Mesalamine has been reported to protect against inflammatory bowel disease-related colorectal cancer (CRC), but several drug-related issues have limited its use in chemopreventive programs. We evaluated the antineoplastic properties of mesalamine derivatives using in vitro and in vivo models of CRC.
Stolfi, C., Sarra, M., Caruso, R., Fantini, M.c., Fina, D., Pellegrini, R., et al. (2010). Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine. GASTROENTEROLOGY, 138(1), 221-230 [10.1053/j.gastro.2009.08.062].
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine
Stolfi, C;FANTINI, MASSIMO CLAUDIO;PALMIERI, GIAMPIERO;PALLONE, FRANCESCO;MONTELEONE, GIOVANNI
2010-01-01
Abstract
Mesalamine has been reported to protect against inflammatory bowel disease-related colorectal cancer (CRC), but several drug-related issues have limited its use in chemopreventive programs. We evaluated the antineoplastic properties of mesalamine derivatives using in vitro and in vivo models of CRC.File in questo prodotto:
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