The viral and cellular forms of the Src protein tyrosine kinases take a prototypic role in oncology and signal transduction research, by virtue of being holders of an impressive number of 'firsts'. Our understanding of the biochemistry and physiology of Src has therefore always been used as a reference for our general advancement in the field of protein phosphorylation and growth control. The recent solution of the crystal structure of two members of the Src family represents a milestone in these disciplines and, as usual, provides a general lookout post for developments to come.

Superti Furga, G., Gonfloni, S. (1997). A crystal milestone: the structure of regulated Src. BIOESSAYS, 19(6), 447-450 [10.1002/bies.950190602].

A crystal milestone: the structure of regulated Src

GONFLONI, STEFANIA
1997-06-01

Abstract

The viral and cellular forms of the Src protein tyrosine kinases take a prototypic role in oncology and signal transduction research, by virtue of being holders of an impressive number of 'firsts'. Our understanding of the biochemistry and physiology of Src has therefore always been used as a reference for our general advancement in the field of protein phosphorylation and growth control. The recent solution of the crystal structure of two members of the Src family represents a milestone in these disciplines and, as usual, provides a general lookout post for developments to come.
giu-1997
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/18 - GENETICA
English
Con Impact Factor ISI
Protein Folding; Structure-Activity Relationship; src-Family Kinases; Crystallization; Animals; Humans
Superti Furga, G., Gonfloni, S. (1997). A crystal milestone: the structure of regulated Src. BIOESSAYS, 19(6), 447-450 [10.1002/bies.950190602].
Superti Furga, G; Gonfloni, S
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/9223
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