IRIS
COSTANZO, ANTONIO
 Distribuzione geografica
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Continente #
NA - Nord America 20.809
AS - Asia 3.327
EU - Europa 3.143
SA - Sud America 426
Continente sconosciuto - Info sul continente non disponibili 246
AF - Africa 61
OC - Oceania 14
Totale 28.026
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Nazione #
US - Stati Uniti d'America 20.656
SG - Singapore 1.415
CN - Cina 837
DE - Germania 457
UA - Ucraina 429
RU - Federazione Russa 425
IT - Italia 372
BR - Brasile 345
HK - Hong Kong 305
SE - Svezia 289
VN - Vietnam 273
IE - Irlanda 261
GB - Regno Unito 228
FR - Francia 223
PL - Polonia 196
FI - Finlandia 125
BD - Bangladesh 104
JP - Giappone 94
KR - Corea 83
CA - Canada 80
IN - India 43
NL - Olanda 29
AR - Argentina 28
BE - Belgio 26
TR - Turchia 21
MX - Messico 20
ZA - Sudafrica 19
ES - Italia 18
CO - Colombia 14
ID - Indonesia 14
IQ - Iraq 14
PK - Pakistan 13
AT - Austria 12
CL - Cile 12
EC - Ecuador 12
IL - Israele 12
KG - Kirghizistan 12
MY - Malesia 12
AU - Australia 11
JM - Giamaica 11
UZ - Uzbekistan 11
PH - Filippine 10
TH - Thailandia 10
EG - Egitto 9
TN - Tunisia 9
EU - Europa 8
RO - Romania 8
CH - Svizzera 7
KZ - Kazakistan 7
CR - Costa Rica 6
HN - Honduras 6
PY - Paraguay 6
SA - Arabia Saudita 6
DK - Danimarca 5
DO - Repubblica Dominicana 5
MA - Marocco 5
NI - Nicaragua 5
NP - Nepal 5
VE - Venezuela 5
DZ - Algeria 4
KE - Kenya 4
LT - Lituania 4
OM - Oman 4
RS - Serbia 4
TT - Trinidad e Tobago 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
BS - Bahamas 3
CY - Cipro 3
ET - Etiopia 3
GR - Grecia 3
GT - Guatemala 3
IR - Iran 3
PT - Portogallo 3
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
CZ - Repubblica Ceca 2
GA - Gabon 2
GH - Ghana 2
HR - Croazia 2
JO - Giordania 2
MD - Moldavia 2
NG - Nigeria 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PE - Perù 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
VC - Saint Vincent e Grenadine 2
A1 - Anonimo 1
A2 - ???statistics.table.value.countryCode.A2??? 1
AD - Andorra 1
AM - Armenia 1
BG - Bulgaria 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BZ - Belize 1
Totale 27.777
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Città #
Woodbridge 4.820
Wilmington 3.887
Houston 3.428
Ann Arbor 895
Singapore 829
Fairfield 801
Ashburn 759
Chandler 635
San Jose 516
Seattle 397
Jacksonville 396
Beijing 320
Hong Kong 297
Cambridge 290
Dublin 259
Medford 222
New York 185
Dearborn 178
Kraków 170
Council Bluffs 141
Santa Clara 137
The Dalles 137
Dallas 111
Los Angeles 105
Lawrence 102
Zhengzhou 84
Tokyo 76
Ho Chi Minh City 71
Hanoi 68
Mülheim 67
Moscow 62
Buffalo 61
Milan 58
Boardman 54
Munich 54
San Diego 49
Rome 48
São Paulo 48
Menlo Park 43
Chicago 37
Denver 35
Helsinki 35
Lauterbourg 34
San Mateo 34
Shanghai 32
Falls Church 31
Atlanta 25
Brussels 24
London 24
Phoenix 23
Brooklyn 22
Montreal 21
Nuremberg 21
Redwood City 21
Turin 19
Hefei 18
Orem 18
Saint Petersburg 17
Toronto 17
Columbus 16
Mountain View 16
Nanjing 16
Manchester 15
University Park 15
Warsaw 15
Frankfurt am Main 14
Stockholm 13
Amsterdam 12
Ankara 12
Chongqing 12
Da Nang 12
Guangzhou 11
Hangzhou 11
Kunming 11
Norwalk 11
Auburn Hills 10
Chennai 10
Jinan 10
Johannesburg 10
Perugia 10
Pune 10
Redondo Beach 10
San Francisco 10
Suzhou 10
Belo Horizonte 9
Boston 9
Miami 9
Poplar 9
Queens 9
Alexandria 8
Changsha 8
Detroit 8
Elk Grove Village 8
Haiphong 8
Kuala Lumpur 8
Naples 8
Nürnberg 8
Verona 8
Washington 8
Wuhan 8
Totale 21.803
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Nome #
The p53/p63/p73 family of transcription factors: overlapping and distinct functions 556
Adalimumab for the treatment of severe psoriasis and psoriatic arthritis 554
Functionalized gold nanoparticles for topical delivery of methotrexate for the possible treatment of psoriasis 539
Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis 518
Superficial and nodular basal cell carcinomas treated with an immune response modifier: a report of seven patients 506
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage 506
IL-21 Promotes Skin Recruitment of CD4+ Cells and Drives IFN- -Dependent Epidermal Hyperplasia 504
Adalimumab for severe psoriasis and psoriatic arthritis: an open-label study in 30 patients previously treated with other biologics 490
Induction of gene expression via activator protein-1 in the ascorbate protection against UV-induced damage 485
Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: Implications for the cellular response to DNA damage 482
Actinic keratosis treated with an immune response modifier: a case report of six patients 471
Increased levels of IL-17 in tear fluid of moderate-to-severe psoriatic patients is reduced by adalimumab therapy 467
MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis 465
IL-21 in the pathogenesis and treatment of skin diseases 456
Topical treatment of basal cell carcinoma with tazarotene: a clinicopathological study on a large series of cases 454
Efficacy of short-term cyclosporine treatment to control psoriasis-related events during efalizumab therapy 451
Psoriasis, from pathogenesis to therapeutic strategies: IL-21 as a novel potential therapeutic target 450
Psoriatic arthritis and CARD15 gene polymorphisms: no evidence for association in the Italian population 446
Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain 443
Structure, function and regulation of p63 and p73 438
PSORS2 markers are not associated with psoriatic arthritis in the Italian population 438
Systemic therapy of primary cutaneous B-cell lymphoma, marginal zone type, with rituximab, a chimeric anti-CD20 monoclonal antibody 436
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage 430
Herpes simplex virus disrupts NF-kappa B regulation by blocking its recruitment on the I kappa B alpha promoter and directing the factor on viral genes. 426
Induction of neuronal differentiation by p73 in a neuroblastoma cell line 420
The tumor suppressor activity of IKK alpha in stratified epithelia is exerted in part via the TGF-beta anti proliferative pathway 420
Elementi di dermatologia 420
Pathogenic role of interleukin-21 in psoriasis 409
What happened after the clinical trials: Long-term safety and efficacy of ustekinumab in daily clinical practice 407
Zosteriform metastasis of occult bronchogenic carcinoma 392
Evidence of increased apoptosis and reduced proliferation in basal cell carcinomas treated with tazarotene 387
Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants  and  386
Efficacy and safety of long-term infliximab therapy in moderate to severe psoriasis and psoriatic arthritis 385
Anti-LL37 antibodies are present in psoriatic arthritis (PsA) patients: New biomarkers in PsA 385
Two new p73 splice variants, gamma and delta, with different transcriptional activity 381
IL-21, a new player in pathogenesis of psoriasis 367
Use of biological drugs in patients with psoriasis and psoriatic arthritis in Italy: Results from the PSONG survey 367
Zosteriform metastasis of occult bronchogenic carcinoma 366
Psoriasis: from pathogenesis to novel therapeutic approaches 362
Effects of topical methotrexate loaded gold nanoparticle in cutaneous inflammatory mouse model 358
High-dose Intravenous Immunoglobulin for Severe Drug Reactions: Efficacy in Toxic Epidermal Necrolysis 356
Secukinumab shows high efficacy irrespective of HLA-Cw6 status in patients with moderate to severe plaque-type psoriasis: Results from extension phase of the SUPREME study 261
A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias 231
Claudin-1 is a p63 target gene with a crucial role in epithelial development 227
Treatment of vitiligo with the 308 nm excimer laser 221
The impact of methodological approaches for presenting long-term clinical data on estimates of efficacy in psoriasis illustrated by three-year treatment data on infliximab 217
308 nm monochromatic excimer light in the treatment of psoriasis 212
A feedback regulatory loop between p63 and Dlx3: implications for epidermal differentiation 205
Safety and efficacy study on etanercept in patients with plaque psoriasis 203
Different applications of monochromatic excimer light in skin diseases 202
Cross-talks in the p53 family - Delta Np63 is an anti-apoptotci target for Delta Np73 alpha and p53 gain-of-function mutants 202
Efalizumab 198
Detection of adalimumab and anti-adalimumab levels by ELISA: clinical considerations 193
p63 and p73 transactivate differentiation gene promoters in human keratinocytes 193
Moderate and severe plaque psoriasis: Cost-of-illness study in Italy 190
A role of p73 in mitotic exit 189
Efficacy of efalizumab in psoriasis patients previously treated with tumour necrosis factor blockers 189
Efficacy of monochromatic excimer laser radiation (308 nm) in the treatment of early stage mycosis fungoides 186
p63 induces key target genes required for epidermal morphogenesis 183
Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways 179
Consecutive use of different biological therapies in the treatment of psoriasis [4] 178
Treasure or artifact: a decade of p63 research speaks for itself 177
Long-term treatment of plaque psoriasis with efalizumab: an Italian experience 173
Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects 171
Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias 168
p73 is regulated by phosphorylation at the G2/M transition 167
CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappa B subunits on IL-8 and Bcl-xL gene promotors 167
The p73 gene is an anti-tumoral target of the RAR beta/gamma-selective retinoid tazarotene 166
RelA/NF-kappa B recruitment on the bax gene promoter antagonizes p73-dependent apoptosis in costimulated T cells 164
CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters 163
Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells 162
Pharmacological treatment of androgenetic alopecia.Result of an observational study 162
Safety and efficacy study on etanercept in patients with plaque psoriasis 161
A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes 157
DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes 156
NF-κB, IκB Kinase and Interacting Signal Networks in Squamous Cell Carcinomas 156
The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting 156
Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells 155
Emerging treatments in the management of psoriasis: biological targeting with ustekinumab 154
Differential regulation of E2F1 apoptotic target genes in response to DNA damage 154
deltaEF1 repressor controls selectively p53 family members during differentiation 151
Efficacy and safety of etanercept in psoriasis after switching from other treatments: An observational study 142
Delta Np63 Knockdown Mice: A Mouse Model for AEC Syndrome 140
IL12B (p40) Gene Polymorphisms Contribute to Ustekinumab Response Prediction in Psoriasis 138
Etanercept for the treatment of severe childhood psoriasis [3] 137
HLA-Cw6 allele confers sensitivity to efalizumab treatment in psoriasis 137
Etanercept reverses downregulation of inhibitor of nuclear factor kappa-B kinase subunit alpha (IKKa) in psoriasis 136
Ustekinumab treatment of erythrodermic psoriasis occurring after physical stress: A report of two cases 133
Assessment of HLA Cw6 genotype and correlation to ustekinumab response in a large cohort of patients with moderate-to-severe psoriasis 129
Pharmacogenomics: getting closer to a tailored therapy? 126
DNp73 alpha protects myogenic cells from apoptosis 125
Long-term ustekinumab treatment for refractory type I pityriasis rubra pilaris 120
Label-free and non-invasive discrimination of HaCaT and melanoma cells in a co-culture model by hyperspectral confocal reflectance microscopy 110
Human leucocyte antigen Cw6 predisposes to clinical response to the inlterleukin-12/23 blocker ustekinumab: results of long-term treatment 108
BRodalumab effectiveness in psoriatic patients that experienced anti-IL17 Intra-Class failure: a multicentre, retrospective study (BRIC - Study) IL-PSO (Italian Landscape Psoriasis) 105
Cw6 but not allele LCE3C_LCE3B deletion confers sensitivity to ustekinumab treatment in psoriasis 104
Gender Influence on Bimekizumab Response in Patients with Psoriasis: Results of a Real-World Multicenter Retrospective Study-IL PSO (Italian Landscape PSOriasis) 99
Keratosis punctata palmoplantaris and malignancies: case report 98
Ustekinumab for treatment of plaque psoriasis in a patient with down syndrome 98
HLA-C*06 and response to ustekinumab in Caucasian patients with psoriasis: Outcome and long-term follow-up 93
Totale 27.556
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Categoria #
all - tutte 78.373
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 78.373
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022901 0 0 0 62 29 116 43 59 83 121 59 329
2022/20231.513 166 132 83 245 134 312 83 74 149 6 94 35
2023/2024519 73 18 29 19 42 140 21 68 3 5 6 95
2024/20252.028 114 420 214 156 38 151 161 98 171 148 194 163
2025/20263.936 353 229 516 311 283 129 460 387 461 446 211 150
2026/20271.301 173 195 737 196 0 0 0 0 0 0 0 0
Totale 28.026