background: availability of liver transplantation (LT) as a treatment for hepatocellular carcinoma (HCC) and other liver malignancies may determine heterogeneity of therapeutic strategies across different centers. aims: to investigate the practice between hepato-biliary centers without (HB centers) and with a LT program (LT centers), we launched a 38-item web-based national survey, with directors of centers as a target. methods: the survey, including 4 clinical vignettes, collected data on their approach to HCC and transplant oncology. results: after duplicates removal, 75 respondents were considered. Respondents from LT centers (n = 22, 29.3 %) were more in favor of LT in the case of HCC outside milan criteria (90.9 % vs. 67.9 %, p = 0.037), recurrent HCC (95.5 % vs. 50.9 %, p = 0.002) and other malignancies such as cholangiocarcinoma or neuroendocrine tumors. no significant difference was observed concerning the proportion of centers favorable to LT for unresectable colorectal liver metastases (100 % vs. 88.7 %, p = 0.100). conclusion: this national survey showed how management of HCC and awareness of transplant oncology may differ between HB and LT centers. effective networking between HB and LT centers is crucial to provide optimal treatment and access to LT.

Serenari, M., Angelico, R., Lai, Q., Patrono, D., Scalera, I., Kauffmann, E., et al. (2024). Current management of hepatobiliary malignancies between centers with or without a liver transplant program: A multi-society national survey. DIGESTIVE AND LIVER DISEASE [10.1016/j.dld.2024.09.007].

Current management of hepatobiliary malignancies between centers with or without a liver transplant program: A multi-society national survey

Angelico R.;Pagano D.;Antonucci A.;Carraro A.;Tisone G.;Morelli L.;Crespi M. A.;Troisi R.;Guerriero S.;
2024-01-01

Abstract

background: availability of liver transplantation (LT) as a treatment for hepatocellular carcinoma (HCC) and other liver malignancies may determine heterogeneity of therapeutic strategies across different centers. aims: to investigate the practice between hepato-biliary centers without (HB centers) and with a LT program (LT centers), we launched a 38-item web-based national survey, with directors of centers as a target. methods: the survey, including 4 clinical vignettes, collected data on their approach to HCC and transplant oncology. results: after duplicates removal, 75 respondents were considered. Respondents from LT centers (n = 22, 29.3 %) were more in favor of LT in the case of HCC outside milan criteria (90.9 % vs. 67.9 %, p = 0.037), recurrent HCC (95.5 % vs. 50.9 %, p = 0.002) and other malignancies such as cholangiocarcinoma or neuroendocrine tumors. no significant difference was observed concerning the proportion of centers favorable to LT for unresectable colorectal liver metastases (100 % vs. 88.7 %, p = 0.100). conclusion: this national survey showed how management of HCC and awareness of transplant oncology may differ between HB and LT centers. effective networking between HB and LT centers is crucial to provide optimal treatment and access to LT.
2024
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MEDS-06/A - Chirurgia generale
English
Hepatocellular carcinoma
Liver transplantation
Survey
Serenari, M., Angelico, R., Lai, Q., Patrono, D., Scalera, I., Kauffmann, E., et al. (2024). Current management of hepatobiliary malignancies between centers with or without a liver transplant program: A multi-society national survey. DIGESTIVE AND LIVER DISEASE [10.1016/j.dld.2024.09.007].
Serenari, M; Angelico, R; Lai, Q; Patrono, D; Scalera, I; Kauffmann, E; Pagano, D; De Carlis, R; Gringeri, E; Vitale, A; Antonucci, A; Brolese, A; Pat...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/388961
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