| Nome |
# |
|
Aducanumab for Alzheimer’s disease: a regulatory perspective, file e291c0d9-21de-cddb-e053-3a05fe0aa144
|
899
|
|
Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology, file e291c0d7-e775-cddb-e053-3a05fe0aa144
|
473
|
|
Targeting SUMO-1ylation Contrasts Synaptic Dysfunction in a Mouse Model of Alzheimer's Disease, file e291c0d8-13f5-cddb-e053-3a05fe0aa144
|
358
|
|
Advances in the therapy of Alzheimer's disease: Targeting amyloid beta and tau and perspectives for the future, file e291c0d6-ceb6-cddb-e053-3a05fe0aa144
|
252
|
|
ACET is a highly potent and specific kainate receptor antagonist: Characterisation and effects on hippocampal mossy fibre function, file e291c0d7-b2d1-cddb-e053-3a05fe0aa144
|
251
|
|
Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia, file e291c0d7-b814-cddb-e053-3a05fe0aa144
|
233
|
|
RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis, file e291c0d6-0dfe-cddb-e053-3a05fe0aa144
|
197
|
|
Synaptoimmunology - roles in health and disease, file e291c0d6-bf82-cddb-e053-3a05fe0aa144
|
192
|
|
Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis, file e291c0d6-088e-cddb-e053-3a05fe0aa144
|
191
|
|
Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity, file e291c0d6-0379-cddb-e053-3a05fe0aa144
|
182
|
|
Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia., file e291c0d6-0618-cddb-e053-3a05fe0aa144
|
182
|
|
NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease., file e291c0d6-0d5a-cddb-e053-3a05fe0aa144
|
178
|
|
Unbalance between Excitation and Inhibition in Phenylketonuria, a Genetic Metabolic Disease Associated with Autism, file e291c0d6-b43c-cddb-e053-3a05fe0aa144
|
177
|
|
Ginkgolic Acid Protects against Aβ-Induced Synaptic Dysfunction in the Hippocampus, file e291c0d6-b2e0-cddb-e053-3a05fe0aa144
|
174
|
|
Profile of gantenerumab and its potential in the treatment of Alzheimer's disease, file e291c0d7-ed3a-cddb-e053-3a05fe0aa144
|
162
|
|
Synaptic plasticity in multiple sclerosis and in experimental autoimmune encephalomyelitis, file e291c0d7-bec8-cddb-e053-3a05fe0aa144
|
160
|
|
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system, file e291c0d7-fd06-cddb-e053-3a05fe0aa144
|
154
|
|
The β-secretase BACE1 in Alzheimer's disease, file e291c0d8-7122-cddb-e053-3a05fe0aa144
|
146
|
|
Nonclinical data supporting orphan medicinal product designations in the area of rare infectious diseases, file e291c0d7-9c3a-cddb-e053-3a05fe0aa144
|
144
|
|
Inhibition of hippocampal plasticity in rats performing contrafreeloading for
water under repeated administrations of pramipexole, file e291c0d6-02c3-cddb-e053-3a05fe0aa144
|
143
|
|
Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine, file e291c0d6-d1c0-cddb-e053-3a05fe0aa144
|
142
|
|
The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic, file e291c0d6-bad7-cddb-e053-3a05fe0aa144
|
136
|
|
Cerebrospinal Fluid Neurogranin as a Biomarker of Neurodegenerative Diseases: A Cross-Sectional Study, file e291c0d6-ca41-cddb-e053-3a05fe0aa144
|
135
|
|
PDGF Modulates Synaptic Excitability and Short-Latency Afferent Inhibition in Multiple Sclerosis, file e291c0d6-d91a-cddb-e053-3a05fe0aa144
|
135
|
|
Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus, file e291c0d6-c174-cddb-e053-3a05fe0aa144
|
127
|
|
A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease, file e291c0d8-52e9-cddb-e053-3a05fe0aa144
|
122
|
|
Targeting Synaptic Plasticity in Experimental Models of Alzheimer's Disease, file e291c0d7-bd54-cddb-e053-3a05fe0aa144
|
116
|
|
A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus, file e291c0d8-2963-cddb-e053-3a05fe0aa144
|
115
|
|
ProNGFNGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice, file e291c0d7-ad5f-cddb-e053-3a05fe0aa144
|
114
|
|
Subtle alterations of excitatory transmission are linked to presynaptic changes in the hippocampus of PINK1-deficient mice, file e291c0d6-c20b-cddb-e053-3a05fe0aa144
|
105
|
|
The Golden Gate for Detection, Treatment and Prevention of Alzheimer's Disease, file e291c0d6-bad9-cddb-e053-3a05fe0aa144
|
103
|
|
Neuroprotective effect of hydrogen peroxide on an in vitro model of brain ischaemia, file e291c0d8-65a3-cddb-e053-3a05fe0aa144
|
101
|
|
Reply to the article "Management of status epilepticus in adults. Position paper of the Italian League against Epilepsy", file e291c0d7-ff6d-cddb-e053-3a05fe0aa144
|
99
|
|
Reply to the reply of the authors of the review article entitled "Management of status epilepticus in adults. Position paper of the Italian League against Epilepsy", file e291c0d8-a566-cddb-e053-3a05fe0aa144
|
94
|
|
Paradoxical abatement of striatal dopaminergic transmission by cocaine and methylphenidate, file e291c0d5-6019-cddb-e053-3a05fe0aa144
|
92
|
|
Acid-Sensing Ion Channel 1a Is Involved in N-Methyl D-Aspartate Receptor-Dependent Long-Term Depression in the Hippocampus, file e291c0d7-e59f-cddb-e053-3a05fe0aa144
|
87
|
|
Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals, file e291c0d8-062f-cddb-e053-3a05fe0aa144
|
84
|
|
Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats, file e291c0d7-77dc-cddb-e053-3a05fe0aa144
|
83
|
|
Excitotoxic mechanisms of apoptosis in the mammalian visual system following monocular visual deprivation, file e291c0d6-c209-cddb-e053-3a05fe0aa144
|
80
|
|
HIV-1 coat glycoprotein gp120 induces apoptosis in rat brain neocortex by deranging the arachidonate cascade in favor of prostanoids, file e291c0d8-6ff8-cddb-e053-3a05fe0aa144
|
80
|
|
The selective disruption of presynaptic JNK2/STX1a interaction reduces NMDA receptor-dependent glutamate release, file e291c0d7-fedb-cddb-e053-3a05fe0aa144
|
77
|
|
Exploitation of the HIV-1 coat glycoprotein, gp120, in neurodegenerative studies in vivo, file e291c0d8-5522-cddb-e053-3a05fe0aa144
|
77
|
|
Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome, file e291c0d7-bce1-cddb-e053-3a05fe0aa144
|
76
|
|
Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity, file e291c0d7-e77c-cddb-e053-3a05fe0aa144
|
75
|
|
Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria, file e291c0d7-e525-cddb-e053-3a05fe0aa144
|
73
|
|
Synergistic interactions between kainate and mGlu receptors regulate bouton Ca 2+ signalling and mossy fibre LTP, file e291c0d7-b780-cddb-e053-3a05fe0aa144
|
72
|
|
Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy, file e291c0d7-b41b-cddb-e053-3a05fe0aa144
|
70
|
|
Synaptic Plasticity and PDGF Signaling Defects Underlie Clinical Progression in Multiple Sclerosis, file e291c0d5-2a13-cddb-e053-3a05fe0aa144
|
69
|
|
Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release, file e291c0d7-d4a8-cddb-e053-3a05fe0aa144
|
67
|
|
Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion, file e291c0d7-ee8f-cddb-e053-3a05fe0aa144
|
66
|
|
The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils, file e291c0d8-63ce-cddb-e053-3a05fe0aa144
|
59
|
|
Oxidative stress in stroke pathophysiology validation of hydrogen peroxide metabolism as a pharmacological target to afford neuroprotection, file e291c0d6-cc4b-cddb-e053-3a05fe0aa144
|
46
|
|
The HIV-1 envelope protein, gp120, causes neuronal apoptosis in the neocortex of the adult rat: a useful experimental model to study neuroaids, file e291c0d6-cda7-cddb-e053-3a05fe0aa144
|
41
|
|
Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease, file e291c0d7-e705-cddb-e053-3a05fe0aa144
|
34
|
|
Acid-sensing ion channel 1a: a novel target in Alzheimer's disease?, file b1c8bd24-473d-4f82-b70a-3be971cf38c3
|
32
|
|
Evidence that increases of mitochondrial immunoreactive IL-1beta by HIV-1 gp120 implicate in situ cleavage of pro-IL-1beta in the neocortex of rat, file e291c0d8-5528-cddb-e053-3a05fe0aa144
|
21
|
|
Precision medicine and drug development in Alzheimer's disease: the importance of sexual dimorphism and patient stratification, file e291c0d7-e52c-cddb-e053-3a05fe0aa144
|
16
|
|
Early alteration of distribution and activity of hippocampal type-1 cannabinoid receptor in Alzheimer's disease-like mice overexpressing the human mutant amyloid precursor protein, file e291c0d7-f158-cddb-e053-3a05fe0aa144
|
16
|
|
Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins, file e291c0d7-b58a-cddb-e053-3a05fe0aa144
|
13
|
|
Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease, file e291c0d7-bcdf-cddb-e053-3a05fe0aa144
|
13
|
|
Alzheimer's disease: understanding homeostasis deregulation to foster development of effective therapies, file e291c0d7-e772-cddb-e053-3a05fe0aa144
|
13
|
|
The positive allosteric modulator at mGlu2 receptors, LY487379, reverses the effects of chronic stress-induced behavioral maladaptation and synaptic dysfunction in the adulthood, file e291c0d7-f59d-cddb-e053-3a05fe0aa144
|
13
|
|
Exploiting Focused Ultrasound to Aid Intranasal Drug Delivery for Brain Therapy, file 8f8986a7-ef5f-48d7-b779-29aee7f1d6ec
|
12
|
|
Defining Satisfactory Methods of Treatment in Rare Diseases When Evaluating Significant Benefit-The EU Regulator's Perspective, file 33ea4c9a-0a5d-41f3-ba9a-6ffc03c0a782
|
10
|
|
Involvement of Bradykinin Receptor 2 in Nerve Growth Factor Neuroprotective Activity, file 7dc3c30b-28f5-483f-b1ff-7bcb2ffdda46
|
10
|
|
Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740, file e291c0d7-b581-cddb-e053-3a05fe0aa144
|
10
|
|
Bromelain degrades Aβ1-42 monomers and soluble aggregates: an in vitro study in cerebrospinal fluid of Alzheimer's disease patients, file e291c0d7-e52f-cddb-e053-3a05fe0aa144
|
10
|
|
AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy, file e291c0d7-e532-cddb-e053-3a05fe0aa144
|
10
|
|
Interleukin-1β Promotes Long-Term Potentiation in Patients with Multiple Sclerosis, file e291c0d7-a79f-cddb-e053-3a05fe0aa144
|
9
|
|
Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions, file e291c0d7-b588-cddb-e053-3a05fe0aa144
|
9
|
|
Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: A long-range point of view beyond 2020, file e291c0d7-bced-cddb-e053-3a05fe0aa144
|
9
|
|
Genders and the concurrent use of cocaine and alcohol: Pharmacological aspects, file e291c0d8-0b9e-cddb-e053-3a05fe0aa144
|
9
|
|
Growth factors and synaptic plasticity in relapsing-remitting multiple sclerosis, file e291c0d7-a79d-cddb-e053-3a05fe0aa144
|
8
|
|
Unlocking the secrets of dopamine in Alzheimer's Disease, file e291c0d7-da98-cddb-e053-3a05fe0aa144
|
8
|
|
Role of ASIC1a in Aβ-induced synaptic alterations in the hippocampus, file e291c0d7-da9d-cddb-e053-3a05fe0aa144
|
8
|
|
Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory, file e291c0d7-f155-cddb-e053-3a05fe0aa144
|
8
|
|
D-Aspartate oxidase influences glutamatergic system homeostasis in mammalian brain, file e291c0d8-0da8-cddb-e053-3a05fe0aa144
|
8
|
|
Physical Exercise and Alzheimer's Disease: Effects on Pathophysiological Molecular Pathways of the Disease, file f1435b6f-a336-44a7-895c-99ce04074189
|
8
|
|
Neurodegenerative Disease: What Potential Therapeutic Role of Acid-Sensing Ion Channels?, file 12de45be-1fab-4924-b81a-6989503d772b
|
7
|
|
Optimising bench science to withstand regulatory scrutiny, file e291c0d7-f599-cddb-e053-3a05fe0aa144
|
7
|
|
N-ethyl lidocaine (QX-314) protects striatal neurons against ischemia: an in vitro electrophysiological study, file e291c0d7-fb4f-cddb-e053-3a05fe0aa144
|
7
|
|
Investigational treatments for neurodegenerative diseases caused by inheritance of gene mutations: lessons from recent clinical trials, file fd6fb6e9-7857-4b39-910f-8bf1dcfb74f8
|
7
|
|
SUMO: A (Oxidative) Stressed Protein, file e291c0d7-b67d-cddb-e053-3a05fe0aa144
|
6
|
|
The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus, file e291c0d7-ddfb-cddb-e053-3a05fe0aa144
|
6
|
|
Electrophysiological and metabolic effects of CHF5074 in the hippocampus: protection against in vitro ischemia, file e291c0d8-0006-cddb-e053-3a05fe0aa144
|
6
|
|
5-HT2C serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice, file e291c0d8-0daa-cddb-e053-3a05fe0aa144
|
6
|
|
Targeting Microglia-Synapse Interactions in Alzheimer's Disease, file 784d35d0-8765-4828-aa5e-0a36e2d84fa8
|
5
|
|
Reversal of metabolic and neurological symptoms of phenylketonuric mice treated with a PAH containing helper-dependent adenoviral vector, file e291c0d7-f8c9-cddb-e053-3a05fe0aa144
|
5
|
|
Effects of physical activity and exercise interventions on Alzheimer's disease: an umbrella review of existing meta-analyses, file 2614bd5d-0241-467e-8754-6cf65ffb6731
|
4
|
|
An exploratory study of the impact of COVID-19 vaccine spontaneous reporting on masking signal detection in EudraVigilance, file c3b492d5-7b12-4a82-b8a2-45da3fdf3113
|
4
|
|
Na+-Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory, file e291c0d7-abfa-cddb-e053-3a05fe0aa144
|
4
|
|
Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease, file e291c0d7-d518-cddb-e053-3a05fe0aa144
|
4
|
|
Synaptic plasticity as a therapeutic target in the treatment of autism-related single-gene disorders, file e291c0d7-d791-cddb-e053-3a05fe0aa144
|
4
|
|
L-DOPA: a scapegoat for accelerated neurodegeneration in Parkinson's disease?, file e291c0d7-e61a-cddb-e053-3a05fe0aa144
|
4
|
|
Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR, file e291c0d7-f660-cddb-e053-3a05fe0aa144
|
4
|
|
Cognitive impairment and dentate gyrus synaptic dysfunction in experimental parkinsonism, file e291c0d7-ffea-cddb-e053-3a05fe0aa144
|
4
|
|
Editorial: Neurotrophins Biodelivery to CNS: Innovative Approaches for Disease-Modifying Therapy, file 620a3f16-2460-45ea-9879-70a17dd2d38d
|
3
|
|
Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice, file e291c0d5-6a28-cddb-e053-3a05fe0aa144
|
3
|
|
Insulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory, file e291c0d7-a16a-cddb-e053-3a05fe0aa144
|
3
|
|
Integrating molecular mechanisms with synaptic plasticity in neurological disease, file e291c0d7-a16d-cddb-e053-3a05fe0aa144
|
3
|
| Totale |
8.289 |