A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a milestone in our understanding of the structural dynamics of the 26S proteasome.

Tundo, G.r., Sbardella, D., Coletta, M. (2018). Insights into Proteasome Conformation Dynamics and Intersubunit Communication. TRENDS IN BIOCHEMICAL SCIENCES, 43(11), 852-853 [10.1016/j.tibs.2018.08.002].

Insights into Proteasome Conformation Dynamics and Intersubunit Communication

Tundo G. R.;Sbardella D.;Coletta M.
2018-01-01

Abstract

A recently published paper applies cryo-electron microscopy (EM) studies and biochemical/genetic approaches for the elucidation of the mechanisms linking nucleotide binding by ATPases, proteasome conformation dynamics, and gate opening of the 20S core particle. These insights potentially represent a milestone in our understanding of the structural dynamics of the 26S proteasome.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/10
English
Con Impact Factor ISI
ATPase cycle; allosteric interactions; conformation dynamics; core particles-regulatory particles interaction; proteasome assembly; Adenosine Triphosphatases; Molecular Conformation; Cryoelectron Microscopy; Proteasome Endopeptidase Complex
Tundo, G.r., Sbardella, D., Coletta, M. (2018). Insights into Proteasome Conformation Dynamics and Intersubunit Communication. TRENDS IN BIOCHEMICAL SCIENCES, 43(11), 852-853 [10.1016/j.tibs.2018.08.002].
Tundo, Gr; Sbardella, D; Coletta, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/229024
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