Deep Eutectic Solvents (DESs) offer advantages similar to ionic liquid (IL) ones, with easier and more sustainable synthesis; moreover, bio-based DESs often include chiral components, surprisingly underexploited. A proof of concept is now offered of the impressive potential of enantiopure chiral DESs as chiral media for enantioselective electroanalysis. Three chiral DESs, consisting of a molecular salt with bio-based chiral cation [NopolMIm]+ combined with three natural and/or low-cost partners (levulinic acid, glycerol and urea), are introduced and investigated as chiral voltammetry media. Significant potential differences are observed for the enantiomers of a model chiral probe, with a dramatic tuning depending on the achiral DES component, reaching an impressive~ 0.5 V in the levulinic acid case (while less efficient appears [NopolMIm]+ as chiral additive in IL). With the same medium good enantiodiscrimination is also observed for aminoacid tryptophan, a quite different probe and of applicative interest. These findings can be considered as a remarkable step further in chiral electroanalysis as well as in the development of task-specific enantioselective media.

Emanuele, E., Arnaboldi, S., Grecchi, S., Emanuele, E., Guazzelli, L., Longhi, M., et al. (2021). Deep eutectic solvents with bio-based chiral cations: a new electroanalytical approach for the enantiomeric excess determination of chiral probes. ??????? it.cilea.surplus.oa.citation.tipologie.CitationProceedings.prensentedAt ??????? Annual Meeting of the International Society of Electrochemistry (ISE 2020).

Deep eutectic solvents with bio-based chiral cations: a new electroanalytical approach for the enantiomeric excess determination of chiral probes

F Arduini;L Micheli;
2021-01-01

Abstract

Deep Eutectic Solvents (DESs) offer advantages similar to ionic liquid (IL) ones, with easier and more sustainable synthesis; moreover, bio-based DESs often include chiral components, surprisingly underexploited. A proof of concept is now offered of the impressive potential of enantiopure chiral DESs as chiral media for enantioselective electroanalysis. Three chiral DESs, consisting of a molecular salt with bio-based chiral cation [NopolMIm]+ combined with three natural and/or low-cost partners (levulinic acid, glycerol and urea), are introduced and investigated as chiral voltammetry media. Significant potential differences are observed for the enantiomers of a model chiral probe, with a dramatic tuning depending on the achiral DES component, reaching an impressive~ 0.5 V in the levulinic acid case (while less efficient appears [NopolMIm]+ as chiral additive in IL). With the same medium good enantiodiscrimination is also observed for aminoacid tryptophan, a quite different probe and of applicative interest. These findings can be considered as a remarkable step further in chiral electroanalysis as well as in the development of task-specific enantioselective media.
Annual Meeting of the International Society of Electrochemistry (ISE 2020)
2020
71.
Rilevanza internazionale
contributo
2021
Settore CHIM/01 - CHIMICA ANALITICA
Settore CHIM/02 - CHIMICA FISICA
English
Intervento a convegno
Emanuele, E., Arnaboldi, S., Grecchi, S., Emanuele, E., Guazzelli, L., Longhi, M., et al. (2021). Deep eutectic solvents with bio-based chiral cations: a new electroanalytical approach for the enantiomeric excess determination of chiral probes. ??????? it.cilea.surplus.oa.citation.tipologie.CitationProceedings.prensentedAt ??????? Annual Meeting of the International Society of Electrochemistry (ISE 2020).
Emanuele, E; Arnaboldi, S; Grecchi, S; Emanuele, E; Guazzelli, L; Longhi, M; Arduini, F; Micheli, L; Mussini, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/291422
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