The possible neuroprotective effects of classic and new antiepileptic drugs on the electrophysiological changes induced by in vitro ischemia on striatal neurons were investigated. In particular, the aim of the study was to correlate the putative neuroprotective effects with the action of these drugs on fast sodium (Na+) and high-voltage-activated (HVA) calcium (Ca2+) currents.

Costa, C., Martella, G., Picconi, B., Prosperetti, C., Pisani, A., Di Filippo, M., et al. (2006). Multiple mechanisms underlying the neuroprotective effects of antiepileptic drugs against in vitro ischemia. STROKE, 37(5), 1319-1326 [10.1161/01.STR.0000217303.22856.38].

Multiple mechanisms underlying the neuroprotective effects of antiepileptic drugs against in vitro ischemia

MARTELLA, GIUSEPPINA;PISANI, ANTONIO;BERNARDI, GIORGIO;CALABRESI, PAOLO
2006-05-01

Abstract

The possible neuroprotective effects of classic and new antiepileptic drugs on the electrophysiological changes induced by in vitro ischemia on striatal neurons were investigated. In particular, the aim of the study was to correlate the putative neuroprotective effects with the action of these drugs on fast sodium (Na+) and high-voltage-activated (HVA) calcium (Ca2+) currents.
mag-2006
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Rats; Animals; Carbamazepine; Excitatory Postsynaptic Potentials; Fructose; Potassium; Brain Ischemia; Electrophysiology; Valproic Acid; Calcium Signaling; Anticonvulsants; Ion Transport
Costa, C., Martella, G., Picconi, B., Prosperetti, C., Pisani, A., Di Filippo, M., et al. (2006). Multiple mechanisms underlying the neuroprotective effects of antiepileptic drugs against in vitro ischemia. STROKE, 37(5), 1319-1326 [10.1161/01.STR.0000217303.22856.38].
Costa, C; Martella, G; Picconi, B; Prosperetti, C; Pisani, A; Di Filippo, M; Pisani, F; Bernardi, G; Calabresi, P
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/88300
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