MicroRNAs (miRNA) are tiny, noncoding, small, endogenous RNAs that play major roles in neoplastic transformation and could therefore offer a better quantitative and noninvasive method for the diagnosis and prognosis of colorectal cancer (CRC) using feces. In the present study, we screened feces for 648 miRNAs and analyzed the role of miR-144* as a potential CRC diagnostic marker.

Kalimutho, M., DEL VECCHIO BLANCO, G., Di Cecilia, S., Sileri, P., Cretella, M., Pallone, F., et al. (2011). Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer. JOURNAL OF GASTROENTEROLOGY, 46(12), 1391-1402 [10.1007/s00535-011-0456-0].

Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer

DEL VECCHIO BLANCO, GIOVANNA;SILERI, PIERPAOLO;PALLONE, FRANCESCO;FEDERICI, GIORGIO;BERNARDINI, SERGIO
2011-12-01

Abstract

MicroRNAs (miRNA) are tiny, noncoding, small, endogenous RNAs that play major roles in neoplastic transformation and could therefore offer a better quantitative and noninvasive method for the diagnosis and prognosis of colorectal cancer (CRC) using feces. In the present study, we screened feces for 648 miRNAs and analyzed the role of miR-144* as a potential CRC diagnostic marker.
dic-2011
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA
Settore MED/12 - GASTROENTEROLOGIA
English
Sensitivity and Specificity; MicroRNAs; Humans; Temperature; Aged; Reverse Transcriptase Polymerase Chain Reaction; Gene Expression Regulation, Neoplastic; Aged, 80 and over; Adult; Middle Aged; Feces; Tumor Markers, Biological; Time Factors; Colorectal Neoplasms; Female; Male
Kalimutho, M., DEL VECCHIO BLANCO, G., Di Cecilia, S., Sileri, P., Cretella, M., Pallone, F., et al. (2011). Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer. JOURNAL OF GASTROENTEROLOGY, 46(12), 1391-1402 [10.1007/s00535-011-0456-0].
Kalimutho, M; DEL VECCHIO BLANCO, G; Di Cecilia, S; Sileri, P; Cretella, M; Pallone, F; Federici, G; Bernardini, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/97408
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