'Early onset sarcoidosis' is a chronic granulomatous disease occurring in children younger than 5 years of age, and characterized by a classic symptom triad consisting of skin, eye and joint lesions, with on rare occasion pulmonary involvement. The disorder often goes unrecognized because of its rarity and, since polyarthritis and uveitis are the predominant symptoms, most of these children are misdiagnosed as having juvenile chronic arthritis (JCA). A child with erythema nodosum at 7 months of age, later diagnosed as JCA and definitively recognized as 'early onset sarcoidosis' is reported. This case shows that, whenever possible, a biopsy showing the typical picture of sarcoid granulomas is crucial to distinguish these clinical conditions.

Cancrini, C., Angelini, F., Colavita, M., Cortis, E., Chini, L., Mammone, F., et al. (1998). Erythema nodosum: A presenting sign of early onset sarcoidosis. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 16(3), 337-339.

Erythema nodosum: A presenting sign of early onset sarcoidosis

CANCRINI, CATERINA;ANGELINI, FEDERICA;CHINI, LOREDANA;ROSSI, PAOLO;
1998-01-01

Abstract

'Early onset sarcoidosis' is a chronic granulomatous disease occurring in children younger than 5 years of age, and characterized by a classic symptom triad consisting of skin, eye and joint lesions, with on rare occasion pulmonary involvement. The disorder often goes unrecognized because of its rarity and, since polyarthritis and uveitis are the predominant symptoms, most of these children are misdiagnosed as having juvenile chronic arthritis (JCA). A child with erythema nodosum at 7 months of age, later diagnosed as JCA and definitively recognized as 'early onset sarcoidosis' is reported. This case shows that, whenever possible, a biopsy showing the typical picture of sarcoid granulomas is crucial to distinguish these clinical conditions.
1998
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
English
Early onset sarcoidosis; Erythema nodosum; Juvenile chronic arthritis; Uveitis
prednisone; article; case report; clinical feature; disease association; erythema nodosum; female; human; infant; onset age; polyarthritis; priority journal; sarcoidosis; uveitis; Age of Onset; Arthritis, Juvenile Rheumatoid; Child, Preschool; Diagnosis, Differential; Erythema Nodosum; Female; Humans; Infant; Sarcoidosis
Cancrini, C., Angelini, F., Colavita, M., Cortis, E., Chini, L., Mammone, F., et al. (1998). Erythema nodosum: A presenting sign of early onset sarcoidosis. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 16(3), 337-339.
Cancrini, C; Angelini, F; Colavita, M; Cortis, E; Chini, L; Mammone, F; Rossi, P; De Sanctis, R
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/57590
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