: A perspective on immunoproteasome and immune checkpoints modulation as a potential therapeutic intervention, file e291c0d9-98da-cddb-e053-3a05fe0aa144
|
56
|
|
The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation., file e291c0d9-ef2f-cddb-e053-3a05fe0aa144
|
56
|
|
High-Dose Vitamin C: Preclinical Evidence for Tailoring Treatment in Cancer Patients, file e291c0d9-286d-cddb-e053-3a05fe0aa144
|
50
|
|
hTERT Transduction Extends the Lifespan of Primary Pediatric Low-Grade Glioma Cells While Preserving the Biological Response to NGF, file e291c0d9-3834-cddb-e053-3a05fe0aa144
|
48
|
|
VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody, file e291c0d9-d81e-cddb-e053-3a05fe0aa144
|
37
|
|
Editorial, file e291c0d8-bbbc-cddb-e053-3a05fe0aa144
|
33
|
|
Ipilimumab: A novel immunostimulatory monoclonal antibody for the treatment of cancer, file e291c0d4-b7bc-cddb-e053-3a05fe0aa144
|
29
|
|
Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB, file e291c0d4-b7bf-cddb-e053-3a05fe0aa144
|
29
|
|
Insulin-degrading enzyme Is a non proteasomal target of carfilzomib and affects the 20S proteasome inhibition by the drug, file e291c0d9-bff8-cddb-e053-3a05fe0aa144
|
24
|
|
Targeting of PDGF-C/NRP-1 autocrine loop as a new strategy for counteracting the invasiveness of melanoma resistant to braf inhibitors, file 524c0056-1d4a-47d9-81d7-ddec6d82eff5
|
20
|
|
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects, file 24b7954c-ef5f-493e-aaee-5f8ca6b7bf90
|
16
|
|
Targeted therapy for brain tumours: role of PARP inhibitors, file e291c0d4-b7c3-cddb-e053-3a05fe0aa144
|
13
|
|
Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells, file e291c0d4-b803-cddb-e053-3a05fe0aa144
|
12
|
|
Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome, file e291c0d6-3712-cddb-e053-3a05fe0aa144
|
12
|
|
Modulation of GDF11 expression and synaptic plasticity by age and training, file e291c0d8-6a3b-cddb-e053-3a05fe0aa144
|
11
|
|
PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment, file 3caea4ab-29ad-43b3-8223-d277c0f3ee28
|
8
|
|
The Anti-Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) D16F7 Monoclonal Antibody Inhibits Melanoma Adhesion to Soluble VEGFR-1 and Tissue Invasion in Response to Placenta Growth Factor, file defeef27-9957-48d2-ad15-587347f2fb40
|
8
|
|
Challenging resistance mechanisms to therapies for metastatic melanoma, file e291c0d4-88b2-cddb-e053-3a05fe0aa144
|
8
|
|
A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib, file e291c0d4-cc47-cddb-e053-3a05fe0aa144
|
6
|
|
Effects of Glutathione Transferase-Targeting Nitrobenzoxadiazole Compounds in Relation to PD-L1 Status in Human Melanoma Cells, file e291c0d8-0326-cddb-e053-3a05fe0aa144
|
6
|
|
Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?, file e291c0d8-5a7c-cddb-e053-3a05fe0aa144
|
6
|
|
Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers., file e291c0d9-85ab-cddb-e053-3a05fe0aa144
|
6
|
|
Exogenous Control of the Expression of Group I CD1 Molecules Competent for Presentation of Microbial Nonpeptide Antigens to Human T Lymphocytes, file e291c0d4-b787-cddb-e053-3a05fe0aa144
|
5
|
|
The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma, file e291c0d4-b807-cddb-e053-3a05fe0aa144
|
5
|
|
The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design, file 353e83ce-008d-4729-a79c-293c7c8186b5
|
2
|
|
Exploiting Microglial Functions for the Treatment of Glioblastoma, file e291c0d6-2f9d-cddb-e053-3a05fe0aa144
|
2
|
|
Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment, file e291c0d6-b15c-cddb-e053-3a05fe0aa144
|
2
|
|
The Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody D16F7 Inhibits Glioma Growth and Angiogenesis In Vivo., file e291c0d6-d5ff-cddb-e053-3a05fe0aa144
|
2
|
|
Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence, file e291c0d7-d16b-cddb-e053-3a05fe0aa144
|
2
|
|
Physical Exercise and the Hallmarks of Breast Cancer: A Narrative Review, file 544caa1e-4fc1-4a3f-989a-f288bb5744e7
|
1
|
|
Targeting immunoproteasome in neurodegeneration: a glance to the future, file c6d90465-d5ef-4489-bbd4-ba4d3538857b
|
1
|
|
Detection of circulating tumor cells is improved by drug-induced antigen up-regulation: preclinical and clinical studies, file e291c0d3-d561-cddb-e053-3a05fe0aa144
|
1
|
|
Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide., file e291c0d4-82c7-cddb-e053-3a05fe0aa144
|
1
|
|
GITRL (Glucocorticoid-Induced TNF receptor family-Related Ligand) triggering up-regulates VCAM-1 and ICAM-1 and promotes leukocyte adhesion., file e291c0d5-324e-cddb-e053-3a05fe0aa144
|
1
|
|
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation, file e291c0d6-3243-cddb-e053-3a05fe0aa144
|
1
|
|
On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment, file e291c0d7-e397-cddb-e053-3a05fe0aa144
|
1
|
|
Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors, file e291c0d7-e725-cddb-e053-3a05fe0aa144
|
1
|
|
Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders, file e291c0d8-1199-cddb-e053-3a05fe0aa144
|
1
|
|
Vascular endothelial growth factor receptor 1 in glioblastoma-associated microglia/macrophages, file e291c0d8-3148-cddb-e053-3a05fe0aa144
|
1
|
|
DNA inhibitors for the treatment of brain tumors, file e291c0d8-593a-cddb-e053-3a05fe0aa144
|
1
|
|
Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against cutaneous melanoma, file e291c0d8-d721-cddb-e053-3a05fe0aa144
|
1
|
|
Poly(ADP-Ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocytic leukemia: synergistic in vitro antitumor effects with hypomethylating agents or high-dose vitamin C, file e291c0d9-189f-cddb-e053-3a05fe0aa144
|
1
|
|
Impact of Physical Exercise on Melanoma Hallmarks: Current Status of Preclinical and Clinical Research, file e2d4aea6-e078-4f03-878e-cb7a661107f3
|
1
|
| Totale |
8.521 |