IRIS
TUNDO, GRAZIA RAFFAELLA
 Distribuzione geografica
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Continente #
NA - Nord America 12.040
AS - Asia 1.996
EU - Europa 1.641
SA - Sud America 312
Continente sconosciuto - Info sul continente non disponibili 300
AF - Africa 38
OC - Oceania 2
Totale 16.329
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Nazione #
US - Stati Uniti d'America 11.920
SG - Singapore 843
IT - Italia 429
CN - Cina 428
BR - Brasile 252
RU - Federazione Russa 206
DE - Germania 194
VN - Vietnam 173
HK - Hong Kong 164
BD - Bangladesh 142
IE - Irlanda 123
FR - Francia 118
UA - Ucraina 107
FI - Finlandia 105
GB - Regno Unito 92
SE - Svezia 79
CA - Canada 69
JP - Giappone 65
PL - Polonia 56
KR - Corea 49
NL - Olanda 48
ID - Indonesia 29
IN - India 21
MX - Messico 20
ZA - Sudafrica 20
TR - Turchia 19
BE - Belgio 18
AR - Argentina 15
AT - Austria 14
CR - Costa Rica 11
EC - Ecuador 11
ES - Italia 11
CL - Cile 9
CO - Colombia 9
PK - Pakistan 9
CZ - Repubblica Ceca 8
JM - Giamaica 7
PH - Filippine 7
VE - Venezuela 7
IQ - Iraq 6
LT - Lituania 6
UZ - Uzbekistan 6
AE - Emirati Arabi Uniti 5
KE - Kenya 5
DK - Danimarca 4
NI - Nicaragua 4
PY - Paraguay 4
RO - Romania 4
SA - Arabia Saudita 4
SI - Slovenia 4
AZ - Azerbaigian 3
DO - Repubblica Dominicana 3
GR - Grecia 3
IR - Iran 3
JO - Giordania 3
TH - Thailandia 3
TN - Tunisia 3
BO - Bolivia 2
EG - Egitto 2
EU - Europa 2
HT - Haiti 2
IL - Israele 2
KZ - Kazakistan 2
LB - Libano 2
MA - Marocco 2
MD - Moldavia 2
OM - Oman 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CH - Svizzera 1
CW - ???statistics.table.value.countryCode.CW??? 1
DZ - Algeria 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
KG - Kirghizistan 1
KH - Cambogia 1
MK - Macedonia 1
MN - Mongolia 1
MT - Malta 1
MY - Malesia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PE - Perù 1
PS - Palestinian Territory 1
PW - Palau 1
QA - Qatar 1
SC - Seychelles 1
SL - Sierra Leone 1
SN - Senegal 1
UY - Uruguay 1
Totale 16.032
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Città #
Wilmington 2.898
Houston 2.154
Woodbridge 2.102
Singapore 527
Ashburn 476
Fairfield 442
San Jose 294
Chandler 237
Ann Arbor 232
Seattle 201
Council Bluffs 187
New York 180
Cambridge 168
Hong Kong 160
Beijing 143
Rome 140
The Dalles 135
Dublin 110
Los Angeles 94
Medford 93
Jacksonville 91
Santa Clara 82
Dearborn 77
Dallas 73
Helsinki 70
Tokyo 49
Buffalo 43
Chicago 42
Ho Chi Minh City 42
Lawrence 42
Kraków 39
Hanoi 34
Lauterbourg 33
Moscow 32
Denver 31
Munich 30
São Paulo 28
Xi'an 28
Milan 27
San Diego 26
La Veta 25
Menlo Park 25
San Francisco 24
Phoenix 23
Jakarta 22
Orem 22
North Bergen 21
Salt Lake City 20
Hefei 16
London 16
Montreal 16
Nuremberg 16
Brussels 15
Johannesburg 15
Seoul 15
Warsaw 15
Brooklyn 14
Stockholm 13
Toronto 13
Lappeenranta 12
Poplar 12
Springfield 12
Frankfurt am Main 11
Naples 11
Redondo Beach 11
Rio de Janeiro 11
Atlanta 10
Boardman 10
Boston 10
Mexico City 10
Washington 10
Guangzhou 9
Mülheim 9
Nanjing 9
Redwood City 9
San José 9
Amsterdam 8
Huludao 8
Manchester 8
Dong Ket 7
Istanbul 7
Las Vegas 7
Mountain View 7
Nürnberg 7
Saint Augustine 7
Shanghai 7
Arnesano 6
Biên Hòa 6
Brno 6
Center 6
Chennai 6
Columbus 6
Falls Church 6
Haiphong 6
Hải Dương 6
Kunming 6
Manila 6
Miami 6
Sterling 6
Tampa 6
Totale 12.570
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Nome #
Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes 538
Copper(I) and copper(II) inhibit Abeta peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease 534
Role of metalloproteinases in tendon pathophysiology. 522
Oxygen exchange and energy metabolism in erythrocytes of Rett syndrome and their relationships with respiratory alterations 508
Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity 507
Proteasome activity is affected by fluctuations in insulin-degrading enzyme distribution 502
Effect of cisplatin on proteasome activity 499
Warfarin modulates the nitrite reductase activity of ferrous human serum heme-albumin. 476
Evidence for pH-dependent multiple conformers in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding. 469
Reciprocal allosteric modulation of carbon monoxide and warfarin binding to ferrous human serum heme-albumin. 469
Metal ions affect insulin-degrading enzyme activity 459
Functional and structural roles of the N-terminal extension in Methanosarcina acetivorans protoglobin 459
Somatostatin Modulates Insulin-Degrading-Enzyme Metabolism: Implications for the Regulation of Microglia Activity in AD 458
Evidence for pH-dependent multiple conformesrs in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding 441
Novel Platinum(II) compounds modulate insulin‑degrading enzyme activity and induce cell death in neuroblastoma cells. 440
Electrostatic Map of Proteasome α-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding 432
Ibuprofen and warfarin modulate allosterically ferrous human serum heme-albumin nitrosylation 422
Nitrosylation Mechanisms of Mycobacterium tuberculosis and Campylobacter jejuni Truncated Hemoglobins N, O, and P. 422
Multiple functions of insulin-degrading enzyme: a metabolic crosslight? 331
Enzyme catalysis: the case of the prostate-specific antigen 318
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S 306
Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin 295
The proteasome as a druggable target with multiple therapeutic potentialities: cutting and non-cutting edges 295
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations 278
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome 272
Effects of oral administration of common antioxidant supplements on the energy metabolism of red blood cells. Attenuation of oxidative stress-induced changes in Rett syndrome erythrocytes by CoQ10 265
Insulin-degrading enzyme (IDE): A novel heat shock-like protein 257
On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment 249
null 243
The double faced role of copper in Aβ homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration 242
Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells 197
Functional and spectroscopic characterization of Chlamydomonas reinhardtii truncated hemoglobins 194
Cationic porphyrins are tunable gatekeepers of the 20S proteasome 192
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo 188
Insights into Proteasome Conformation Dynamics and Intersubunit Communication 187
Ferric nitrosylated myoglobin catalyzes peroxynitrite scavenging 187
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: novel insights into its pro-proteostatic effect 174
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways 170
Kinetics of cyanide and carbon monoxide dissociation from ferrous human haptoglobin:hemoglobin(II) complexes 160
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects 153
At the cutting edge against cancer: A perspective on immunoproteasome and immune checkpoints modulation as a potential therapeutic intervention 152
Pyrazolones activate the proteasome by gating mechanisms and protect neuronal cells from β-amyloid toxicity 146
The nitrite reductase activity of ferrous human hemoglobin:haptoglobin 1-1 and 2-2 complexes 141
A novel and atypical NF-KB pro-inflammatory program regulated by a CamKII-proteasome axis is involved in the early activation of Muller glia by high glucose 137
Insulin-degrading enzyme is a non proteasomal target of carfilzomib and affects the 20S proteasome inhibition by the drug 122
The interplay between lipid and Aβ amyloid homeostasis in Alzheimer's disease: risk factors and therapeutic opportunities 121
Author Correction: Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome (Scientific Reports, (2017), 7, 1, (12297), 10.1038/s41598-017-12069-0) 118
A Novel Lactobacillus brevis Fermented with a Vegetable Substrate (AL0035) Counteracts TNBS-Induced Colitis by Modulating the Gut Microbiota Composition and Intestinal Barrier 116
High-glucose stimulation triggers early transcription of a panel of proinflammatory mediators in rat Muller glia cells and retina primary explants 110
Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches 108
Dexamethasone downregulates autophagy through accelerated turn-over of the ulk-1 complex in a trabecular meshwork cells strain: Insights on steroid-induced glaucoma pathogenesis 102
Eye Diseases: When the Solution Comes from Plant Alkaloids 101
The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design 99
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells’ Ubiquitylome 96
Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects 95
Modulation of the 20S proteasome activity by porphyrin derivatives is steered through their charge distribution 91
Silybins are stereospecific regulators of the 20S proteasome 89
Corrigendum to “Silybins are stereospecific regulators of the 20S proteasome” [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813)) 88
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome 87
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome 79
Targeting immunoproteasome in neurodegeneration: a glance to the future 77
The Interplay Between the Ubiquitin-Proteasome System and Oxidative Stress: A Future Perspective in Eye Diseases 77
Hydroxylamine-induced oxidation of ferrous nitrobindins 73
Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study 71
Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics 68
SpectraSage unveils specific proteolytic patterns of 20S on mono-ubiquitylated Tau proteoforms involved in neurodegeneration 46
null 9
Totale 16.329
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Categoria #
all - tutte 45.716
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.716
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022406 0 0 0 25 18 35 34 20 45 32 39 158
2022/2023576 55 49 16 74 57 120 60 49 43 8 35 10
2023/2024384 82 8 10 7 23 145 12 19 13 10 0 55
2024/20251.538 37 284 139 110 76 120 125 87 96 185 200 79
2025/20263.110 190 165 343 285 276 152 410 317 290 290 246 146
2026/20271.031 193 163 428 247 0 0 0 0 0 0 0 0
Totale 16.329