IRIS
OTTONE, TIZIANA
 Distribuzione geografica
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Continente #
NA - Nord America 7.469
EU - Europa 1.558
AS - Asia 636
SA - Sud America 8
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 4
AF - Africa 2
Totale 9.682
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Nazione #
US - Stati Uniti d'America 7.462
IT - Italia 721
SG - Singapore 281
KR - Corea 176
PL - Polonia 172
IE - Irlanda 161
CN - Cina 129
FR - Francia 111
DE - Germania 96
RU - Federazione Russa 96
GB - Regno Unito 64
UA - Ucraina 61
SE - Svezia 21
FI - Finlandia 18
IN - India 15
JP - Giappone 8
NL - Olanda 8
CA - Canada 7
HK - Hong Kong 6
CH - Svizzera 5
BE - Belgio 4
ES - Italia 4
EU - Europa 4
MY - Malesia 4
AT - Austria 3
AU - Australia 3
BR - Brasile 3
CO - Colombia 3
CZ - Repubblica Ceca 3
IR - Iran 3
VN - Vietnam 3
BD - Bangladesh 2
GR - Grecia 2
HU - Ungheria 2
LU - Lussemburgo 2
PK - Pakistan 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AR - Argentina 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
ID - Indonesia 1
LA - Repubblica Popolare Democratica del Laos 1
MA - Marocco 1
NZ - Nuova Zelanda 1
PE - Perù 1
RO - Romania 1
SD - Sudan 1
TH - Thailandia 1
TW - Taiwan 1
UZ - Uzbekistan 1
Totale 9.682
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Città #
Wilmington 1.854
Houston 1.768
Woodbridge 1.452
Fairfield 355
Chandler 340
Singapore 244
Ashburn 192
Kraków 171
Rome 155
Cambridge 153
Seattle 153
Dublin 142
Ann Arbor 140
Medford 101
New York 82
Dearborn 77
Milan 63
Santa Clara 61
Lawrence 49
Jacksonville 40
Beijing 36
Engelhard 28
Moscow 24
San Diego 21
Zhengzhou 20
Creede 17
Boardman 16
Perugia 16
Menlo Park 14
Seoul 14
Center 13
Hackensack 13
Frankfurt am Main 12
London 12
Palermo 12
Bari 11
Florence 9
Norwalk 9
Turin 9
Bologna 8
Hefei 8
Council Bluffs 7
Kunming 7
Redwood City 7
Toronto 7
Washington 7
Genoa 6
Guangzhou 6
Kilburn 6
Nanchang 6
Shenzhen 6
Genova 5
Hangzhou 5
Marseille 5
Pisa 5
Vicenza 5
Bagnolo Mella 4
Brescia 4
Cagliari 4
Casorate Primo 4
Deiva Marina 4
Ferrara 4
Hong Kong 4
Munich 4
Naples 4
Paris 4
San Francisco 4
San Giovanni in Persiceto 4
Shanghai 4
The Dalles 4
Verona 4
Amsterdam 3
Barbariga 3
Bergamo 3
Bolzano 3
Campobasso 3
Chengdu 3
Civita Castellana 3
Helsinki 3
Kuching 3
Lappeenranta 3
Modena 3
Mountain View 3
Napoli 3
Nuremberg 3
Pune 3
Redditch 3
Reggio Nell'emilia 3
Salerno 3
Tokyo 3
Torino 3
Venezia 3
Venice 3
Ahmedabad 2
Alcamo 2
Ancona 2
Arona 2
Arvada 2
Azzano San Paolo 2
Billings 2
Totale 8.144
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Nome #
La mutazione di tipo A della nucleofosmina nella diagnosi e nel follow-up della leucemia mieloide acuta 637
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups 426
Comparative genomic analysis of PML and RARA breakpoints in paired diagnosis/relapse samples of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy 420
Clustering of genomic breakpoints at the MLL locus in therapy-related acute leukemia with t(4;11)(q21;q23) 416
PML–RARα kinetics and impact of FLT3–ITD mutations in newly diagnosed acute promyelocytic leukaemia treated with ATRA and ATO or ATRA and chemotherapy 415
Diagnostic refinement of chronic myeloproliferative disorders and thrombocytoses of unknown origin by multiple RT-PCR and capillary electrophoresis of BCR-ABL rearrangements and JAK2 (V617F) mutation 407
The hidden genomic landscape of acute myeloid leukemia: Subclonal structure revealed by undetected mutations 405
Clonal evolution in therapy-related neoplasms 396
Argonaute 2 sustains the gene expression program driving human monocytic differentiation of acute myeloid leukemia cells 383
Genomic analysis of therapy-related acute promyelocytic leukemias arising after malignant and non-malignant disorders 375
Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia 364
Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress 362
Erratum: Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups (Blood Cancer Journal (2013) 3 (e147) DOI:10.1038/bcj.2013.46) 335
Longitudinal detection of DNMT3AR882Htranscripts in patients with acute myeloid leukemia 315
Identification and monitoring of atypical PML/RARA fusion transcripts in acute promyelocytic leukemia 291
Prolonged treatment with arsenic trioxide (ATO) and all-trans-retinoic acid (ATRA) for relapsed acute promyelocytic leukemia previously treated with ATRA and chemotherapy 273
GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia 266
Early and sensitive detection of PML-A216V mutation by droplet digital PCR in ATO-resistant acute promyelocytic leukemia 251
The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells 229
Mutational landscape of patients with acute promyelocytic leukemia at diagnosis and relapse 223
Somatic mutations as markers of outcome after azacitidine and allogeneic stem cell transplantation in higher-risk myelodysplastic syndromes 186
WT1 evaluation in higher-risk myelodysplastic syndrome patients treated with azacitidine 183
Acute promyelocytic Leukemia: Update on the mechanisms of leukemogenesis, resistance and on innovative treatment strategies 180
MRD in AML: The Role of New Techniques 171
Impact of NPM1/FLT3-ITD genotypes defined by the2017 European LeukemiaNet in patients with acute myeloid leukemia 164
Characterization of FLT3-ITDmut acute myeloid leukemia: molecular profiling of leukemic precursor cells 140
Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML 138
Clinical relevance of an objective - limit of detection - limit of quantification - based flow cytometry approach for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial 124
Impaired dopamine- and adenosine-mediated signaling and plasticity in a novel rodent model for DYT25 dystonia 117
Use of Measurable Residual Disease to Evolve Transplant Policy in Acute Myeloid Leukemia: A 20-Year Monocentric Observation 68
CD99 as a novel therapeutic target on leukemic progenitor cells in FLT3-ITDmut AML 66
Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia 65
Clonal genetic evolution at relapse of favorable-risk acute myeloid leukemia with NPM1 mutation is associated with phenotypic changes and worse outcomes 63
ELN2017 risk stratification improves outcome prediction when applied to the prospective GIMEMA AML1310 protocol 62
From Clonal Hematopoiesis to Therapy-Related Myeloid Neoplasms: The Silent Way of Cancer Progression 61
Ascorbate Plus Buformin in AML: A Metabolic Targeted Treatment 58
MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients 55
Expression profiling of extramedullary acute myeloid leukemia suggests involvement of epithelial-mesenchymal transition pathways 52
Acute Promyelocytic Leukemia After Radium-223 Exposure for Prostate Cancer in a Chemotherapy-Naïve Patient 49
A Relapsing Meningeal Acute Myeloid Leukaemia FLT3-ITD+ Responding to Gilteritinib 46
The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia 45
Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 Protocol 45
Poly(ADP-Ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocytic leukemia: synergistic in vitro antitumor effects with hypomethylating agents or high-dose vitamin C 44
Vitamin C Deficiency in Patients With Acute Myeloid Leukemia 43
Characterization of a novel IDH2‐R159H mutation in acute myeloid leukaemia: Effects on cell metabolism and differentiation 41
When Poisons Cure: The Case of Arsenic in Acute Promyelocytic Leukemia 41
Targeting lactate metabolism by inhibiting MCT1 or MCT4 impairs leukemic cell proliferation, induces two different related death-pathways and increases chemotherapeutic sensitivity of acute myeloid leukemia cells 39
Applicability of 2022 classifications of acute myeloid leukemia in the real-world setting 39
Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis 38
Case report: very late, atypical extra-medullary relapse in a patient with acute promyelocytic leukemia (APL) rescued with a transplant-free approach 31
New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia 31
Acute myeloid leukemia with NPM1 mutation and disseminated leukaemia cutis: achievement of molecular complete remission by venetoclax/azacytidine combination in a very old patient 30
Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia 29
An Polycythemia Vera Evolve from Acute Myeloid Leukemia? Report of a Case Showing a Simultaneous Minor JAK2 V617F Mutated Clone 29
Increased Plasma Levels of lncRNAs LINC01268, GAS5 and MALAT1 Correlate with Negative Prognostic Factors in Myelofibrosis 26
The Venetoclax/Azacitidine Combination Targets the Disease Clone in Acute Myeloid Leukemia, Being Effective and Safe in a Patient with COVID-19 23
YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells 22
Risk-adapted MRD-directed therapy for young acute myeloid leukemia adults: 6-year update of the GIMEMA AML1310 trial 22
Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia 22
STAT5b-RARa-positive acute myeloid leukemia: Diagnostic and therapeutic challenges of a rare AML subtype 20
Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations 20
The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells 17
The response to oxidative damage correlates with driver mutations and clinical outcome in patients with myelofibrosis 17
Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia 14
Functional characterization and response to FLT3 inhibitors in acute myeloid leukaemia with a non-canonical FLT3 mutation: A proof of concept 12
Retinoic acid and proteotoxic stress induce AML cell death overcoming stromal cell protection 12
Diagnosis and Classification of AML: WHO 2016 7
Advances in the pathogenesis of FLT3 -mutated acute myeloid leukemia and targeted treatments 7
Totale 10.003
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Categoria #
all - tutte 28.944
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.944
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.728 0 0 0 0 184 240 309 229 241 218 146 161
2020/20211.607 144 151 171 205 197 150 196 150 62 85 74 22
2021/2022568 13 30 40 14 17 49 20 44 48 49 49 195
2022/2023975 96 67 59 129 61 174 146 58 91 15 38 41
2023/2024686 92 18 91 42 56 136 50 33 35 26 18 89
2024/2025646 87 268 143 135 13 0 0 0 0 0 0 0
Totale 10.003