In industrialized countries, overweight and obesity account for approximately 13.8% and 24.9% of the kidney disease observed in men and women, respectively. Moreover, obesity-associated glomerulopathy is now considered as "an emerging epidemic." Kidney function can be negatively impacted by obesity through several mechanisms, either direct or indirect. While it is well established that obesity represents the leading risk factor for type 2 diabetes and hypertension, awareness that obesity is associated with direct kidney damage independently of hypertension and diabetes is still not widespread. In this paper we will discuss the emerging role of adipose tissue, particularly in the visceral depot, in obesity-induced chronic kidney damage.

Mascali, A., Franzese, O., Nistico', S.p., Campia, U., Lauro, D., Cardillo, C., et al. (2016). Obesity and kidney disease: Beyond the hyperfiltration. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY [10.1177/0394632016643550].

Obesity and kidney disease: Beyond the hyperfiltration

MASCALI, ALBERTO;FRANZESE, ORNELLA;NISTICO', STEVEN PAUL;LAURO, DAVIDE;DI DANIELE, NICOLA;TESAURO, MANFREDI
2016-04-04

Abstract

In industrialized countries, overweight and obesity account for approximately 13.8% and 24.9% of the kidney disease observed in men and women, respectively. Moreover, obesity-associated glomerulopathy is now considered as "an emerging epidemic." Kidney function can be negatively impacted by obesity through several mechanisms, either direct or indirect. While it is well established that obesity represents the leading risk factor for type 2 diabetes and hypertension, awareness that obesity is associated with direct kidney damage independently of hypertension and diabetes is still not widespread. In this paper we will discuss the emerging role of adipose tissue, particularly in the visceral depot, in obesity-induced chronic kidney damage.
4-apr-2016
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/09 - MEDICINA INTERNA
Settore MED/13 - ENDOCRINOLOGIA
English
Con Impact Factor ISI
hyperfiltration; kidney disease; obesity
Mascali, A., Franzese, O., Nistico', S.p., Campia, U., Lauro, D., Cardillo, C., et al. (2016). Obesity and kidney disease: Beyond the hyperfiltration. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY [10.1177/0394632016643550].
Mascali, A; Franzese, O; Nistico', Sp; Campia, U; Lauro, D; Cardillo, C; DI DANIELE, N; Tesauro, M
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/157289
Citazioni
  • ???jsp.display-item.citation.pmc??? 12
  • Scopus 23
  • ???jsp.display-item.citation.isi??? 21
social impact