IRIS
TUNDO, GRAZIA RAFFAELLA
 Distribuzione geografica
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Continente #
NA - Nord America 11.119
AS - Asia 1.886
EU - Europa 1.527
SA - Sud America 294
AF - Africa 37
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 2
Totale 14.867
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Nazione #
US - Stati Uniti d'America 11.044
SG - Singapore 840
CN - Cina 413
IT - Italia 344
BR - Brasile 245
RU - Federazione Russa 206
DE - Germania 193
VN - Vietnam 170
HK - Hong Kong 163
IE - Irlanda 121
FR - Francia 118
UA - Ucraina 107
FI - Finlandia 105
GB - Regno Unito 85
SE - Svezia 69
BD - Bangladesh 65
JP - Giappone 64
PL - Polonia 54
CA - Canada 47
NL - Olanda 47
KR - Corea 46
ID - Indonesia 29
IN - India 21
ZA - Sudafrica 20
BE - Belgio 18
MX - Messico 17
TR - Turchia 16
AR - Argentina 15
AT - Austria 14
EC - Ecuador 10
ES - Italia 10
CL - Cile 9
PK - Pakistan 9
CZ - Repubblica Ceca 8
PH - Filippine 7
IQ - Iraq 6
UZ - Uzbekistan 6
JM - Giamaica 5
KE - Kenya 5
AE - Emirati Arabi Uniti 4
LT - Lituania 4
PY - Paraguay 4
RO - Romania 4
SI - Slovenia 4
AZ - Azerbaigian 3
CO - Colombia 3
DK - Danimarca 3
GR - Grecia 3
IR - Iran 3
JO - Giordania 3
SA - Arabia Saudita 3
TN - Tunisia 3
VE - Venezuela 3
BO - Bolivia 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
EG - Egitto 2
EU - Europa 2
IL - Israele 2
LB - Libano 2
MA - Marocco 2
MD - Moldavia 2
OM - Oman 2
PT - Portogallo 2
TH - Thailandia 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
KG - Kirghizistan 1
KH - Cambogia 1
KZ - Kazakistan 1
MK - Macedonia 1
MN - Mongolia 1
MT - Malta 1
MY - Malesia 1
NG - Nigeria 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PE - Perù 1
PS - Palestinian Territory 1
PW - Palau 1
QA - Qatar 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
SL - Sierra Leone 1
SN - Senegal 1
UY - Uruguay 1
Totale 14.867
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Città #
Wilmington 2.897
Houston 2.152
Woodbridge 2.102
Singapore 526
Fairfield 442
Ashburn 346
Chandler 237
Ann Arbor 232
San Jose 220
Seattle 198
New York 171
Cambridge 168
Hong Kong 159
Beijing 143
Council Bluffs 138
Rome 133
The Dalles 126
Dublin 110
Medford 93
Jacksonville 91
Dearborn 77
Los Angeles 73
Santa Clara 71
Helsinki 70
Dallas 66
Tokyo 48
Lawrence 42
Ho Chi Minh City 40
Kraków 39
Chicago 38
Buffalo 37
Hanoi 33
Lauterbourg 33
Moscow 32
Munich 30
Xi'an 28
São Paulo 27
La Veta 25
Menlo Park 25
San Diego 25
Jakarta 22
Orem 22
Salt Lake City 20
San Francisco 20
Milan 17
Phoenix 17
Hefei 16
London 16
Nuremberg 16
Brussels 15
Johannesburg 15
Warsaw 15
Denver 14
Brooklyn 13
Montreal 13
Seoul 13
Stockholm 13
Lappeenranta 12
Poplar 12
Toronto 12
Frankfurt am Main 11
Redondo Beach 11
Rio de Janeiro 11
Atlanta 9
Guangzhou 9
Mülheim 9
Nanjing 9
Redwood City 9
Amsterdam 8
Boardman 8
Huludao 8
Manchester 8
Mexico City 8
North Bergen 8
Dong Ket 7
Istanbul 7
Mountain View 7
Nürnberg 7
Shanghai 7
Washington 7
Arnesano 6
Biên Hòa 6
Brno 6
Center 6
Chennai 6
Falls Church 6
Haiphong 6
Hải Dương 6
Kunming 6
Manila 6
Sterling 6
Chengdu 5
Da Nang 5
Hangzhou 5
Nairobi 5
Nanchang 5
Norwalk 5
Pittsburgh 5
Quảng Ninh 5
San Mateo 5
Totale 12.135
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Nome #
Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes 508
Copper(I) and copper(II) inhibit Abeta peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease 503
Role of metalloproteinases in tendon pathophysiology. 503
Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity 489
Proteasome activity is affected by fluctuations in insulin-degrading enzyme distribution 489
Oxygen exchange and energy metabolism in erythrocytes of Rett syndrome and their relationships with respiratory alterations 487
Effect of cisplatin on proteasome activity 485
Warfarin modulates the nitrite reductase activity of ferrous human serum heme-albumin. 466
Reciprocal allosteric modulation of carbon monoxide and warfarin binding to ferrous human serum heme-albumin. 454
Functional and structural roles of the N-terminal extension in Methanosarcina acetivorans protoglobin 449
Somatostatin Modulates Insulin-Degrading-Enzyme Metabolism: Implications for the Regulation of Microglia Activity in AD 445
Metal ions affect insulin-degrading enzyme activity 439
Evidence for pH-dependent multiple conformers in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding. 439
Evidence for pH-dependent multiple conformesrs in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding 426
Novel Platinum(II) compounds modulate insulin‑degrading enzyme activity and induce cell death in neuroblastoma cells. 421
Electrostatic Map of Proteasome α-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding 410
Nitrosylation Mechanisms of Mycobacterium tuberculosis and Campylobacter jejuni Truncated Hemoglobins N, O, and P. 407
Ibuprofen and warfarin modulate allosterically ferrous human serum heme-albumin nitrosylation 405
Multiple functions of insulin-degrading enzyme: a metabolic crosslight? 311
Enzyme catalysis: the case of the prostate-specific antigen 302
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S 282
Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin 281
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome 255
The proteasome as a druggable target with multiple therapeutic potentialities: cutting and non-cutting edges 254
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations 251
Effects of oral administration of common antioxidant supplements on the energy metabolism of red blood cells. Attenuation of oxidative stress-induced changes in Rett syndrome erythrocytes by CoQ10 249
null 243
Insulin-degrading enzyme (IDE): A novel heat shock-like protein 237
On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment 235
The double faced role of copper in Aβ homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration 234
Functional and spectroscopic characterization of Chlamydomonas reinhardtii truncated hemoglobins 187
Cationic porphyrins are tunable gatekeepers of the 20S proteasome 182
Insights into Proteasome Conformation Dynamics and Intersubunit Communication 179
Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells 179
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo 178
Ferric nitrosylated myoglobin catalyzes peroxynitrite scavenging 169
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: novel insights into its pro-proteostatic effect 156
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways 153
Kinetics of cyanide and carbon monoxide dissociation from ferrous human haptoglobin:hemoglobin(II) complexes 141
Pyrazolones activate the proteasome by gating mechanisms and protect neuronal cells from β-amyloid toxicity 139
At the cutting edge against cancer: A perspective on immunoproteasome and immune checkpoints modulation as a potential therapeutic intervention 136
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects 132
The nitrite reductase activity of ferrous human hemoglobin:haptoglobin 1-1 and 2-2 complexes 132
A novel and atypical NF-KB pro-inflammatory program regulated by a CamKII-proteasome axis is involved in the early activation of Muller glia by high glucose 121
Author Correction: Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome (Scientific Reports, (2017), 7, 1, (12297), 10.1038/s41598-017-12069-0) 105
The interplay between lipid and Aβ amyloid homeostasis in Alzheimer's disease: risk factors and therapeutic opportunities 103
Insulin-degrading enzyme is a non proteasomal target of carfilzomib and affects the 20S proteasome inhibition by the drug 100
Dexamethasone downregulates autophagy through accelerated turn-over of the ulk-1 complex in a trabecular meshwork cells strain: Insights on steroid-induced glaucoma pathogenesis 91
A Novel Lactobacillus brevis Fermented with a Vegetable Substrate (AL0035) Counteracts TNBS-Induced Colitis by Modulating the Gut Microbiota Composition and Intestinal Barrier 83
Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches 83
Eye Diseases: When the Solution Comes from Plant Alkaloids 82
High-glucose stimulation triggers early transcription of a panel of proinflammatory mediators in rat Muller glia cells and retina primary explants 82
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells’ Ubiquitylome 76
Corrigendum to “Silybins are stereospecific regulators of the 20S proteasome” [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813)) 76
Modulation of the 20S proteasome activity by porphyrin derivatives is steered through their charge distribution 72
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome 72
Silybins are stereospecific regulators of the 20S proteasome 71
The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design 71
Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects 69
Targeting immunoproteasome in neurodegeneration: a glance to the future 62
The Interplay Between the Ubiquitin-Proteasome System and Oxidative Stress: A Future Perspective in Eye Diseases 61
Hydroxylamine-induced oxidation of ferrous nitrobindins 61
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome 57
Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study 57
Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics 47
SpectraSage unveils specific proteolytic patterns of 20S on mono-ubiquitylated Tau proteoforms involved in neurodegeneration 31
null 9
Totale 15.164
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Categoria #
all - tutte 41.318
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.318
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202128 0 0 0 0 0 0 0 0 0 0 0 28
2021/2022565 37 77 45 25 18 35 34 20 45 32 39 158
2022/2023576 55 49 16 74 57 120 60 49 43 8 35 10
2023/2024384 82 8 10 7 23 145 12 19 13 10 0 55
2024/20251.538 37 284 139 110 76 120 125 87 96 185 200 79
2025/20262.976 190 165 343 285 276 152 410 317 290 290 246 12
Totale 15.164