The same factor, ABF1, binds to the promoters of the two gene copies (L2A and L2B) coding for the ribosomal protein L2 in Saccharomyces cerevisiae. In vitro binding experiments and in vivo functional analysis showed that the different affinities of the L2A and L2B promoters for the ABF1 factor are responsible for the differential transcriptional activities of the two gene copies. The presence of ABF1-binding sites in front of many housekeeping genes suggests a general role for ABF1 in the regulation of gene activity.
Della Seta, F., Ciafré, S.A., Marck, C., Santoro, B., Presutti, C., Sentenac, A., et al. (1990). The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae. MOLECULAR AND CELLULAR BIOLOGY, 10(5), 2437-2441.
Tipologia: | Articolo su rivista |
Citazione: | Della Seta, F., Ciafré, S.A., Marck, C., Santoro, B., Presutti, C., Sentenac, A., et al. (1990). The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae. MOLECULAR AND CELLULAR BIOLOGY, 10(5), 2437-2441. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore BIO/13 |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | mag-1990 |
Titolo: | The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae |
Autori: | |
Autori: | Della Seta, F; Ciafré, SA; Marck, C; Santoro, B; Presutti, C; Sentenac, A; Bozzoni, I |
Appare nelle tipologie: | 01 - Articolo su rivista |