Medical advances have dramatically improved the long-term prognosis of children and adolescents with inborn errors of immunity (IEIs). Transfer of the medical care of individuals with pediatric IEIs to adult facilities is also a complex task because of the large number of distinct disorders, which requires involvement of patients and both pediatric and adult care providers. To date, there is no consensus on the optimal pathway of the transitional care process and no specific data are available in the literature regarding patients with IEIs. We aimed to develop a consensus statement on the transition process to adult health care services for patients with IEIs. Physicians from major Italian Primary Immunodeficiency Network centers formulated and answered questions after examining the currently published literature on the transition from childhood to adulthood. The authors voted on each recommendation. The most frequent IEIs sharing common main clinical problems requiring full attention during the transitional phase were categorized into different groups of clinically related disorders. For each group of clinically related disorders, physicians from major Italian Primary Immunodeficiency Network institutions focused on selected clinical issues representing the clinical hallmark during early adulthood.

Cirillo, E., Giardino, G., Ricci, S., Moschese, V., Lougaris, V., Conti, F., et al. (2020). Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity. THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 146(5), 967-983 [10.1016/j.jaci.2020.08.010].

Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity

Moschese, Viviana;Conti, Francesca;Barzaghi, Federica;Cancrini, Caterina;Finocchi, Andrea;Amodio, Donato;Aiuti, Alessandro;
2020-11-01

Abstract

Medical advances have dramatically improved the long-term prognosis of children and adolescents with inborn errors of immunity (IEIs). Transfer of the medical care of individuals with pediatric IEIs to adult facilities is also a complex task because of the large number of distinct disorders, which requires involvement of patients and both pediatric and adult care providers. To date, there is no consensus on the optimal pathway of the transitional care process and no specific data are available in the literature regarding patients with IEIs. We aimed to develop a consensus statement on the transition process to adult health care services for patients with IEIs. Physicians from major Italian Primary Immunodeficiency Network centers formulated and answered questions after examining the currently published literature on the transition from childhood to adulthood. The authors voted on each recommendation. The most frequent IEIs sharing common main clinical problems requiring full attention during the transitional phase were categorized into different groups of clinically related disorders. For each group of clinically related disorders, physicians from major Italian Primary Immunodeficiency Network institutions focused on selected clinical issues representing the clinical hallmark during early adulthood.
nov-2020
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
English
DNA repair syndromes
DiGeorge syndrome
Italian Network of Primary Immunodeficiencies
Transitional care
combined immunodeficiency
humoral immune defects
inborn errors of immunity
innate immune defects
primary immunodeficiency
Cirillo, E., Giardino, G., Ricci, S., Moschese, V., Lougaris, V., Conti, F., et al. (2020). Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity. THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 146(5), 967-983 [10.1016/j.jaci.2020.08.010].
Cirillo, E; Giardino, G; Ricci, S; Moschese, V; Lougaris, V; Conti, F; Azzari, C; Barzaghi, F; Canessa, C; Martire, B; Badolato, R; Dotta, L; Soresina, A; Cancrini, C; Finocchi, A; Montin, D; Romano, R; Amodio, D; Ferrua, F; Tommasini, A; Baselli, La; Dellepiane, Rm; Polizzi, A; Chessa, L; Marzollo, A; Cicalese, Mp; Putti, Mc; Pession, A; Aiuti, A; Locatelli, F; Plebani, A; Pignata, C
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/257986
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