IRIS
TESTI, ROBERTO
 Distribuzione geografica
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Continente #
NA - Nord America 18.228
EU - Europa 1.277
AS - Asia 643
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 6
SA - Sud America 6
AF - Africa 1
Totale 20.167
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Nazione #
US - Stati Uniti d'America 18.215
SG - Singapore 309
DE - Germania 260
UA - Ucraina 235
CN - Cina 204
IT - Italia 178
IE - Irlanda 156
RU - Federazione Russa 109
GB - Regno Unito 91
SE - Svezia 71
FI - Finlandia 65
KR - Corea 53
HK - Hong Kong 40
FR - Francia 37
BE - Belgio 25
PL - Polonia 13
CA - Canada 12
CZ - Repubblica Ceca 10
KG - Kirghizistan 10
NL - Olanda 8
EU - Europa 5
JP - Giappone 5
LT - Lituania 5
AU - Australia 4
BR - Brasile 4
BD - Bangladesh 3
ID - Indonesia 3
IL - Israele 3
NO - Norvegia 3
VN - Vietnam 3
AT - Austria 2
CL - Cile 2
GR - Grecia 2
IN - India 2
IR - Iran 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
RO - Romania 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
DK - Danimarca 1
EG - Egitto 1
KZ - Kazakistan 1
MY - Malesia 1
NI - Nicaragua 1
PH - Filippine 1
RS - Serbia 1
SA - Arabia Saudita 1
TH - Thailandia 1
TR - Turchia 1
Totale 20.167
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Città #
Woodbridge 5.305
Wilmington 4.825
Houston 4.305
Fairfield 612
Ann Arbor 558
Chandler 443
Ashburn 283
Singapore 260
Seattle 243
Jacksonville 224
Cambridge 194
Dearborn 145
Dublin 141
Medford 119
Rome 104
New York 102
Beijing 61
Lawrence 56
Santa Clara 50
Mülheim 42
Guangzhou 41
Hong Kong 40
Menlo Park 33
Munich 28
Brussels 25
Moscow 19
Helsinki 18
Milan 18
San Diego 18
Palo Alto 16
Boardman 15
Falls Church 15
Mountain View 15
Hefei 12
Kraków 12
Redwood City 12
San Mateo 10
Brno 9
Kunming 9
London 9
Los Angeles 9
Norwalk 9
Nanjing 8
University Park 8
Nuremberg 7
Shenyang 7
Nanchang 6
Toronto 6
Wuhan 6
Frankfurt am Main 5
Jinan 5
Saint Petersburg 5
Amsterdam 4
Nürnberg 4
Ottawa 4
Verona 4
Council Bluffs 3
Fuzhou 3
Jakarta 3
Redmond 3
San Jose 3
Ypsilanti 3
Auburn Hills 2
Baotou 2
Chiswick 2
Chongqing 2
Clifton 2
Dalian 2
Del Norte 2
Florence 2
Griesstatt 2
Hangzhou 2
Indiana 2
Kilburn 2
La Veta 2
Novokuznetsk 2
Oslo 2
Parma 2
Rogers 2
Seoul 2
Shanghai 2
Simi Valley 2
Tianjin 2
Tokyo 2
Trieste 2
Vienna 2
Zhengzhou 2
Almaty 1
Ancona 1
Anguillara 1
Atlanta 1
Auckland 1
Balsas 1
Bari 1
Bergamo 1
Berlin 1
Bolton 1
Cairo 1
Changsha 1
Chengdu 1
Totale 18.624
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Nome #
E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia 452
Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin 448
A caspaselike activity is triggered by LPS and is required for survival of human dendritic cells 446
GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion 445
Analysis of intracellular distribution and apoptosis involvement of the Ufd1l gene product by over-expression studies 443
5-aminosalicylic acid enhances anchorage-independent colorectal cancer cell death 438
Preventing the ubiquitin-proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia 437
Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells 436
Disialoganglioside GD3 is released by microglia and induces oligodendrocyte apoptosis 434
Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression 432
A pool of extramitochondrial frataxin that promotes cell survival 428
Primary macrophages infected by human immunodeficiency virus trigger CD95-mediated apoptosis of uninfected astrocytes 426
c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization 425
Caspase-dependent cleavage of c-Abl contributes to apoptosis 422
Mitochondrial lipids as apoptosis regulators 417
Calnexin suppresses GD3 synthase-induced apoptosis 416
C. elegans as a model for Friedreich Ataxia 416
Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells 416
Lipid signaling in CD95-mediated apoptosis 412
Frataxin participates to the hypoxia-induced response in tumors 410
TRANSCRIPTIONAL REGULATION OF INTERLEUKIN-2 GENE-EXPRESSION BY CD69-GENERATED SIGNALS 408
A role for p53 in mitochondrial stress response control of longevity in C. elegans. 407
Intracellular mediators of programmed cell death initiated at the cell surface receptor Fas 401
UVB-induced apoptosis of human dendritic cells: contribution by caspase-dependent and caspase-independent pathways 401
Long-lived C. elegans Mitochondrial mutants as a model for human mitochondrial-associated diseases 399
Mitochondria as sensors of sphingolipids 399
Lipid and glycolipid mediators in CD95-induced apoptotic signaling. 397
GD3 in cellular ageing and apoptosis 397
GD3 ganglioside as an intracellular mediator of apoptosis 397
9-O-acetyl GD3 protects tumor cells from apoptosis 396
Differential regulation of apoptotic cell death in senescent human cells 396
Is it cytotoxicity or apoptosis which causes cell death in autoimmunity? 391
p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress 387
Acetylation suppresses the proapoptotic activity of GD3 ganglioside 384
Differential regulation of apoptotic cell death in senescent human cells 380
In vivo maturation of human frataxin 380
Ceramide catabolism critically controls survival of human dendritic cells 369
GD3 ganglioside and apoptosis 368
Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans 368
p21(Waf1/Cip1/Sdi1) mediates shear stress-dependent antiapoptotic function 366
Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans 366
The ganglioside GD3 as the greek goddess Hecate: Several faces turned towards as many directions 351
Src inhibitors modulate frataxin protein levels 345
Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis 344
Lipopolysaccharide induces jun N-terminal kinase activation in macrophages by a novel Cdc42/Rac-independent pathway involving sequential activation of protein kinase C zeta and phosphatidylcholine-dependent phospholipase C 343
ATM Kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells 323
Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model 303
Biophysical characterisation of the recombinant human frataxin precursor 243
Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia 240
Frataxin deficiency in Friedreich’s ataxia is associated with reduced levels of HAX-1, a regulator of cardiomyocyte death and survival 238
Analyzing the effects of a G137V mutation in the FXN gene 190
SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia 187
GIFT-1, a phase IIa clinical trial to test the safety and efficacy of IFNγ administration in FRDA patients 163
An RNA-seq study in Friedreich ataxia patients identified hsa-miR-148a-3p as a putative prognostic biomarker of the disease 58
Safety and efficacy of interferon γ in friedreich's ataxia 48
Hsa-miR223-3p circulating level is upregulated in Friedreich's ataxia and inversely associated with HCLS1 associated protein X-1, HAX-1 44
Sensitivity of Neuroimaging Indicators in Monitoring the Effects of Interferon Gamma Treatment in Friedreich's Ataxia 39
Drug Repositioning in Friedreich Ataxia 33
Interferon Gamma Enhances Cytoprotective Pathways via Nrf2 and MnSOD Induction in Friedreich’s Ataxia Cells 22
Totale 20.270
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Categoria #
all - tutte 39.245
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.245
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.660 0 0 0 0 0 0 518 510 445 442 335 410
2020/20213.227 349 371 346 436 306 330 433 306 85 95 120 50
2021/2022586 15 26 22 24 32 97 16 21 56 67 18 192
2022/2023917 105 100 80 124 72 164 44 52 89 7 60 20
2023/2024303 41 10 10 5 24 116 11 14 3 4 12 53
2024/2025740 102 291 130 72 53 63 29 0 0 0 0 0
Totale 20.270