Objectives: Red blood cell distribution width (RDW) is a numerical measure of the variability in size of circulating erythrocytes and is emerging as a strong predictor of adverse advents for several categories of patients affected by cardiovascular disease. However, no data exist until now about the role of RDW in predicting mortality of aortic valve replacement (AVR) patients. Thus, in this pilot study we evaluated the value of RDW on early outcome following AVR. Methods: We enrolled 75 patients, who underwent AVR with or without concomitant procedure. A high value of RDW was defined as >43 fL for women and 47 fL for men. Multivariable and univariable analysis were used in determining the association between preoperative high RDW and postoperative outcome. Results: The prevalence of preoperative high RDW was 41% (31 patients). Univariable analysis showed that patients with high RDW were older (P < 0.02), with low weight (P = 0.12) and high level of platelets (P = 0.005). Patients with high RDW were more likely to require renal replacement therapy (P < 0.026) and prolonged ventilation (P < 0.01). Following multivariable adjustment, higher preoperative RDW was a combined predictor of mortality with higher creatinine level (P = 0.065). Conclusion: Increased RDW seems to be a good predictor of early outcome in patients who underwent AVR, in particular in patients with preoperative renal impairment and postoperative prolonged ventilation

Pisano, C., Balistreri, C.r., Merlo, D., Argano, V., Triolo, O.f., Palmeri, C., et al. (2014). 185 * RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT. ??????? it.cilea.surplus.oa.citation.tipologie.CitationProceedings.prensentedAt ??????? 28th EACTS Annual Meeting, Milano [10.1093/icvts/ivu276.185].

185 * RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT

Pisano, C.
Writing – Original Draft Preparation
;
Ruvolo, G.
Writing – Review & Editing
2014-10

Abstract

Objectives: Red blood cell distribution width (RDW) is a numerical measure of the variability in size of circulating erythrocytes and is emerging as a strong predictor of adverse advents for several categories of patients affected by cardiovascular disease. However, no data exist until now about the role of RDW in predicting mortality of aortic valve replacement (AVR) patients. Thus, in this pilot study we evaluated the value of RDW on early outcome following AVR. Methods: We enrolled 75 patients, who underwent AVR with or without concomitant procedure. A high value of RDW was defined as >43 fL for women and 47 fL for men. Multivariable and univariable analysis were used in determining the association between preoperative high RDW and postoperative outcome. Results: The prevalence of preoperative high RDW was 41% (31 patients). Univariable analysis showed that patients with high RDW were older (P < 0.02), with low weight (P = 0.12) and high level of platelets (P = 0.005). Patients with high RDW were more likely to require renal replacement therapy (P < 0.026) and prolonged ventilation (P < 0.01). Following multivariable adjustment, higher preoperative RDW was a combined predictor of mortality with higher creatinine level (P = 0.065). Conclusion: Increased RDW seems to be a good predictor of early outcome in patients who underwent AVR, in particular in patients with preoperative renal impairment and postoperative prolonged ventilation
28th EACTS Annual Meeting
Milano
2014
Rilevanza internazionale
ott-2014
Settore MED/23 - Chirurgia Cardiaca
English
cardiovascular disease, red distribution width, aortic valve replacement, prolonged ventilation, renal failure
Intervento a convegno
Pisano, C., Balistreri, C.r., Merlo, D., Argano, V., Triolo, O.f., Palmeri, C., et al. (2014). 185 * RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT. ??????? it.cilea.surplus.oa.citation.tipologie.CitationProceedings.prensentedAt ??????? 28th EACTS Annual Meeting, Milano [10.1093/icvts/ivu276.185].
Pisano, C; Balistreri, Cr; Merlo, D; Argano, V; Triolo, Of; Palmeri, C; Tulumello, E; Ruvolo, G
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/192486
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