Background: Various reports showed the efficacy of Narrow Band UVB (311-313 nm) and excimer laser (308 nm) in the treatment of psoriasis. Objective: To prove the efficacy of light produced by xenon-cloride excimer at 308 nm (Monochromatic Excimer Light, MEL) in the treatment of stable forms of localized plaque psoriasis. Patients and methods: This study was an open trial with 152 patients affected with stable mild to moderate plaque psoriasis (PASI score between 4 and 12) were treated with a weekly session of MEL A total number of 6-16 sessions was performed with a dose increase according to patient phototype and response. Results: 152 patients were enrolled in the study and 149 completed the protocol. Patients were followed up every two weeks, 57 patients for one-year and 92 patients for 6 months. After 4 months there was complete remission in 87 patients, partial remission in 37 and moderate improvement in 25 patients. Conclusions: These preliminary results suggest that MEL can be considered as a valid option for treatment of selected forms of localized plaque psoriasis.

Nistico', S.p., Saraceno, R., Schipani, C., Costanzo, A., Chimenti, S. (2008). 308 nm monochromatic excimer light in the treatment of psoriasis. JOURNAL OF PLASTIC DERMATOLOGY, 4(3), 263-266.

308 nm monochromatic excimer light in the treatment of psoriasis

NISTICO', STEVEN PAUL;SARACENO, ROSITA;COSTANZO, ANTONIO;CHIMENTI, SERGIO
2008

Abstract

Background: Various reports showed the efficacy of Narrow Band UVB (311-313 nm) and excimer laser (308 nm) in the treatment of psoriasis. Objective: To prove the efficacy of light produced by xenon-cloride excimer at 308 nm (Monochromatic Excimer Light, MEL) in the treatment of stable forms of localized plaque psoriasis. Patients and methods: This study was an open trial with 152 patients affected with stable mild to moderate plaque psoriasis (PASI score between 4 and 12) were treated with a weekly session of MEL A total number of 6-16 sessions was performed with a dose increase according to patient phototype and response. Results: 152 patients were enrolled in the study and 149 completed the protocol. Patients were followed up every two weeks, 57 patients for one-year and 92 patients for 6 months. After 4 months there was complete remission in 87 patients, partial remission in 37 and moderate improvement in 25 patients. Conclusions: These preliminary results suggest that MEL can be considered as a valid option for treatment of selected forms of localized plaque psoriasis.
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/35 - Malattie Cutanee e Veneree
English
Con Impact Factor ISI
308 nm; MEL; Psoriasis
Nistico', S.p., Saraceno, R., Schipani, C., Costanzo, A., Chimenti, S. (2008). 308 nm monochromatic excimer light in the treatment of psoriasis. JOURNAL OF PLASTIC DERMATOLOGY, 4(3), 263-266.
Nistico', Sp; Saraceno, R; Schipani, C; Costanzo, A; Chimenti, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/42219
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