Besides few data concerning the antiseptic properties against a range of microbial agents and the anti-inflammatory potential both in vitro and in vivo, little is known about the influence of Eucalyptus oil (EO) extract on the monocytic/macrophagic system, one of the primary cellular effectors of the immune response against pathogen attacks. The activities of this natural extract have mainly been recognized through clinical experience, but there have been relatively little scientific studies on its biological actions. Here we investigated whether EO extract is able to affect the phagocytic ability of human monocyte derived macrophages (MDMs) in vitro and of rat peripheral blood monocytes/granulocytes in vivo in absence or in presence of immuno-suppression induced by the chemotherapeutic agent 5-fluorouracil (5-FU).

Serafino, A., SINIBALDI VALLEBONA, P., Andreola, F., Zonfrillo, M., Mercuri, L., Federici, M., et al. (2008). Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response. BMC IMMUNOLOGY, 9, 17 [10.1186/1471-2172-9-17].

Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response

SINIBALDI VALLEBONA, PAOLA;ANDREOLA, FEDERICA;FEDERICI, MASSIMO;Rasi, G;GARACI, ENRICO;
2008-01-01

Abstract

Besides few data concerning the antiseptic properties against a range of microbial agents and the anti-inflammatory potential both in vitro and in vivo, little is known about the influence of Eucalyptus oil (EO) extract on the monocytic/macrophagic system, one of the primary cellular effectors of the immune response against pathogen attacks. The activities of this natural extract have mainly been recognized through clinical experience, but there have been relatively little scientific studies on its biological actions. Here we investigated whether EO extract is able to affect the phagocytic ability of human monocyte derived macrophages (MDMs) in vitro and of rat peripheral blood monocytes/granulocytes in vivo in absence or in presence of immuno-suppression induced by the chemotherapeutic agent 5-fluorouracil (5-FU).
2008
Pubblicato
Rilevanza internazionale
Abstract
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
Con Impact Factor ISI
Phagocytosis; Eucalyptus; Leukocytes, Mononuclear; Monoterpenes; Lymphocyte Activation; Oils, Volatile; Fluorouracil; Cell Culture Techniques; Rats; Nocodazole; Animals; Humans; Tubulin Modulators; Myeloablative Agonists; Macrophages; Cytokines; Immunity, Innate; Microscopy, Confocal
Serafino, A., SINIBALDI VALLEBONA, P., Andreola, F., Zonfrillo, M., Mercuri, L., Federici, M., et al. (2008). Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response. BMC IMMUNOLOGY, 9, 17 [10.1186/1471-2172-9-17].
Serafino, A; SINIBALDI VALLEBONA, P; Andreola, F; Zonfrillo, M; Mercuri, L; Federici, M; Rasi, G; Garaci, E; Pierimarchi, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/29911
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