OxLDL plays a major role in the initiation and progression of atherosclerotic lesions even though further factors are needed to promote fibrous cap rupture and thrombotic occlusion of the arterial lumen. Pathogens have been implicated in this process but it remains unclear how they can cooperate with oxLDL in amplifying the destructive inflammatory response.

Monteleone, I., Muscoli, S., Terribili, N., Zorzi, F., Mariano, E., Mehta, J., et al. (2013). Local immune activity in acute coronary syndrome: oxLDL abrogates LPS-tolerance in mononuclear cells isolated from culprit lesion. INTERNATIONAL JOURNAL OF CARDIOLOGY, 169(1), 44-51 [10.1016/j.ijcard.2013.08.082].

Local immune activity in acute coronary syndrome: oxLDL abrogates LPS-tolerance in mononuclear cells isolated from culprit lesion

MONTELEONE, IVAN;MUSCOLI, SAVERIO;TERRIBILI, NOEMI;PALLONE, FRANCESCO;MONTELEONE, GIOVANNI;ROMEO, FRANCESCO
2013-10-25

Abstract

OxLDL plays a major role in the initiation and progression of atherosclerotic lesions even though further factors are needed to promote fibrous cap rupture and thrombotic occlusion of the arterial lumen. Pathogens have been implicated in this process but it remains unclear how they can cooperate with oxLDL in amplifying the destructive inflammatory response.
25-ott-2013
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/12 - GASTROENTEROLOGIA
English
Con Impact Factor ISI
Atherosclerosis; Leukocytes, Mononuclear; LPS; Humans; Aged; TLR; Inflammation; T cell; Cells, Cultured; Acute Coronary Syndrome; Adult; Lipopolysaccharides; Middle Aged; Lipoproteins, LDL; oxLDL; Male; Female
Monteleone, I., Muscoli, S., Terribili, N., Zorzi, F., Mariano, E., Mehta, J., et al. (2013). Local immune activity in acute coronary syndrome: oxLDL abrogates LPS-tolerance in mononuclear cells isolated from culprit lesion. INTERNATIONAL JOURNAL OF CARDIOLOGY, 169(1), 44-51 [10.1016/j.ijcard.2013.08.082].
Monteleone, I; Muscoli, S; Terribili, N; Zorzi, F; Mariano, E; Mehta, J; Pallone, F; Monteleone, G; Romeo, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/86788
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