In type 1 diabetes (T1D) vascular complications such as accelerated atherosclerosis and diffused macro-/microangiopathy are linked to chronic hyperglycemia with a mechanism that is not yet well understood. End-stage renal disease (ESRD) worsens most diabetic complications, particularly, the risk of morbidity and mortality from cardiovascular disease is increased several fold.

Folli, F., Guzzi, V., Perego, L., Coletta, D., Finzi, G., Placidi, C., et al. (2010). Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation. PLOS ONE, 5(3), e9923 [10.1371/journal.pone.0009923].

Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation

LAURO, DAVIDE;
2010-01-01

Abstract

In type 1 diabetes (T1D) vascular complications such as accelerated atherosclerosis and diffused macro-/microangiopathy are linked to chronic hyperglycemia with a mechanism that is not yet well understood. End-stage renal disease (ESRD) worsens most diabetic complications, particularly, the risk of morbidity and mortality from cardiovascular disease is increased several fold.
2010
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/50 - SCIENZE TECNICHE MEDICHE APPLICATE
English
Con Impact Factor ISI
Kidney Transplantation; Male; Pancreas Transplantation; Proteomics; Middle Aged; Diabetes Mellitus, Type 1; Female; Kidney Failure, Chronic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Skin; Humans; Oxygen; Gene Expression Regulation; Glycolysis; Adult; Case-Control Studies
Folli, F., Guzzi, V., Perego, L., Coletta, D., Finzi, G., Placidi, C., et al. (2010). Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation. PLOS ONE, 5(3), e9923 [10.1371/journal.pone.0009923].
Folli, F; Guzzi, V; Perego, L; Coletta, D; Finzi, G; Placidi, C; La Rosa, S; Capella, C; Socci, C; Lauro, D; Tripathy, D; Jenkinson, C; Paroni, R; Ors...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/24907
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