Hyperglycemia impairs functional properties of cytosolic and nuclear proteins via O-linked glycosylation modification (O-GlcNAcylation). We studied the effects of O-GlcNAcylation on insulin signaling in human coronary artery endothelial cells.
Federici, M., Menghini, R., Mauriello, A., Hribal, M., Ferrelli, F., Lauro, D., et al. (2002). Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells. CIRCULATION, 106(4), 466-472 [10.1161/01.CIR.0000023043.02648.51].
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells
FEDERICI, MASSIMO;MENGHINI, ROSSELLA;MAURIELLO, ALESSANDRO;LAURO, DAVIDE;SBRACCIA, PAOLO;SESTI, GIORGIO;LAURO, RENATO
2002-07-23
Abstract
Hyperglycemia impairs functional properties of cytosolic and nuclear proteins via O-linked glycosylation modification (O-GlcNAcylation). We studied the effects of O-GlcNAcylation on insulin signaling in human coronary artery endothelial cells.File in questo prodotto:
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