IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).

Orchard, S., Ammari, M., Aranda, B., Breuza, L., Briganti, L., Broackes Carter, F., et al. (2014). The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. NUCLEIC ACIDS RESEARCH, 42(Database issue), D358-D358-63 [10.1093/nar/gkt1115].

The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases

LICATA, LUANA;CESARENI, GIOVANNI;
2014-01-01

Abstract

IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).
gen-2014
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/18 - GENETICA
English
Software; Protein Interaction Mapping; Databases, Protein; Internet
Orchard, S., Ammari, M., Aranda, B., Breuza, L., Briganti, L., Broackes Carter, F., et al. (2014). The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. NUCLEIC ACIDS RESEARCH, 42(Database issue), D358-D358-63 [10.1093/nar/gkt1115].
Orchard, S; Ammari, M; Aranda, B; Breuza, L; Briganti, L; Broackes Carter, F; Campbell, N; Chavali, G; Chen, C; del Toro, N; Duesbury, M; Dumousseau, M; Galeota, E; Hinz, U; Iannuccelli, M; Jagannathan, S; Jimenez, R; Khadake, J; Lagreid, A; Licata, L; Lovering, R; Meldal, B; Melidoni, A; Milagros, M; Peluso, D; Perfetto, L; Porras, P; Raghunath, A; Ricard Blum, S; Roechert, B; Stutz, A; Tognolli, M; van Roey, K; Cesareni, G; Hermjakob, H
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/96339
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