Ceramides play an important role mediating different cell responses such as proliferation, differentiation, growth arrest and apoptosis. They are released upon sphingomyelin hydrolysis which occurs after triggering of a number of cell surface receptors including CD95. Ceramide generation also regulates glycosphingolipid and ganglioside metabolism. In particular, ganglioside GD3 biosynthesis represents an important event for the progression of apoptotic signals generated by CD95 and mediated by ceramide in hematopoietic cells. Copyright (C) 1999 Federation of European Biochemical Societies.
Malisan, F., & Testi, R. (1999). Lipid signaling in CD95-mediated apoptosis. FEBS LETTERS, 452(2009/02/01 00:00:00.000), 100-103.
Tipologia: | Articolo su rivista |
Citazione: | Malisan, F., & Testi, R. (1999). Lipid signaling in CD95-mediated apoptosis. FEBS LETTERS, 452(2009/02/01 00:00:00.000), 100-103. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/04 - Patologia Generale |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0014-5793(99)00543-8 |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | 1999 |
Titolo: | Lipid signaling in CD95-mediated apoptosis |
Autori: | |
Autori: | Malisan, F; Testi, R |
Appare nelle tipologie: | 01 - Articolo su rivista |