The most common cause of end stage renal disease is diabetic nephropathy. An early diagnosis may allow an intervention to slow down disease progression. Recently, it has been hypothesized that glutathione-S-transferase (GST) activity may be a marker of severity of chronic kidney disease. In particular, a lower GST activity is present in healthy subjects compared to patients with nephropathy. In the present review we illustrate the scientific evidence underlying the possible role of GST activity in the development of diabetic nephropathy and we analyze its usefulness as a possible early biomarker of this diabetic complication.
Tesauro, M., Nisticò, S.P., Noce, A., Tarantino, A., Marrone, G., Costa, A., et al. (2015). The possible role of glutathione-S-transferase activity in diabetic nephropathy. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 28(1), 129-133 [10.1177/0394632015572564].
Tipologia: | Articolo su rivista | |
Citazione: | Tesauro, M., Nisticò, S.P., Noce, A., Tarantino, A., Marrone, G., Costa, A., et al. (2015). The possible role of glutathione-S-transferase activity in diabetic nephropathy. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 28(1), 129-133 [10.1177/0394632015572564]. | |
Lingua: | English | |
Settore Scientifico Disciplinare: | Settore MED/09 - Medicina Interna Settore MED/13 - Endocrinologia | |
Revisione (peer review): | Esperti anonimi | |
Tipo: | Articolo | |
Rilevanza: | Rilevanza internazionale | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1177/0394632015572564 | |
Stato di pubblicazione: | Pubblicato | |
Data di pubblicazione: | mar-2015 | |
Titolo: | The possible role of glutathione-S-transferase activity in diabetic nephropathy | |
Autori: | ||
Autori: | Tesauro, M; Nisticò, SP; Noce, A; Tarantino, A; Marrone, G; Costa, A; Rovella, V; Di Cola, G; Campia, U; Lauro, D; Cardillo, C; Di Daniele, N | |
Appare nelle tipologie: | 01 - Articolo su rivista |