Introducing the Iguana Genome Project

The Iguana Genome Project is currently conducted in the frame of the Consortium for Iguana Genome (CIG). The CIG is coordinated and led by the University Tor Vergata (Rome, Italy) and at present is in partnership with the Malaysia Genome Institute, the Universiti Kebangsaan Malaysia (UKM), and the University of Leeds (UK). The project aims to provide a genomic perspective on the origins, evolution, and adaptation of Galápagos Iguanas, taking advantage of latest advances in genomics and transcriptomics. Several questions will be tackled such as the adaptation to diving, the origin and implications of depigmentation, the genetic base of ecological requirements, and physiological and behavioral responses to the environment. Additionally, the project uses a genomic approach to reconstruct the most recent demographic history of specific populations and address the role of hybridization in guiding the evolutionary processes in Galápagos species. Finally, the project also aims to provide reference genomes for the conservation of threatened species. The CIG has already produced genome data of Conolophus marthae (93X coverage), Conolophus pallidus (10X coverage), and Amblyrhynchus cristatus (40 X coverage). Conolophus subcristatus’ genome is currently being sequenced. RNAs have been processed for transcriptome analysis for all Galápagos species. The project aims to carry out the investigations within a phylogenetic framework, and so the sequencing of the genomes of other genera of Iguanidae (Cyclura and Ctenosaura) is currently programmed. The long term objective is to extend the investigation to the whole family Iguanidae. For this reason, the participation of other partners is envisioned and welcome.