PIERMATTEO, LORENZO
PIERMATTEO, LORENZO
Dipartimento di Biologia
A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro
2020-02-23 Salpini, R; Piermatteo, L; Battisti, A; Colagrossi, L; Aragri, M; Yu La Rosa, K; Bertoli, A; Saccomandi, P; Lichtner, M; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Iapadre, N; Cerva, C; Aquaro, S; Angelico, M; Sarmati, L; Andreoni, M; Verheyen, J; Ceccherini-Silberstein, F; Levrero, M; Perno, Cf; Belloni, L; Svicher, V
A peculiar HBsAg isoforms composition characterizes chronic HDV coinfection respect to HBV mono-infection, with higher middle-/large-HBs levels paralleling HDV activity.
2024-01-01 Magnapera, A; Piermatteo, L; D’Anna, S; Olivero, A; Duca, L; Torre, G; Castelli, C; Teti, E; Di Lorenzo, A; Malagnino, V; Iannetta, M; Baiocchi, L; Francioso, S; Lenci, I; Ceccherini-Silberstein, F; Milella, M; Saracino, A; Ciancio, A; Sarmati, L; Lampertico, P; Rizzetto, M; Caviglia, Gp; Svicher, V; Salpini., R
A snapshot of virological presentation and outcome of immunosuppression-driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection
2019-07-26 Salpini, R; Battisti, A; Colagrossi, L; Di Carlo, D; Fabeni, L; Piermatteo, L; Cerva, C; Lichtner, M; Mastroianni, C; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Angelico, M; Sarmati, L; Andreoni, M; Perno, C-; Ceccherini-Silberstein, F; Svicher, V
Acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer, hampers HBsAg stability and secretion and promotes cell survival
2022-01-01 Piermatteo, L; Carioti, L; Leoni, G; Duca, L; Saccomandi, P; Stella, D; Andreassi, E; Bertoli, A; Cappiello, G; Fleury, H; Svicher, V; Salpini, R
An in-depth characterization of VOCs circulation by using NGS analysis of the Spike protein.
2022-01-01 Bellocchi, Mc; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; Ceccherini-Silberstein, F
An increase in the levels of middle surface antigen characterizes patients developing HBV-driven liver cancer despite prolonged virological suppression
2021-04-02 Brancaccio, G; Salpini, R; Piermatteo, L; Surdo, M; Fini, V; Colagrossi, L; Cantone, M; Battisti, A; Oda, Y; Di Carlo, D; Ceccherini-Silberstein, F; Perno, Cf; Gaeta, Gb; Svicher, V
Biological and clinical significance of classic and innovative virological parameters in the pathogenesis and in the clinical management of HBV infection
2019-01-01 Piermatteo, L
Chronic HDV coinfection (CHD) is characterized by a different HBsAg isoforms composition respect to HBV mono-infection with higher middle- and large-HBs levels paralleling the replicative and cytolytic activity of HDV.
2024-01-01 Magnapera, 1a; Piermatteo, L; D’Anna, S; Olivero, A; Duca, L; Torre, G; Castelli, C; Teti, E; Di Lorenzo, A; Malagnino, V; Iannetta, M; Baiocchi, L; Francioso, S; Lenci, I; Ceccherini-Silberstein, F; Milella, M; Saracino, A; Ciancio, A; Sarmati, L; Lampertico, P; Rizzetto, M; Caviglia, G; Salpini, R; Svicher, V
Chronic HDV coinfection is characterized by a peculiar HBsAg isoforms composition respect to HBV mono-infection, with higher middle-/large-HBs levels paralleling HDV activity.
2024-01-01 Magnapera, A; Piermatteo, L; D’Anna, S; Olivero, A; Duca, L; Torre, G; Castelli, C; Teti, E; Di Lorenzo, A; Malagnino, V; Iannetta, M; Baiocchi, L; Francioso, S; Lenci, I; Ceccherini-Silberstein, F; Milella, M; Saracino, A; Ciancio, A; Sarmati, L; Lampertico, P; Rizzetto, M; Caviglia, G; Svicher, V; Salpini, R
Chronic HDV infection is sustained by an intense HBsAg production fromintegrated HBVDNA in the setting of a limited or even absent HBV reservoir.
2024-01-01 Salpini, 1r; D'Anna, S; Piermatteo, L; Brancaccio, G; Teti, E; Di Lorenzo, A; Grossi, I; Torre, G; Malagnino, V; Iannetta, M; Ceccherini-Silberstein, F; Pasquazzi, C; Cillo, U; Vitale, A; Gringeri, E; Magrofuoco, M; Pacenti, M; Baiocchi, L; Francioso, S; Lenci, I; Koffas, A; Geretti, A; Abate, Ml; Olivero, A; Gaeta, G; Sarmati, L; Rizzetto, M; Gill, U; Kennedy, P; Caviglia, Gp; Svicher., V
Circulation of sars-cov-2 variants in central Italy: spike variability characterization by deep-sequencing.
2022-01-01 Bellocchi, M; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; CECCHERINI SILBERSTEIN, F
Cryptic HBV activity is frequently observed among anti-HBc positive/HBsAg negative people living with HIV infection during HBV-active art and can jeopardize the full control of HIV replication.
2024-01-01 Piermatteo, L; Salpini, R; D’Anna, S; Castelli, C; Grossi, I; Mulas, T; Di Lorenzo, A; Bertoli, A; Iannetta, M; Sarmati, L; Svicher, V; Malagnino., V
Cryptic HBV replicative activity is frequently revealed in anti-HBC-positive/hbsag-negative patients with HIV infection by highly sensitive molecular assays, and can be predicted by integrating classical and novel serological HBV markers
2020-01-01 Salpini, R; Malagnino, V; Piermatteo, L; Mulas, T; Alkhatib, M; Scutari, R; Teti, E; Cerva, C; Yu La Rosa, K; Brugneti, M; Bertoli, A; Rossi, B; Holzmayer, V; Gersch, J; Kuhns, M; Cloherty, G; Ceccherini Silberstein, F; Perno, C; Iannetta, M; Andreoni, M; Sarmati, L; Svicher, V
Determinants of worse liver-related outcome according to HDV infection among HBsAg positive persons living with HIV: Data from the ICONA cohort
2024-02-01 d'Arminio Monforte, A; Tavelli, A; Salpini, R; Piermatteo, L; D'Anna, S; Carrara, S; Malagnino, V; Mazzotta, V; Brancaccio, G; Marchetti, Gc; Rosselli Del Turco, E; Rossotti, R; Mussini, C; Antinori, A; Lo Caputo, S; Ceccherini Silberstein, F; Gaeta, Gb; Svicher, V; Puoti, M
Different diagnostic performances of HDV RNA quantification assays used in clinical practicein Italy: results from a national quality control multicenter study.
2024-01-01 Salpini, 7r; Piermatteo, L; Caviglia, Gp; Bertoli, A; Brunetto, Mr; Bruzzone, B; Callegaro, A; Caudai, C; Cavallone, D; Chessa, L; Coghe, F; Coppola, N; Cuomo, N; D'Anna, S; Di Stefano, M; Duca, L; Facchetti, F; Farina, C; Ferraro, D; Franchin, E; Francisci, D; Galli, S; Garbuglia, Ar; Gennari, W; Ghisetti, V; Lampertico, P; Marascio, N; Menzo, S; Micheli, V; Niro, G; Olivero, A; Paba, P; Palermo, Ci; Palmieri, O; Paolucci, S; Pisaturo, M; Pollicino, T; Raffa, G; Torre, G; Turriziani, O; Uzzau, S; Vatteroni, M; Zazzi, M; Craxì, A; Ceccherini-Silberstein, F; Svicher On Behalf Of The Virology Italian Network Vironet C., V
Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment
2022-01-01 Piermatteo, L; Scutari, R; Chirichiello, R; Alkhatib, M; Malagnino, V; Bertoli, A; Iapadre, N; Ciotti, M; Sarmati, L; Andreoni, M; Ceccherini Silberstein, F; Salpini, R; Svicher, V
Establishment of a Seronegative Occult Infection With an Active Hepatitis B Virus Reservoir Enriched of Vaccine Escape Mutations in a Vaccinated Infant After Liver Transplantation
2019-11-06 Salpini, R; Pietrobattista, A; Piermatteo, L; Basso, Ms; Bellocchi, Mc; Liccardo, D; Carioti, L; Francalanci, P; Aragri, M; Alkhatib, M; Scutari, R; Candusso, M; Ciotti, M; Svicher, V
Evaluation of HIV-DNA and residual viremia levels through week 96 in HIV-infected individuals who continue a two-drug or switch to a three-drug integrase strand transfer inhibitor-based regimen
2023-03-03 Scutari, R; Galli, L; Alteri, C; Poli, A; Piermatteo, L; Bigoloni, A; Perno, Cf; Lazzarin, A; Ceccherini-Silberstein, F; Castagna, A; Santoro, M; Gianotti, N
Evidence of abundant transcriptionally active HBV-integration events involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection.
2022-01-01 D’Anna, S; Salpini, R; Carioti, L; Battisti, A; Piermatteo, L; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Svicher, V; Kennedy, Ptf
Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the early phases of chronic infection even in the setting of limited liver damage
2022-01-01 D’Anna, S; Carioti, L; Piermatteo, L; Battisti, A; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Kennedy, Ptf; Svicher, V; Salpini, R
| Data di pubblicazione | Titolo | Autore(i) | Tipo | File |
|---|---|---|---|---|
| 23-feb-2020 | A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro | Salpini, R; Piermatteo, L; Battisti, A; Colagrossi, L; Aragri, M; Yu La Rosa, K; Bertoli, A; Saccomandi, P; Lichtner, M; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Iapadre, N; Cerva, C; Aquaro, S; Angelico, M; Sarmati, L; Andreoni, M; Verheyen, J; Ceccherini-Silberstein, F; Levrero, M; Perno, Cf; Belloni, L; Svicher, V | Articolo su rivista | |
| 1-gen-2024 | A peculiar HBsAg isoforms composition characterizes chronic HDV coinfection respect to HBV mono-infection, with higher middle-/large-HBs levels paralleling HDV activity. | Magnapera, A; Piermatteo, L; D’Anna, S; Olivero, A; Duca, L; Torre, G; Castelli, C; Teti, E; Di Lorenzo, A; Malagnino, V; Iannetta, M; Baiocchi, L; Francioso, S; Lenci, I; Ceccherini-Silberstein, F; Milella, M; Saracino, A; Ciancio, A; Sarmati, L; Lampertico, P; Rizzetto, M; Caviglia, Gp; Svicher, V; Salpini., R | Intervento a convegno | |
| 26-lug-2019 | A snapshot of virological presentation and outcome of immunosuppression-driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection | Salpini, R; Battisti, A; Colagrossi, L; Di Carlo, D; Fabeni, L; Piermatteo, L; Cerva, C; Lichtner, M; Mastroianni, C; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Angelico, M; Sarmati, L; Andreoni, M; Perno, C-; Ceccherini-Silberstein, F; Svicher, V | Articolo su rivista | |
| 1-gen-2022 | Acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer, hampers HBsAg stability and secretion and promotes cell survival | Piermatteo, L; Carioti, L; Leoni, G; Duca, L; Saccomandi, P; Stella, D; Andreassi, E; Bertoli, A; Cappiello, G; Fleury, H; Svicher, V; Salpini, R | Articolo su rivista | |
| 1-gen-2022 | An in-depth characterization of VOCs circulation by using NGS analysis of the Spike protein. | Bellocchi, Mc; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; Ceccherini-Silberstein, F | Intervento a convegno | |
| 2-apr-2021 | An increase in the levels of middle surface antigen characterizes patients developing HBV-driven liver cancer despite prolonged virological suppression | Brancaccio, G; Salpini, R; Piermatteo, L; Surdo, M; Fini, V; Colagrossi, L; Cantone, M; Battisti, A; Oda, Y; Di Carlo, D; Ceccherini-Silberstein, F; Perno, Cf; Gaeta, Gb; Svicher, V | Articolo su rivista | |
| 1-gen-2019 | Biological and clinical significance of classic and innovative virological parameters in the pathogenesis and in the clinical management of HBV infection | Piermatteo, L | Tesi di dottorato | |
| 1-gen-2024 | Chronic HDV coinfection (CHD) is characterized by a different HBsAg isoforms composition respect to HBV mono-infection with higher middle- and large-HBs levels paralleling the replicative and cytolytic activity of HDV. | Magnapera, 1a; Piermatteo, L; D’Anna, S; Olivero, A; Duca, L; Torre, G; Castelli, C; Teti, E; Di Lorenzo, A; Malagnino, V; Iannetta, M; Baiocchi, L; Francioso, S; Lenci, I; Ceccherini-Silberstein, F; Milella, M; Saracino, A; Ciancio, A; Sarmati, L; Lampertico, P; Rizzetto, M; Caviglia, G; Salpini, R; Svicher, V | Intervento a convegno | |
| 1-gen-2024 | Chronic HDV coinfection is characterized by a peculiar HBsAg isoforms composition respect to HBV mono-infection, with higher middle-/large-HBs levels paralleling HDV activity. | Magnapera, A; Piermatteo, L; D’Anna, S; Olivero, A; Duca, L; Torre, G; Castelli, C; Teti, E; Di Lorenzo, A; Malagnino, V; Iannetta, M; Baiocchi, L; Francioso, S; Lenci, I; Ceccherini-Silberstein, F; Milella, M; Saracino, A; Ciancio, A; Sarmati, L; Lampertico, P; Rizzetto, M; Caviglia, G; Svicher, V; Salpini, R | Intervento a convegno | |
| 1-gen-2024 | Chronic HDV infection is sustained by an intense HBsAg production fromintegrated HBVDNA in the setting of a limited or even absent HBV reservoir. | Salpini, 1r; D'Anna, S; Piermatteo, L; Brancaccio, G; Teti, E; Di Lorenzo, A; Grossi, I; Torre, G; Malagnino, V; Iannetta, M; Ceccherini-Silberstein, F; Pasquazzi, C; Cillo, U; Vitale, A; Gringeri, E; Magrofuoco, M; Pacenti, M; Baiocchi, L; Francioso, S; Lenci, I; Koffas, A; Geretti, A; Abate, Ml; Olivero, A; Gaeta, G; Sarmati, L; Rizzetto, M; Gill, U; Kennedy, P; Caviglia, Gp; Svicher., V | Intervento a convegno | |
| 1-gen-2022 | Circulation of sars-cov-2 variants in central Italy: spike variability characterization by deep-sequencing. | Bellocchi, M; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; CECCHERINI SILBERSTEIN, F | Articolo su rivista | |
| 1-gen-2024 | Cryptic HBV activity is frequently observed among anti-HBc positive/HBsAg negative people living with HIV infection during HBV-active art and can jeopardize the full control of HIV replication. | Piermatteo, L; Salpini, R; D’Anna, S; Castelli, C; Grossi, I; Mulas, T; Di Lorenzo, A; Bertoli, A; Iannetta, M; Sarmati, L; Svicher, V; Malagnino., V | Intervento a convegno | |
| 1-gen-2020 | Cryptic HBV replicative activity is frequently revealed in anti-HBC-positive/hbsag-negative patients with HIV infection by highly sensitive molecular assays, and can be predicted by integrating classical and novel serological HBV markers | Salpini, R; Malagnino, V; Piermatteo, L; Mulas, T; Alkhatib, M; Scutari, R; Teti, E; Cerva, C; Yu La Rosa, K; Brugneti, M; Bertoli, A; Rossi, B; Holzmayer, V; Gersch, J; Kuhns, M; Cloherty, G; Ceccherini Silberstein, F; Perno, C; Iannetta, M; Andreoni, M; Sarmati, L; Svicher, V | Articolo su rivista | |
| 1-feb-2024 | Determinants of worse liver-related outcome according to HDV infection among HBsAg positive persons living with HIV: Data from the ICONA cohort | d'Arminio Monforte, A; Tavelli, A; Salpini, R; Piermatteo, L; D'Anna, S; Carrara, S; Malagnino, V; Mazzotta, V; Brancaccio, G; Marchetti, Gc; Rosselli Del Turco, E; Rossotti, R; Mussini, C; Antinori, A; Lo Caputo, S; Ceccherini Silberstein, F; Gaeta, Gb; Svicher, V; Puoti, M | Articolo su rivista | |
| 1-gen-2024 | Different diagnostic performances of HDV RNA quantification assays used in clinical practicein Italy: results from a national quality control multicenter study. | Salpini, 7r; Piermatteo, L; Caviglia, Gp; Bertoli, A; Brunetto, Mr; Bruzzone, B; Callegaro, A; Caudai, C; Cavallone, D; Chessa, L; Coghe, F; Coppola, N; Cuomo, N; D'Anna, S; Di Stefano, M; Duca, L; Facchetti, F; Farina, C; Ferraro, D; Franchin, E; Francisci, D; Galli, S; Garbuglia, Ar; Gennari, W; Ghisetti, V; Lampertico, P; Marascio, N; Menzo, S; Micheli, V; Niro, G; Olivero, A; Paba, P; Palermo, Ci; Palmieri, O; Paolucci, S; Pisaturo, M; Pollicino, T; Raffa, G; Torre, G; Turriziani, O; Uzzau, S; Vatteroni, M; Zazzi, M; Craxì, A; Ceccherini-Silberstein, F; Svicher On Behalf Of The Virology Italian Network Vironet C., V | Intervento a convegno | |
| 1-gen-2022 | Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment | Piermatteo, L; Scutari, R; Chirichiello, R; Alkhatib, M; Malagnino, V; Bertoli, A; Iapadre, N; Ciotti, M; Sarmati, L; Andreoni, M; Ceccherini Silberstein, F; Salpini, R; Svicher, V | Articolo su rivista | |
| 6-nov-2019 | Establishment of a Seronegative Occult Infection With an Active Hepatitis B Virus Reservoir Enriched of Vaccine Escape Mutations in a Vaccinated Infant After Liver Transplantation | Salpini, R; Pietrobattista, A; Piermatteo, L; Basso, Ms; Bellocchi, Mc; Liccardo, D; Carioti, L; Francalanci, P; Aragri, M; Alkhatib, M; Scutari, R; Candusso, M; Ciotti, M; Svicher, V | Articolo su rivista | |
| 3-mar-2023 | Evaluation of HIV-DNA and residual viremia levels through week 96 in HIV-infected individuals who continue a two-drug or switch to a three-drug integrase strand transfer inhibitor-based regimen | Scutari, R; Galli, L; Alteri, C; Poli, A; Piermatteo, L; Bigoloni, A; Perno, Cf; Lazzarin, A; Ceccherini-Silberstein, F; Castagna, A; Santoro, M; Gianotti, N | Articolo su rivista | |
| 1-gen-2022 | Evidence of abundant transcriptionally active HBV-integration events involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection. | D’Anna, S; Salpini, R; Carioti, L; Battisti, A; Piermatteo, L; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Svicher, V; Kennedy, Ptf | Intervento a convegno | |
| 1-gen-2022 | Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the early phases of chronic infection even in the setting of limited liver damage | D’Anna, S; Carioti, L; Piermatteo, L; Battisti, A; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Kennedy, Ptf; Svicher, V; Salpini, R | Intervento a convegno |