The neurologic sequelae post-measles are less common than other complications measles-related and can lead to severe disability or death: primary measles encephalitis (PME), acute post-infectious measles encephalomyelitis (APME), measles inclusion body encephalitis (MIBE), and subacute sclerosing panencephalitis (SSPE). SSPE syndrome can affect people years from the acute measles virus infection, as result of the persistence of defective viral particles in brain cells. Clinical onset typically manifests with progressive intellectual deterioration, behavioral changes, and myoclonic jerks. The course of SSPE in the majority of affected children is that of a progressive worsening with fatal outcome within two years. This report described an Italian case of fulminant SSPE syndrome that led to death within few months from the initial onset.

Magurano, F., Marella, G.l., Marchi, A., Filia, A., Marsella, L.t., Potenza, S., et al. (2017). A case of fulminant subacute sclerosing panencephalitis presenting with acute myoclonic-astatic epilepsy. ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ, 53(2), 167-169 [10.4415/ANN_17_02_15].

A case of fulminant subacute sclerosing panencephalitis presenting with acute myoclonic-astatic epilepsy

Marella G. L.;Filia A.;Marsella L. T.;Potenza S.;Massa R.;
2017

Abstract

The neurologic sequelae post-measles are less common than other complications measles-related and can lead to severe disability or death: primary measles encephalitis (PME), acute post-infectious measles encephalomyelitis (APME), measles inclusion body encephalitis (MIBE), and subacute sclerosing panencephalitis (SSPE). SSPE syndrome can affect people years from the acute measles virus infection, as result of the persistence of defective viral particles in brain cells. Clinical onset typically manifests with progressive intellectual deterioration, behavioral changes, and myoclonic jerks. The course of SSPE in the majority of affected children is that of a progressive worsening with fatal outcome within two years. This report described an Italian case of fulminant SSPE syndrome that led to death within few months from the initial onset.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/43 - Medicina Legale
English
Child, Preschool; Diagnosis, Differential; Epilepsies, Myoclonic; Fatal Outcome; Female; Humans; Magnetic Resonance Imaging; Subacute Sclerosing Panencephalitis
Magurano, F., Marella, G.l., Marchi, A., Filia, A., Marsella, L.t., Potenza, S., et al. (2017). A case of fulminant subacute sclerosing panencephalitis presenting with acute myoclonic-astatic epilepsy. ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ, 53(2), 167-169 [10.4415/ANN_17_02_15].
Magurano, F; Marella, Gl; Marchi, A; Filia, A; Marsella, Lt; Potenza, S; Massa, R; Bucci, P; Baggieri, M; Nicoletti, L
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/209250
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