IRIS
TUNDO, GRAZIA RAFFAELLA
 Distribuzione geografica
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Continente #
NA - Nord America 10.927
AS - Asia 1.814
EU - Europa 1.474
SA - Sud America 294
AF - Africa 37
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 2
Totale 14.550
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Nazione #
US - Stati Uniti d'America 10.867
SG - Singapore 830
CN - Cina 404
IT - Italia 295
BR - Brasile 245
RU - Federazione Russa 206
DE - Germania 193
VN - Vietnam 170
HK - Hong Kong 159
IE - Irlanda 121
FR - Francia 118
UA - Ucraina 107
FI - Finlandia 105
GB - Regno Unito 85
SE - Svezia 69
JP - Giappone 64
PL - Polonia 54
KR - Corea 46
NL - Olanda 43
CA - Canada 36
ID - Indonesia 29
IN - India 21
ZA - Sudafrica 20
BE - Belgio 18
BD - Bangladesh 16
MX - Messico 16
TR - Turchia 16
AR - Argentina 15
AT - Austria 14
EC - Ecuador 10
ES - Italia 10
CL - Cile 9
PK - Pakistan 9
CZ - Repubblica Ceca 8
PH - Filippine 7
IQ - Iraq 6
UZ - Uzbekistan 6
KE - Kenya 5
AE - Emirati Arabi Uniti 4
LT - Lituania 4
PY - Paraguay 4
RO - Romania 4
SI - Slovenia 4
AZ - Azerbaigian 3
CO - Colombia 3
DK - Danimarca 3
GR - Grecia 3
IR - Iran 3
JM - Giamaica 3
JO - Giordania 3
SA - Arabia Saudita 3
TN - Tunisia 3
VE - Venezuela 3
BO - Bolivia 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
EG - Egitto 2
EU - Europa 2
IL - Israele 2
LB - Libano 2
MA - Marocco 2
MD - Moldavia 2
OM - Oman 2
PT - Portogallo 2
TH - Thailandia 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
GA - Gabon 1
GY - Guiana 1
HU - Ungheria 1
KG - Kirghizistan 1
KH - Cambogia 1
KZ - Kazakistan 1
MK - Macedonia 1
MN - Mongolia 1
MT - Malta 1
MY - Malesia 1
NG - Nigeria 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PE - Perù 1
PS - Palestinian Territory 1
PW - Palau 1
QA - Qatar 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
SL - Sierra Leone 1
SN - Senegal 1
UY - Uruguay 1
Totale 14.550
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Città #
Wilmington 2.897
Houston 2.152
Woodbridge 2.102
Singapore 523
Fairfield 442
Ashburn 338
Chandler 237
Ann Arbor 232
San Jose 211
Seattle 194
Cambridge 168
New York 160
Hong Kong 155
Beijing 142
Rome 128
The Dalles 126
Dublin 110
Council Bluffs 106
Medford 93
Jacksonville 91
Dearborn 77
Helsinki 70
Los Angeles 69
Santa Clara 69
Dallas 65
Tokyo 48
Lawrence 42
Ho Chi Minh City 40
Kraków 39
Chicago 37
Buffalo 35
Hanoi 33
Lauterbourg 33
Moscow 32
Munich 30
Xi'an 28
São Paulo 27
La Veta 25
Menlo Park 25
San Diego 25
Jakarta 22
Orem 22
Salt Lake City 20
San Francisco 19
Hefei 16
London 16
Nuremberg 16
Brussels 15
Johannesburg 15
Phoenix 15
Warsaw 15
Milan 14
Denver 13
Seoul 13
Stockholm 13
Brooklyn 12
Lappeenranta 12
Poplar 12
Frankfurt am Main 11
Redondo Beach 11
Rio de Janeiro 11
Toronto 11
Montreal 10
Guangzhou 9
Mülheim 9
Nanjing 9
Redwood City 9
Amsterdam 8
Boardman 8
Huludao 8
Manchester 8
North Bergen 8
Dong Ket 7
Istanbul 7
Mexico City 7
Mountain View 7
Nürnberg 7
Arnesano 6
Atlanta 6
Biên Hòa 6
Brno 6
Center 6
Chennai 6
Falls Church 6
Haiphong 6
Hải Dương 6
Kunming 6
Manila 6
Shanghai 6
Sterling 6
Chengdu 5
Da Nang 5
Nairobi 5
Nanchang 5
Norwalk 5
Pittsburgh 5
Quảng Ninh 5
San Mateo 5
Turku 5
Washington 5
Totale 12.029
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Nome #
Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes 503
Role of metalloproteinases in tendon pathophysiology. 500
Copper(I) and copper(II) inhibit Abeta peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease 493
Proteasome activity is affected by fluctuations in insulin-degrading enzyme distribution 484
Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity 483
Effect of cisplatin on proteasome activity 483
Oxygen exchange and energy metabolism in erythrocytes of Rett syndrome and their relationships with respiratory alterations 481
Warfarin modulates the nitrite reductase activity of ferrous human serum heme-albumin. 464
Reciprocal allosteric modulation of carbon monoxide and warfarin binding to ferrous human serum heme-albumin. 449
Functional and structural roles of the N-terminal extension in Methanosarcina acetivorans protoglobin 448
Somatostatin Modulates Insulin-Degrading-Enzyme Metabolism: Implications for the Regulation of Microglia Activity in AD 444
Metal ions affect insulin-degrading enzyme activity 438
Evidence for pH-dependent multiple conformers in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding. 436
Evidence for pH-dependent multiple conformesrs in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding 419
Novel Platinum(II) compounds modulate insulin‑degrading enzyme activity and induce cell death in neuroblastoma cells. 412
Electrostatic Map of Proteasome α-Rings Encodes the Design of Allosteric Porphyrin-Based Inhibitors Able to Affect 20S Conformation by Cooperative Binding 408
Nitrosylation Mechanisms of Mycobacterium tuberculosis and Campylobacter jejuni Truncated Hemoglobins N, O, and P. 405
Ibuprofen and warfarin modulate allosterically ferrous human serum heme-albumin nitrosylation 403
Multiple functions of insulin-degrading enzyme: a metabolic crosslight? 305
Enzyme catalysis: the case of the prostate-specific antigen 301
Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin 281
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S 281
Effects of oral administration of common antioxidant supplements on the energy metabolism of red blood cells. Attenuation of oxidative stress-induced changes in Rett syndrome erythrocytes by CoQ10 249
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations 247
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome 245
null 243
Insulin-degrading enzyme (IDE): A novel heat shock-like protein 235
On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment 234
The proteasome as a druggable target with multiple therapeutic potentialities: cutting and non-cutting edges 233
The double faced role of copper in Aβ homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration 232
Functional and spectroscopic characterization of Chlamydomonas reinhardtii truncated hemoglobins 185
Insights into Proteasome Conformation Dynamics and Intersubunit Communication 179
Cationic porphyrins are tunable gatekeepers of the 20S proteasome 176
Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells 175
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo 173
Ferric nitrosylated myoglobin catalyzes peroxynitrite scavenging 166
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: novel insights into its pro-proteostatic effect 152
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways 149
Kinetics of cyanide and carbon monoxide dissociation from ferrous human haptoglobin:hemoglobin(II) complexes 140
Pyrazolones activate the proteasome by gating mechanisms and protect neuronal cells from β-amyloid toxicity 135
At the cutting edge against cancer: A perspective on immunoproteasome and immune checkpoints modulation as a potential therapeutic intervention 134
The nitrite reductase activity of ferrous human hemoglobin:haptoglobin 1-1 and 2-2 complexes 131
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects 128
A novel and atypical NF-KB pro-inflammatory program regulated by a CamKII-proteasome axis is involved in the early activation of Muller glia by high glucose 116
Author Correction: Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome (Scientific Reports, (2017), 7, 1, (12297), 10.1038/s41598-017-12069-0) 103
The interplay between lipid and Aβ amyloid homeostasis in Alzheimer's disease: risk factors and therapeutic opportunities 103
Insulin-degrading enzyme is a non proteasomal target of carfilzomib and affects the 20S proteasome inhibition by the drug 95
Dexamethasone downregulates autophagy through accelerated turn-over of the ulk-1 complex in a trabecular meshwork cells strain: Insights on steroid-induced glaucoma pathogenesis 84
High-glucose stimulation triggers early transcription of a panel of proinflammatory mediators in rat Muller glia cells and retina primary explants 78
Eye Diseases: When the Solution Comes from Plant Alkaloids 75
Corrigendum to “Silybins are stereospecific regulators of the 20S proteasome” [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813)) 73
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome 71
Modulation of the 20S proteasome activity by porphyrin derivatives is steered through their charge distribution 69
The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design 68
A Novel Lactobacillus brevis Fermented with a Vegetable Substrate (AL0035) Counteracts TNBS-Induced Colitis by Modulating the Gut Microbiota Composition and Intestinal Barrier 67
Silybins are stereospecific regulators of the 20S proteasome 67
Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches 66
Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects 62
Hydroxylamine-induced oxidation of ferrous nitrobindins 59
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells’ Ubiquitylome 58
Targeting immunoproteasome in neurodegeneration: a glance to the future 57
Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study 54
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome 52
Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics 41
The Interplay Between the Ubiquitin-Proteasome System and Oxidative Stress: A Future Perspective in Eye Diseases 30
SpectraSage unveils specific proteolytic patterns of 20S on mono-ubiquitylated Tau proteoforms involved in neurodegeneration 28
null 9
Totale 14.847
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Categoria #
all - tutte 39.782
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.782
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021175 0 0 0 0 0 0 0 0 0 78 69 28
2021/2022565 37 77 45 25 18 35 34 20 45 32 39 158
2022/2023576 55 49 16 74 57 120 60 49 43 8 35 10
2023/2024384 82 8 10 7 23 145 12 19 13 10 0 55
2024/20251.538 37 284 139 110 76 120 125 87 96 185 200 79
2025/20262.659 190 165 343 285 276 152 410 317 290 231 0 0
Totale 14.847