Magnesium-based bio-absorbable implants (MgBIs) are emerging as a promising alternative to conventional implants in current clinical practice. In this context, surgical planning and management could be significantly enhanced through advanced multiscale and multiphysics numerical models. As a first step in this direction, a phase-field approach is herein presented to model the degradation kinetics of MgBIs. The governing equations are consistently derived by minimizing the free energy, and are numerically solved using a finite-element formulation implemented with in-house codes. The model has been successfully validated by reproducing the dissolution of a cylindrical electrode in an electrolyte solution, and then applied to simulate the degradation of a magnesium-based screw. Available analytical results and experimental observations are well reproduced, highlighting the model’s soundness and effectiveness.

Gaziano, P., Zoboli, L., Marino, M., Gizzi, A., Vairo, G. (2025). Modeling the Degradation of Bio-absorbable Bone Implants: A Computational Approach. In Multiscale and Multiphysics Modelling for Advanced and Sustainable Materials (pp. 153-165). Springer [10.1007/978-3-031-84379-2_12].

Modeling the Degradation of Bio-absorbable Bone Implants: A Computational Approach

Gaziano, Pierfrancesco;Zoboli, Lorenzo;Marino, Michele;Vairo, Giuseppe
2025-01-01

Abstract

Magnesium-based bio-absorbable implants (MgBIs) are emerging as a promising alternative to conventional implants in current clinical practice. In this context, surgical planning and management could be significantly enhanced through advanced multiscale and multiphysics numerical models. As a first step in this direction, a phase-field approach is herein presented to model the degradation kinetics of MgBIs. The governing equations are consistently derived by minimizing the free energy, and are numerically solved using a finite-element formulation implemented with in-house codes. The model has been successfully validated by reproducing the dissolution of a cylindrical electrode in an electrolyte solution, and then applied to simulate the degradation of a magnesium-based screw. Available analytical results and experimental observations are well reproduced, highlighting the model’s soundness and effectiveness.
2025
Settore ICAR/08
Settore CEAR-06/A - Scienza delle costruzioni
English
Rilevanza internazionale
Capitolo o saggio
Bio-absorbable bone implants
Magnesium alloys degradation
Moving boundary problems
Phase-field approach
Gaziano, P., Zoboli, L., Marino, M., Gizzi, A., Vairo, G. (2025). Modeling the Degradation of Bio-absorbable Bone Implants: A Computational Approach. In Multiscale and Multiphysics Modelling for Advanced and Sustainable Materials (pp. 153-165). Springer [10.1007/978-3-031-84379-2_12].
Gaziano, P; Zoboli, L; Marino, M; Gizzi, A; Vairo, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/455828
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