123I-FP-CIT SPECT has been successfully used to detect the loss of dopaminergic nigrostriatal neurons in Parkinson's disease at an early stage. In this study we evaluated the capacity of 123I-FP-CIT SPECT to assess bilateral dopamine transporter (DAT) loss in de-novo hemi-Parkinson's disease (PD) patients with one-sided clinical symptoms.

Filippi, L., Manni, C., Pierantozzi, M., Brusa, L., Danieli, R., Stanzione, P., et al. (2005). 123I-FP-CIT semi-quantitative SPECT detects preclinical bilateral dopaminergic deficit in early Parkinson's disease with unilateral symptoms. NUCLEAR MEDICINE COMMUNICATIONS, 26(5), 421-426.

123I-FP-CIT semi-quantitative SPECT detects preclinical bilateral dopaminergic deficit in early Parkinson's disease with unilateral symptoms

PIERANTOZZI, MARIANGELA;STANZIONE, PAOLO;SCHILLACI, ORAZIO
2005-05-01

Abstract

123I-FP-CIT SPECT has been successfully used to detect the loss of dopaminergic nigrostriatal neurons in Parkinson's disease at an early stage. In this study we evaluated the capacity of 123I-FP-CIT SPECT to assess bilateral dopamine transporter (DAT) loss in de-novo hemi-Parkinson's disease (PD) patients with one-sided clinical symptoms.
mag-2005
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
English
Carbon Radioisotopes; Tomography, Emission-Computed, Single-Photon; Membrane Glycoproteins; Membrane Transport Proteins; Humans; Brain; Aged; Putamen; Nerve Tissue Proteins; Radionuclide Imaging; Dopamine Plasma Membrane Transport Proteins; Tropanes; Parkinson Disease; Neurons; Adult; Case-Control Studies; Iodine Radioisotopes; Middle Aged; Time Factors; Female; Male
Filippi, L., Manni, C., Pierantozzi, M., Brusa, L., Danieli, R., Stanzione, P., et al. (2005). 123I-FP-CIT semi-quantitative SPECT detects preclinical bilateral dopaminergic deficit in early Parkinson's disease with unilateral symptoms. NUCLEAR MEDICINE COMMUNICATIONS, 26(5), 421-426.
Filippi, L; Manni, C; Pierantozzi, M; Brusa, L; Danieli, R; Stanzione, P; Schillaci, O
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/99456
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