The metabolic influence of gut microbiota plays a pivotal role in the pathogenesis of cardiometabolic diseases. Antibiotics affect intestinal bacterial diversity, and long-term usage has been identified as an independent risk factor for atherosclerosis-driven events. The aim of this study was to explore the interaction between gut dysbiosis by antibiotics and metabolic pathways with the impact on atherosclerosis development.
Kappel, B.a., De Angelis, L., Heiser, M., Ballanti, M., Stoehr, R., Goettsch, C., et al. (2020). Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment. MOLECULAR METABOLISM, 36 [10.1016/j.molmet.2020.100976].
Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment
Kappel, Ben ArpadInvestigation
;De Angelis, Lorenzo;Ballanti, Marta;Stoehr, Robert;Mavilio, Maria;Monteleone, GiovanniMembro del Collaboration Group
;Menghini, Rossella;Federici, Massimo
Conceptualization
2020-03-13
Abstract
The metabolic influence of gut microbiota plays a pivotal role in the pathogenesis of cardiometabolic diseases. Antibiotics affect intestinal bacterial diversity, and long-term usage has been identified as an independent risk factor for atherosclerosis-driven events. The aim of this study was to explore the interaction between gut dysbiosis by antibiotics and metabolic pathways with the impact on atherosclerosis development.| File | Dimensione | Formato | |
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