Renal transplantation has become a well-established therapeutic option for end-stage renal disease, but infectious diseases remain a significant cause of morbidity and mortality. Although a wide variety of pathogens may cause infection, viral ones must be regarded as the single most important class of infections. Progress has been made both in the prevention and the early recognition treatment of infections that are closely linked to rejection. Immunosuppressive therapy is central to the pathogenesis of both. Because of the particular characteristics of transplant recipients, it is desirable to establish a close collaboration between nephrologists, surgeons, and infectious disease specialists for the management of these patients. In this article, we describe the different kinds of infectious disease that may affect patients with kidney transplant and the fundamental principles of clinical management, particularly our experience in Polyoma virus (BK) infection.
Splendiani, G., Cipriani, S., Tisone, G., Iorio, B., Condo, S., Vega, A., et al. (2005). Infectious complications in renal transplant recipients. TRANSPLANTATION PROCEEDINGS, 37(6), 2497-2499 [10.1016/j.transproceed.2005.06.012].
Infectious complications in renal transplant recipients
SPLENDIANI, GIORGIO;TISONE, GIUSEPPE;IORIO, BENIAMINO;CASCIANI, CARLO UMBERTO
2005-01-01
Abstract
Renal transplantation has become a well-established therapeutic option for end-stage renal disease, but infectious diseases remain a significant cause of morbidity and mortality. Although a wide variety of pathogens may cause infection, viral ones must be regarded as the single most important class of infections. Progress has been made both in the prevention and the early recognition treatment of infections that are closely linked to rejection. Immunosuppressive therapy is central to the pathogenesis of both. Because of the particular characteristics of transplant recipients, it is desirable to establish a close collaboration between nephrologists, surgeons, and infectious disease specialists for the management of these patients. In this article, we describe the different kinds of infectious disease that may affect patients with kidney transplant and the fundamental principles of clinical management, particularly our experience in Polyoma virus (BK) infection.Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons