IRIS
OTTONE, TIZIANA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 9.154
EU - Europa 2.512
AS - Asia 2.302
SA - Sud America 385
AF - Africa 31
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
Totale 14.395
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 9.076
IT - Italia 1.104
SG - Singapore 982
CN - Cina 333
BR - Brasile 317
RU - Federazione Russa 273
HK - Hong Kong 244
FR - Francia 193
PL - Polonia 193
VN - Vietnam 193
KR - Corea 178
IE - Irlanda 164
DE - Germania 147
GB - Regno Unito 108
BD - Bangladesh 102
NL - Olanda 80
JP - Giappone 72
UA - Ucraina 65
IN - India 59
FI - Finlandia 54
CA - Canada 45
SE - Svezia 32
AT - Austria 24
ID - Indonesia 22
AR - Argentina 21
ES - Italia 21
MX - Messico 19
CO - Colombia 14
IR - Iran 12
TR - Turchia 11
ZA - Sudafrica 11
IQ - Iraq 10
MY - Malesia 10
BE - Belgio 9
PH - Filippine 9
VE - Venezuela 9
PK - Pakistan 8
CL - Cile 7
EC - Ecuador 7
KZ - Kazakistan 7
LT - Lituania 7
TH - Thailandia 7
CH - Svizzera 6
AE - Emirati Arabi Uniti 5
AU - Australia 5
HR - Croazia 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
DO - Repubblica Dominicana 4
EU - Europa 4
JM - Giamaica 4
JO - Giordania 4
LU - Lussemburgo 4
SA - Arabia Saudita 4
BO - Bolivia 3
CZ - Repubblica Ceca 3
EG - Egitto 3
GR - Grecia 3
IL - Israele 3
KE - Kenya 3
NG - Nigeria 3
PS - Palestinian Territory 3
SN - Senegal 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
CY - Cipro 2
DZ - Algeria 2
GE - Georgia 2
HU - Ungheria 2
MA - Marocco 2
NP - Nepal 2
PE - Perù 2
PY - Paraguay 2
RO - Romania 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
BY - Bielorussia 1
CR - Costa Rica 1
DK - Danimarca 1
ET - Etiopia 1
GT - Guatemala 1
HN - Honduras 1
KG - Kirghizistan 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LV - Lettonia 1
MK - Macedonia 1
MN - Mongolia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
SD - Sudan 1
SI - Slovenia 1
Totale 14.393
Salva come PNG Salva come JPEG
Città #
Wilmington 1.854
Houston 1.778
Woodbridge 1.452
Singapore 627
Fairfield 355
Chandler 341
Dallas 323
Ashburn 322
San Jose 273
Hong Kong 240
Rome 227
Kraków 171
Seattle 156
Cambridge 153
Dublin 145
Ann Arbor 142
Beijing 134
New York 124
Council Bluffs 118
Medford 101
Milan 92
Santa Clara 81
Dearborn 77
Ho Chi Minh City 74
Los Angeles 69
The Dalles 67
Tokyo 64
Buffalo 49
Lawrence 49
Moscow 48
Lauterbourg 44
Jacksonville 40
Hanoi 37
São Paulo 34
Engelhard 28
Frankfurt am Main 27
Helsinki 27
Perugia 24
London 23
North Bergen 23
Boardman 22
San Diego 22
Zhengzhou 21
Chennai 20
Munich 20
Warsaw 19
Bologna 17
Creede 17
Jakarta 17
Seoul 16
Toronto 16
Chicago 15
Denver 14
Florence 14
Menlo Park 14
Montreal 14
Naples 14
Nuremberg 14
Orem 14
Atlanta 13
Bari 13
Center 13
Hackensack 13
Palermo 13
Amsterdam 12
Stockholm 12
Columbus 11
Redondo Beach 11
Phoenix 10
Rio de Janeiro 10
Turin 10
Vienna 10
Charlotte 9
Guangzhou 9
Hefei 9
Norwalk 9
Parma 9
Brooklyn 8
Curitiba 8
Genoa 8
Lappeenranta 8
San Francisco 8
Washington 8
Ancona 7
Baghdad 7
Johannesburg 7
Kunming 7
Redwood City 7
Shenzhen 7
Bay Shore 6
Bogotá 6
Brussels 6
Da Nang 6
Hangzhou 6
Kilburn 6
Marseille 6
Nanchang 6
Pisa 6
Porto Alegre 6
Turku 6
Totale 10.685
Salva come PNG Salva come JPEG
Nome #
La mutazione di tipo A della nucleofosmina nella diagnosi e nel follow-up della leucemia mieloide acuta 896
Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups 472
Comparative genomic analysis of PML and RARA breakpoints in paired diagnosis/relapse samples of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy 460
Clonal evolution in therapy-related neoplasms 457
Clustering of genomic breakpoints at the MLL locus in therapy-related acute leukemia with t(4;11)(q21;q23) 453
Diagnostic refinement of chronic myeloproliferative disorders and thrombocytoses of unknown origin by multiple RT-PCR and capillary electrophoresis of BCR-ABL rearrangements and JAK2 (V617F) mutation 452
PML–RARα kinetics and impact of FLT3–ITD mutations in newly diagnosed acute promyelocytic leukaemia treated with ATRA and ATO or ATRA and chemotherapy 446
The hidden genomic landscape of acute myeloid leukemia: Subclonal structure revealed by undetected mutations 437
Argonaute 2 sustains the gene expression program driving human monocytic differentiation of acute myeloid leukemia cells 433
Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress 414
Genomic analysis of therapy-related acute promyelocytic leukemias arising after malignant and non-malignant disorders 403
Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia 401
Erratum: Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups (Blood Cancer Journal (2013) 3 (e147) DOI:10.1038/bcj.2013.46) 382
Longitudinal detection of DNMT3AR882Htranscripts in patients with acute myeloid leukemia 363
Identification and monitoring of atypical PML/RARA fusion transcripts in acute promyelocytic leukemia 341
Prolonged treatment with arsenic trioxide (ATO) and all-trans-retinoic acid (ATRA) for relapsed acute promyelocytic leukemia previously treated with ATRA and chemotherapy 320
GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia 309
Early and sensitive detection of PML-A216V mutation by droplet digital PCR in ATO-resistant acute promyelocytic leukemia 299
Mutational landscape of patients with acute promyelocytic leukemia at diagnosis and relapse 299
The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells 299
Acute promyelocytic Leukemia: Update on the mechanisms of leukemogenesis, resistance and on innovative treatment strategies 272
MRD in AML: The Role of New Techniques 253
Somatic mutations as markers of outcome after azacitidine and allogeneic stem cell transplantation in higher-risk myelodysplastic syndromes 233
Clinical relevance of an objective - limit of detection - limit of quantification - based flow cytometry approach for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial 230
Impact of NPM1/FLT3-ITD genotypes defined by the2017 European LeukemiaNet in patients with acute myeloid leukemia 224
WT1 evaluation in higher-risk myelodysplastic syndrome patients treated with azacitidine 217
Characterization of FLT3-ITDmut acute myeloid leukemia: molecular profiling of leukemic precursor cells 208
Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD+ AML 186
Impaired dopamine- and adenosine-mediated signaling and plasticity in a novel rodent model for DYT25 dystonia 180
Applicability of 2022 classifications of acute myeloid leukemia in the real-world setting 150
Vitamin C Deficiency in Patients With Acute Myeloid Leukemia 147
ELN2017 risk stratification improves outcome prediction when applied to the prospective GIMEMA AML1310 protocol 143
Use of Measurable Residual Disease to Evolve Transplant Policy in Acute Myeloid Leukemia: A 20-Year Monocentric Observation 139
Acute myeloid leukemia with NPM1 mutation and disseminated leukaemia cutis: achievement of molecular complete remission by venetoclax/azacytidine combination in a very old patient 137
Poly(ADP-Ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocytic leukemia: synergistic in vitro antitumor effects with hypomethylating agents or high-dose vitamin C 136
Clonal genetic evolution at relapse of favorable-risk acute myeloid leukemia with NPM1 mutation is associated with phenotypic changes and worse outcomes 134
MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs' patients 133
An Polycythemia Vera Evolve from Acute Myeloid Leukemia? Report of a Case Showing a Simultaneous Minor JAK2 V617F Mutated Clone 132
A complex clinical presentation of ultra-high risk acute promyelocytic leukemia: A case report and insights on management 129
CD99 as a novel therapeutic target on leukemic progenitor cells in FLT3-ITDmut AML 129
Expression profiling of extramedullary acute myeloid leukemia suggests involvement of epithelial-mesenchymal transition pathways 128
Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia 126
New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia 126
Ascorbate Plus Buformin in AML: A Metabolic Targeted Treatment 124
Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 Protocol 116
Acute Promyelocytic Leukemia After Radium-223 Exposure for Prostate Cancer in a Chemotherapy-Naïve Patient 113
From Clonal Hematopoiesis to Therapy-Related Myeloid Neoplasms: The Silent Way of Cancer Progression 113
The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia 105
A Relapsing Meningeal Acute Myeloid Leukaemia FLT3-ITD+ Responding to Gilteritinib 96
A fatal case of peritonitis due to colonic localization of acute myeloid leukemia 93
When Poisons Cure: The Case of Arsenic in Acute Promyelocytic Leukemia 92
Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia 89
Characterization of a novel IDH2‐R159H mutation in acute myeloid leukaemia: Effects on cell metabolism and differentiation 87
Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations 86
Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis 85
Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia 84
Combination treatment of resistant acute promyelocytic leukemia cells with arsenic trioxide and anti-apoptotic gene inhibitors 81
Retinoic acid and proteotoxic stress induce AML cell death overcoming stromal cell protection 80
YY1 Knockdown Relieves the Differentiation Block and Restores Apoptosis in AML Cells 79
Evolution of transcriptomic profiles in relapsed inv(16) acute myeloid leukemia 79
The Venetoclax/Azacitidine Combination Targets the Disease Clone in Acute Myeloid Leukemia, Being Effective and Safe in a Patient with COVID-19 78
The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells 76
Targeting lactate metabolism by inhibiting MCT1 or MCT4 impairs leukemic cell proliferation, induces two different related death-pathways and increases chemotherapeutic sensitivity of acute myeloid leukemia cells 74
PML::RARα+ myeloid cells display metabolic alterations that can be targeted to treat resistant/relapse acute promyelocytic leukemias 73
Case report: very late, atypical extra-medullary relapse in a patient with acute promyelocytic leukemia (APL) rescued with a transplant-free approach 72
Advances in the pathogenesis of FLT3 -mutated acute myeloid leukemia and targeted treatments 66
Functional characterization and response to FLT3 inhibitors in acute myeloid leukaemia with a non-canonical FLT3 mutation: A proof of concept 65
STAT5b-RARa-positive acute myeloid leukemia: Diagnostic and therapeutic challenges of a rare AML subtype 61
Risk-adapted MRD-directed therapy for young acute myeloid leukemia adults: 6-year update of the GIMEMA AML1310 trial 58
Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia 56
Increased Plasma Levels of lncRNAs LINC01268, GAS5 and MALAT1 Correlate with Negative Prognostic Factors in Myelofibrosis 55
Diagnosis and Classification of AML: WHO 2016 51
IDH1 mutation in acute lymphoblastic leukemia—A rare but significant finding 49
The response to oxidative damage correlates with driver mutations and clinical outcome in patients with myelofibrosis 48
Asciminib and pulsed ATRA as post-remission therapy in T315I mutated PML-RARA-positive blast crisis of chronic myeloid leukemia 22
Genomic structural variations contribute to inform prognosis in patients with cytogenetically normal acute myeloid leukemia 21
APL‐like subset within NPM1‐mutated AML: A distinct immunophenotype correlating with early vascular complications 19
Totale 14.774
Salva come PNG Salva come JPEG
Categoria #
all - tutte 46.816
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.816
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202122 0 0 0 0 0 0 0 0 0 0 0 22
2021/2022568 13 30 40 14 17 49 20 44 48 49 49 195
2022/2023975 96 67 59 129 61 174 146 58 91 15 38 41
2023/2024686 92 18 91 42 56 136 50 33 35 26 18 89
2024/20251.783 87 268 143 135 62 157 202 131 187 155 150 106
2025/20263.634 278 159 620 237 388 107 504 345 343 290 221 142
Totale 14.774