We explored the spatial distribution of human Y chromosomal diversity on a microgeographic scale, by typing 30 population samples from closely spaced locations in Italy and Greece for 9 haplogroups and their internal microsatellite variation. We confirm a significant difference in the composition of the Y chromosomal gene pools of the two countries. However, within each country, heterogeneity is not organized along the lines of clinal variation deduced from studies on larger spatial scales. Microsatellite data indicate that local increases of haplogroup frequencies can be often explained by a limited number of founders. We conclude that local founder or drift effects are the main determinants in shaping the microgeographic Y chromosomal diversity. (C) 2003 Elsevier Science (USA). All rights reserved.

Di Giacomo, F., Luca, F., Anagnou, N., Ciavarella, G., Corbo, R., Cresta, M., et al. (2003). Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects. In Molecular phylogenetics and evolution (pp.387-395). Elsevier [10.1016/S1055-7903(03)00016-2].

Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects

Luca, F;TERRENATO, LUCIANO;MALASPINA, PATRIZIA;NOVELLETTO, ANDREA
2003-01-01

Abstract

We explored the spatial distribution of human Y chromosomal diversity on a microgeographic scale, by typing 30 population samples from closely spaced locations in Italy and Greece for 9 haplogroups and their internal microsatellite variation. We confirm a significant difference in the composition of the Y chromosomal gene pools of the two countries. However, within each country, heterogeneity is not organized along the lines of clinal variation deduced from studies on larger spatial scales. Microsatellite data indicate that local increases of haplogroup frequencies can be often explained by a limited number of founders. We conclude that local founder or drift effects are the main determinants in shaping the microgeographic Y chromosomal diversity. (C) 2003 Elsevier Science (USA). All rights reserved.
Annual meeting of the Society for molecular biology and evolution
Sorrento
2002
Society for molecular biology and evolution
Rilevanza internazionale
contributo
2002
2003
Settore BIO/18 - GENETICA
English
microsatellite DNA; primer DNA; analysis of variance; comparative study; conference paper; founder effect; genetic drift; genetic variability; genetics; geography; Greece; haplotype; human; Italy; male; population dynamics; single nucleotide polymorphism; Y chromosome; Analysis of Variance; Chromosomes, Human, Y; DNA Primers; Founder Effect; Genetic Drift; Geography; Greece; haplotypes; microsatellite repeats; polymorphism, single nucleotide
Intervento a convegno
Di Giacomo, F., Luca, F., Anagnou, N., Ciavarella, G., Corbo, R., Cresta, M., et al. (2003). Clinal patterns of human Y chromosomal diversity in continental Italy and Greece are dominated by drift and founder effects. In Molecular phylogenetics and evolution (pp.387-395). Elsevier [10.1016/S1055-7903(03)00016-2].
Di Giacomo, F; Luca, F; Anagnou, N; Ciavarella, G; Corbo, R; Cresta, M; Cucci, F; Di Stasi, L; Agostiano, V; Giparaki, M; Loutradis, A; Mammì, C; Michalodimitrakis, E; Papola, F; Pedicini, G; Plata, E; Terrenato, L; Tofanelli, S; Malaspina, P; Novelletto, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/8734
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