IRIS
PIERMATTEO, LORENZO
 Distribuzione geografica
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Continente #
NA - Nord America 2.176
EU - Europa 574
AS - Asia 383
OC - Oceania 81
SA - Sud America 12
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.232
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Nazione #
US - Stati Uniti d'America 2.169
SG - Singapore 319
IT - Italia 284
IE - Irlanda 99
AU - Australia 74
DE - Germania 45
FI - Finlandia 33
GB - Regno Unito 30
CN - Cina 27
RU - Federazione Russa 19
SE - Svezia 17
CZ - Repubblica Ceca 14
BE - Belgio 10
IN - India 8
CA - Canada 7
ES - Italia 7
NZ - Nuova Zelanda 7
CO - Colombia 6
FR - Francia 6
KR - Corea 6
JP - Giappone 5
VN - Vietnam 5
IQ - Iraq 4
PK - Pakistan 4
UA - Ucraina 4
AR - Argentina 3
BR - Brasile 3
CM - Camerun 3
TR - Turchia 3
CH - Svizzera 2
HK - Hong Kong 2
NL - Olanda 2
A2 - ???statistics.table.value.countryCode.A2??? 1
EE - Estonia 1
NG - Nigeria 1
RO - Romania 1
ZW - Zimbabwe 1
Totale 3.232
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Città #
Wilmington 484
Houston 304
Singapore 290
Chandler 212
Fairfield 145
Rome 105
Santa Clara 92
New York 83
Dublin 71
Woodbridge 55
Ashburn 43
Seattle 43
Cambridge 41
Ann Arbor 40
Medford 33
Milan 32
Helsinki 30
La Veta 29
Melbourne 28
Sydney 27
Engelhard 25
Cedarhurst 18
Beijing 17
Council Bluffs 17
Washington 17
Canberra 16
Lawrence 16
Moscow 14
Naples 14
St. George 13
Munich 12
San Diego 11
Creede 10
Genoa 10
Brussels 9
Nuremberg 9
Brno 8
Padova 8
Palo Alto 8
Auckland 7
Bari 6
Dearborn 6
Genzano di Roma 6
Olomouc 6
San Jose 6
Seoul 6
Albano Laziale 5
Fort Worth 5
London 5
Tokyo 5
Toronto 5
Garbagnate Milanese 4
Hanover 4
Ho Chi Minh City 4
Kilburn 4
Los Angeles 4
Baghdad 3
Birmingham 3
Bogotá 3
Campinas 3
Colorado Springs 3
Evanston 3
Guangzhou 3
Istanbul 3
Lahore 3
Lappeenranta 3
Mülheim 3
Nepi 3
New Bedfont 3
North Hollywood 3
Redwood City 3
The Dalles 3
Alcalá de Henares 2
Amsterdam 2
Bengaluru 2
Billings 2
Bollate 2
Buenos Aires 2
Burbank 2
Camponogara 2
Catania 2
Cesano Maderno 2
Chicago 2
Città Sant'Angelo 2
Hong Kong 2
Hounslow 2
Manitou Springs 2
Media 2
Menlo Park 2
Montreal 2
Newcastle upon Tyne 2
Palermo 2
Paris 2
Perugia 2
Prineville 2
Roebling 2
Roquetas de Mar 2
Southwark 2
Terni 2
Terre Haute 2
Totale 2.631
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Nome #
High rates of chronic HBV genotype E infection in a group of migrants in Italy from West Africa: Virological characteristics associated with poor immune clearance 326
HDV can constrain HBV genetic evolution in hbsag: Implications for the identification of innovative pharmacological targets 286
A snapshot of virological presentation and outcome of immunosuppression-driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection 173
A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro 169
Quantification of intrahepatic total HBV DNA in liver biopsies of HBV-infected patients by a modified version of COBAS® Ampliprep/COBAS®TaqMan HBV test v2.0 135
Establishment of a Seronegative Occult Infection With an Active Hepatitis B Virus Reservoir Enriched of Vaccine Escape Mutations in a Vaccinated Infant After Liver Transplantation 117
Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype-D infection 109
Long-Term SARS-CoV-2 Infection Associated with Viral Dissemination in Different Body Fluids Including Bile in Two Patients with Acute Cholecystitis 108
In the setting of HIV-infection, HBV-reactivation is revealed by highly sensitive assays in a conspicuous fraction of anti-HBc-positive/HBsAg-negative patients switching to Tenofovir-sparing therapy. 102
New markers in monitoring the reactivation of hepatitis B virus infection in immunocompromised hosts 91
Long-term SARS-CoV-2 infection associated with viral dissemination in different body fluids Including bile in two patients with acute cholecystitis 90
Highly Sensitive HBsAg, Anti-HBc and Anti HBsAg Titres in Early Diagnosis of HBV Reactivation in Anti-HBc-Positive Onco-Haematological Patients 89
Cryptic HBV replicative activity is frequently revealed in anti-HBC-positive/hbsag-negative patients with HIV infection by highly sensitive molecular assays, and can be predicted by integrating classical and novel serological HBV markers 82
Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment 74
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control 70
Virological reactivation of hepatitis B virus is a frequent event in anti-HBc-positive/HBsAg-negative HIV-infected patients switching to Tenofovir-sparing therapy as revealed by highly-sensitive HBV assays. 63
HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation 62
for the Icona Foundation Study Group Reactivation of hepatitis B virus is a frequent event in anti-HBc-positive/HBsAg-negative HIV-infected patients switching to Tenofovir sparing therapy as revealed by highly sensitive HBV assays. 56
Frequency of atypical mutations in the spike glycoprotein in SARS-CoV-2 circulating from July 2020 to July 2022 in central Italy: a refined analysis by Next Generation Sequencing 55
Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment 49
Impact of pre-existent drug resistance on virological efficacy of single tablet regimens in people living with HIV 46
Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B 46
SARS-CoV-2 variants and their relevant mutational profiles: update summer 2021 45
Human monocyte-derived macrophages (MDM): model 1 (GM-CSF) 42
An increase in the levels of middle surface antigen characterizes patients developing HBV-driven liver cancer despite prolonged virological suppression 41
Evaluation of HIV-DNA and residual viremia levels through week 96 in HIV-infected individuals who continue a two-drug or switch to a three-drug integrase strand transfer inhibitor-based regimen 36
Update on SARS-CoV-2 Omicron Variant of Concern and Its Peculiar Mutational Profile 36
Novel concepts on mechanisms underlying Hepatitis Delta virus persistence and related pathogenesis 35
ULTRASENSITIVE HBV-RNA QUANTIFICATION AS A PROMISING BIOMARKER TO OPTIMIZE THE STAGING OF CHRONIC HBV INFECTION AND TO DETECT MINIMAL VIRAL ACTIVITY UNDER PROLONGED VIROLOGICAL SUPPRESSION AND OCCULT HBV INFECTION. 34
Circulation of sars-cov-2 variants in central Italy: spike variability characterization by deep-sequencing. 33
HBcrAg tightly correlates with elevated HDV replicative activity and with enhanced liver inflammation and damage: role of HBcrAg as a biomarker of liver disease progression in the setting of HDV co-infection 31
The acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer in vivo, impairs HBsAg secretion and affects its structural stability in vitro 30
Acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer, hampers HBsAg stability and secretion and promotes cell survival 28
Neuro-Axonal Damage and Alteration of Blood–Brain Barrier Integrity in COVID-19 Patients 25
Hepatitis B-related hepatic flare during immune reconstitution syndrome after antiretroviral treatment initiation in an HBV surface antigen-positive patient with HIV: viroimmunological and histological characterization 24
HUMAN ENDOGENOUS RETROVIRUSES EXPRESSION CORRELATES WITH HIV RESERVOIR, LYMPHOCYTES ACTIVATION AND LOW CD4 COUNT IN VIROLOGICALLY SUPPRESSED PATIENTS 24
Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the early phases of chronic infection even in the setting of limited liver damage 24
HIV DNA viral reservoirs in blood and gut-associated lymphoid tissues (GALT): Implications of switch from triple antiretroviral therapy (ART) to 2-drug dolutegravir/lamivudine regimens 24
Hepatitis delta virus (HDV) infection : frequency and outcome in persons living with HIV (PLWH). Data from the ICONA (Italian cohort of naïve for antiretrovirals) cohort 24
The acquisition of positively charged amino acids in HBsAg C- terminus impairs HBsAg secretion, affects its structural stability and is associated with HBV-induced liver cancer 24
Ultrasensitive HBV-RNA quantification by droplet digital PCR is a promising biomarker to optimize the staging of chronic HBV infection and to identify minimal viral activity under prolonged virological suppression. 23
HDV epidemic in Central Italy is stable over the last two decades and is characterized by the circulation of multiple HDV subgenotypes 1 inducing different inflammatory stimuli 23
Transcriptionally active HBV integrations frequently occur in the early phases of chronic infection and mostly involve genetic regions crucial for cell proliferation. 23
HDV replicative activity parallels the production of the three HBsAg forms (Large, Middle and Small HBsAg) and its pathogenetic impact is exacerbated by concomitant HBV replication 22
THE ENRICHMENT OF POSITIVELY CHARGED AMINO ACIDS IN HBsAg C-TERMINUS IMPAIRS HBsAg SECRETION, AFFECTS ITS STRUCTURAL STABILITY AND IS CORRELATED WITH HBV-INDUCED LIVER CANCER. 22
The transactivation of endogenous retroviruses correlates with HIV reservoir, lymphocytes activation and low CD4 count in virologically suppressed patients 21
An in-depth characterization of VOCs circulation by using NGS analysis of the Spike protein. 21
Prevalence of HDV infection in Central Italy has remained stable across the last two decades with dominance of sub-genotypes 1 and characterized by elevated viral replication 20
Kinetics of HBsAg forms in chronic hepatitis delta patients treated with bulevirtide for 48 weeks: correlation with virological response 20
HIV-1 transmitted drug resistance in newly diagnosed individuals in Italy over the period 2015-21 20
PREVALENCE AND OUTCOME OF HEPATITIS DELTA VIRUS (HDV) INFECTION AMONG PERSONS LIVING WITH HIV (PLWH) IN ITALY: THE DELTA-ICONA STUDY OC 150 19
Stable temporal trend of HDV seroprevalence in central Italy across the last two decades with the circulation of HDV sub-genotypes 1 inducing different inflammatory stimuli 18
Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection 18
Higher levels of three HBsAg forms (Large, Middle and Small HBsAg) are associated with HDV replication and with the degree of disease and liver damage. 18
Evidence of abundant transcriptionally active HBV-integration events involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection. 17
Unexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection/quantification and vaccination strategies 16
New insights into hepatitis B virus lymphotropism: implications for HBV-related lymphomagenesis 16
Determinants of worse liver-related outcome according to HDV infection among HBsAg positive persons living with HIV: Data from the ICONA cohort 16
KINETICS OF THE THREE HBSAG ISOFORMS ALONG WITH HDV-RNA PREDICT VIROLOGICAL RESPONSE IN CHD PATIENTS TREATED WITH BULEVIRTIDE UP TO 96 WEEKS P 215 15
POTENT ANTIVIRAL ACTIVITY OF NEW GENERATION HIV-1 MATURATION INHIBITORS ON HUMAN PRIMARY CELLS 15
Serum HBsAg and ddPCR HBV-DNA as predictive parameters of HBsAg loss after nucleo (s) tide analogue (NA) treatment discontinuation in non-cirrhotic patients with Chronic Hepatitis B 15
Serum HBsAg and highly-sensitive HBV-DNA quantification can predict HBsAg loss after nucleos(t)ide analogue systematic discontinuation in non cirrhotic patients with chronic hepatitis B 13
Kinetics of the Three HBsAg Isoforms along with HDV-RNA Predict Virological Response in CHD Patients Treated with Bulevirtide for 48 Weeks 13
Utility of accessible SARS-CoV-2 specific immunoassays in vaccinated adults with a history of advanced HIV infection 13
Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus cure 11
HDV INFECTION IS STABLE IN CENTRAL ITALY ACROSS THE LAST TWO DECADES AND IS CHARACTERIZED BY THE CIRCULATION OF MULTIPLE HDV SUB-GENOTYPES 1 WITH A DIFFERENT PRO-INFLAMMATORY POTENTIAL 10
PATHWAYS UNDERLYING HDV PERSISTENCE ACT INDEPENDENTLY FROM THE EXTENT OF HBV RESEVOIR AND ARE SUSTAINED BY AN ABUNDANT PRODUCTION OF HBSAG DERIVED FROM INTEGRATED HBV-DNA P 214 10
The intrahepatic activity of Hepatitis Delta virus is sustained by an abundant production of HBs transcripts, mainly derived from integrated HBV-DNA, and is not strictly related to the extent of HBV reservoir 10
Totale 3.436
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Categoria #
all - tutte 16.573
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.573
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020400 0 0 0 29 27 42 37 32 81 52 53 47
2020/2021516 43 42 42 42 45 65 128 64 12 13 10 10
2021/2022281 15 9 0 18 10 26 27 25 93 10 2 46
2022/2023550 33 73 45 56 63 79 37 62 44 7 36 15
2023/2024751 140 16 76 50 77 89 41 12 25 134 25 66
2024/2025709 73 380 236 20 0 0 0 0 0 0 0 0
Totale 3.436