The disialoganglioside GD3 can mediate biological functions as diverse as proliferation, differentiation, and apoptosis. Since intracellular level of GD3 is crucial for the cell, understanding the mechanisms by which GD3 metabolism is tightly regulated seems of particular importance. GD3 can be enlisted among the most potent natural inducers of mitochondrial damage and apoptosis. However, some cell types resist GD3-mediated mitochondrial damage through complex mechanisms which are beginning to be unveiled. © 2005 IUBMB.
Malisan F., T.R. (2005). The ganglioside GD3 as the greek goddess Hecate: Several faces turned towards as many directions. IUBMB LIFE, 57(7), 477-482.
Tipologia: | Articolo su rivista |
Citazione: | Malisan F., T.R. (2005). The ganglioside GD3 as the greek goddess Hecate: Several faces turned towards as many directions. IUBMB LIFE, 57(7), 477-482. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/04 - Patologia Generale |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1080/15216540500167179 |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | 2005 |
Titolo: | The ganglioside GD3 as the greek goddess Hecate: Several faces turned towards as many directions |
Autori: | |
Autori: | Malisan F., Testi R. |
Appare nelle tipologie: | 01 - Articolo su rivista |