Aloe-emodin (AE), a plant derived anthraquinone, has been shown to have anticancer activity in various human cancer cell lines. We have recently reported that AE possesses a differentiative potential on melanoma cells. The purpose of this study was to investigate the possible modulation of defined markers of monocytic differentiation of AE on human U937 cell line.

Tabolacci, C., Oliverio, S., Lentini, A., Rossi, S., Galbiati, A., Montesano, C., et al. (2011). Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells. LIFE SCIENCES, 89(21-22), 812-820 [10.1016/j.lfs.2011.09.008].

Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells

OLIVERIO, SERAFINA;LENTINI, ALESSANDRO;MONTESANO, CARLA;MATTIOLI, PALMA;PROVENZANO, BRUNO;BENINATI, SIMONE
2011-11-21

Abstract

Aloe-emodin (AE), a plant derived anthraquinone, has been shown to have anticancer activity in various human cancer cell lines. We have recently reported that AE possesses a differentiative potential on melanoma cells. The purpose of this study was to investigate the possible modulation of defined markers of monocytic differentiation of AE on human U937 cell line.
21-nov-2011
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore BIO/06 - ANATOMIA COMPARATA E CITOLOGIA
Settore MED/04 - PATOLOGIA GENERALE
English
Con Impact Factor ISI
Macrophages; Cell Movement; Ornithine Decarboxylase; Apoptosis; Humans; Transglutaminases; Cell Differentiation; Enzyme Inhibitors; Oxidoreductases Acting on CH-NH Group Donors; Protoporphyrins; Cell Proliferation; Biogenic Polyamines; Antigens, CD14; Nitric Oxide; Indicators and Reagents; Nitrites; Nitroblue Tetrazolium; Cytokines; Transport Vesicles; Phagocytosis; Anthraquinones; U937 Cells; Antigens, CD11b; Cell Adhesion
Tabolacci, C., Oliverio, S., Lentini, A., Rossi, S., Galbiati, A., Montesano, C., et al. (2011). Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells. LIFE SCIENCES, 89(21-22), 812-820 [10.1016/j.lfs.2011.09.008].
Tabolacci, C; Oliverio, S; Lentini, A; Rossi, S; Galbiati, A; Montesano, C; Mattioli, P; Provenzano, B; Facchiano, F; Beninati, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/91550
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