Besides few data concerning the antiseptic properties against a range of microbial agents and the anti-inflammatory potential both in vitro and in vivo, little is known about the influence of Eucalyptus oil (EO) extract on the monocytic/macrophagic system, one of the primary cellular effectors of the immune response against pathogen attacks. The activities of this natural extract have mainly been recognized through clinical experience, but there have been relatively little scientific studies on its biological actions. Here we investigated whether EO extract is able to affect the phagocytic ability of human monocyte derived macrophages (MDMs) in vitro and of rat peripheral blood monocytes/granulocytes in vivo in absence or in presence of immuno-suppression induced by the chemotherapeutic agent 5-fluorouracil (5-FU).
Serafino, A., SINIBALDI VALLEBONA, P., Andreola, F., Zonfrillo, M., Mercuri, L., Federici, M., et al. (2008). Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response. BMC IMMUNOLOGY, 9, 17 [10.1186/1471-2172-9-17].
Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
SINIBALDI VALLEBONA, PAOLA;ANDREOLA, FEDERICA;FEDERICI, MASSIMO;Rasi, G;GARACI, ENRICO;
2008-01-01
Abstract
Besides few data concerning the antiseptic properties against a range of microbial agents and the anti-inflammatory potential both in vitro and in vivo, little is known about the influence of Eucalyptus oil (EO) extract on the monocytic/macrophagic system, one of the primary cellular effectors of the immune response against pathogen attacks. The activities of this natural extract have mainly been recognized through clinical experience, but there have been relatively little scientific studies on its biological actions. Here we investigated whether EO extract is able to affect the phagocytic ability of human monocyte derived macrophages (MDMs) in vitro and of rat peripheral blood monocytes/granulocytes in vivo in absence or in presence of immuno-suppression induced by the chemotherapeutic agent 5-fluorouracil (5-FU).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.