It is clear that in many patients, autoantibodies are produced after a myocardial injury. It is less clear whether such autoantibodies have clinical significance. In addition, infection with specific microbial agents may also produce antimyocardial antibodies. Interestingly, in nested subgroups of patients, the presence of antimyocardial antibodies is predictive of clinical outcome including disease progression. However, further studies need to be done and improvements are required for the actual immunoassays. Copyright © 2014 Elsevier B.V. All rights reserved.
Rinaldi, M., Perricone, R., Perricone, C., Shoenfeld, Y. (2014). Antimyocardial Autoantibodies (AMCA). In Autoantibodies (pp. 349-355). Elsevier B.V. [10.1016/B978-0-444-56378-1.00042-3].
Antimyocardial Autoantibodies (AMCA)
PERRICONE, ROBERTO;
2014-01-01
Abstract
It is clear that in many patients, autoantibodies are produced after a myocardial injury. It is less clear whether such autoantibodies have clinical significance. In addition, infection with specific microbial agents may also produce antimyocardial antibodies. Interestingly, in nested subgroups of patients, the presence of antimyocardial antibodies is predictive of clinical outcome including disease progression. However, further studies need to be done and improvements are required for the actual immunoassays. Copyright © 2014 Elsevier B.V. All rights reserved.Questo articolo è pubblicato sotto una Licenza Licenza Creative Commons