Antibiotic resistance, evolving and spreading among bacterial pathogens, poses a serious threat to human health. Antibiotic use for clinical, veterinary and agricultural practices provides the major selective pressure for emergence and persistence of acquired resistance determinants. However, resistance has also been found in the absence of antibiotic exposure, such as in bacteria from wildlife, raising a question about the mechanisms of emergence and persistence of resistant strains under similar conditions, and the implications for resistance control strategies. Since previous studies yielded some contrasting results, possibly due to differences in the ecological landscapes of the studied wildlife, we further investigated this issue in wildlife from a remote setting of the Galapagos archipelago.

Thaller, M.c., Migliore, L., Marquez, C., Tapia, W., Cedeño, V., Rossolini, G., et al. (2010). Tracking acquired antibiotic resistance in commensal bacteria of Galápagos land iguanas: no man, no resistance. PLOS ONE, 5(2), e8989 [10.1371/journal.pone.0008989].

Tracking acquired antibiotic resistance in commensal bacteria of Galápagos land iguanas: no man, no resistance

THALLER, MARIA CRISTINA;MIGLIORE, LUCIANA;GENTILE, GABRIELE
2010-01-01

Abstract

Antibiotic resistance, evolving and spreading among bacterial pathogens, poses a serious threat to human health. Antibiotic use for clinical, veterinary and agricultural practices provides the major selective pressure for emergence and persistence of acquired resistance determinants. However, resistance has also been found in the absence of antibiotic exposure, such as in bacteria from wildlife, raising a question about the mechanisms of emergence and persistence of resistant strains under similar conditions, and the implications for resistance control strategies. Since previous studies yielded some contrasting results, possibly due to differences in the ecological landscapes of the studied wildlife, we further investigated this issue in wildlife from a remote setting of the Galapagos archipelago.
2010
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/19 - MICROBIOLOGIA GENERALE
Settore BIO/05 - ZOOLOGIA
Settore BIO/07 - ECOLOGIA
English
Con Impact Factor ISI
Environmental Monitoring; Ecosystem; Microbial Sensitivity Tests; Bacteria; Iguanas; Geography; Bacterial Proteins; Animals; Ecuador; Anti-Bacterial Agents; Humans; Drug Resistance, Bacterial
Thaller, M.c., Migliore, L., Marquez, C., Tapia, W., Cedeño, V., Rossolini, G., et al. (2010). Tracking acquired antibiotic resistance in commensal bacteria of Galápagos land iguanas: no man, no resistance. PLOS ONE, 5(2), e8989 [10.1371/journal.pone.0008989].
Thaller, Mc; Migliore, L; Marquez, C; Tapia, W; Cedeño, V; Rossolini, G; Gentile, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/9688
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