Hematopoietic cell transplantation (HCT) provides a curative therapy for severe forms of primary immunodeficiencies (PID). While the timing and extent of T-cell reconstitution following transplant for PID has been studied in depth, less is known about the kinetics of B-cell development and long-term restoration of humoral functions, which been often reported to be suboptimal after HCT.
Scarselli, A., DI CESARE, S., Capponi, C., Cascioli, F., Romiti, M.l., DI MATTEO, G., et al. (2015). Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency. JOURNAL OF CLINICAL IMMUNOLOGY, 35(4), 373-383 [10.1007/s10875-015-0154-4].
Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency
DI CESARE, SILVIA;CASCIOLI, FRANCESCA;ROMITI, MARIA LUISA;DI MATTEO, GIGLIOLA;SIMONETTI, ALESSANDRA;Palma, P;FINOCCHI, ANDREA;PALUMBO, GIUSEPPE;ROSSI, PAOLO;CANCRINI, CATERINA;AIUTI, ALESSANDRO
2015-01-01
Abstract
Hematopoietic cell transplantation (HCT) provides a curative therapy for severe forms of primary immunodeficiencies (PID). While the timing and extent of T-cell reconstitution following transplant for PID has been studied in depth, less is known about the kinetics of B-cell development and long-term restoration of humoral functions, which been often reported to be suboptimal after HCT.| File | Dimensione | Formato | |
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