PIERMATTEO, LORENZO
PIERMATTEO, LORENZO
Dipartimento di Biologia
A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro
2020-02-23 Salpini, R; Piermatteo, L; Battisti, A; Colagrossi, L; Aragri, M; Yu La Rosa, K; Bertoli, A; Saccomandi, P; Lichtner, M; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Iapadre, N; Cerva, C; Aquaro, S; Angelico, M; Sarmati, L; Andreoni, M; Verheyen, J; Ceccherini-Silberstein, F; Levrero, M; Perno, Cf; Belloni, L; Svicher, V
A snapshot of virological presentation and outcome of immunosuppression-driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection
2019-07-26 Salpini, R; Battisti, A; Colagrossi, L; Di Carlo, D; Fabeni, L; Piermatteo, L; Cerva, C; Lichtner, M; Mastroianni, C; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Angelico, M; Sarmati, L; Andreoni, M; Perno, C-; Ceccherini-Silberstein, F; Svicher, V
Acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer, hampers HBsAg stability and secretion and promotes cell survival
2022-01-01 Piermatteo, L; Carioti, L; Leoni, G; Duca, L; Saccomandi, P; Stella, D; Andreassi, E; Bertoli, A; Cappiello, G; Fleury, H; Svicher, V; Salpini, R
An in-depth characterization of VOCs circulation by using NGS analysis of the Spike protein.
2022-01-01 Bellocchi, Mc; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; Ceccherini-Silberstein, F
An increase in the levels of middle surface antigen characterizes patients developing HBV-driven liver cancer despite prolonged virological suppression
2021-04-02 Brancaccio, G; Salpini, R; Piermatteo, L; Surdo, M; Fini, V; Colagrossi, L; Cantone, M; Battisti, A; Oda, Y; Di Carlo, D; Ceccherini-Silberstein, F; Perno, Cf; Gaeta, Gb; Svicher, V
Circulation of sars-cov-2 variants in central Italy: spike variability characterization by deep-sequencing.
2022-01-01 Bellocchi, M; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; Ceccherini-Silberstein., F
Cryptic HBV replicative activity is frequently revealed in anti-HBC-positive/hbsag-negative patients with HIV infection by highly sensitive molecular assays, and can be predicted by integrating classical and novel serological HBV markers
2020-01-01 Salpini, R; Malagnino, V; Piermatteo, L; Mulas, T; Alkhatib, M; Scutari, R; Teti, E; Cerva, C; La Rosa, Ky; Brugneti, M; Bertoli, A; Rossi, B; Holzmayer, V; Gersch, J; Kuhns, M; Cloherty, G; Ceccherini-Silberstein, F; Perno, C-; Iannetta, M; Andreoni, M; Sarmati, L; Svicher, V
Determinants of worse liver-related outcome according to HDV infection among HBsAg positive persons living with HIV: Data from the ICONA cohort
2024-02-01 d'Arminio Monforte, A; Tavelli, A; Salpini, R; Piermatteo, L; D'Anna, S; Carrara, S; Malagnino, V; Mazzotta, V; Brancaccio, G; Marchetti, Gc; Rosselli Del Turco, E; Rossotti, R; Mussini, C; Antinori, A; Lo Caputo, S; Ceccherini Silberstein, F; Gaeta, Gb; Svicher, V; Puoti, M
Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment
2021-01-01 Piermatteo, L; Scutari, R; Chirichiello, R; Alkhatib, M; Malagnino, V; Bertoli, A; Iapadre, N; Ciotti, M; Sarmati, L; Andreoni, M; Ceccherini Silberstein, F; Salpini, R; Svicher, V
Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment
2022-05-14 Piermatteo, L; Scutari, R; Chirichiello, R; Alkhatib, M; Malagnino, V; Bertoli, A; Iapadre, N; Ciotti, M; Sarmati, L; Andreoni, M; Ceccherini-Silberstein, F; Salpini, R; Svicher, V
Establishment of a Seronegative Occult Infection With an Active Hepatitis B Virus Reservoir Enriched of Vaccine Escape Mutations in a Vaccinated Infant After Liver Transplantation
2019-11-06 Salpini, R; Pietrobattista, A; Piermatteo, L; Basso, Ms; Bellocchi, Mc; Liccardo, D; Carioti, L; Francalanci, P; Aragri, M; Alkhatib, M; Scutari, R; Candusso, M; Ciotti, M; Svicher, V
Evaluation of HIV-DNA and residual viremia levels through week 96 in HIV-infected individuals who continue a two-drug or switch to a three-drug integrase strand transfer inhibitor-based regimen
2023-03-03 Scutari, R; Galli, L; Alteri, C; Poli, A; Piermatteo, L; Bigoloni, A; Perno, Cf; Lazzarin, A; Ceccherini-Silberstein, F; Castagna, A; Santoro, M; Gianotti, N
Evidence of abundant transcriptionally active HBV-integration events involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection.
2022-01-01 D’Anna, S; Salpini, R; Carioti, L; Battisti, A; Piermatteo, L; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Svicher, V; Kennedy, Ptf
Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the early phases of chronic infection even in the setting of limited liver damage
2022-01-01 D’Anna, S; Carioti, L; Piermatteo, L; Battisti, A; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Kennedy, Ptf; Svicher, V; Salpini, R
Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection
2022-01-01 Salpini, R; Carioti, L; Battisti, A; Piermatteo, L; Benedetti, L; Ceccherini-Silberstein, F; Gill, U; Svicher, V; Kennedy, P
for the Icona Foundation Study Group Reactivation of hepatitis B virus is a frequent event in anti-HBc-positive/HBsAg-negative HIV-infected patients switching to Tenofovir sparing therapy as revealed by highly sensitive HBV assays.
2022-01-01 Salpini, R; D’Anna, S; Alkhatib, M; Piermatteo, L; Tavelli, A; Quiros, E; Cingolani, A; Papalini, C; Carrara, S; Malagnino, V; Puoti, M; Sarmati, L; D’Arminio Monforte, A; Ceccherini Silberstein, F; Svicher, V
Frequency of atypical mutations in the spike glycoprotein in SARS-CoV-2 circulating from July 2020 to July 2022 in central Italy: a refined analysis by Next Generation Sequencing
2023-01-01 Bellocchi, Mc; Scutari, R; Carioti, L; Iannetta, M; Marchegiani, G; Piermatteo, L; Coppola, L; Tedde, S; Duca, L; Malagnino, V; Ansaldo, L; Braccialarghe, N; D′Anna, S; Mercedes Santoro, M; DI LORENZO, A; Salpini, R; Teti, E; Svicher, V; Andreoni, M; Sarmati, L; Ceccherini-Silberstein, F
HBcrAg tightly correlates with elevated HDV replicative activity and with enhanced liver inflammation and damage: role of HBcrAg as a biomarker of liver disease progression in the setting of HDV co-infection
2022-01-01 Salpini, R; Piermatteo, L; U, G; Battisti, A; Alkathib, M; D'Anna, S; Scutari, R; Andreassi, E; Ho, K; Ceccherini-Silberstein, F; Usai, C; Kennedy, P; Svicher, V
HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation
2021-01-01 Piermatteo, L; Mohammad, A; Stefano, D; Vincenzo, M; Bertoli, A; Eleonora, A; Elisa, B; Alessandra, I; Maria De Cristofaro, ; Giuseppina, C; Carlotta, C; Carmine, M; Mariantonietta, P; Mario, S; Nicola, C; Fontana, C; Grelli, S; CECCHERINI SILBERSTEIN, F; Andreoni, M; Gill, Us; Kennedy, Ptf; Sarmati, L; Salpini, R; Svicher, V
HDV can constrain HBV genetic evolution in hbsag: Implications for the identification of innovative pharmacological targets
2018-07-09 Colagrossi, L; Salpini, R; Scutari, R; Carioti, L; Battisti, A; Piermatteo, L; Bertoli, A; Fabeni, L; Minichini, C; Trimoulet, P; Fleury, H; Nebuloso, E; De Cristofaro, M; Cappiello, G; Spano, A; Malagnino, V; Mari, T; Barlattani, A; Iapadre, N; Lichtner, M; Mastroianni, C; Lenci, I; Pasquazzi, C; De Sanctis, Gm; Lanza, Ag; Stanzione, M; Stornaiuolo, G; Marignani, M; Sarmati, L; Andreoni, M; Angelico, M; Ceccherini-Silberstein, F; Perno, C-; Coppola, N; Svicher, V
| Data di pubblicazione | Titolo | Autore(i) | Tipo | File |
|---|---|---|---|---|
| 23-feb-2020 | A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro | Salpini, R; Piermatteo, L; Battisti, A; Colagrossi, L; Aragri, M; Yu La Rosa, K; Bertoli, A; Saccomandi, P; Lichtner, M; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Iapadre, N; Cerva, C; Aquaro, S; Angelico, M; Sarmati, L; Andreoni, M; Verheyen, J; Ceccherini-Silberstein, F; Levrero, M; Perno, Cf; Belloni, L; Svicher, V | Articolo su rivista | |
| 26-lug-2019 | A snapshot of virological presentation and outcome of immunosuppression-driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection | Salpini, R; Battisti, A; Colagrossi, L; Di Carlo, D; Fabeni, L; Piermatteo, L; Cerva, C; Lichtner, M; Mastroianni, C; Marignani, M; Maylin, S; Delaugerre, C; Morisco, F; Coppola, N; Marrone, A; Angelico, M; Sarmati, L; Andreoni, M; Perno, C-; Ceccherini-Silberstein, F; Svicher, V | Articolo su rivista | |
| 1-gen-2022 | Acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer, hampers HBsAg stability and secretion and promotes cell survival | Piermatteo, L; Carioti, L; Leoni, G; Duca, L; Saccomandi, P; Stella, D; Andreassi, E; Bertoli, A; Cappiello, G; Fleury, H; Svicher, V; Salpini, R | Articolo su rivista | |
| 1-gen-2022 | An in-depth characterization of VOCs circulation by using NGS analysis of the Spike protein. | Bellocchi, Mc; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; Ceccherini-Silberstein, F | Intervento a convegno | |
| 2-apr-2021 | An increase in the levels of middle surface antigen characterizes patients developing HBV-driven liver cancer despite prolonged virological suppression | Brancaccio, G; Salpini, R; Piermatteo, L; Surdo, M; Fini, V; Colagrossi, L; Cantone, M; Battisti, A; Oda, Y; Di Carlo, D; Ceccherini-Silberstein, F; Perno, Cf; Gaeta, Gb; Svicher, V | Articolo su rivista | |
| 1-gen-2022 | Circulation of sars-cov-2 variants in central Italy: spike variability characterization by deep-sequencing. | Bellocchi, M; Carioti, L; Scutari, R; Iannetta, M; Piermatteo, L; Alkhatib, M; Tedde, S; Duca, L; Coppola, L; Malagnino, V; Crea, A; Ansaldo, L; D’Anna, S; Santoro, Mm; Bertoli, A; Di Lorenzo, A; Salpini, R; Svicher, V; Teti, E; Braccialarghe, N; Cavasio, Ra; Sarmati, L; Andreoni, M; Ceccherini-Silberstein., F | Articolo su rivista | |
| 1-gen-2020 | Cryptic HBV replicative activity is frequently revealed in anti-HBC-positive/hbsag-negative patients with HIV infection by highly sensitive molecular assays, and can be predicted by integrating classical and novel serological HBV markers | Salpini, R; Malagnino, V; Piermatteo, L; Mulas, T; Alkhatib, M; Scutari, R; Teti, E; Cerva, C; La Rosa, Ky; Brugneti, M; Bertoli, A; Rossi, B; Holzmayer, V; Gersch, J; Kuhns, M; Cloherty, G; Ceccherini-Silberstein, F; Perno, C-; Iannetta, M; Andreoni, M; Sarmati, L; Svicher, V | Articolo su rivista | |
| 1-feb-2024 | Determinants of worse liver-related outcome according to HDV infection among HBsAg positive persons living with HIV: Data from the ICONA cohort | d'Arminio Monforte, A; Tavelli, A; Salpini, R; Piermatteo, L; D'Anna, S; Carrara, S; Malagnino, V; Mazzotta, V; Brancaccio, G; Marchetti, Gc; Rosselli Del Turco, E; Rossotti, R; Mussini, C; Antinori, A; Lo Caputo, S; Ceccherini Silberstein, F; Gaeta, Gb; Svicher, V; Puoti, M | Articolo su rivista | |
| 1-gen-2021 | Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment | Piermatteo, L; Scutari, R; Chirichiello, R; Alkhatib, M; Malagnino, V; Bertoli, A; Iapadre, N; Ciotti, M; Sarmati, L; Andreoni, M; Ceccherini Silberstein, F; Salpini, R; Svicher, V | Articolo su rivista | |
| 14-mag-2022 | Droplet digital PCR assay as an innovative and promising highly sensitive assay to unveil residual and cryptic HBV replication in peripheral compartment | Piermatteo, L; Scutari, R; Chirichiello, R; Alkhatib, M; Malagnino, V; Bertoli, A; Iapadre, N; Ciotti, M; Sarmati, L; Andreoni, M; Ceccherini-Silberstein, F; Salpini, R; Svicher, V | Articolo su rivista | |
| 6-nov-2019 | Establishment of a Seronegative Occult Infection With an Active Hepatitis B Virus Reservoir Enriched of Vaccine Escape Mutations in a Vaccinated Infant After Liver Transplantation | Salpini, R; Pietrobattista, A; Piermatteo, L; Basso, Ms; Bellocchi, Mc; Liccardo, D; Carioti, L; Francalanci, P; Aragri, M; Alkhatib, M; Scutari, R; Candusso, M; Ciotti, M; Svicher, V | Articolo su rivista | |
| 3-mar-2023 | Evaluation of HIV-DNA and residual viremia levels through week 96 in HIV-infected individuals who continue a two-drug or switch to a three-drug integrase strand transfer inhibitor-based regimen | Scutari, R; Galli, L; Alteri, C; Poli, A; Piermatteo, L; Bigoloni, A; Perno, Cf; Lazzarin, A; Ceccherini-Silberstein, F; Castagna, A; Santoro, M; Gianotti, N | Articolo su rivista | |
| 1-gen-2022 | Evidence of abundant transcriptionally active HBV-integration events involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection. | D’Anna, S; Salpini, R; Carioti, L; Battisti, A; Piermatteo, L; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Svicher, V; Kennedy, Ptf | Intervento a convegno | |
| 1-gen-2022 | Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the early phases of chronic infection even in the setting of limited liver damage | D’Anna, S; Carioti, L; Piermatteo, L; Battisti, A; Benedetti, L; Ceccherini-Silberstein, F; Gill, Us; Kennedy, Ptf; Svicher, V; Salpini, R | Intervento a convegno | |
| 1-gen-2022 | Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection | Salpini, R; Carioti, L; Battisti, A; Piermatteo, L; Benedetti, L; Ceccherini-Silberstein, F; Gill, U; Svicher, V; Kennedy, P | Articolo su rivista | |
| 1-gen-2022 | for the Icona Foundation Study Group Reactivation of hepatitis B virus is a frequent event in anti-HBc-positive/HBsAg-negative HIV-infected patients switching to Tenofovir sparing therapy as revealed by highly sensitive HBV assays. | Salpini, R; D’Anna, S; Alkhatib, M; Piermatteo, L; Tavelli, A; Quiros, E; Cingolani, A; Papalini, C; Carrara, S; Malagnino, V; Puoti, M; Sarmati, L; D’Arminio Monforte, A; Ceccherini Silberstein, F; Svicher, V | Intervento a convegno | |
| 1-gen-2023 | Frequency of atypical mutations in the spike glycoprotein in SARS-CoV-2 circulating from July 2020 to July 2022 in central Italy: a refined analysis by Next Generation Sequencing | Bellocchi, Mc; Scutari, R; Carioti, L; Iannetta, M; Marchegiani, G; Piermatteo, L; Coppola, L; Tedde, S; Duca, L; Malagnino, V; Ansaldo, L; Braccialarghe, N; D′Anna, S; Mercedes Santoro, M; DI LORENZO, A; Salpini, R; Teti, E; Svicher, V; Andreoni, M; Sarmati, L; Ceccherini-Silberstein, F | Articolo su rivista | |
| 1-gen-2022 | HBcrAg tightly correlates with elevated HDV replicative activity and with enhanced liver inflammation and damage: role of HBcrAg as a biomarker of liver disease progression in the setting of HDV co-infection | Salpini, R; Piermatteo, L; U, G; Battisti, A; Alkathib, M; D'Anna, S; Scutari, R; Andreassi, E; Ho, K; Ceccherini-Silberstein, F; Usai, C; Kennedy, P; Svicher, V | Articolo su rivista | |
| 1-gen-2021 | HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation | Piermatteo, L; Mohammad, A; Stefano, D; Vincenzo, M; Bertoli, A; Eleonora, A; Elisa, B; Alessandra, I; Maria De Cristofaro, ; Giuseppina, C; Carlotta, C; Carmine, M; Mariantonietta, P; Mario, S; Nicola, C; Fontana, C; Grelli, S; CECCHERINI SILBERSTEIN, F; Andreoni, M; Gill, Us; Kennedy, Ptf; Sarmati, L; Salpini, R; Svicher, V | Articolo su rivista | |
| 9-lug-2018 | HDV can constrain HBV genetic evolution in hbsag: Implications for the identification of innovative pharmacological targets | Colagrossi, L; Salpini, R; Scutari, R; Carioti, L; Battisti, A; Piermatteo, L; Bertoli, A; Fabeni, L; Minichini, C; Trimoulet, P; Fleury, H; Nebuloso, E; De Cristofaro, M; Cappiello, G; Spano, A; Malagnino, V; Mari, T; Barlattani, A; Iapadre, N; Lichtner, M; Mastroianni, C; Lenci, I; Pasquazzi, C; De Sanctis, Gm; Lanza, Ag; Stanzione, M; Stornaiuolo, G; Marignani, M; Sarmati, L; Andreoni, M; Angelico, M; Ceccherini-Silberstein, F; Perno, C-; Coppola, N; Svicher, V | Articolo su rivista |