IRIS
RASI, GUIDO
 Distribuzione geografica
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Continente #
NA - Nord America 25.966
AS - Asia 3.134
EU - Europa 2.556
SA - Sud America 481
AF - Africa 34
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 6
Totale 32.187
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Nazione #
US - Stati Uniti d'America 25.893
SG - Singapore 1.731
CN - Cina 707
BR - Brasile 415
UA - Ucraina 410
IT - Italia 394
DE - Germania 381
HK - Hong Kong 291
IE - Irlanda 277
PL - Polonia 262
FR - Francia 204
RU - Federazione Russa 174
GB - Regno Unito 133
SE - Svezia 117
KR - Corea 114
VN - Vietnam 94
FI - Finlandia 89
CA - Canada 41
NL - Olanda 41
IN - India 40
JP - Giappone 33
AR - Argentina 25
MX - Messico 22
AT - Austria 19
BD - Bangladesh 16
UZ - Uzbekistan 16
ID - Indonesia 15
EC - Ecuador 14
IQ - Iraq 12
ES - Italia 11
ZA - Sudafrica 11
BE - Belgio 10
IR - Iran 10
TR - Turchia 9
EU - Europa 8
MA - Marocco 8
CL - Cile 7
IL - Israele 7
VE - Venezuela 7
CO - Colombia 6
CZ - Repubblica Ceca 6
SA - Arabia Saudita 6
AU - Australia 5
LT - Lituania 5
PK - Pakistan 5
RO - Romania 5
EG - Egitto 4
KE - Kenya 4
AZ - Azerbaigian 3
JO - Giordania 3
NG - Nigeria 3
OM - Oman 3
PE - Perù 3
PT - Portogallo 3
PY - Paraguay 3
TW - Taiwan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AE - Emirati Arabi Uniti 2
AL - Albania 2
CH - Svizzera 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
GR - Grecia 2
HN - Honduras 2
KZ - Kazakistan 2
LB - Libano 2
LV - Lettonia 2
MY - Malesia 2
NI - Nicaragua 2
NP - Nepal 2
PH - Filippine 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BN - Brunei Darussalam 1
DM - Dominica 1
EE - Estonia 1
GH - Ghana 1
GT - Guatemala 1
HU - Ungheria 1
LK - Sri Lanka 1
MK - Macedonia 1
PS - Palestinian Territory 1
SI - Slovenia 1
SN - Senegal 1
TV - Tuvalu 1
UY - Uruguay 1
Totale 32.187
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Città #
Woodbridge 7.567
Wilmington 7.094
Houston 5.914
Ann Arbor 757
Fairfield 621
Singapore 603
Ashburn 383
Jacksonville 380
Chandler 354
Beijing 314
Hong Kong 282
Dublin 275
Kraków 251
Seattle 237
Medford 225
Cambridge 223
Dearborn 155
Santa Clara 118
Rome 103
Lawrence 99
Los Angeles 89
The Dalles 88
Dallas 78
Hangzhou 78
Zhengzhou 73
New York 69
Mülheim 63
Buffalo 60
San Diego 45
Milan 38
São Paulo 34
Ho Chi Minh City 33
Council Bluffs 31
Moscow 27
Boardman 25
Menlo Park 25
Toronto 25
London 24
Shanghai 23
Munich 22
Nuremberg 21
Hanoi 20
Chicago 19
Falls Church 19
Hefei 19
University Park 18
Columbus 17
Nanjing 17
Verona 16
San Mateo 15
Norwalk 14
Belo Horizonte 13
Chennai 13
Redwood City 13
Rio de Janeiro 13
San Jose 13
Yongsan-gu 13
Tokyo 12
Brooklyn 11
Mountain View 11
Porto Alegre 11
Denver 10
Kunming 10
San Francisco 10
Warsaw 10
Atlanta 9
Bologna 9
Fukuoka 9
Jakarta 9
Seoul 9
Brussels 8
Curitiba 8
Guangzhou 8
Johannesburg 8
Tampa 8
Boston 7
Detroit 7
Goiânia 7
Haiphong 7
Nürnberg 7
Palo Alto 7
Redondo Beach 7
Saint Petersburg 7
Vienna 7
Brno 6
Chengdu 6
Guayaquil 6
Montreal 6
Tashkent 6
Brasília 5
Changsha 5
Helsinki 5
Mexico City 5
Nanchang 5
Redmond 5
Ridgeland 5
Stockholm 5
Turku 5
Berlin 4
Buenos Aires 4
Totale 27.494
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Nome #
Thymosin alpha 1: from bench to bedside 594
Use of thymosin alpha 1 for the preparation of a medicament for the prevention and treatment of allergies 564
Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance 528
Vaccination with a synthetic nonapeptide expressed in human tumors prevents colorectal cancer liver metastases in syngeneic rats 509
Thymosin alpha(1) in combination with cytokines and chemotherapy for the treatment of cancer 498
Survivin-Igm Immuno Complex: A Novel Candidate Biomarker Of Cirrhosis To Monitor Patients Progression Towards Hepatocellular Carcinoma 488
Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1 484
ANTITUMOR EFFECT OF COMBINED TREATMENT WITH THYMOSIN ALPHA-1 AND INTERLEUKIN-2 AFTER 5-FLUOROURACIL IN LIVER METASTASES FROM COLORECTAL-CANCER IN RATS 481
Anti-proliferative effect of atrial natriuretic peptide on colorectal cancer cells: evidence for an Akt-mediated cross-talk between NHE-1 activity and Wnt/β-catenin signaling 469
Feasibilty of in utero DNA vaccination following naked gene transfer into pig fetal muscle: transgene expression, immunity and safety 468
Combination low-dose lymphoblastoid interferon and thymosin alpha(1) therapy in the treatment of chronic hepatitis B 462
Combination therapy in the treatment of chronic viral hepatitis and prevention of hepatocellular carcinoma 460
The risks of risk aversion in drug regulation 453
Cancer drug development and the evolving regulatory framework for companion diagnostics in the European union 449
Detection of high levels of Survivin-immunoglobulin M immune complex in sera from hepatitis C virus infected patients with cirrhosis 449
Access to patient-level trial data--a boon to drug developers 446
Combined treatment with thymosin-alpha 1 and low dose interferon-alpha after dacarbazine in advanced melanoma 445
TCTP is a critical survival factor that protects cancer cells from oxidative stress-induced cell-death. 444
Nerve growth factor involvement in liver cirrhosis and hepatocellular carcinoma 437
Drug policy for an aging population--the European Medicines Agency's geriatric medicines strategy 433
Anti-tumour immunogens and vaccines 430
Treatment of aspergillus infection with thymosin alpha 1 430
Differential expression of a new tumor-associated antigen, TLP, during human colorectal cancer tumorigenesis 427
Combination low-dose lymphoblastoid interferon and thymosin α1 therapy in the treatment of chronic hepatitis B 421
Vaccination with a synthetic nonapeptide expressed in human tumors prevents colorectal cancer liver metastases in syngeneic rats 416
Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through Toll-like receptor signaling 413
The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation 413
Combination therapy with BRMs in cancer and infectious diseases 406
Sequential chemoimmunotherapy for advanced non-small cell lung cancer using cisplatin, etoposide, thymosin-alpha 1 and interferon-alpha 2a 403
Combination therapy in the treatment of chronic viral hepatitis and prevention of hepatocellular carcinoma 403
An audience with Guido Rasi. Interview by Asher Mullard 402
High doses of thymosin alpha 1 enhance the anti-tumor efficacy of combination chemo-immunotherapy for murine B16 melanoma 401
comparative cellular signal patway analysis of metastatic colorectal cancer in human and preclinical animal model 396
Microfabricated biocapsules provide short-term immunoisolation of insulinoma xenografts 390
Combination thymosin alpha(1) and lymphoblastoid interferon treatment in chronic hepatitis C 387
Thymosin alpha 1 in the treatment of cancer: from basic research to clinical application 387
Evaluation of antigen specific recognition and cell mediated cytotoxicity by a modified lysispot assay in a rat colon carcinoma model 386
null 385
up-regulation of melanocytic differentiation antigens induced by cyanidin-3-o--glucopyranoside in human melanoma cells. 385
ACTIVATION OF HUMAN ENDOGENOUS RETROVIRUS-K AND PRODUCTION OF INFECTIOUS VIRUS-LIKE PARTICLES IN HUMAN MELANOMA CELLS ABS -0153 382
Proactively managing the risk of marketed drugs: experience with the EMA Pharmacovigilance Risk Assessment Committee 381
null 380
Straight talk with...Guido Rasi. Interview by Roxanne Khamsi 380
Time to market and patient access to new oncology products in Italy: a multistep pathway from European context to regional healthcare providers 379
Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response 377
Fifty years after thalidomide; what role for drug regulators? 376
Nerve growth factor involvement in liver cirrhosis and hepatocellular carcinoma 376
differentiation therapy: in vitro evidence making cyanidin-3-o--glucopiranoside useful for prevention and treatment of melanoma 374
early detection of molecular markers suitable for colorectal cancer diagnosis and therapy in a carcinogenesis model 374
Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo 372
nerve growth factor (ngf) and cirrhosis: a possible new marker of progression to hepatocellular carcinoma (hcc) 372
COMPARATIVE CELLULAR SIGNAL PATWAY ANALYSIS OF METASTATIC COLORECTAL CANCER IN HUMAN AND PRECLINICAL ANIMAL MODEL 371
Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance. 365
Method of up-regulating tumor antigen expression using thymalfasin 364
Differentiation of human melanoma cells induced by cyanidin-3-O-beta-glucopyranoside 362
Efficacy of repeated cycles of chemo-immunotherapy with thymosin alpha 1 and interleukin-2 after intraperitoneal 5-fluorouracil delivery 360
Preclinical studies using oncofidä-s, a new sn38-hyaluronic acid bioconyugate, for cd44-targeted therapy of colon carcinoma 360
up-regulation of melan-a/mart-1 antigen expression during human melanoma cell differentiation 353
preventive peptide vaccine for colorectal cancer metastases 352
Cytoplasmic localization of anthracycline antitumor drugs conjugated with reduced glutathione: a possible correlation with multidrug resistance mechanisms 349
Characterization of four newly established melanoma cell lines 348
nerve growth factor (ngf): a possible marker for hepatocellular carcinoma (hcc)? 344
Combination therapy with thymosin alpha 1 potentiates the anti-tumor activity of interleukin-2 with cyclophosphamide in the treatment of the Lewis lung carcinoma in mice 343
null 342
Influenza della concentrazione di adriamicina su modificazioni volumetriche e proliferazione di cellule leucemiche in vitro 327
WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer 315
Rationale for therapeutic approaches with thymic hormones, interleukin 2 and interferon in combination with chemotherapy. 309
Stimolazione in vivo mediante prostaglandine ed interferone dell'attività natural killer in topi trattati con ciclofosfamide. vol. 87, p. 595-603 306
Metformin induces apoptosis and downregulates pyruvate kinase M2 in breast cancer cells only when grown in nutrient-poor conditions 243
A new tumour associated antigen of non-small cell lung cancer: Tumour Liberated Proteins (TLP) - A possible new tumor marker 238
A new tumour associated antigen of non-small cell lung cancer: Tumour liberated proteins (TLP) - A possible new tumor marker 211
Combined treatment with thymosin-alpha1 and low-dose interferon-alpha after ifosfamide in non-small cell lung cancer: A phase-II controlled trial 198
Open clinical trial data for all? A view from regulators 185
Sequential biochemotherapy for metastatic colorectal cancer using, fluorouracil, folinic acid, thymopentin and interleukin-2: Clinical and immunological effects 179
BIOCHEMOTHERAPY WITH THYMOSIN-ALPHA-1, INTERLEUKIN-2 AND DACARBAZINE IN PATIENTS WITH METASTATIC MELANOMA - CLINICAL AND IMMUNOLOGICAL EFFECTS 176
Clinical trial publications: A sufficient basis for healthcare decisions? 152
Asthma, allergy and the olympics: A 12-year survey in elite athletes 142
Are Novel, Nonrandomized Analytic Methods Fit for Decision Making? The Need for Prospective, Controlled, and Transparent Validation 138
From adaptive licensing to adaptive pathways: Delivering a flexible life-span approach to bring new drugs to patients 137
Combination therapy in the treatment of chronic viral hepatitis and prevention of hepatocellular carcinoma 134
Innovative medicines: New regulatory procedures for the third millennium 123
Expression profile of HERVs and inflammatory mediators detected in nasal mucosa as a predictive biomarker of COVID-19 severity 121
Transparency and the European medicines agency - Sharing of clinical trial data 119
Big Data – How to Realize the Promise 117
Preliminary evidence of the differential expression of human endogenous retroviruses in Kawasaki disease and SARS-CoV-2-associated multisystem inflammatory syndrome in children 115
First-in-human clinical trials - What we can learn from tragic failures 115
How aligned are the perspectives of EU regulators and HTA bodies? A comparative analysis of regulatory-HTA parallel scientific advice 114
Data Rich, Information Poor: Can We Use Electronic Health Records to Create a Learning Healthcare System for Pharmaceuticals? 114
European regulatory experience with drugs for central nervous system disorders 109
Time to Review the Role of Surrogate End Points in Health Policy: State of the Art and the Way Forward 108
The impact of parallel regulatory–health technology assessment scientific advice on clinical development. Assessing the uptake of regulatory and health technology assessment recommendations 106
preventive peptide vaccine for colorectal cancer metastases 100
Drug regulation and pricing - Can regulators influence affordability? 96
Steps forward in regulatory pathways for acute and chronic heart failure 93
Inhibitor of fatty acid amide hydrolase: learning from tragic failures [The editorialists reply] 87
High CD169 Monocyte/Lymphocyte Ratio Reflects the Immunophenotyping Disruption and Predicts Oxygen Need in COVID-19 Patients 85
High CD169 monocyte/lymphocyte ratio reflects immunophenotype disruption and oxygen need in COVID-19 patients 82
Pharmacovigilance 2030: Invited Commentary for the January 2020 “Futures” Edition of Clinical Pharmacology and Therapeutics 77
Characterization of three melanoma cell lines (TVM-A12, TVM-A-197, TVM-BO): Sensitivity to lysis and effect of retinoic acid 75
Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves 71
Totale 31.795
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Categoria #
all - tutte 74.030
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 74.030
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.169 0 0 0 0 0 606 626 436 146 127 185 43
2021/2022977 32 113 45 26 24 92 77 38 94 67 57 312
2022/20231.150 127 53 45 120 91 292 97 79 81 12 129 24
2023/2024317 40 8 31 18 30 67 11 11 2 11 13 75
2024/20252.991 69 585 319 136 51 223 121 145 256 245 441 400
2025/20261.614 320 173 449 256 334 82 0 0 0 0 0 0
Totale 32.398