IRIS
OTTONE, TIZIANA
 Distribuzione geografica
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Continente #
NA - Nord America 8.959
EU - Europa 2.456
AS - Asia 2.198
SA - Sud America 384
AF - Africa 31
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
Totale 14.039
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Nazione #
US - Stati Uniti d'America 8.896
IT - Italia 1.050
SG - Singapore 980
CN - Cina 323
BR - Brasile 317
RU - Federazione Russa 273
HK - Hong Kong 243
FR - Francia 193
PL - Polonia 193
VN - Vietnam 192
KR - Corea 178
IE - Irlanda 164
DE - Germania 147
GB - Regno Unito 108
NL - Olanda 78
JP - Giappone 71
UA - Ucraina 65
IN - India 59
FI - Finlandia 54
CA - Canada 35
SE - Svezia 32
AT - Austria 24
AR - Argentina 21
ES - Italia 21
ID - Indonesia 21
MX - Messico 19
BD - Bangladesh 15
CO - Colombia 14
IR - Iran 12
TR - Turchia 11
ZA - Sudafrica 11
IQ - Iraq 10
BE - Belgio 9
MY - Malesia 9
PH - Filippine 9
VE - Venezuela 9
PK - Pakistan 8
EC - Ecuador 7
KZ - Kazakistan 7
LT - Lituania 7
TH - Thailandia 7
CH - Svizzera 6
CL - Cile 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
HR - Croazia 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
DO - Repubblica Dominicana 4
EU - Europa 4
JO - Giordania 4
LU - Lussemburgo 4
SA - Arabia Saudita 4
BO - Bolivia 3
CZ - Repubblica Ceca 3
EG - Egitto 3
GR - Grecia 3
IL - Israele 3
KE - Kenya 3
NG - Nigeria 3
PS - Palestinian Territory 3
SN - Senegal 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
CY - Cipro 2
DZ - Algeria 2
GE - Georgia 2
HU - Ungheria 2
MA - Marocco 2
NP - Nepal 2
PE - Perù 2
PY - Paraguay 2
RO - Romania 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
BY - Bielorussia 1
CR - Costa Rica 1
DK - Danimarca 1
ET - Etiopia 1
HN - Honduras 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LV - Lettonia 1
MK - Macedonia 1
MN - Mongolia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
SD - Sudan 1
SI - Slovenia 1
SY - Repubblica araba siriana 1
Totale 14.039
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Città #
Wilmington 1.854
Houston 1.776
Woodbridge 1.452
Singapore 625
Fairfield 355
Chandler 341
Dallas 320
Ashburn 311
San Jose 258
Hong Kong 240
Rome 222
Kraków 171
Seattle 156
Cambridge 153
Dublin 145
Ann Arbor 140
Beijing 134
New York 111
Medford 101
Milan 88
Council Bluffs 82
Santa Clara 78
Dearborn 77
Ho Chi Minh City 74
The Dalles 67
Tokyo 64
Los Angeles 59
Lawrence 49
Moscow 48
Lauterbourg 44
Buffalo 41
Jacksonville 40
Hanoi 37
São Paulo 34
Engelhard 28
Frankfurt am Main 27
Helsinki 27
Perugia 24
London 23
North Bergen 23
Boardman 22
San Diego 22
Zhengzhou 21
Chennai 20
Munich 20
Warsaw 19
Creede 17
Jakarta 17
Bologna 16
Seoul 16
Menlo Park 14
Nuremberg 14
Orem 14
Center 13
Chicago 13
Denver 13
Hackensack 13
Montreal 13
Toronto 13
Amsterdam 12
Atlanta 12
Bari 12
Palermo 12
Stockholm 12
Florence 11
Naples 11
Redondo Beach 11
Columbus 10
Phoenix 10
Rio de Janeiro 10
Vienna 10
Guangzhou 9
Hefei 9
Norwalk 9
Parma 9
Turin 9
Curitiba 8
Genoa 8
Lappeenranta 8
San Francisco 8
Washington 8
Ancona 7
Baghdad 7
Brooklyn 7
Charlotte 7
Johannesburg 7
Kunming 7
Redwood City 7
Shenzhen 7
Bay Shore 6
Bogotá 6
Brussels 6
Da Nang 6
Hangzhou 6
Kilburn 6
Marseille 6
Nanchang 6
Pisa 6
Porto Alegre 6
Turku 6
Totale 10.549
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Nome #
La mutazione di tipo A della nucleofosmina nella diagnosi e nel follow-up della leucemia mieloide acuta 868
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups 470
Comparative genomic analysis of PML and RARA breakpoints in paired diagnosis/relapse samples of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy 460
Clonal evolution in therapy-related neoplasms 457
Diagnostic refinement of chronic myeloproliferative disorders and thrombocytoses of unknown origin by multiple RT-PCR and capillary electrophoresis of BCR-ABL rearrangements and JAK2 (V617F) mutation 452
Clustering of genomic breakpoints at the MLL locus in therapy-related acute leukemia with t(4;11)(q21;q23) 450
PML–RARα kinetics and impact of FLT3–ITD mutations in newly diagnosed acute promyelocytic leukaemia treated with ATRA and ATO or ATRA and chemotherapy 445
The hidden genomic landscape of acute myeloid leukemia: Subclonal structure revealed by undetected mutations 437
Argonaute 2 sustains the gene expression program driving human monocytic differentiation of acute myeloid leukemia cells 425
Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress 412
Genomic analysis of therapy-related acute promyelocytic leukemias arising after malignant and non-malignant disorders 402
Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia 401
Erratum: Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups (Blood Cancer Journal (2013) 3 (e147) DOI:10.1038/bcj.2013.46) 382
Longitudinal detection of DNMT3AR882Htranscripts in patients with acute myeloid leukemia 361
Identification and monitoring of atypical PML/RARA fusion transcripts in acute promyelocytic leukemia 340
Prolonged treatment with arsenic trioxide (ATO) and all-trans-retinoic acid (ATRA) for relapsed acute promyelocytic leukemia previously treated with ATRA and chemotherapy 318
GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia 308
Early and sensitive detection of PML-A216V mutation by droplet digital PCR in ATO-resistant acute promyelocytic leukemia 297
Mutational landscape of patients with acute promyelocytic leukemia at diagnosis and relapse 294
The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells 267
Acute promyelocytic Leukemia: Update on the mechanisms of leukemogenesis, resistance and on innovative treatment strategies 265
MRD in AML: The Role of New Techniques 246
Somatic mutations as markers of outcome after azacitidine and allogeneic stem cell transplantation in higher-risk myelodysplastic syndromes 231
Clinical relevance of an objective - limit of detection - limit of quantification - based flow cytometry approach for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial 225
WT1 evaluation in higher-risk myelodysplastic syndrome patients treated with azacitidine 215
Impact of NPM1/FLT3-ITD genotypes defined by the2017 European LeukemiaNet in patients with acute myeloid leukemia 212
Characterization of FLT3-ITDmut acute myeloid leukemia: molecular profiling of leukemic precursor cells 208
Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML 184
Impaired dopamine- and adenosine-mediated signaling and plasticity in a novel rodent model for DYT25 dystonia 178
Applicability of 2022 classifications of acute myeloid leukemia in the real-world setting 147
ELN2017 risk stratification improves outcome prediction when applied to the prospective GIMEMA AML1310 protocol 142
Vitamin C Deficiency in Patients With Acute Myeloid Leukemia 141
Use of Measurable Residual Disease to Evolve Transplant Policy in Acute Myeloid Leukemia: A 20-Year Monocentric Observation 133
Poly(ADP-Ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocytic leukemia: synergistic in vitro antitumor effects with hypomethylating agents or high-dose vitamin C 132
Acute myeloid leukemia with NPM1 mutation and disseminated leukaemia cutis: achievement of molecular complete remission by venetoclax/azacytidine combination in a very old patient 131
MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients 130
Clonal genetic evolution at relapse of favorable-risk acute myeloid leukemia with NPM1 mutation is associated with phenotypic changes and worse outcomes 130
Expression profiling of extramedullary acute myeloid leukemia suggests involvement of epithelial-mesenchymal transition pathways 127
Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia 125
A complex clinical presentation of ultra-high risk acute promyelocytic leukemia: A case report and insights on management 124
New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia 124
CD99 as a novel therapeutic target on leukemic progenitor cells in FLT3-ITDmut AML 124
Ascorbate Plus Buformin in AML: A Metabolic Targeted Treatment 121
From Clonal Hematopoiesis to Therapy-Related Myeloid Neoplasms: The Silent Way of Cancer Progression 113
Acute Promyelocytic Leukemia After Radium-223 Exposure for Prostate Cancer in a Chemotherapy-Naïve Patient 112
An Polycythemia Vera Evolve from Acute Myeloid Leukemia? Report of a Case Showing a Simultaneous Minor JAK2 V617F Mutated Clone 108
The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia 99
Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 Protocol 94
A Relapsing Meningeal Acute Myeloid Leukaemia FLT3-ITD+ Responding to Gilteritinib 90
When Poisons Cure: The Case of Arsenic in Acute Promyelocytic Leukemia 88
A fatal case of peritonitis due to colonic localization of acute myeloid leukemia 88
Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia 87
Characterization of a novel IDH2‐R159H mutation in acute myeloid leukaemia: Effects on cell metabolism and differentiation 87
Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia 84
Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis 83
Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations 82
Combination treatment of resistant acute promyelocytic leukemia cells with arsenic trioxide and anti-apoptotic gene inhibitors 78
Retinoic acid and proteotoxic stress induce AML cell death overcoming stromal cell protection 77
YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells 76
Evolution of transcriptomic profiles in relapsed inv(16) acute myeloid leukemia 75
The Venetoclax/Azacitidine Combination Targets the Disease Clone in Acute Myeloid Leukemia, Being Effective and Safe in a Patient with COVID-19 75
Targeting lactate metabolism by inhibiting MCT1 or MCT4 impairs leukemic cell proliferation, induces two different related death-pathways and increases chemotherapeutic sensitivity of acute myeloid leukemia cells 72
Case report: very late, atypical extra-medullary relapse in a patient with acute promyelocytic leukemia (APL) rescued with a transplant-free approach 69
PML::RARα+ myeloid cells display metabolic alterations that can be targeted to treat resistant/relapse acute promyelocytic leukemias 67
Advances in the pathogenesis of FLT3 -mutated acute myeloid leukemia and targeted treatments 65
Functional characterization and response to FLT3 inhibitors in acute myeloid leukaemia with a non-canonical FLT3 mutation: A proof of concept 62
STAT5b-RARa-positive acute myeloid leukemia: Diagnostic and therapeutic challenges of a rare AML subtype 59
The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells 59
Risk-adapted MRD-directed therapy for young acute myeloid leukemia adults: 6-year update of the GIMEMA AML1310 trial 57
Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia 55
Increased Plasma Levels of lncRNAs LINC01268, GAS5 and MALAT1 Correlate with Negative Prognostic Factors in Myelofibrosis 55
Diagnosis and Classification of AML: WHO 2016 50
The response to oxidative damage correlates with driver mutations and clinical outcome in patients with myelofibrosis 46
IDH1 mutation in acute lymphoblastic leukemia—A rare but significant finding 44
APL‐like subset within NPM1‐mutated AML: A distinct immunophenotype correlating with early vascular complications 9
Genomic structural variations contribute to inform prognosis in patients with cytogenetically normal acute myeloid leukemia 9
Totale 14.415
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Categoria #
all - tutte 44.745
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.745
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202196 0 0 0 0 0 0 0 0 0 0 74 22
2021/2022568 13 30 40 14 17 49 20 44 48 49 49 195
2022/2023975 96 67 59 129 61 174 146 58 91 15 38 41
2023/2024686 92 18 91 42 56 136 50 33 35 26 18 89
2024/20251.783 87 268 143 135 62 157 202 131 187 155 150 106
2025/20263.275 278 159 620 237 388 107 504 345 343 290 4 0
Totale 14.415