Hepatitis C-related cirrhosis is currently the most common cause of orthotopic liver transplantation worldwide. However, hepatitis C virus infection invariably recurs after liver transplantation. In recent years, it has become apparent that hepatitis C recurrence progresses more rapidly, and is less responsive to antiviral treatment, compared to pre-transplant infection. The present review addresses the natural history of hepatitis C recurrence in the liver transplant recipient, the factors implicated in its progression, and the rationale for prevention and antiviral treatment.
Piccolo, P., Di Paolo, D., Tisone, G., Angelico, M. (2002). Hepatitis C recurrence after orthotopic liver transplantation: A clinical review. GASTROENTEROLOGY INTERNATIONAL, 15, 24-31.
Hepatitis C recurrence after orthotopic liver transplantation: A clinical review
TISONE, GIUSEPPE;ANGELICO, MARIO
2002-01-01
Abstract
Hepatitis C-related cirrhosis is currently the most common cause of orthotopic liver transplantation worldwide. However, hepatitis C virus infection invariably recurs after liver transplantation. In recent years, it has become apparent that hepatitis C recurrence progresses more rapidly, and is less responsive to antiviral treatment, compared to pre-transplant infection. The present review addresses the natural history of hepatitis C recurrence in the liver transplant recipient, the factors implicated in its progression, and the rationale for prevention and antiviral treatment.Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons
