| Nome |
# |
|
The peculiar heme pocket of the 2/2 hemoglobin of cold-adapted Pseudoalteromonas haloplanktis TAC125, file e291c0d3-e92e-cddb-e053-3a05fe0aa144
|
2.171
|
|
A rapid spectroscopic method to detect the fraudulent treatment of tuna fish with carbon monoxide, file e291c0d3-ef0d-cddb-e053-3a05fe0aa144
|
1.249
|
|
Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials, file e291c0d3-ef10-cddb-e053-3a05fe0aa144
|
1.041
|
|
Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes, file e291c0d4-4ea2-cddb-e053-3a05fe0aa144
|
952
|
|
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: Design, synthesis, and biological and structure-activity relationship studies, file e291c0d4-4fee-cddb-e053-3a05fe0aa144
|
791
|
|
Reversible two-step unfolding of heme-human serum albumin: A 1H-NMR relaxometric and circular dichroism study, file e291c0d3-ef06-cddb-e053-3a05fe0aa144
|
765
|
|
Cooperativity and allostery in haemoglobin function., file e291c0d4-4fa5-cddb-e053-3a05fe0aa144
|
745
|
|
HisE11 and HisF8 Provide Bis-histidyl Heme Hexa-coordination in the Globin Domain of Geobacter sulfurreducens Globin-coupled Sensor, file e291c0d3-ecd4-cddb-e053-3a05fe0aa144
|
660
|
|
Effects of a natural extract from Mangifera indica L, and its active compound, mangiferin, on energy state and lipid peroxidation of red blood cells, file e291c0d3-eeb2-cddb-e053-3a05fe0aa144
|
629
|
|
Extended cardiolipin anchorage to cytochrome c: model for protein-mitochondrial membrane binding., file e291c0d4-639c-cddb-e053-3a05fe0aa144
|
580
|
|
Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity, file e291c0d3-ef14-cddb-e053-3a05fe0aa144
|
553
|
|
Role of metalloproteinases in tendon pathophysiology., file e291c0d5-bf77-cddb-e053-3a05fe0aa144
|
542
|
|
Pseudo-enzymatic hydrolysis of 4-nitrophenyl acetate by human serum albumin: pH-dependence of rates of individual steps., file e291c0d4-8053-cddb-e053-3a05fe0aa144
|
518
|
|
Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory, file e291c0d4-530a-cddb-e053-3a05fe0aa144
|
508
|
|
Metal ions affect insulin-degrading enzyme activity, file e291c0d4-7e86-cddb-e053-3a05fe0aa144
|
505
|
|
Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-Nucleoside HIV-1
Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification
of a Novel Orally Bioavailable Hydrazine-Based Antiviral Agent, file e291c0d4-4ed0-cddb-e053-3a05fe0aa144
|
482
|
|
Warfarin modulates the nitrite reductase activity of ferrous human serum heme-albumin., file e291c0d5-3d72-cddb-e053-3a05fe0aa144
|
480
|
|
Copper(I) and copper(II) inhibit Abeta peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease, file e291c0d5-3e74-cddb-e053-3a05fe0aa144
|
454
|
|
CO metabolism, sensing, and signaling., file e291c0d4-804a-cddb-e053-3a05fe0aa144
|
418
|
|
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse
Transcriptase Primer Grip Region. Design, Synthesis, and Biological
Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral
Activity, file e291c0d4-4fbd-cddb-e053-3a05fe0aa144
|
403
|
|
Role of lysines in cytochrome c – cardiolipin interaction, file e291c0d5-4243-cddb-e053-3a05fe0aa144
|
395
|
|
Ibuprofen modulates allosterically NO dissociation from ferrous nitrosylated human serum heme-albumin by binding to three sites, file e291c0d3-edd7-cddb-e053-3a05fe0aa144
|
366
|
|
Reductive nitrosylation of ferric cyanide horse heart myloglobin is limited by cyanide dissociation, file e291c0d3-ee67-cddb-e053-3a05fe0aa144
|
361
|
|
Proton linkage for CO binding and redox properties of bovine lactoperoxidase, file e291c0d4-507b-cddb-e053-3a05fe0aa144
|
361
|
|
A beta(31-35) peptide induce apoptosis in PC 12 cells: Contrast with A beta(25-35) peptide and examination of underlying mechanisms, file e291c0d4-57bb-cddb-e053-3a05fe0aa144
|
353
|
|
The key role played by charge in the interaction of cytochrome c with cardiolipin, file e291c0d6-460f-cddb-e053-3a05fe0aa144
|
349
|
|
Structural bases for substrate and inhibitor recognition by matrix metaloproteinases, file e291c0d4-4fa9-cddb-e053-3a05fe0aa144
|
348
|
|
Characterization of the mechanisms by which gelatinase A, neutrophil collagenase, and membrane-type metalloproteinase MMP-14 recognize collagen I and enzymatically process the two alpha-chains, file e291c0d4-4fb1-cddb-e053-3a05fe0aa144
|
348
|
|
pH dependence of the enzymatic processing of collagen I by MMP-1 (fibroblast collagenase), MMP-2 (gelatinase A), and MMP-14 ectodomain, file e291c0d4-4ea8-cddb-e053-3a05fe0aa144
|
347
|
|
Production of antibodies and development of highly sensitive formats
of enzyme immunoassay for saxitoxin analysis, file e291c0d4-5067-cddb-e053-3a05fe0aa144
|
345
|
|
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates., file e291c0d4-8051-cddb-e053-3a05fe0aa144
|
344
|
|
Enzymatic processing by MMP-2 and MMP-9 of wild-type and mutated mouse β-dystroglycan., file e291c0d4-804f-cddb-e053-3a05fe0aa144
|
343
|
|
Peroxynitrite-mediated oxidation of ferrous carbonylated myoglobin is limited by carbon monoxide dissociation, file e291c0d3-ef09-cddb-e053-3a05fe0aa144
|
340
|
|
Multiple strategies for O2 transport: From simplicity to complexity, file e291c0d3-eebd-cddb-e053-3a05fe0aa144
|
334
|
|
The collagenolytic action of MMP-1 is regulated by the interaction
between the catalytic domain and the hinge region, file e291c0d4-4fd2-cddb-e053-3a05fe0aa144
|
334
|
|
The Collagen Binding Domain of Gelatinase A Modulates Degradation of Collagen IV by Gelatinase B, file e291c0d4-4fa2-cddb-e053-3a05fe0aa144
|
331
|
|
Isoniazide and rifampicin inhibit allosterically heme binding to albumin and peroxynitrite isomerization by heme-albumin, file e291c0d3-ef7d-cddb-e053-3a05fe0aa144
|
330
|
|
Peroxynitrite detoxification by ferryl Mycobacterium leprae truncated hemoglobin O, file e291c0d3-efa2-cddb-e053-3a05fe0aa144
|
327
|
|
Peroxynitrite scavenging by ferryl sperm whale myoglobin and human hemoglobin, file e291c0d3-edfb-cddb-e053-3a05fe0aa144
|
323
|
|
Abacavir and warfarin modulate allosterically kinetics of NO dissociation from ferrous nitrosylated human serum heme-albumin, file e291c0d3-eeb0-cddb-e053-3a05fe0aa144
|
322
|
|
The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges, file e291c0d8-ae48-cddb-e053-3a05fe0aa144
|
322
|
|
A correlation between knee cartilage degradation observed by arthroscopy and synovial proteinases activities, file e291c0d4-5061-cddb-e053-3a05fe0aa144
|
320
|
|
Cardiolipin modulates allosterically peroxynitrite detoxification by horse heart cytochrome c, file e291c0d5-83da-cddb-e053-3a05fe0aa144
|
311
|
|
An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H2O2 and UHP systems, file e291c0d4-4fae-cddb-e053-3a05fe0aa144
|
310
|
|
Reductive nitrosylation of ferric human serum heme-albumin, file e291c0d3-eef9-cddb-e053-3a05fe0aa144
|
308
|
|
Aluminum modulation of proteolytic activities, file e291c0d4-5063-cddb-e053-3a05fe0aa144
|
308
|
|
Evidence for pH-dependent multiple conformers in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding., file e291c0d4-7d4c-cddb-e053-3a05fe0aa144
|
302
|
|
Proton-linked subunit heterogeneity in ferrous nitrosylated human adult hemoglobin: an EPR study, file e291c0d4-4fb5-cddb-e053-3a05fe0aa144
|
300
|
|
Respiratory inhibition of isolated mammalian mitochondria by salivary antifungal peptide histatin-5, file e291c0d4-505d-cddb-e053-3a05fe0aa144
|
282
|
|
Catalytic peroxidation of nitrogen monoxide and peroxynitrite by globins, file e291c0d3-edf8-cddb-e053-3a05fe0aa144
|
281
|
|
Increased release and activity of matrix metalloproteinase-9 in patients with mandibuloacral dysplasia type A, a rare premature ageing syndrome, file e291c0d4-4feb-cddb-e053-3a05fe0aa144
|
272
|
|
pH-dependent redox and CO binding properties of chelated protoheme-L-histidine and protoheme-glycyl-L-histidine complexes, file e291c0d4-5077-cddb-e053-3a05fe0aa144
|
272
|
|
H2O2 and {radical dot}NO scavenging by Mycobacterium leprae truncated hemoglobin O, file e291c0d3-ef9d-cddb-e053-3a05fe0aa144
|
265
|
|
Ferrous Campylobacter jejuni truncated hemoglobin P displays an extremely high reactivity for cyanide - A comparative study, file e291c0d3-eeb3-cddb-e053-3a05fe0aa144
|
262
|
|
Salt-induced formation of the A-state of ferricytochrome c - Effect of the anion charge on protein structure, file e291c0d3-eccc-cddb-e053-3a05fe0aa144
|
252
|
|
The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome cshed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket., file e291c0d6-42f2-cddb-e053-3a05fe0aa144
|
252
|
|
Enzymatic processing of collagen IV by MMP-2 (gelatinase A) affects neutrophil migration and it is modulated by extracatalytic domains, file e291c0d4-4fb3-cddb-e053-3a05fe0aa144
|
247
|
|
Ibuprofen impairs allosterically peroxynitrite isomerization by ferric human serum heme-albumin, file e291c0d3-ee5d-cddb-e053-3a05fe0aa144
|
239
|
|
Multiphasic kinetics of myoglobin/sodium dodecyl sulfate complex formation, file e291c0d3-ee6b-cddb-e053-3a05fe0aa144
|
232
|
|
Cardiolipin drives cytochrome c proapoptotic and antiapoptotic actions, file e291c0d5-3d94-cddb-e053-3a05fe0aa144
|
232
|
|
Archaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity, file e291c0d3-ef03-cddb-e053-3a05fe0aa144
|
231
|
|
Somatostatin Modulates Insulin-Degrading-Enzyme
Metabolism: Implications for the Regulation of Microglia Activity in AD, file e291c0d4-4ea6-cddb-e053-3a05fe0aa144
|
227
|
|
Crystal structure of Mycobacterium tuberculosis zinc-dependent metalloprotease-1 (Zmp1), a metalloprotease involved in pathogenicity, file e291c0d4-4ea4-cddb-e053-3a05fe0aa144
|
218
|
|
Effect of axial coordination on the kinetics of assembly and folding of the two halves of horse heart cytochrome c, file e291c0d4-507c-cddb-e053-3a05fe0aa144
|
216
|
|
Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen, file e291c0d4-4fef-cddb-e053-3a05fe0aa144
|
213
|
|
Characterization of a globin-coupled oxygen sensor with a gene-regulating function, file e291c0d3-ec7f-cddb-e053-3a05fe0aa144
|
208
|
|
Ligation tunes protein reactivity in an ancient haemoglobin: kinetic evidence for an allosteric mechanism in methanosarcina acetivorans protoglobin, file e291c0d4-7e85-cddb-e053-3a05fe0aa144
|
197
|
|
Structural heterogeneity and ligand gating in ferric Methanosarcina acetivorans protoglobin mutants, file e291c0d7-9e75-cddb-e053-3a05fe0aa144
|
191
|
|
Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I - Role of the activation cleavage and of the hemopexin-like domain, file e291c0d4-5065-cddb-e053-3a05fe0aa144
|
182
|
|
Membrane cholesterol modulates LOX-1 shedding in endothelial cells, file e291c0d5-4d19-cddb-e053-3a05fe0aa144
|
180
|
|
Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35, file e291c0d4-5078-cddb-e053-3a05fe0aa144
|
176
|
|
Kinetic inequivalence between α and β subunits of ligand dissociation from ferrous nitrosylated human haptoglobin:hemoglobin complexes. A comparison with O2 and CO dissociation, file e291c0d8-ed4a-cddb-e053-3a05fe0aa144
|
153
|
|
Relationships of ligand binding, redox properties, and protonation in Coprinus cinereus peroxidase, file e291c0d4-505f-cddb-e053-3a05fe0aa144
|
143
|
|
Lipid peroxidation and total anitoxidant capacity in vitreous, aqueous humor and blood samples from patients with diabetric retinopathy, file e291c0d5-80b2-cddb-e053-3a05fe0aa144
|
132
|
|
Simulated microgravity induces a cellular regression of the mature phenotype in human primary osteoblasts, file e291c0d7-2d2f-cddb-e053-3a05fe0aa144
|
132
|
|
Enzymatic processing of beta-dystroglycan recombinant ectodomain by MMP-9: identification of the main cleavage site, file e291c0d4-4eaa-cddb-e053-3a05fe0aa144
|
110
|
|
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome, file e291c0d7-b22b-cddb-e053-3a05fe0aa144
|
107
|
|
Oxygen dissociation from ferrous oxygenated human hemoglobin:haptoglobin complexes confirms that in the R-state α and β chains are functionally heterogeneous, file e291c0d7-e488-cddb-e053-3a05fe0aa144
|
105
|
|
Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways, file e291c0d7-a05f-cddb-e053-3a05fe0aa144
|
104
|
|
Gelatinolytic activity in gingival crevicular fluid and saliva of growing patients with Marfan syndrome: a case-control study, file e291c0d7-e486-cddb-e053-3a05fe0aa144
|
101
|
|
Nitrosylation Mechanisms of Mycobacterium tuberculosis and Campylobacter jejuni Truncated Hemoglobins N, O, and P., file e291c0d7-c84c-cddb-e053-3a05fe0aa144
|
95
|
|
Is there a relationship between dopamine and rhegmatogenous retinal detachment?, file e291c0d8-378f-cddb-e053-3a05fe0aa144
|
95
|
|
Functional and spectroscopic characterization of Chlamydomonas reinhardtii truncated hemoglobins, file e291c0d8-13ea-cddb-e053-3a05fe0aa144
|
93
|
|
Ligand binding to the FA3-FA4 cleft inhibits the esterase-like activity of human serum albumin, file e291c0d7-c1fb-cddb-e053-3a05fe0aa144
|
92
|
|
Cardiolipin-cytochrome c complex: Switching cytochrome c from an electron-transfer shuttle to a myoglobin- and a peroxidase-like heme-protein, file e291c0d6-4334-cddb-e053-3a05fe0aa144
|
91
|
|
Structure and haem-distal site plasticity in Methanosarcina acetivorans protoglobin, file e291c0d7-a720-cddb-e053-3a05fe0aa144
|
91
|
|
Characterization of the Prostate-Specific Antigen (PSA) Catalytic Mechanism: A Pre-Steady-State and Steady-State Study., file e291c0d7-cc82-cddb-e053-3a05fe0aa144
|
90
|
|
The enzymatic processing of α-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site, file e291c0d8-0f99-cddb-e053-3a05fe0aa144
|
90
|
|
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins, file e291c0d7-ca22-cddb-e053-3a05fe0aa144
|
84
|
|
Reciprocal allosteric modulation of carbon monoxide and warfarin binding to ferrous human serum heme-albumin., file e291c0d7-f0dd-cddb-e053-3a05fe0aa144
|
82
|
|
Nitrite-reductase and peroxynitrite isomerization activities of Methanosarcina acetivorans protoglobin., file e291c0d7-a78c-cddb-e053-3a05fe0aa144
|
81
|
|
Structural bases for the regulation of CO binding in the archaeal protoglobin from Methanosarcina acetivorans, file e291c0d7-c1f9-cddb-e053-3a05fe0aa144
|
81
|
|
Proteasome activity is affected by fluctuations in insulin-degrading enzyme distribution, file e291c0d7-c1f5-cddb-e053-3a05fe0aa144
|
80
|
|
Cationic porphyrins are tunable gatekeepers of the 20S proteasome, file e291c0d8-0d88-cddb-e053-3a05fe0aa144
|
80
|
|
Citicoline in ophthalmological neurodegenerative disease: A comprehensive review, file e291c0d9-8fe8-cddb-e053-3a05fe0aa144
|
57
|
|
Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States, file e291c0d8-b106-cddb-e053-3a05fe0aa144
|
56
|
|
Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches, file e291c0d8-b210-cddb-e053-3a05fe0aa144
|
46
|
|
Dexamethasone downregulates autophagy through accelerated turn-over of the ulk-1 complex in a trabecular meshwork cells strain: Insights on steroid-induced glaucoma pathogenesis, file e291c0d9-7ba1-cddb-e053-3a05fe0aa144
|
41
|
|
Simulated microgravity induces a cellular regression of the mature phenotype in human primary osteoblasts, file e291c0d9-2a4d-cddb-e053-3a05fe0aa144
|
13
|
|
The double faced role of copper in Aβ homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration, file e291c0d7-9ef6-cddb-e053-3a05fe0aa144
|
1
|
| Totale |
31.681 |